Download or read book Implications of myocardial dysfunction before and after aortic valve intervention written by Henrik Hultkvist and published by Linköping University Electronic Press. This book was released on 2019-05-13 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: BACKGROUND Postoperative heart failure in the setting of aortic valve surgery results in poor long-term survival. We hypothesized that there could be a myocardial factor that is not addressed by risk scores currently available. We speculated that this myocardial factor could be diastolic dysfunction. By evaluating postoperative heart failure, the EuroSCORE, the NT-proBNP level, and diastolic function, we might achieve a deeper understanding of the outcome for individuals with postoperative heart failure. METHODS This research project was built upon four cohort studies. The first two studies (I and II) were retrospective in nature, and studies III and IV were prospective, observational, and longitudinal. All work was based on data from clinical and national databases. In Study I, we compared the outcome of patients with or without postoperative heart failure, evaluated according to the preoperative risk score. In Study II, we explored the effect of underlying heart disease on the preoperative level of NT-proBNP and the relationships between NT-proBNP and severe postoperative heart failure and short-term mortality. In Study III, we described the dynamics of NT-proBNP, from a preoperative evaluation to a six-month follow-up, in patients that underwent one of two different procedures: a surgical aortic valve replacement and a transcatheter implantation. We related both pre- and postprocedural NT-proBNP levels to one-year mortality. In Study IV, we evaluated diastolic function in patients that underwent surgical aortic valve replacement and its influence on outcome. We also evaluated NT-proBNP levels and postoperative heart failure as predictors of long-term mortality. RESULTS Study I This study included 397 patients that underwent isolated surgical aortic valve replacements. Of these, 45 patients (11%) were treated for postoperative heart failure. With an average follow-up of 8.1 years (range 5.2-11.2), among patients at low risk (EuroSCORE≤7), the crude five-year survival rates were 58% in patients with postoperative heart failure and 89% in those without postoperative heart failure (p<0.001). Among patients with postoperative heart failure, those classified as low risk had the same poor long-term prognosis as those classified as high risk (EuroSCORE>7). In the high risk group, survival rates were similar between patients with or without postoperative heart failure (57% vs. 64%; p=0.60). Study II This study included a cohort of 2978 patients with coronary artery disease, aortic stenosis, and mitral regurgitation. Preoperative NTproBNP levels were found to be 1.7-fold higher in patients with aortic stenosis than in patients with coronary artery disease and 1.4-fold higher in patients with mitral regurgitation than in patients with coronary disease. The power of preoperative NT-proBNP for predicting severe postoperative heart conditions was good among patients with coronary heart disease and patients with mitral regurgitation, but not as good among patients with aortic stenosis. NT-proBNP also showed good discriminating power for short-term mortality among patients with coronary artery disease. Moreover, NT-proBNP was found to be an independent predictor for both severe postoperative heart failure and short-term mortality in patients with coronary artery disease. Study III This study included 462 patients that underwent preoperative evaluations for aortic valve disease. Aortic valve interventions elicited a rise in NT-proBNP that was more pronounced in patients undergoing surgical aortic valve replacement compared to patients undergoing transcatheter valve implantation. No deterioration in NT-proBNP was observed during the waiting time before the intervention, despite a median duration of four months. At six months after the intervention, NT-proBNP levels had decreased to or below the preoperative levels in all groups. Among patients that received surgical aortic valve replacements, pre-and early postoperative NT-proBNP levels showed good discriminatory power for oneyear mortality. This discriminatory power was not observed among patients that had undergone a transcatheter procedure; those patients had higher levels of both pre- and postoperative NT-proBNP compared to patients that had undergone surgery. Study IV We evaluated 273 patients that underwent aortic valve surgery. High left ventricular filling pressure was present in 22% (n=54) of patients at the time of surgery. At six months after surgery, diastolic function deteriorated in 24/193 (12%) patients and improved in 27/54 (50%) patients. Diastolic dysfunction was not found to be associated with long-term mortality. However, both postoperative heart failure and preoperative NTproBNP levels were associated with increases in long-term mortality. In a multivariable Cox analysis, NT-proBNP remained predictive of long-term mortality. CONCLUSION Postoperative heart failure contributed to long-term mortality, even in patients considered to be at low risk preoperatively. Our results suggested that pressure overload, followed by a volume overload led to a NTproBNP response that was more pronounced than the ischemia response. Elevated levels of NT-proBNP were associated with both short- and long-term mortality. In these studies, we could not corroborate the notion that high left ventricular filling pressure was associated with long-term mortality.

Download or read book Degenerative Aortic Valve Disease its Mechanism on Progression its Effect on the Left Ventricle and the Postoperative Results written by Wilhelm Peter Mistiaen and published by Bentham Science Publishers. This book was released on 2013-01-10 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Degenerative aortic valve disease is the most prominent cardiac valve disease in Western societies. This volume describes some of the more important issues and problems for this condition: its progressive character and the underlying mechanisms of this progression diagnostic difficulties 1) ascertainment of valvular origin of symptoms in elderly; 2) the challenge of the low output – low gradient syndrome; 3) moderate aortic valve calcification during CABG; 4) prediction of the rate of progression (who will need surgery on short term and who not). the burden on the left ventricle and its consequences (danger of postponement of surgery) the effect and the modalities (access, types of valves) of surgical treatment on survival (and QoL) the mode of registering postoperative complications determining predictors for valve related, non-valve related cardiac and non-cardiac postoperative complications. The e-book is a unique presentation, specific to degenerative aortic valve disease and its treatment including information about ways to deal with the progressive character of the disease (autophagy as a mode of cell death). Cardiologists still avoid or delay referring patients to the surgeon for the sake of age, left ventricular function or co-morbidity. Therefore, the e-book benefits readers by addressing the above issue and providing critical information for changing referral policy, which would ultimately enhance postoperative survival of patients suffering from heart valve disease."

Download or read book Aortic Valve Transcatheter Intervention written by Marco Zimarino and published by John Wiley & Sons. This book was released on 2021-02-23 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Practical Guide to Prevention and Treatment of Complications during Transcatheter Aortic Valve Implantation Calcific aortic stenosis (AS) is the most common heart valve anomaly, with a largely age-dependent prevalence, a calculated annual incidence rate in the range of 4-5% in general populations and up to 6% in patients aged 75 years and over. Surgical aortic valve replacement (SAVR) was previously the only option available to patients with symptomatic, severe aortic stenosis. After the first-in-human transcatheter aortic valve implantation (TAVI) was performed by Alain Cribier in 2002, the treatment strategy for patients with symptomatic AS has been revolutionized. Since then, TAVI has grown exponentially, as a result of accruing evidence demonstrating safety and efficacy, and reduced invasiveness compared with SAVR. TAVI devices are continuously expanding to include several valve design options. As this strategy is continuously evolving to treat younger patients and lower-risk populations, aside from the long-term durability of the valve systems, procedural safety will become the focus of newer-generation devices. This book is a practical handbook devoted to the optimization of TAVI procedures, through a focused containment of complications. Through an integrated evaluation of the clinical status, imaging techniques and laboratory findings, the authors provide readers with clear messages on preventive and therapeutic recommendations.

Download or read book Aortic Valve Disease An Issue of Cardiology Clinics E Book written by Marie-Annick Clavel and published by Elsevier Health Sciences. This book was released on 2019-12-03 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Cardiology Clinics, guest edited by Drs. Marie-Annick Clavel and Philippe Pibarot, focuses on Aortic Valve Disease. Articles in this issue include, but are not limited to: Pathophysiology of Aortic Stenosis and future perspectives for medical therapy, Assessment of Aortic Stenosis Severity, Assessment of Cardiac Damage in Aortic stenosis, Aortic Stenosis with Other Concomitant Valvular Disease (AR, MR, TR), Biomarker in Aortic Stenosis, Aortic stenosis guidelines: evidence gaps and changing concepts, Heart Valve Clinics and Heart Valve Centers, Frailty and Multi-Comorbidities in Aortic Stenosis, Procedures and Outcomes of Surgical Aortic Valve Replacement, Patient selection and Work-up for Transcatheter Aortic Valve Replacement, Procedures and Outcomes of Transcatheter Aortic Valve Replacement, Sex differences in the Pathophysiology, Diagnosis, and Management of Aortic Stenosis, Implications of Aortic stenosis in Pregnancy and Non-Cardiac Surgery.

Download or read book Transcatheter Aortic Valve Replacement Program Development written by Marian C. Hawkey and published by Lippincott Williams & Wilkins. This book was released on 2019-01-11 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Launch and cultivate a successful program for the innovative procedure poised to become the standard for patients with aortic stenosis (AS) with Transcatheter Aortic Valve Replacement (TAVR) Program Development: A Guide for the Heart Team. Written by leaders in the field, this clinical instruction manual is the first to consolidate evidence, guidelines, and best practices for the TAVR care pathway from referral to follow-up. This is a must-have for clinicians—nurses, physicians, and allied health professionals—as well as administrative leadership and staff involved in TAVR programs. The text offers a comprehensive view of the TAVR program organized to support staff and quality, and positioned to grow on pace with evolving indications, regulations, technology, and patient needs.

Download or read book Atlas of Cardiac Surgical Techniques E Book written by Frank W. Sellke and published by Elsevier Health Sciences. This book was released on 2018-01-31 with total page 763 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get expert, step-by-step guidance on a wide variety of both open and interventional cardiac surgical techniques. Atlas of Cardiac Surgical Techniques, 2nd Edition, helps you expand your surgical repertoire and hone your skills with a vividly illustrated, easy-to-navigate text and pearls and pitfalls throughout. This revised atlas covers the surgical procedures you need to master, including minimally invasive techniques, robotic surgery, aortic dissection, and much more. - Seven brand-new chapters cover Hybrid Coronary Revascularization, Aortic Valve Repair Techniques, Transcatheter Aortic Valve Replacement, Robotic Mitral Valve Surgery, Surgery for Hypertrophic Cardiomyopathy, Approaches and Techniques to Extra-Corporeal Membrane Oxygenation, and Pulmonary Endarterectomy. - Multiple new contributing authors offer a fresh perspective in their areas of expertise. - A consistent chapter format guides you quickly from surgical anatomy and preoperative considerations through operative steps and postoperative care. - Online videos highlight key stages of surgical procedures. - More than 400 full-color images, line drawings, and intraoperative photographs clearly depict the step-by-step progression of procedures. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Download or read book Minimally Invasive Aortic Valve Surgery written by Hunaid A. Vohra and published by Nova Science Publishers. This book was released on 2016-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Minimally invasive aortic valve surgery is a relatively new field which cardiac surgeons are increasingly embracing, and patients and cardiologists are demanding this with more enthusiasm. This is a current subject of great interest with contemporary results already present and more are awaited. This book describes the process through the set-up of a minimally invasive aortic valve surgery program, pertinent investigations, patient selection, different approaches (including endoscopic and robotic), cardio-pulmonary bypass, re-operations and their application with rapid deployment and aortic vascular surgery. This book is intended for all training cardiac surgeons and cardiologists, consultant cardiac surgeons and cardiologists, anaesthetists, intensive care specialists and perfusionists. This is the first book authored exclusively on this subject. The three editors are leading authorities on this subject in the UK and are mentors for many surgical programs. Every chapter is authored by experts in this particular aspect of minimally invasive aortic valve surgery. These surgeons are mainly from the United States, Australia and Europe.

Download or read book Aortic Valve Transcatheter Intervention written by Marco Zimarino and published by John Wiley & Sons. This book was released on 2021-05-07 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aortic Valve Transcatheter Intervention Calcific aortic stenosis (AS) is the most common heart valve anomaly, with a largely age-dependent prevalence, a calculated annual incidence rate in the range of 4-5% in general populations and up to 6% in patients aged 75 years and over. Surgical aortic valve replacement (SAVR) was previously the only option available to patients with symptomatic, severe aortic stenosis. After the first-in-human transcatheter aortic valve implantation (TAVI) was performed by Alain Cribier in 2002, the treatment strategy for patients with symptomatic AS has been revolutionized. Since then, TAVI has grown exponentially, as a result of accruing evidence demonstrating safety and efficacy, and reduced invasiveness compared with SAVR. TAVI devices are continuously expanding to include several valve design options. As this strategy is continuously evolving to treat younger patients and lower-risk populations, aside from the long-term durability of the valve systems, procedural safety will become the focus of newer-generation devices. This book is a practical handbook devoted to the optimization of TAVI procedures, through a focused containment of complications. Through an integrated evaluation of the clinical status, imaging techniques and laboratory findings, the authors provide readers with clear messages on preventive and therapeutic recommendations.

Download or read book Diagnosis and Management of Hypertrophic Cardiomyopathy written by Barry J. Maron and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosis and Management of Hypertrophic Cardiomyopathy is aunique, multi-authored compendium of information regarding thecomplexities of clinical and genetic diagnosis, natural history,and management of hypertrophic cardiomyopathy (HCM)—the mostcommon and important of the genetic cardiovasculardiseases—as well as related issues impacting the health oftrained athletes. Edited by Dr. Barry J. Maron, a world authority on HCM, and withmajor contributions from all of the international experts in thisfield, this book provides a single comprehensive source ofinformation concerning HCM. Recent advances in the field arediscussed, including the importance of left ventricular outflowtract obstruction, the use of implantable defibrillators for theprevention of sudden death in young people, definition of thegenetic basis for HCM and its role in clinical diagnosis and riskstratification, the development of more precise strategies forassessing the level of risk for sudden death among all patientswith HCM, and the evolution of invasive interventions for heartfailure symptoms, such as surgical management and its alternatives(alcohol septal ablation and dual-chamber pacing). Key Features: Contributions from all experts in the field,representing diverse viewpoints regarding this heterogeneousdisease and related issues in athletes Information to dispel misunderstandings regarding issuesassociated with HCM and cardiovascular disease in athletes The only comprehensive source of information available on thetopic

Download or read book Aortopathy written by Koichiro Niwa and published by Springer. This book was released on 2017-02-09 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first textbook to focus on Aortopathy, a new clinical concept for a form of vasculopathy. The first section of the book starts from discussing general concept and history of Aortopathy, and then deals with its pathophysiology, manifestation, intrinsic factor, clinical implication, management and prevention. The second part closely looks at various disorders of the Aortopathy such as bicuspid aortic valve and coarctation of aorta. The book editors have published a lot of works on the topic and have been collecting relating data in the field of congenital heart disease for the past 20 years, thus present the book with confidence. The topic - an association of aortic pathophysiological abnormality, aortic dilation and aorto-left ventricular interaction - is getting more and more attention among cardiovascular physicians. This is the first book to refer for cardiologists, pediatric cardiologists, surgeons, ACHD specialists, etc. to acquire thorough knowledge on Aortopathy.

Download or read book Transcatheter Aortic Valve Implantation written by Arturo Giordano and published by Springer. This book was released on 2019-07-01 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive information on transcatheter aortic valve implantation (TAVI), which was introduced for the treatment of aortic valve disease less than two decades ago. It explains how TAVI has delivered satisfactory results even in high and intermediate risk patients and outlines how it continues to evolve, thus requiring awareness of state of the art approaches to indication, risk stratification, device choice, procedure, and follow-up. In addition, it reports on the complex and multidisciplinary approach needed to maximize the efficacy, safety, and appropriateness of TAVI, providing detailed clinical, interventional and surgical perspectives focusing on the development of this cardiovascular intervention. Starting with the history of TAVI, addressing the interventional anatomy of aortic valve disease, and reporting on the expert authors’ day-to-day experiences, this highly informative book offers an essential update for all cardiologists and surgeons interested in transcatheter aortic valve implantation, as well as any clinician, decision-maker and stakeholder involved in patient selection, procedural management, and follow-up.

Download or read book 3D Echocardiography written by Takahiro Shiota and published by CRC Press. This book was released on 2020-12-29 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the second edition of this volume, 3D echocardiography has penetrated the clinical arena and become an indispensable tool for patient care. The previous edition, which was highly commended at the British Medical Book Awards, has been updated with recent publications and improved images. This third edition has added important new topics such as 3D Printing, Surgical and Transcatheter Management, Artificial Valves, and Infective Endocarditis. The book begins by describing the principles of 3D echocardiography, then proceeds to discuss its application to the imaging of • Left and Right Ventricle, Stress Echocardiography • Left Atrium, Hypertrophic Cardiomyopathy • Mitral Regurgitation with Surgical and Nonsurgical Procedures • Mitral Stenosis and Percutaneous Mitral Valvuloplasty • Aortic Stenosis with TAVI / TAVR • Aortic and Tricuspid Regurgitation • Adult Congenital Heart Disease, Aorta • Speckle Tracking, Cardiac Masses, Atrial Fibrillation KEY FEATURES In-depth clinical experiences of the use of 3D/2D echo by world experts Latest findings to demonstrate clinical values of 3D over 2D echo One-click view of 263 innovative videos and 352 high-resolution 3D/2D color images in a supplemental eBook.

Download or read book Essential Clinical Anesthesia written by Charles Vacanti and published by Cambridge University Press. This book was released on 2011-07-11 with total page 1191 pages. Available in PDF, EPUB and Kindle. Book excerpt: The clinical practice of anesthesia has undergone many advances in the past few years, making this the perfect time for a new state-of-the-art anesthesia textbook for practitioners and trainees. The goal of this book is to provide a modern, clinically focused textbook giving rapid access to comprehensive, succinct knowledge from experts in the field. All clinical topics of relevance to anesthesiology are organized into 29 sections consisting of more than 180 chapters. The print version contains 166 chapters that cover all of the essential clinical topics, while an additional 17 chapters on subjects of interest to the more advanced practitioner can be freely accessed at www.cambridge.org/vacanti. Newer techniques such as ultrasound nerve blocks, robotic surgery and transesophageal echocardiography are included, and numerous illustrations and tables assist the reader in rapidly assimilating key information. This authoritative text is edited by distinguished Harvard Medical School faculty, with contributors from many of the leading academic anesthesiology departments in the United States and an introduction from Dr S. R. Mallampati. This book is your essential companion when preparing for board review and recertification exams and in your daily clinical practice.

Download or read book The ESC Textbook of Cardiovascular Medicine written by A. John Camm and published by . This book was released on 2019 with total page 3198 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book ASE s Comprehensive Echocardiography written by Steven A Goldstein and published by Elsevier Health Sciences. This book was released on 2015-01-08 with total page 913 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written and endorsed by world experts from the American Society of Echocardiography (ASE), this unique multimedia resource uses text, case studies, and online components to cover the latest uses of echocardiography, including the most recent 2D and 3D advances. Unlike other existing textbooks in echocardiography, including the predecessor of this volume, entitled Dynamic Echocardiography, this 2nd edition, with its new title, covers a full range of topics, reflected in its 200 chapters that include essential material in a succinct format. Dr. Roberto M. Lang and his expert colleagues provide everything you need to assess cardiac anatomy and function and obtain clinically useful, noninvasive information for more accurate diagnosis and evaluation of heart disease. Tap into the knowledge and skills of a team of experts from the ASE, led by world-renowned authorities in echocardiography. Consult this title on your favorite e-reader. Get fully up to date with the latest echo practice guidelines and advanced technologies, including 3D echocardiography and myocardial strain. Gain a better understanding of the latest methods to assess cardiac chamber size and function, valvular stenosis/regurgitation, cardiomyopathies, coronary artery disease, complications of myocardial infarction, and much more – all in a practical, well-illustrated brief yet comprehensive format extensively supported by multimedia material. Stay up to date with hot topics in this rapidly evolving field: interventional/intraoperative echocardiography, transesophageal echocardiography, cardiac resynchronization therapy, and more.

Download or read book Myocardial Protection written by Tomas A. Salerno and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.

Download or read book ASE s Comprehensive Strain Imaging E Book written by Thomas H. Marwick and published by Elsevier Health Sciences. This book was released on 2021-05-01 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strain imaging (also known as speckle-tracking echocardiography or STE) is a rapidly growing, affordable, and versatile cardiac imaging technology of great interest to clinicians in both inpatient and outpatient settings. ASE's Comprehensive Strain Imaging is the first reference designed to help you master a wide range of strain imaging/STE applications, including screening, diagnosis, treatment, and follow up. Written and edited by a team of international experts from the American Society of Echocardiography (ASE), this new resource provides the information you need to optimize imaging acquisition and analysis using this important new echocardiography method. Covers step-by-step techniques on how to use strain imaging with expert tips on nuances, pitfalls, and clinical decision making. Discusses the growing range of strain imaging applications for assessing diastolic function, atrial function, heart failure, arterial disease, valve disease, hypertrophy, and other common cardiovascular conditions. Provides up-to-date information on screening and follow up of patients who receive cardio-toxic oncologic agents during cancer treatment and evaluation of patients with cardiomyopathy, heart failure, arterial disease, valve disease, implantable pacemakers, pericardial disease, hypertrophy, ischemic disease, and chest radiation. Includes more than 150 images using the latest strain imaging technology, as well as videos that depict evaluation and monitoring of patients with cardiomyopathies. Addresses future applications, including elastography.