Download or read book Hypothermia and Cerebral Ischemia written by Carolina M. Maier and published by Springer Science & Business Media. This book was released on 2003-10-17 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of the scientific and clinical studies that have led to the resurgence of interest in hypothermia as a neuroprotective strategy in the treatment of stroke and traumatic brain injury. Topics of special importance include intraoperative and intensive care management of hypothermia-treated patients, a critical look at the potential for combining hypothermia with pharmacotherapy, and an update on the latest technological advances that have made hypothermic treatment possible in today's clinical setting.
Download or read book Hypothermia and Cerebral Ischemia written by Carolina M. Maier and published by . This book was released on 2014-01-15 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Therapeutic Hypothermia written by Samuel Tisherman and published by Springer Science & Business Media. This book was released on 2007-04-03 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic Hypothermia will provide a review of the subject, in particular, resuscitative hypothermia and include known mechanisms of action and results from both mechanistic and outcome laboratory studies and clinical trials. Cooling methods and potential side effects of hypothermia will be addressed as well as recommendations for future laboratory and clinical research. This volume will be of interest to both the researcher interested in therapeutic hypothermia as well as the clinician interested in the potential use of therapeutic hypothermia in their patient population.
Download or read book Brain Hypothermia written by N. Hayashi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid progress in technology and its application to diagnosis and monitoring of brain tissue temperature and metabolism have resulted in advances in the therapy for critically brain-injured patients and breakthroughs in understanding the pathophysiology of brain damage. The latest concept of brain hypothermia therapy clarifies targets such as brain thermal pooling, masking brain hypoxia associated with catecholamine surge, the metabolic shift from glucose to lipids, and selective radical damage of dopamine in the central nervous system. This volume explains the mechanism of brain injury and how brain hypothermia treatment differs from other hypothermia therapy in four major sections: Brain Injury Mechanism, Pathophysiology of Hypothermia, Basic Research of Hypothermia Treatment, and Clinical Studies of Brain Hypothermia. The book is a valuable source for practitioners and researchers in neurosurgery and neurology and in critical care and emergency medicine.
Download or read book Hypothermia for Acute Brain Damage written by N. Hayashi and published by Springer Science & Business Media. This book was released on 2012-02-02 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Brain Hypothermia Symposium 2004, held in Tokyo, was a forum for many of the world’s leading researchers and clinicians to present and discuss developments on the cutting edge of this most promising of neurological therapies. With a view to sharing this knowledge and encouraging the spread of new techniques, the editors have compiled these proceedings covering the latest technology and methods. Topics include brain thermo-pooling, hemoglobin-dysfunction-associated neuronal hypoxia, intensive care management of brain hypothermia for severely brain-injured patients, new findings not yet recorded in animal models, and control of hypothermia-associated immune crises. Also included are advanced clinical results from trauma, stroke, and cardiac arrest patients. The result is a volume that will be a valuable resource for professionals in the fields of emergency treatment, critical medicine, and neurosurgery.
Download or read book Therapeutic Hypothermia in Brain Injury written by Farid Sadaka and published by BoD – Books on Demand. This book was released on 2013-01-30 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the evidence behind the application of Therapeutic Hypothermia on patients with injury to the brain and spinal cord, that includes ischemia reperfusion after cardiac arrest or asphyxiation, traumatic brain injury, acute ischemic stroke, hemorrhagic stroke, refractory intracranial hypertension, cerebral edema in acute liver failure, subarachnoid hemorrhage, as well as spinal cord injury. This book discusses the mechanisms by which therapeutic hypothermia can mitigate the pathophysiologies responsible for secondary brain injury, and provides information to help guide this treatment with regard to timing, depth, duration, and management of side-effects. The book also discusses the methods and technologies used to induce and maintain therapeutic hypothermia. It also describes how hypothermia can influence the ability to prognosticate these injured patients and provides grounds for future directions in the application of and research with therapeutic hypothermia.
Download or read book Therapeutic Hypothermia After Cardiac Arrest written by Justin B. Lundbye and published by Springer Science & Business Media. This book was released on 2012-07-25 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic hypothermia has emerged as a very important treatment option for patients with cardiac arrest as it provides significant protection from developing neurologic injury once the patient has been successfully resuscitated. Studies have demonstrated over 15% absolute risk reduction in death and neurologic injury using this therapy. Although hospitals and medical centers have become familiar with this important intervention it still remains greatly under utilized due to an experience and lack of resources to safely and effectively deploy such a program. The objective of this book is to educate and familiarize both providers and institutions as to how to develop and deploy and provide therapeutic hypothermia to their patients. The current knowledge for this is provided by speakers and national experts and also by literature review. There are several courses being provided on this as well throughout the US. These are good venues for people to come and see and get hands on experience, but there still needs to be a concrete book with references on how to go about getting this program started.
Download or read book Cerebral Blood Flow written by Michael Pinsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral Blood Flow: Quantifying Consciousness Although the heart may be the source of energy needed to generate blood flow,and other organs absolutely essential for normal living,the brain is the reason we are alive. The collected book chapters are aimed at addressing this most fundamental organ and its blood flow. These papers reflect detailed descriptions of similar topics presented over a two-day period as part of the 5th International Symposium on Applied Physiology of the Peripheral Circulation held in Pittsburgh, Pennsylvania, in June 2000. The symposium and this volume were organized into four distinct groupings that follow in a logical fashion. The initial papers focus on the basic unique physiology and pathophysiology of the cerebral circulation, including a historical reviewof the means to measure cerebral blood flow and its implications of the past 30 years. Dr. Walter D. Obrist was one of the original investigators to use radiolabeled markers to assess cerebral blood flow. His equations and initial studies form an impressive introduction to where we are now. As with much of the body's special organs, the brain too has many circulatory features unique to itself.These include the unique blood-brain barrier function ofthe endothelium, local neural regulation control, and intracranial pressure effects. These special issues,plus genetic factors that may predispose individuals to developing cere bral aneurysm, make up the initial section of the monograph.
Download or read book Cerebral Ischemia and Post Ischemic Treatment with Hypothermia written by Kym Campbell and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral Ischemia and Post-Ischemic Treatment with Hypothermia.
Download or read book The Effects of Moderate Hypothermia on IL 1beta and Ischemia induced Cerebral Inflammation in C57 Bl6 Mice written by Ian Sutcliffe and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypothermia has long been known to be neuroprotective following brain injury, yet the correlates of this neuroprotection are poorly understood. We postulated that moderate hypothermia would attenuate leukocyte rolling and adhesion following IL-1beta or cerebral ischemia induced inflammation. Laser Doppler was used to demonstrate successful induction of global cerebral ischemia in C57/B16 mice. ISEL, NeuN, and GFAP staining of brain sections were used to demonstrate temporal and spatial injury in this murine model of 10-minutes global cerebral ischemia. Four hours hypothermia (32°C) induced immediately following normothermic (37°C) cerebral ischemia provided protection against cell death and astrocytosis for up to 7 days post-ischemia. An open cranial window and intravital microscopy were used to visualize leukocyte rolling and adhesion in pial venules at 4-h following injection of IL-1beta, and 0 to 4-h following global cerebral ischemia. Increases in leukocyte rolling and adhesion were observed in IL-1beta injected mice. Four hours of hypothermia begun immediately following injection of IL-1beta reduced both rolling and adhesion. Similarly, increases in leukocyte rolling and adhesion were observed at 0-h and 2-h following cerebral ischemia in normothermic mice, and 2-h of post-ischemic hypothermia reduced both rolling and adhesion. In contrast, MPO and neutrophil immunohistochemistry showed that no significant infiltration of neutrophils into the brain following global cerebral ischemia. Molecular mechanisms of hypothermic effects were investigated in vitro. We showed that neither IL-1beta nor hypothermia altered the expression of CD18, or chemotaxis in human neutrophils. Together, these findings suggest that one mechanism by which hypothermia may provide neuroprotection is by reduction of leukocyte-endothelial interactions in the cerebromicrovasculature.
Download or read book Neuroprotective Therapy for Stroke and Ischemic Disease written by Paul A. Lapchak and published by Springer. This book was released on 2017-01-12 with total page 795 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical and comprehensive look at current state-of-the-art scientific and translational research being conducted internationally, in academia and industry, to address new ways to provide effective treatment to victims of ischemic and hemorrhagic stroke and other ischemic diseases. Currently stroke can be successfully treated through the administration of a thrombolytic, but the therapeutic window is short and many patients are not able to receive treatment. Only about 30% of patients are "cured" by available treatments. In 5 sections, the proposed volume will explore historical and novel neuroprotection mechanisms and targets, new and combination therapies, as well as clinical trial design for some of the recent bench-side research.
Download or read book Protracted Mild Hypothermia Provides Long term Histological and Behavioral Protection Following Global Cerebral Ischemia written by Frederick Colbourne and published by . This book was released on 1995 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Thermotherapy for Neoplasia Inflammation and Pain written by M. Kosaka and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the multitude of different forms of thermotherapy in connection with aspects of thermal physiology and cell biology. The aim is to elucidate the scientific background of therapeutic actions and to promote effective new applications at the beginning of the 21st century. Significant to these purposes is cooperation between experts in the fields of thermal biology, hyper thermic oncology, rheumatology, and balneology, as represented by the editors. Emphasis has been placed on a balanced choice of contributions, in the hope that this will enable the reader to draw helpful connections between the principles and prac tice of thermotherapy. It is apparent that a wealth of published data exists concerning thermotherapy on the one hand and thermal physiology on the other. However, in the former field empirical aspects of therapeutic usefulness prevail, while in the latter, aspects of basic science are in the foreground. Accordingly, the sources where published data may be found are quite different and as a consequence many findings of potential mutual interest published in medical journals have gone unnoticed by readers of physio logical journals, and vice versa. It is hoped that this book will bridge the gap and encourage researchers' efforts to integrate the available knowledge to attain optimal coordination of clinical and theoretical aspects.
Download or read book Effects of Hypothermia on Local Blood Flow and Metabolism During Cerebral Ischemia and Hypoxia written by John S. Meyer and published by . This book was released on 1957 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Brain Ischemia New Insights for the Healthcare Professional 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Ischemia: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Brain Ischemia in a concise format. The editors have built Brain Ischemia: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Brain Ischemia in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Brain Ischemia: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Hypothermia as an Alternative for the Management of Cerebral Ischemia written by Felipe Eduardo Nares-López and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypothermia as an Alternative for the Management of Cerebral Ischemia.
Download or read book Neurohospitalist Medicine written by S. Andrew Josephson and published by Cambridge University Press. This book was released on 2011-09-29 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, the hospitalist model has become a dominant system for the delivery of inpatient care. Forces such as national mandates to improve safety and quality, and intense pressure to safely reduce length of hospital stays, are now exerting pressure on neurologists. To meet these challenges, a new neurohospitalist model is emerging. This is the first authoritative text to detail the advances and strategies for treating neurologic disease in a hospital setting. It includes chapters on specific acute neurologic diseases including stroke, epilepsy, neuromuscular disease and traumatic brain injury and also addresses common reasons for neurologic consultation in the hospital including encephalopathy, electrolyte disturbances and neurologic complications of pregnancy. Ethical and structural issues commonly encountered in neurologic inpatients are also addressed. This will be a key resource for any clinician or trainee caring for neurologic patients in the hospital including practising neurologists, internists and trainees across multiple subspecialities.
