Download or read book Guidelines for the Clinical Management of Thalassaemia written by Maria-Domenica Cappellini and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hypertransfusion and Iron Chelation in Thalassaemia written by Muzaffer Aksoy and published by Hogrefe & Huber Publishing. This book was released on 1985 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Iron Overload and Chelation in Thalassaemia written by Christos Kattamis and published by H. Huber Publishing. This book was released on 1989 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Thalassemia An Issue of Hematology Oncology Clinics of North America E Book written by Ali Taher and published by Elsevier Health Sciences. This book was released on 2018-03-07 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics, edited by Dr. Ali Taher, focuses on Thalassemia. Topics include, but are not limited to, Molecular basis and genetic modifiers; Evolving spectrum of epidemiology; Clinical classification; Ineffective erythropoiesis, anemia and iron overload; Hypercoagulability and vascular disease; Clinical complications and their management; Transfusion and iron chelation therapy; Hematopoietic Stem Cell Transplantation in Thalassemia; Gene therapy and genome editing; Emerging therapies; Quality of life; Advances in understanding pathophysiology and treatment of fertility, pregnancy, and prenatal diagnosis in Thalassemia; and MRI for iron overload.
Download or read book The Effects of Desferrioxamine Iron Chelation Therapy in Hypertransfused Beta thalassemia Patients written by Gail Elizabeth Mizner and published by . This book was released on 1986 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hypertransfusion and Iron Chelation in Thalassaemia written by Muzaffer Aksoy and published by Hogrefe & Huber Publishing. This book was released on 1985 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Iron Chelation Therapy written by Chaim Hershko and published by Taylor & Francis US. This book was released on 2002 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the last few years, iron research has yielded exciting new insights into the understanding of normal iron homeostasis. Such development, and the evolution of improved strategies of Iron Chelating Therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant developments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload. This volume highlights the impact of long term Iron Celating Therapy using deferoxamine or the new, but controversial oral iron chelator deferiprone based on experience gained by multicenter trails, with special emphasis on survival, morbidity and drug toxicity; it reviews the development of the new and improved orally effective chelators suitable for clinical use in the near future and examines novel strategies of iron chelating treatment for the control of cell proliferation in malignant disease or malaria.
Download or read book Gene and Cell Therapies for Beta Globinopathies written by Punam Malik and published by Springer. This book was released on 2017-11-09 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemoglobin defects, specifically sickle cell disease & thalassemia, combined, constitute the most common monogenic disorders in the world. In fact, nearly 2% of the world’s population carries a globin gene mutation. The transfer of the corrective globin gene through the HSC compartment by allogeneic HSC transplantation (HSCT) has already proven curative in both SCD and thalassemia patients, and provides the proof of concept that genetic manipulation of the defective organ might be equally therapeutic. However, procedural toxicities and the requirement of an HLA-matched sibling donor limit this approach to a fraction of affected individuals. The editors review the progress & the state of the field in HSCT for hemoglobinopathies & shed light on the major changes expected in the next decade. Although allogeneic HSCT is a curative option, it is limited by the availability of matched donors, which are often available only to 15-20% of patients. An alternative to allogeneic HS CT is genetic correction of autologous HSCs, to overcome donor availability & immune side effects. This Book reviews the progress made on additive gene therapy approaches & the current state of the field. Finally, targeted genetic correction is emerging as a novel therapeutic strategy in the hemoglobinopathies. Although ideal, the inefficiency of targeted correction was rate limiting for translation of this technology to the clinic. With advancements in zinc finger nucleases and TALE endonuclease mediated targeted correction, correction frequencies in hematopoietic stem cells is now reaching levels that may become clinically relevant. Furthermore, the ability to generate autologous embryonic stem cell like cells from primary somatic cells (skin fibroblasts or hematopoietic cells) of the affected individual has allowed for the potential application of genetic correction strategies.This Book reviews upcoming genetic strategies to reactivate fetal hemoglobin production and research advances.
Download or read book Pediatric Hematology written by Robert Wynn and published by Cambridge University Press. This book was released on 2017-02-16 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: A succinct summary of the key principles and facts that guide the everyday practice of modern, clinical paediatric hematology. Covering all the information necessary for examinations in the topic, this book is ideal for postgraduates studying paediatric hematology, as well as for junior doctors in training.
Download or read book Chelation Therapy in Chronic Iron Overload written by Edward C. Zaino and published by . This book was released on 1977 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Red Cell Metabolism written by Ernest Beutler and published by . This book was released on 1975 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Beliefs in Iron Chelation Therapy Among Adult Transfusion Dependent Thalassemia Patients in University of Malaya Medical Center written by Norashikin Saidon and published by . This book was released on 2014 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hematology in the Adolescent Female written by Lakshmi V. Srivaths and published by Springer Nature. This book was released on 2020-08-11 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adolescent females experience a variety of blood disorders that are often unique to this patient population. As they go through puberty, they are uniquely poised to encounter various bleeding and thrombotic disorders once they attain menarche, start to have menstrual bleeding, and require hormonal therapy. This may in turn lead to other medical conditions, such as anemia and iron deficiency. Pregnancy encountered by some adolescents can pose hematologic challenges specifically in regards to bleeding and thrombotic disorders. In addition, adolescent females are at risk to develop immune mediated hematologic disorders, such as immune thrombocytopenia, auto-immune hemolytic anemia, and thrombotic thrombocytopenic purpura, as well as vitamin deficiencies due to pernicious anemia. Sickle cell disease, thalassemia and bone marrow failure disorders in the adolescent female poses unique challenges that need to be addressed with special care and attention. Knowledge about these various blood disorders in adolescent females is crucial for the treating physician in order to accurately diagnose and optimally manage these teenagers. Otherwise, it can affect their overall health, causing hematologic and gynecologic issues, poor quality of life, neurocognitive impairments, and poor psycho-social development, all of which can lead to various complications immediately and into adulthood. This book provides a comprehensive, state-of-the art overview of blood disorders in female adolescents. The text presents new data about bleeding disorders that affect the female adolescent, including bleeding disorders, thromboembolism, thrombophilia, anemia, sickle cell disease and thalassemia, disorders od hemostasis and thrombosis in pregnancy, immune hematology and bone marrow failure disorders; reviews our current understanding of these disorders; outlines recent research findings; and spotlights multi-disciplinary approaches, evaluation and treatment modalities to combat these blood disorders. Written by experts in the field, Hematology in the Adolescent Female is a valuable resource for clinicians and practitioners who treat and manage female adolescents with blood disorders.
Download or read book Textbook of Pediatric Hematology Hemato Oncology written by MR Lokeshwar and published by Jaypee Brothers Medical Publishers Pvt. Limited. This book was released on 2015-08-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook of Pediatric Hematology & Hemato-Oncology is a highly illustrated, comprehensive guide to diseases and cancers of the blood in paediatrics. Fifty chapters by internationally recognised paediatric haematologists and haemato-oncologists are grouped into seven sections, covering physiology, neonatal haematology, red blood cell and white blood cell disorders, bleeding disorders, transfusion medicine, haemato-oncology and other general topics. The haemato-oncology section covers cancers of the blood and includes lymphoblastic leukaemia, myeloid leukaemia (chronic and acute), juvenile myelomonocytic leukaemia, and bone marrow transplantation. The final ‘general’ section features discussion on gene therapy, monoclonal antibodies and biological response modifiers. Each chapter is peer-reviewed, with a list of references ensuring authoritative content, and the book is further enhanced by nearly 200 images and illustrations. Textbook of Pediatric Hematology & Hemato-Oncology is an indispensable resource for paediatricians, practitioners and trainees. Key Points Comprehensive guide to paediatric diseases and cancers of the blood 50 peer reviewed chapters with references 198 images and illustrations
Download or read book IAP Colour Atlas of Pediatrics written by A Parthasarathy and published by JP Medical Ltd. This book was released on 2012-04 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colour atlas pn paediatric illnesses and management covering both common and rare disorders.
Download or read book The Thalassemias written by D. J. Weatherall and published by . This book was released on 1983 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book European Handbook of Dermatological Treatments written by Andreas D. Katsambas and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 830 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dermatology is a specialty in the field of medicine which constantly changes at a vast rate. Alongside technology, new drugs, methods and treatments are continuously developed for the treatment of all common skin diseases. The first edition of the European Handbook of Dermatological Treatments received an overwhelming response from dermatovenereologists all over Europe. Its easy-to-read format, which is also used for this 2nd edition, is aimed at helping the physician to obtain comprehensive information at a glance. The three main sections listed alphabetically define the different diseases, the drugs available and the various methods of treatment used in dermatological practice. Each chapter begins with a brief section of the aetiology and pathogenesis of the skin disease, and leads into the description of the clinical characteristics, the diagnosis and the differential diagnosis. Followed by a detailed discussion on treatment methods, alternative methods are covered as well. Each section ends with a reference list for further reading. This new edition provides an excellent update including the newest developments of drugs, methods and treatments in dermatological practice, maintaining the clear structure and well-proven format. It is a very comprehensive and practical guide and should not be missed by those treating patients with skin diseases.
