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Book Biological  Physical and Technical Basics of Cell Engineering

Download or read book Biological Physical and Technical Basics of Cell Engineering written by Gerhard M. Artmann and published by Springer. This book was released on 2018-04-11 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents and discusses recent scientific progress on Cell and Stem Cell Engineering. It predominantly focuses on Biological, Physical and Technical Basics, and features new trends of research reaching far into the 21st century.

Book Finite Element Modeling of Soft Tissue Deformation

Download or read book Finite Element Modeling of Soft Tissue Deformation written by Hongjian Shi and published by . This book was released on 2007 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer-aided minimally invasive surgery (MIS) has progressed significantly in the last decade and it has great potential in surgical planning and operations. To limit the damage to nearby healthy tissue, accurate modeling is required of the mechanical behavior of a target soft tissue subject to surgical manipulations. Therefore, the study of soft tissue deformations is important for computer-aided (MIS) in surgical planning and operation, or in developing surgical simulation tools or systems. The image acquisition facilities are also important for prediction accuracy. This dissertation addresses partial differential and integral equations (PDIE) based biomechanical modeling of soft tissue deformations incorporating the specific material properties to characterize the soft tissue responses for certain human interface behaviors. To achieve accurate simulation of real tissue deformations, several biomechanical finite element (FE) models are proposed to characterize liver tissue. The contribution of this work is in theoretical and practical aspects of tissue modeling. High resolution imaging techniques of Micro Computed Tomography (Micro-CT) and Cone Beam Computed Tomography (CBCT) imaging are first proposed to study soft tissue deformation in this dissertation. These high resolution imaging techniques can detect the tissue deformation details in the contact region between the tissue and the probe for small force loads which would be applied to a surgical probe used. Traditional imaging techniques in clinics can only achieve low image resolutions. Very small force loads seen in these procedures can only yield tissue deformation on the few millimeters to sub-millimeter scale. Small variations are hardly to detect. Furthermore, if a model is validated using high resolution images, it implies that the model is true in using the same model for low resolution imaging facilities. The reverse cannot be true since the small variations at the sub-millimeter level cannot be detected. In this dissertation, liver tissue deformations, surface morphological changes, and volume variations are explored and compared from simulations and experiments. The contributions of the dissertation are as follows. For liver tissue, for small force loads (5 grams to tens of grams), the linear elastic model and the neo-Hooke's hyperelastic model are applied and shown to yield some discrepancies among them in simulations and discrepancies between simulations and experiments. The proposed finite element models are verified for liver tissue. A general FE modeling validation system is proposed to verify the applicability of FE models to the soft tissue deformation study. The validation of some FE models is performed visually and quantitatively in several ways in comparison with the actual experimental results. Comparisons among these models are also performed to show their advantages and disadvantages. The method or verification system can be applied for other soft tissues for the finite element analysis of the soft tissue deformation. For brain tissue, an elasticity based model was proposed previously employing local elasticity and Poisson's ratio. It is validated by intraoperative images to show more accurate prediction of brain deformation than the linear elastic model. FE analysis of brain ventricle shape changes was also performed to capture the dynamic variation of the ventricles in author's other works. There, for the safety reasons, the images for brain deformation modeling were from Magnetic Resonance Imaging (MRI) scanning which have been used for brain scanning. The measurement process of material properties involves the tissue desiccation, machine limits, human operation errors, and time factors. The acquired material parameters from measurement devices may have some difference from the tissue used in real state of experiments. Therefore, an experimental and simulation based method to inversely evaluate the material parameters is proposed and compared with the material parameters measured by devices. As known, the finite element method (FEM) is a comprehensive and accurate method used to solve the PDIE characterizing the soft tissue deformation in the three dimensional tissue domain, but the computational task is very large in implementation. To achieve near real time simulation and still a close solution of soft tissue deformation, region-of-interest (ROI) based sub-modeling is proposed and the accuracy of the simulated deformations are explored over concentric regions of interest. Such a ROI based FE modeling is compared to the FE modeling over the whole tissue and its efficiency is shown and as well as its influence in practical applications such as endoscopic surgical simulation.

Book Smoothed Finite Element Methods

Download or read book Smoothed Finite Element Methods written by G.R. Liu and published by CRC Press. This book was released on 2016-04-19 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Generating a quality finite element mesh is difficult and often very time-consuming. Mesh-free methods operations can also be complicated and quite costly in terms of computational effort and resources. Developed by the authors and their colleagues, the smoothed finite element method (S-FEM) only requires a triangular/tetrahedral mesh to achieve mo

Book Cartilage Tissue and Knee Joint Biomechanics

Download or read book Cartilage Tissue and Knee Joint Biomechanics written by Amirsadegh Rezazadeh Nochehdehi and published by Elsevier. This book was released on 2023-09-18 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cartilage, Tissue and Knee Joint Biomechanics: Fundamentals, Characterization and Modelling is a cutting-edge multidisciplinary book specifically focused on modeling, characterization and related clinical aspects. The book takes a comprehensive approach towards mechanics, fundamentals, morphology and properties of Cartilage Tissue and Knee Joints. Leading researchers from health science, medical technologists, engineers, academics, government, and private research institutions across the globe have contributed to this book. This book is a very valuable resource for graduates and postgraduates, engineers and research scholars. The content also includes comprehensive real-world applications. As a reference for the total knee arthroplasty, this book focuses deeply on existing related theories (including: histology, design, manufacturing and clinical aspects) to assist readers in solving fundamental and applied problems in biomechanical and biomaterials characterization, modeling and simulation of human cartilages and cells. For biomedical engineers dealing with implants and biomaterials for knee joint injuries, this book will guide you in learning the knee anatomy, range of motion, surgical procedures, physiological loading and boundary conditions, biomechanics of connective soft tissues, type of injuries, and more. Provides a comprehensive resource on the knee joint and its connective soft tissues; content included spans biomechanics, biomaterials, biology, anatomy, imaging and surgical procedure Covers ISO and FDA based regulatory control and compliance in the manufacturing process Includes discussions on the relationship between knee anatomical parameters and knee biomechanics

Book Crystal Plasticity Finite Element Methods

Download or read book Crystal Plasticity Finite Element Methods written by Franz Roters and published by John Wiley & Sons. This book was released on 2011-08-04 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the leading experts in computational materials science, this handy reference concisely reviews the most important aspects of plasticity modeling: constitutive laws, phase transformations, texture methods, continuum approaches and damage mechanisms. As a result, it provides the knowledge needed to avoid failures in critical systems udner mechanical load. With its various application examples to micro- and macrostructure mechanics, this is an invaluable resource for mechanical engineers as well as for researchers wanting to improve on this method and extend its outreach.

Book Biomechanical Models for Soft Tissue Simulation

Download or read book Biomechanical Models for Soft Tissue Simulation written by Walter Maurel and published by Springer Science & Business Media. This book was released on 2013-11-22 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of biomechanical modeling of human soft tissue using nonlinear theoretical mechanics and incremental finite element methods, useful for computer simulation of the human musculoskeletal system.

Book Continuum Theory of the Mechanics of Fibre Reinforced Composites

Download or read book Continuum Theory of the Mechanics of Fibre Reinforced Composites written by A.J.M. Spencer and published by Springer. This book was released on 2014-05-04 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Automated Solution of Differential Equations by the Finite Element Method

Download or read book Automated Solution of Differential Equations by the Finite Element Method written by Anders Logg and published by Springer Science & Business Media. This book was released on 2012-02-24 with total page 723 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a tutorial written by researchers and developers behind the FEniCS Project and explores an advanced, expressive approach to the development of mathematical software. The presentation spans mathematical background, software design and the use of FEniCS in applications. Theoretical aspects are complemented with computer code which is available as free/open source software. The book begins with a special introductory tutorial for beginners. Following are chapters in Part I addressing fundamental aspects of the approach to automating the creation of finite element solvers. Chapters in Part II address the design and implementation of the FEnicS software. Chapters in Part III present the application of FEniCS to a wide range of applications, including fluid flow, solid mechanics, electromagnetics and geophysics.

Book Material Modeling in Finite Element Analysis

Download or read book Material Modeling in Finite Element Analysis written by Zhaochun Yang and published by CRC Press. This book was released on 2019-10-10 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finite element analysis has been widely applied in mechanical, civil, and biomedical designs. This book aims to provide the readers comprehensive views of various material models with practical examples, which would help readers understand various materials, and build appropriate material models in the finite element analysis. This book is composed of four main parts: 1) metals, 2) polymers, 3) soils, and 4) modern materials. Each part starts with the structure and function of different materials and then follows the corresponding material models such as BISO, MISO, Chaboche model in metals, Arruda-Boyce model, Mooney-Rivlin model, Ogden model in polymers, Mohr-Coulomb model, Cam Clay model and Jointed Rock model in geomechanics, composites and shape memory alloys in modern materials. The final section presents some specific problems, such as metal forming process, combustion chamber, Mullins effect of rubber tire, breast shape after breast surgery, viscoelasticity of liver soft tissues, tunnel excavation, slope stability, orthodontic wire, and piezoelectric microaccelerometer. All modeling files are provided in the appendixes of the book. This book would be helpful for graduate students and researchers in the mechanical, civil, and biomedical fields who conduct finite element analysis. The book provides all readers with comprehensive understanding of modeling various materials.

Book Nonlinear Continuum Mechanics for Finite Element Analysis

Download or read book Nonlinear Continuum Mechanics for Finite Element Analysis written by Javier Bonet and published by Cambridge University Press. This book was released on 1997-09-28 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unified treatment of nonlinear continuum analysis and finite element techniques.

Book Nonlinear Finite Element Analysis of Solids and Structures

Download or read book Nonlinear Finite Element Analysis of Solids and Structures written by René de Borst and published by John Wiley & Sons. This book was released on 2012-07-25 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Built upon the two original books by Mike Crisfield and their own lecture notes, renowned scientist René de Borst and his team offer a thoroughly updated yet condensed edition that retains and builds upon the excellent reputation and appeal amongst students and engineers alike for which Crisfield's first edition is acclaimed. Together with numerous additions and updates, the new authors have retained the core content of the original publication, while bringing an improved focus on new developments and ideas. This edition offers the latest insights in non-linear finite element technology, including non-linear solution strategies, computational plasticity, damage mechanics, time-dependent effects, hyperelasticity and large-strain elasto-plasticity. The authors' integrated and consistent style and unrivalled engineering approach assures this book's unique position within the computational mechanics literature. Key features: Combines the two previous volumes into one heavily revised text with obsolete material removed, an improved layout and updated references and notations Extensive new material on more recent developments in computational mechanics Easily readable, engineering oriented, with no more details in the main text than necessary to understand the concepts. Pseudo-code throughout makes the link between theory and algorithms, and the actual implementation. Accompanied by a website (www.wiley.com/go/deborst) with a Python code, based on the pseudo-code within the book and suitable for solving small-size problems. Non-linear Finite Element Analysis of Solids and Structures, 2nd Edition is an essential reference for practising engineers and researchers that can also be used as a text for undergraduate and graduate students within computational mechanics.

Book Biomechanics of Soft Tissues

Download or read book Biomechanics of Soft Tissues written by Adil Al Mayah and published by CRC Press. This book was released on 2018-02-21 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emerging paradigm of incorporating images and biomechanical properties of soft tissues has proven to be an integral part of the advancement of several medical applications, including image guided radiotherapy and surgery, brachytherapy, and diagnostics. This expansion has resulted in a growing community of medical, science, and engineering professionals applying mechanical principles to address medical concerns. This book is tailored to cover a range of mechanical principles, properties, and applications of soft tissues that have previously been addressed in various journals and "anatomical site-specific" books. Biomechanics of Soft Tissues follows a different approach by offering a simplified overview of widely used mechanical models and measuring techniques of soft tissue parameters. This is followed by an investigation of different medical applications, including: biomechanical aspects of cancerous tumor progressions, radiotherapy treatment, and image guided ultrasound guided interventions. Written by leading scholars and professionals in the field, Biomechanics of Soft Tissues combines engineering and medical expertise, thereby producing an excellent source of information for professionals interested in the theoretical and technological advancements related to soft tissues. The book provides medical professionals with an insight on various modeling approaches, testing techniques, and mechanical characteristics that are frequently used by engineers. Conversely, the presented medical applications provide engineers with a glimpse of amazing medical practices and encourage them to expand their roles in the medical field. Provides a simplified overview of mechanics of soft tissues. Highlights different techniques to measure tissues properties for engineering and medical applications. Contains novel ideas to address roles of mechanics in disease progression and treatment. Presents innovative applications of biomechanics in medical procedures.

Book Computational Contact Mechanics

Download or read book Computational Contact Mechanics written by Peter Wriggers and published by Springer Science & Business Media. This book was released on 2008-04-01 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topics of this book span the range from spatial and temporal discretization techniques for contact and impact problems with small and finite deformations over investigations on the reliability of micromechanical contact models over emerging techniques for rolling contact mechanics to homogenization methods and multi-scale approaches in contact problems.

Book Computational Methods for Plasticity

Download or read book Computational Methods for Plasticity written by Eduardo A. de Souza Neto and published by John Wiley & Sons. This book was released on 2011-09-21 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject of computational plasticity encapsulates the numerical methods used for the finite element simulation of the behaviour of a wide range of engineering materials considered to be plastic – i.e. those that undergo a permanent change of shape in response to an applied force. Computational Methods for Plasticity: Theory and Applications describes the theory of the associated numerical methods for the simulation of a wide range of plastic engineering materials; from the simplest infinitesimal plasticity theory to more complex damage mechanics and finite strain crystal plasticity models. It is split into three parts - basic concepts, small strains and large strains. Beginning with elementary theory and progressing to advanced, complex theory and computer implementation, it is suitable for use at both introductory and advanced levels. The book: Offers a self-contained text that allows the reader to learn computational plasticity theory and its implementation from one volume. Includes many numerical examples that illustrate the application of the methodologies described. Provides introductory material on related disciplines and procedures such as tensor analysis, continuum mechanics and finite elements for non-linear solid mechanics. Is accompanied by purpose-developed finite element software that illustrates many of the techniques discussed in the text, downloadable from the book’s companion website. This comprehensive text will appeal to postgraduate and graduate students of civil, mechanical, aerospace and materials engineering as well as applied mathematics and courses with computational mechanics components. It will also be of interest to research engineers, scientists and software developers working in the field of computational solid mechanics.

Book Finite Element Analysis Concepts

Download or read book Finite Element Analysis Concepts written by J. E. Akin and published by World Scientific. This book was released on 2010 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Young engineers are often required to utilize commercial finite element software without having had a course on finite element theory. That can lead to computer-aided design errors. This book outlines the basic theory, with a minimum of mathematics, and how its phases are structured within a typical software. The importance of estimating a solution, or verifying the results, by other means is emphasized and illustrated. The book also demonstrates the common processes for utilizing the typical graphical icon interfaces in commercial codes. in particular, the book uses and covers the widely utilized SolidWorks solid modeling and simulation system to demonstrate applications in heat transfer, stress analysis, vibrations, buckling, and other fields. The book, with its detailed applications, will appeal to upper-level undergraduates as well as engineers new to industry.

Book An Introduction to Meshfree Methods and Their Programming

Download or read book An Introduction to Meshfree Methods and Their Programming written by G.R. Liu and published by Springer Science & Business Media. This book was released on 2005-12-05 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: The finite difference method (FDM) hasbeen used tosolve differential equation systems for centuries. The FDM works well for problems of simple geometry and was widely used before the invention of the much more efficient, robust finite element method (FEM). FEM is now widely used in handling problems with complex geometry. Currently, we are using and developing even more powerful numerical techniques aiming to obtain more accurate approximate solutions in a more convenient manner for even more complex systems. The meshfree or meshless method is one such phenomenal development in the past decade, and is the subject of this book. There are many MFree methods proposed so far for different applications. Currently, three monographs on MFree methods have been published. Mesh Free Methods, Moving Beyond the Finite Element Method d by GR Liu (2002) provides a systematic discussion on basic theories, fundamentals for MFree methods, especially on MFree weak-form methods. It provides a comprehensive record of well-known MFree methods and the wide coverage of applications of MFree methods to problems of solids mechanics (solids, beams, plates, shells, etc.) as well as fluid mechanics. The Meshless Local Petrov-Galerkin (MLPG) Method d by Atluri and Shen (2002) provides detailed discussions of the meshfree local Petrov-Galerkin (MLPG) method and itsvariations. Formulations and applications of MLPG are well addressed in their book.