Download or read book Hydroxy Pyridones as Antifungal Agents with Special Emphasis on Onychomycosis written by Sam Shuster and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the results of two symposia held on hydroxy-pyridones as antifungal agents organized on the occasion of the International Summit on Cutaneous Antifungal Therapy 1996 in Vancouver and the 19th World Congress of Dermatology 1997 in Sydney. Some of the papers deal with the basic mechanisms of action and how these translate into product features, e.g. activity spectrum. Other papers describe the unique properties of hydroxy-pyridones, such as high penetration into and through keratinic tissues or their activity as dual inhibitor on 5-lipoxygenase and cyclooxygenase which leads to a remarkable antiinflammatory effect. Last but not least various accounts are given which show how this unique product profile aids the treatment of various fungal diseases, especially onychomycosis.

Download or read book Pyridine and Its Derivatives Volume 14 Part 3 written by Erwin Klingsberg and published by John Wiley & Sons. This book was released on 2009-09-15 with total page 927 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Download or read book Biotic Type Antioxidants the prospective search area for novel chemical drugs written by E A. Parfenov and published by Routledge. This book was released on 2018-12-19 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of molecular and cellular mechanisms of pathology, together with the present data on drug treatment result in enhanced drug design and testing. The known mechanisms of biological activity as displayed by ascorbic acid and other natural reductones are the reason that they are considered to be physiologically compatible antioxidants, many of which are trace elements in food. The pharmacological potential of natural antioxidants may be enhanced by chemical modification. Biotic antioxidants possess an important potential to be a reliable basis of the development of new multipurpose drugs, within the framework of existing technological structures. This book shows approaches for possible use of these natural antioxidants. In particular, such an approach is described for the case of the design of superoxide dismutase models with anti-tumour activity.

Download or read book Pyridine and Its Derivatives Volume 14 Part 2 written by Erwin Klingsberg and published by John Wiley & Sons. This book was released on 2009-09-15 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Download or read book Iron and Human Disease written by R.B. Lauffer and published by CRC Press. This book was released on 2018-01-18 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron and Human Disease is the first book to cover the three key aspects of human iron metabolism: the accumulation of iron in adults, iron as a limiting factor for tumor and infectious cell growth, and iron as a catalyst for oxygen free radical production. The book describes the hypotheses and findings related to the role of iron in cardiovascular disease (including reperfusion injury), cancer, aging, and autoimmune and neurodegenerative diseases. Other topics covered include the molecular biology and biochemistry of iron, the general principles governing iron balance, iron in the immune system and acute phase response, and new preventive and therapeutic strategies. Iron and Human Disease will be a useful reference for biomedical investigators, physicians, nutritionists, and public health officials.

Download or read book The Development of Iron Chelators for Clinical Use written by Raymond J. Bergeron and published by CRC Press. This book was released on 1993-12-06 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Representing an integration of basic and clinical sciences, this book focuses on new concepts in the design, synthesis, and testing of iron chelators for clinical application. It provides an overview of the pathophysiology of iron metabolism as it relates to the origins of iron-mediated tissue damage, and it clearly outlines successes and shortcomings of current iron chelation therapy in preventing such damage. The book also describes a number of other exciting potential therapeutic applications of iron chelators, such as in the treatment of malaria. Other topics covered include iron coordination chemistry, recent advances in synthetic methods for accessing iron chelators, siderophore models, subcellular iron storage targets, and the possible application of biotechnology in the production of therapeutically useful iron chelators. The book also describes new animal models for evaluating chelators.

Download or read book Comprehensive Organic Synthesis written by and published by Newnes. This book was released on 2014-02-14 with total page 9815 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition, Nine Volume Set an invaluable source, providing an authoritative overview of core concepts. Winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers Contains more than170 articles across nine volumes, including detailed analysis of core topics such as bonds, oxidation, and reduction Includes more than10,000 schemes and images Fully revised and updated; important growth areas—including combinatorial chemistry, new technological, industrial, and green chemistry developments—are covered extensively

Download or read book Domino Reactions in Organic Synthesis written by Lutz F. Tietze and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: Domino reactions enable you to build complex structures in one-pot reactions without the need to isolate intermediates- a dream comes true. In this book, the well-respected expert, Professor Lutz Tietze, summarizes the possibilities of this reaction type - an approach for an efficiant, economically benificial and ecological benign synthesis. A definite must for every organic chemist.

Download or read book Advances in Heterocyclic Chemistry written by and published by Academic Press. This book was released on 1963-01-01 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Heterocyclic Chemistry

Download or read book Chemical Abstracts written by and published by . This book was released on 1912 with total page 1648 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Official Gazette of the United States Patent and Trademark Office written by and published by . This book was released on 1992 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pyridine and Its Derivatives written by and published by . This book was released on 1960 with total page 932 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pyridine and Its Derivatives written by Erwin Klingsberg and published by . This book was released on 1961 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt:

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Download or read book Kucers The Use of Antibiotics Sixth Edition written by M Lindsay Grayson and published by CRC Press. This book was released on 2010-10-29 with total page 3211 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics

Download or read book Toxicology and Industrial Health written by and published by . This book was released on 1993 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Antioxidants written by American Health Foundation and published by . This book was released on 1993 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: