Download or read book Hunting Down Huntington s written by Molly Kay Moss and published by FriesenPress. This book was released on 2019-12-17 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: My book is targeted towards any individual who has been affected by Huntington Disease, professionals and families, patients and their caregivers. The key theme is the devastation caused by this rare and fatal diabolical disease, it describes the wider circle affected when this disease strikes and how various persons handle the news. Hunting down Huntington's also presents strategies that are beneficial in navigating through this disease process. The book aims to increase the awareness of this disorder and inform the reader of its origins, history and on going research. I would like the reader to take away. . new knowledge of the HD process . learn about the ongoing research . become involved in the larger HD community chapters . learn ways where they can contribute . have a greater awareness of this condition My book's objective is to raise awareness for this illness and to encourage people to become involved in the local chapters. My desire is to give hope and encouragement to affected families. I'm also directing all royalties from the book to THE HUNTINGTON'S SOCIETY OF CANADA. Reading and learning about neurological diseases is significant because it's already believed that if a cure is found for HD other neurological dementias could also be prevented. My book isn't a supplement for business or a course.

Download or read book Food for Huntington s Disease written by M. Mohamed Essa and published by . This book was released on 2018 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food and Huntington's Disease is another book in a series of books related to the benefits of food on brain function. This book designates the possible beneficial effects of edible natural products and their active materials on Huntington's disease. This is a progressive neurodegenerative disease that could cause uncontrolled movements, cognitive difficulties and emotional disturbances. The aim of this book and its series is to create awareness in general audiences about the dietary perception to reduce the occurrence of Huntington's disease. This may enable a better understanding and possibly reduce the cost on medical bills for patients (approximately $4500/year/person) and the insurance companies. Literature revealed that this disturbing neurodegenerative disorder has a higher prevalence in Europe (3-7 in 100,000), North America (4-5 in 100,000), and Australia than in Asian countries. Studies suggest that mutation in the HD gene and the repeat expansion play an important role in the pathophysiology of this disease. The genetic defect underlying Huntington's disease is unstable, caused by an abnormal CAG expansion within the first exon of the Huntingtin gene (HTT), leading to an expanded polyglutamine (polyQ) track in the HTT protein. This disease is an inherited one. Even though the prevalence rate is moderate, scientists predict that a lot of people possess the possibility of carrying this disease. Mitochondrial dysfunction and oxidative stress could very highly play a role in this disease. In the last decade, the benefits of food on many diseases - including brain diseases - were explored. This book aims to summarize the recent updates on the benefit of natural edible materials and their active principles on the prevention or delaying of the progression or the management of this disease. The editors feel highly obligated to all the contributors for this initiative. Undeniably, they believe that the information provided in this book would raise the awareness of the readers and could possibly help them to understand the disease process and the benefits of food items on Huntington's' disease management.

Download or read book Huntington s Disease written by Stephanie E. Clipper and published by . This book was released on 1998 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biomarkers for Huntington s Disease written by Elizabeth A. Thomas and published by Springer Nature. This book was released on 2023-11-13 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Huntington’s disease (HD) is a fatal, inherited, neurodegenerative disorder, characterized by chorea, motor instabilities, psychiatric manifestations and cognitive decline. Early genetic testing provides an opportunity for clinical interventions aimed at delaying onset and/or slowing progression of disease; however, current treatments for HD are limited, with only two FDA-approved drugs available to manage chorea. Encouragingly, however, several disease-modifying treatment approaches are in the therapeutic pipeline, with more than 200 clinical studies, and many more preclinical studies, in the works. Robust and reliable biomarkers are needed to predict disease onset, monitor disease progression and assess treatment responses. More specifically, biomarkers to stratify patients for clinical trials and biomarkers to track drug efficacy will certainly lead to improved clinical trial design and success. This book represents the first book focused solely on biomarkers for HD and represents a distinct resource that will be informative, not only for clinicians and those involved in clinical trial design, but also for a wide range of neurodegenerative disease researchers. This edited volume is written by top leaders in the field, and takes a cross-disciplinary approach to cover a broad spectrum of biomarker types, in order to provide the latest advances in the development of biochemical, molecular, imaging and digital biomarkers that have been investigated for HD. With the ultimate goal of treating patients, the development of disease-associated biomarkers has never been more important.

Download or read book Huntington s Disease New Insights for the Healthcare Professional 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-10 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Huntington's Disease: New Insights for the Healthcare Professional: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Huntington Disease. The editors have built Huntington's Disease: New Insights for the Healthcare Professional: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Huntington Disease in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Huntington's Disease: New Insights for the Healthcare Professional: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book The Neuropathology of Huntington s Disease Classical Findings Recent Developments and Correlation to Functional Neuroanatomy written by Udo Rüb and published by Springer. This book was released on 2015-09-29 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correlating neuropathological data with results on the functional neuroanatomy of the human brain, subsequent chapters will highlight recent HD findings: the neuronal loss in the cerebral neo-and allocortex, the neurodegeneration of select thalamic nuclei, the affection of the cerebellar cortex and nuclei, the involvement of select brainstem nuclei, as well as the pathophysiological relevance of these pathologies for the clinical picture of HD. Finally, the potential pathophysiological role of neuronal huntingtin aggregations and the most important and enduring challenges of neuropathological HD research are discussed.

Download or read book Genetic Twists of Fate written by Stanley Fields and published by MIT Press. This book was released on 2013-02-08 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: How tiny variations in our personal DNA can determine how we look, how we behave, how we get sick, and how we get well. News stories report almost daily on the remarkable progress scientists are making in unraveling the genetic basis of disease and behavior. Meanwhile, new technologies are rapidly reducing the cost of reading someone's personal DNA (all six billion letters of it). Within the next ten years, hospitals may present parents with their newborn's complete DNA code along with her footprints and APGAR score. In Genetic Twists of Fate, distinguished geneticists Stanley Fields and Mark Johnston help us make sense of the genetic revolution that is upon us. Fields and Johnston tell real life stories that hinge on the inheritance of one tiny change rather than another in an individual's DNA: a mother wrongly accused of poisoning her young son when the true killer was a genetic disorder; the screen siren who could no longer remember her lines because of Alzheimer's disease; and the president who was treated with rat poison to prevent another heart attack. In an engaging and accessible style, Fields and Johnston explain what our personal DNA code is, how a few differences in its long list of DNA letters makes each of us unique, and how that code influences our appearance, our behavior, and our risk for such common diseases as diabetes or cancer.

Download or read book Bioethics written by Helga Kuhse and published by John Wiley & Sons. This book was released on 2015-12-21 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now fully revised and updated, Bioethics: An Anthology, 3rd edition, contains a wealth of new material reflecting the latest developments. This definitive text brings together writings on an unparalleled range of key ethical issues, compellingly presented by internationally renowned scholars. The latest edition of this definitive one-volume collection, now updated to reflect the latest developments in the field Includes several new additions, including important historical readings and new contemporary material published since the release of the last edition in 2006 Thematically organized around an unparalleled range of issues, including discussion of the moral status of embryos and fetuses, new genetics, neuroethics, life and death, resource allocation, organ donations, public health, AIDS, human and animal experimentation, genetic screening, and issues facing nurses Subjects are clearly and captivatingly discussed by globally distinguished bioethicists A detailed index allows the reader to find terms and topics not listed in the titles of the essays themselves

Download or read book Biology of the NMDA Receptor written by Antonius M. VanDongen and published by CRC Press. This book was released on 2008-10-29 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written

Download or read book Technology and Values written by Craig Hanks and published by John Wiley & Sons. This book was released on 2009-05-04 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: This anthology features essays and book excerpts on technology and values written by preeminent figures in the field from the early 20th century to the present. It offers an in-depth range of readings on important applied issues in technology as well. Useful in addressing questions on philosophy, sociology, and theory of technology Includes wide-ranging coverage on metaphysics, ethics, and politics, as well as issues relating to gender, biotechnology, everyday artifacts, and architecture A good supplemental text for courses on moral or political problems in which contemporary technology is a unit of focus An accessible and thought-provoking book for beginning and advanced undergraduates; yet also a helpful resource for graduate students and academics

Download or read book Shadows on the Koyukuk written by Jim Rearden and published by Graphic Arts Books. This book was released on 2014-04-04 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: “I owe Alaska. It gave me everything I have.” Says Sidney Huntington, son of an Athapaskan mother and white trader/trapper father. Growing up on the Koyukuk River in Alaska’s harsh Interior, that “everything” spans 78 years of tragedies and adventures. When his mother died suddenly, 5-year-old Huntington protected and cared for his younger brother and sister during two weeks of isolation. Later, as a teenager, he plied the wilderness traplines with his father, nearly freezing to death several times. One spring, he watched an ice-filled breakup flood sweep his family’s cabin and belongings away. These and many other episodes are the compelling background for the story of a man who learned the lessons of a land and culture, lessons that enabled him to prosper as trapper, boat builder, and fisherman. This is more than one man's incredible tale of hardship and success in Alaska. It is also a tribute to the Athapaskan traditions and spiritual beliefs that enabled him and his ancestors to survive. His story, simply told, is a testament to the durability of Alaska's wild lands and to the strength of the people who inhabit them.

Download or read book Encyclopedia of Neuroscience Volume 1 written by Larry R. Squire and published by Academic Press. This book was released on 2009-06-12 with total page 12505 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of the Neuroscience explores all areas of the discipline in its focused entries on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. Each article is written by an expert in that specific domain and peer reviewed by the advisory board before acceptance into the encyclopedia. Each article contains a glossary, introduction, a reference section, and cross-references to other related encyclopedia articles. Written at a level suitable for university undergraduates, the breadth and depth of coverage will appeal beyond undergraduates to professionals and academics in related fields.

Download or read book The Third Wave written by Samuel P. Huntington and published by University of Oklahoma Press. This book was released on 2012-09-06 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Between 1974 and 1990 more than thirty countries in southern Europe, Latin America, East Asia, and Eastern Europe shifted from authoritarian to democratic systems of government. This global democratic revolution is probably the most important political trend in the late twentieth century. In The Third Wave, Samuel P. Huntington analyzes the causes and nature of these democratic transitions, evaluates the prospects for stability of the new democracies, and explores the possibility of more countries becoming democratic. The recent transitions, he argues, are the third major wave of democratization in the modem world. Each of the two previous waves was followed by a reverse wave in which some countries shifted back to authoritarian government. Using concrete examples, empirical evidence, and insightful analysis, Huntington provides neither a theory nor a history of the third wave, but an explanation of why and how it occurred. Factors responsible for the democratic trend include the legitimacy dilemmas of authoritarian regimes; economic and social development; the changed role of the Catholic Church; the impact of the United States, the European Community, and the Soviet Union; and the "snowballing" phenomenon: change in one country stimulating change in others. Five key elite groups within and outside the nondemocratic regime played roles in shaping the various ways democratization occurred. Compromise was key to all democratizations, and elections and nonviolent tactics also were central. New democracies must deal with the "torturer problem" and the "praetorian problem" and attempt to develop democratic values and processes. Disillusionment with democracy, Huntington argues, is necessary to consolidating democracy. He concludes the book with an analysis of the political, economic, and cultural factors that will decide whether or not the third wave continues. Several "Guidelines for Democratizers" offer specific, practical suggestions for initiating and carrying out reform. Huntington's emphasis on practical application makes this book a valuable tool for anyone engaged in the democratization process. At this volatile time in history, Huntington's assessment of the processes of democratization is indispensable to understanding the future of democracy in the world.

Download or read book Faces of Huntington s written by Carmen Leal-Pock and published by Belleville, Ont. : Essence Pub.. This book was released on 1998 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Bioethics written by Udo Schüklenk and published by John Wiley & Sons. This book was released on 2021-09-08 with total page 948 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of the classic collection of key readings in bioethics, fully updated to reflect the latest developments and main issues in the field For more than two decades, Bioethics: An Anthology has been widely regarded as the definitive single-volume compendium of seminal readings on both traditional and cutting-edge ethical issues in biology and medicine. Acclaimed for its scope and depth of coverage, this landmark work brings together compelling writings by internationally-renowned bioethicist to help readers develop a thorough understanding of the central ideas, critical issues, and current debate in the field. Now fully revised and updated, the fourth edition contains a wealth of new content on ethical questions and controversies related to the COVID-19 pandemic, advances in CRISPR gene editing technology, physician-assisted death, public health and vaccinations, transgender children, medical aid in dying, the morality of ending the lives of newborns, and much more. Throughout the new edition, carefully selected essays explore a wide range of topics and offer diverse perspectives that underscore the interdisciplinary nature of bioethical study. Edited by two of the field’s most respected scholars, Bioethics: An Anthology: Covers an unparalleled range of thematically-organized topics in a single volume Discusses recent high-profile cases, debates, and ethical issues Features three brand-new sections: Conscientious Objection, Academic Freedom and Research, and Disability Contains new essays on topics such as brain death, life and death decisions for the critically ill, experiments on humans and animals, neuroethics, and the use of drugs to ease the pain of unrequited love Includes a detailed index that allows the reader to easily find terms and topics of interest Bioethics: An Anthology, Fourth Edition remains a must-have resource for all students, lecturers, and researchers studying the ethical implications of the health-related life sciences, and an invaluable reference for doctors, nurses, and other professionals working in health care and the biomedical sciences.

Download or read book Huntington s Disease written by Oliver Quarrell and published by Oxford University Press. This book was released on 2008-02-28 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Huntington's disease affects 1 person in 10,000 but this figure is an underestimate because the immediate carer, spouse/partner and the close relatives at risk of developing this condition in the future are also affected. The new edition has been revised to include important new developments that have occurred in the field in recent years.

Download or read book Huntington s Disease New Insights for the Healthcare Professional 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Huntington’s Disease: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Additional Research. The editors have built Huntington’s Disease: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Huntington’s Disease: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.