Download or read book Human Targets written by Victor M. Rios and published by University of Chicago Press. This book was released on 2017-03-08 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Victor Rios has a vibrant reputation as America s leading ethnographer of Latino youth. His personal storygoing from drug pusher (selling heroin on the streets as a teenager) to a hard worker at a mechanic shop within a matter of weeksshows how he stands in the place of the Latino youths he studies. His story underscores the degree to which delinquent urban youths can become adaptable, fluid, amenable individuals, able to shift their views of the world as well as their actions. Rios rejects the old storyline that said gangs are bad and they do bad things because they are bad people. Kids on the street, he argues, can drift between different identities, indeed, they can shift seamlessly between responsible and deviant displays within a few hours time. The key to understanding gang-associated youth lies in analysis of the way authority figures (teachers and police officers) interact with young people. The kids need caring adults who offer tangible resources. Story and characters are always front-and-center in Rios s narrative: Jorge, Mark, Wilson, and others, are boys we get to know as they negotiate day-to-day life on the streets and across institutional settings. We learn a great deal about Cholo subculture, the clothing and hairstyles, and the argot that are adopted by Latino youth in response to the forces that seek to marginalize or punish them. The crisis of a perceived epidemic of police brutality in our post-Ferguson era is a product of culture in Rios s view: contested symbols, negative interactions, and day-to-day encounters that freeze youth identities as gang-associated, and that freeze authority identities as negative shapers of youth attitudes and actions are the dynamic. Fear of young males of color leads to police misreading and dehumanizing of young black and Latino men. Rios raises our awareness of how this dynamic operates by studying his subjects whole: following young gang members into their schools, their homes, their community organizations, their detention facilities, and watching them interact with police, watching them grow up to become fathers, get jobs, get rap sheets. Get killed. This book will be a landmark contribution to the social psychology of poverty and crime."
Download or read book Human Targets written by Victor M. Rios and published by University of Chicago Press. This book was released on 2017-03-10 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: At fifteen, Victor Rios found himself a human target—flat on his ass amid a hail of shotgun fire, desperate for money and a place on the street. Faced with the choice of escalating a drug turf war or eking out a living elsewhere, he turned to a teacher, who mentored him and helped him find a job at an auto shop. That job would alter the course of his whole life—putting him on the road to college and eventually a PhD. Now, Rios is a rising star, hailed for his work studying the lives of African American and Latino youth. In Human Targets, Rios takes us to the streets of California, where we encounter young men who find themselves in much the same situation as fifteen-year-old Victor. We follow young gang members into schools, homes, community organizations, and detention facilities, watch them interact with police, grow up to become fathers, get jobs, get rap sheets—and in some cases get killed. What is it that sets apart young people like Rios who succeed and survive from the ones who don’t? Rios makes a powerful case that the traditional good kid/bad kid, street kid/decent kid dichotomy is much too simplistic, arguing instead that authorities and institutions help create these identities—and that they can play an instrumental role in providing young people with the resources for shifting between roles. In Rios’s account, to be a poor Latino youth is to be a human target—victimized and considered an enemy by others, viewed as a threat to law enforcement and schools, and burdened by stigma, disrepute, and punishment. That has to change. This is not another sensationalistic account of gang bangers. Instead, the book is a powerful look at how authority figures succeed—and fail—at seeing the multi-faceted identities of at-risk youths, youths who succeed—and fail—at demonstrating to the system that they are ready to change their lives. In our post-Ferguson era, Human Targets is essential reading.
Download or read book Necessary Targets written by Eve Ensler and published by Dramatists Play Service Inc. This book was released on 2003 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE STORY: In NECESSARY TARGETS, two American women, a Park Avenue psychiatrist and an ambitious young writer, travel to Bosnia to help women refugees confront their memories of war. Though the two have little in common beyond the methods they use
Download or read book Human Drug Targets written by Edward D. Zanders and published by John Wiley & Sons. This book was released on 2015-12-14 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The identification of drug targets in a given disease has been central to pharmaceutical research from the latter half of the 20th century right up to the modern genomics era. Human Drug Targets provides an essential guide to one of the most important aspects of drug discovery – the identification of suitable protein and RNA targets prior to the creation of drug development candidates. The first part of the book consists of introductory chapters that provide the background to drug target discovery and highlight the way in which these targets have been organised into online databases. It also includes a user’s guide to the list of entries that forms the bulk of the book. Since this is not designed to be a compendium of drugs, the emphasis will be on the known (or speculated) biological role of the targets and not on the issues associated with pharmaceutical development. The objective is to provide just enough information to be informative and prompt further searches, while keeping the amount of text for each of the many entries to a minimum. Human Drug Targets will prove invaluable to those drug discovery professionals, in both industry and academia, who need to make some sense of the bewildering array of online information sources on current and potential human drug targets. As well as creating order out of a complex target landscape, the book will act as an ideas generator for potentially novel targets that might form the basis of future discovery projects.
Download or read book New therapeutic targets for human placental angiogenesis diseases written by Carlos Alonso Escudero and published by Frontiers Media SA. This book was released on 2015-04-15 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: A large number of publications have described impaired angiogenesis and vasculogenesis present in the feto-placental circulation after pregnancy diseases such as pre-eclamptic pregnancies, gestational diabetes, and intrauterine growth restriction, among others. Results suggest impaired secretion and activity of pro-angiogenic factors such as vascular endothelial growth factor (VEGF), interleukin 8 (IL-8), adenosine and nitric oxide, associates with compromised secretion and activity of anti-angiogenic factors such as soluble receptor of VEGF (sFlt-1), thrombospondin 2, endostatin among others. More recent evidences include the participation of endothelial progenitor cells (EPC), which circulating number is reduced infeto-placental circulation in pregnancies such as pre-eclampsia. Despite this knowledge, therapies for placental angiogenesis recovery during pathological pregnancies are far to be tested. However, from the cardiovascular field, it has been described the administration of EPC, alone or used as gene-transfer therapy; or it has been described the potential role of statins (HMGCoA inhibitors), or angiotensin-converter enzyme (ACE) inhibitors for enhancing angiogenesis. Finally, feto-placental tissue is an exceptional source of progenitor and stem cells, which could be used for treated other human diseases such as stroke, myocardial infarction, hypertension, or even cancer. In this research topic, authors highlight physiopatological and clinical importance of the impaired placental angiogenesis, and suggest potential targets for developing innovative therapies.
Download or read book Deception in the Digital Age written by Cameron H. Malin and published by Elsevier. This book was released on 2017-06-30 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deception in the Digital Age: Exploiting and Defending Human Targets Through Computer-Mediated Communication guides readers through the fascinating history and principles of deception—and how these techniques and stratagems are now being effectively used by cyber attackers. Users will find an in-depth guide that provides valuable insights into the cognitive, sensory and narrative bases of misdirection, used to shape the targeted audience’s perceptions and beliefs. The text provides a detailed analysis of the psychological, sensory, sociological, and technical precepts that reveal predictors of attacks—and conversely postmortem insight about attackers—presenting a unique resource that empowers readers to observe, understand and protect against cyber deception tactics. Written by information security experts with real-world investigative experience, the text is the most instructional book available on the subject, providing practical guidance to readers with rich literature references, diagrams and examples that enhance the learning process. Deeply examines the psychology of deception through the lens of misdirection and other techniques used by master magicians Explores cognitive vulnerabilities that cyber attackers use to exploit human targets Dissects the underpinnings and elements of deception narratives Examines group dynamics and deception factors in cyber attacker underground markets Provides deep coverage on how cyber attackers leverage psychological influence techniques in the trajectory of deception strategies Explores the deception strategies used in today’s threat landscape—phishing, watering hole, scareware and ransomware attacks Gives unprecedented insight into deceptive Internet video communications Delves into the history and deception pathways of nation-state and cyber terrorism attackers Provides unique insight into honeypot technologies and strategies Explores the future of cyber deception
Download or read book The Human Target 2021 5 written by Tom King and published by DC Comics. This book was released on 2022-02-22 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: Christopher Chance, a.k.a. the Human Target, will be dead in a few days, but nothing will stop him from solving his own murder. His investigation into the JLI intensifies, and he sets his sights on the Martian Manhunter…but what piece does J’onn J’onzz add to the puzzle?
Download or read book Eco Targets Goal Functions and Orientors written by Felix Müller and published by Springer Science & Business Media. This book was released on 1998-04-08 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume comprises the proceedings of the International Workshop on Eco logical Goal Functions, held at the Schleswig-Holstein Cultural Center of Salzau, August 30 -September 4, 1996. The conference - first in a series - intended to be convened at Salzau at 1 -2 year intervals to address various aspects of theo retical and application-oriented ecology, was initiated, organized and carried out under the auspices of the Ecology Center of the Kiel University. It featured key note addresses, invited lectures, submitted papers, and posters. 32 contributions written by authors from eight countries, were selected to be presented in this book. From the very rich discussions of the workshop, some general characteristics emerged which might become important for a deeper understanding of the nature of evolving systems or, in other words, systems with a history, described by variables with a high degree of interdependence. These characteristics include the following: Speaking of 'goal functions' is a convenient 'fa~on de parler', since a logical analysis of the formal structure of teleological and causal explanations shows that both are analogous with regard to the inherent structural typology and the basic mode of explanation. Teleological interpretations introduce motives or objectives of actors into the set of 'antecedens' conditions relevant for system evolution, and are consequently a subset of causal interpretations.
Download or read book Soft Targets written by Deborah Landau and published by Copper Canyon Press. This book was released on 2019-06-18 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: Starred Review in Publishers Weekly: "Through the cadence of these poems, which sometimes resemble lullabies in their dreaminess and gorgeous lyricism, Landau captures the ways humans persist, despite our collective anxiety, in our longing for 'something tender, something that might bloom.'” Deborah Landau’s fourth book of poetry, Soft Targets, draws a bullseye on humanity’s vulnerable flesh and corrupted world. In this ambitious lyric sequence, the speaker’s fear of annihilation expands beyond the self to an imperiled planet on which all inhabitants are “soft targets.” Her melancholic examinations recall life’s uncanny ability to transform ordinary places—subways, cafes, street corners—into sites of intense significance that weigh heavily on the modern mind. “O you who want to slaughter us, we’ll be dead soon/enough what’s the rush,” Landau writes, contemplating a world beset by political tumult, random violence, terror attacks, and climate change. Still there are the ordinary and abundant pleasures of day-to-day living, though the tender exchanges of friendship and love play out against a backdrop of 21st century threats with historical echoes, as neo-Nazis marching in the United States recall her grandmother’s flight from Nazi Germany.
Download or read book Perfect Targets written by Rebekah Heinrichs and published by AAPC Publishing. This book was released on 2003 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: A 2002 study from Comprehensive Issues in Pediatric Nursing found that 94 percent of students with Asperger Syndrome face torment from their peers. Indeed, some of their behaviors and characteristics that others see as "different" make many of these children easy targets for frequent and severe bullying. This book takes a frank look at the different types of bullying and what adults must do to curb bullying, helping prevent the often lifelong effects of this behavior on its victims. Practical strategies and solutions at the school, class and individual level are presented.
Download or read book Therapeutic Targets written by Luis M. Botana and published by John Wiley & Sons. This book was released on 2012-04-20 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Latest Applications For Cellmechanism Research in Drug Discovery Designed to connect research on cell mechanisms with the drug discovery process, Therapeutic Targets: Modulation, Inhibition, and Activation introduces readers to a range of new concepts and novel approaches to drug screening and therapeutic drug targeting to help inform future avenues of drug research. Highly topical, this accessible edited volume features chapters contributed by respected experts from around the globe. The book helps postgraduate students and professional scientists working in academia and industry understand the molecular mechanisms of pharmacology, current pharmacological knowledge, and future perspectives in drug discovery, focusing on important biochemical protein targets and drug targeting strategies for specific diseases. Examining the pharmacology of therapeutically undefined targets and their potential applications, it includes chapters on traditional therapeutic targets, including enzymes (phosphodiesterases and proteases), ion channels, and G protein-coupled receptors, as well as more recently identified avenues of exploration, such as lipids, nuclear receptors, gene promoters, and more. Since different diseases require different targeting techniques, the book also includes dedicated chapters on strategies for investigating Alzheimer's, diabetes, pain, and inflammation treatments. Concluding with a cross-sectional look at new approaches in drug screening, Therapeutic Targets is an invaluable resource for understanding where the next generation of drugs are likely to emerge.
Download or read book Moving Targets written by Margaret Atwood and published by House of Anansi. This book was released on 2005 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most precious treasure of this collection is that it gives us the rich back-story and diverse range of influences on Margaret Atwood's work. From the aunts who encouraged her nascent writing career to the influence of George Orwell's Nineteen Eighty-Four on The Handmaid's Tale, we trace the movement of Atwood's fertile and curious mind in action over the years.Atwood's controversial political pieces, Napoleon's Two Biggest Mistakes and Letter to America -- both not-so-veiled warnings about the repercussions of the war in Iraq -- also appear, alongside pieces that exhibit her active concern for the environment, the North, and the future of the human race. Atwood also writes about her peers: John Updike, Marina Warner, Italo Calvino, Marian Engel, Toni Morrison, Angela Carter, Gabriel Garcia Marquez, Mordecai Richler, Elmore Leonard, and Ursula Le Guin.This is a landmark volume from a major writer whose worldwide readership is in the millions, and whose work has influenced and entertained generations. Moving Targets is the companion volume to Second Words.
Download or read book Targets of Hatred written by Eleanor J. Bader and published by St. Martin's Press. This book was released on 2015-02-10 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targets of Hatred charts the development of the anti-abortion movement in North America. Beginning in the years preceding the 1973 Roe vs. Wade decision that legalized abortion, the book examines the roles played by the Catholic Church, Fundamentalist Protestants, and Republican and Democratic parties, and assesses points of overlap and divergence. The voices of more than 190 providers in the United States and Canada--clinic owners, doctors, nurses, technicians, and their families--give readers an in-depth look at what it means to work in a field in which arson, bombings, harassment, and killing are routine. Filled with dramatic, eye-witness accounts of anti-abortion terrorism, the book demonstrates law enforcement's failure to stem the violence and is a call to arms for concerned individuals.
Download or read book Drugs from Nature Targets Assay Systems and Leads written by Madhathilkovilakathu Haridas and published by Springer Nature. This book was released on with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Improving and Accelerating Therapeutic Development for Nervous System Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 2014-02-06 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.
Download or read book Stalked the Human Target written by Rachel Cassidy and published by . This book was released on 2018-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stalked: The Human Target is a detailed account of the effects of stalking, which is experienced by a shockingly high proportion of the population. Celebrities like David Letterman and Madonna are the highest profile targets of stalkers, but ordinary people are also targeted, harassed and bullied. Rachel Cassidy, herself the target of a stalker, tells the stories of people who have been pursued by stalkers and the devastating effects that has had on their lives. Sometimes the stalker's behaviour becomes violent. Dancing with the Stars judge Mark Wilson had two dancing schools burned to the ground and his career destroyed. The man who stalked Jodie Foster attempted to assassinate President Reagan to gain her attention. Stalked is a perceptive analysis of stalking from the inside - told by the targets, the stalkers, and the experts who deal with the havoc wreaked by the people who harass or persecute others with unwanted and obsessive attention.
Download or read book Innocent Targets written by Michael Stephen Dorn and published by . This book was released on 2005 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Innocent Targets provides a balanced examination of rare but tragic events of school terrorism and what can be done about them. Co-authored by one of the few people in the United States who has actual experience working in a government school safety center as well as full time experience in a government antiterrorism unit, the book puts to rest the dangerous myths reported in the media which actually further the aims of terrorists.
