Download or read book Human Insulin by Tryptic Transpeptidations of Porcine Insulin and Biosynthetic Precursors written by Jan Markussen and published by Springer. This book was released on 1987 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Human Insulin by Tryptic Transpeptidations of Porcine Insulin and Biosynthetic Precursors written by J. Markusse and published by Springer. This book was released on 2014-09-12 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Human Insulin by triptic transpeptidations of porcine Insulin and biosynthetic precursors written by and published by . This book was released on 1987 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Highlights of Modern Biochemistry written by Arnošt Kotyk and published by VSP. This book was released on 1989-12 with total page 984 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 14th International Congress of Biochemistry was one of the most successful congresses ever held under the sponsorship of the International Union of Biochemistry. These Proceedings contain the papers from leading experts from all continents which were presented during the congress. The contributions in these volumes present the gigantic advances and new trends in all fields of biochemistry and give an idea of new developments in these fields.
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1060 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book Insulin written by Pedro Cuatrecasas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is fourteen years since insulin was last reviewed in The Handbook of Ex perimental Pharmacology, in volume 32. The present endeavor is more modest in scope. Volume 32 appeared in two separate parts, each having its own subeditors, and together the two parts covered nearly all areas of insulin pharmacology. Such comprehensiveness seemed impractical in a new volume. The amount of in formation related to insulin that is now available simply would not fit in a reasonable amount of space. Furthermore, for better or worse, scientists have be come so specialized that a volume providing such broad coverage seemed likely in its totality to be of interest or value to very few individuals. We therefore decided to limit the present volume to the following areas: insulin chemistry and structure, insulin biosynthesis and secretion, insulin receptor, and insulin action at the cellular level. We felt these areas formed a coherent unit. We also felt, perhaps as much because of our own interests and perspectives as any objective reality, that these were the areas in which recent progress has been most dramatic, and yet, paradoxically and tantalizingly, these were the areas in which most has yet to be learned. Even with this limited scope, there are some major gaps in coverage. Regrettably, two important areas, the beta cell ATP-sensitive potassium channel and the glucose transporter, were among these. Nevertheless, the authors who con tributed have done an excellent job, and we would like to thank them for their diligence.
Download or read book Galenics of Insulin written by Jens Brange and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Galenical pharmacy or galenics is the science dealing with the pro duction of drug substances from raw materials, the purity of such substances, their formulation into pharmaceutical preparations with the desired effects and safety in use, and the quality control, stability and storage of the preparations. The field has taken its name from the Greek physician Galen (131-201 A.D.), who had a profound influence on medicine for many centuries because he collected and systematized the medicinal knowledge of his time. The discovery of insulin is attributed to Banting and Best who, in 1921, prepared an extract of the pancreas of the fetal calf and showed that the extract was capable of reducing the blood sugar level of a diabetic dog. This outstanding discovery gave rise to the rapid develop ment of the manufacture of insulin of bovine and porcine origin. By 1925, two Danish manufacturers of insulin preparations were established; both have since been in the forefront ofthe development of insulin preparations, the latest achievement being the marketing of human insulin by Novo in 1982. The development of highly purified human insulin produced semisynthetically from porcine insulin or by DNA recombinant methods are significant contributions to safe and efficient insulin therapy. Insulin is a protein which is destroyed in the gastrointestinal tract.
Download or read book Enzyme Catalysis in Organic Synthesis 3 Volume Set written by Karlheinz Drauz and published by John Wiley & Sons. This book was released on 2012-03-26 with total page 2143 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive three-volume set is the standard reference in the field of organic synthesis, catalysis and biocatalysis. Edited by a highly experienced and highly knowledgeable team with a tremendous amount of experience in this field and its applications, this edition retains the successful concept of past editions, while the contents are very much focused on new developments in the field. All the techniques described are directly transferable from the lab to the industrial scale, making for a very application-oriented approach. A must for all chemists and biotechnologists.
Download or read book Protein Engineering by Semisynthesis written by Carmichael J.A. Wallace and published by CRC Press. This book was released on 1999-09-29 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: As genomics gives way to proteomics as the focus of scientific imagination in the biological sciences, more emphasis will be placed on the technology and interpretation of protein engineering experiments. Protein engineers will become increasingly sophisticated in the questions that they pose and demanding of the tools available to change protein structure. The optimal way to introduce non-coded amino acids for mechanistic studies, or site-specific reporter atoms for spectroscopic structural biology, is by protein semisynthesis. In Protein Engineering by Semisynthesis, the leading practitioners of the method cover their individual protein of expertise forming a comprehensive illustration of the various methods developed. By covering the most recent philosophical and methodological approaches and developments of semisynthesis and peptide synthesis to date, this book provides further understanding of the principles of protein structure-function relationships gained from semisynthetic analog in addition to providing a comprehensive and comprehensible laboratory guide. This book focuses on recent developments which synergistically combine chemical and molecular biological techniques that have made semisynthetic manipulations much easier to undertake. Features
Download or read book Peptide Therapeutics written by Ved Srivastava and published by Royal Society of Chemistry. This book was released on 2019-08-28 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptide therapy has become a key strategy in innovative drug development, however, one of the potential barriers for the development of novel peptide drugs in the clinic is their deficiencies in clearly defined chemistry, manufacturing and controls (CMC) strategy from clinical development to commercialization. CMC can often become a rate-limiting step due to lack of knowledge and lack of a formal policy or guidelines on CMC for peptide-based drugs. Regulators use a risk-based approach, reviewing applications on a case-by-case basis. Peptide Therapeutics: Strategy and Tactics for Chemistry, Manufacturing, and Controls covers efficient manufacturing of peptide drug substances, a review of the process for submitting applications to the regulatory authority for drug approval, a holistic approach for quality attributes and quality control from a regulatory perspective, emerging analytical tools for the characterisation of impurities, and the assessment of stability. This book is an essential reference work for students and researchers, in both academia and industry, with an interest in learning about CMC, and facilitating development and manufacture of peptide-based drugs.
Download or read book Amino Acids and Peptides written by J H Jones and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Download or read book Drug Biotechnology Regulation written by Y. Chiu and published by CRC Press. This book was released on 1991-01-07 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: An examination of the relation between biodrug development and governmental regulation, focusing on the present state of collective knowledge of biotechnological practitioners, including the identification of the scientific basis on regulatory requirements in the field, as well as ways in which the
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1988 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Peptides written by Norbert Sewald and published by John Wiley & Sons. This book was released on 2015-11-19 with total page 771 pages. Available in PDF, EPUB and Kindle. Book excerpt: Der "Sewald/Jakubke" ist und bleibt das einzige moderne, auf dem neuesten wissenschaftlichen Stand gehaltene fortgeschrittene Lehrbuch der Peptid-Biochemie! Auch für diese zweite, um ein Viertel erweitere Auflage haben die Autoren Hunderte von Publikationen gelesen und zu einem informativen und vollständigen Überblick über das Fachgebiet zusammengefasst. Nach einer Einführung in die Grundlagen der Peptidstruktur und -synthese werden die wichtigsten Familien biologisch aktiver Peptide systematisch abgehandelt. Mit interdisziplinärem Anspruch werden dann wichtige Anwendungen aus der Biotechnologie, Pharmazie und Biomedizin besprochen. Selbstverständlich werden auch Themen der Spitzenforschung berücksichtigt, zum Beispiel Pseudopeptide, Peptidmimetika und Aspekte der kombinatorischen Synthese. -- Neu in dieser Auflage sind Fragen und Übungsaufgaben, die das Nacharbeiten von Vorlesungen oder das Selbststudium erleichtern.
Download or read book Protein Design and the Development of New Therapeutics and Vaccines written by Jerry B. Hook and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on a symposium held November 1988, in King of Prussia, Penn. Among the topics: structural analysis of proteins, protein folding and stability, receptor design and regulation, guanine nucleotide binding protein family, modeling and structure prediction in macromolecules, protein engineering and
Download or read book Proteins Peptides and Amino Acids SourceBook written by John Stephen White and published by Springer Science & Business Media. This book was released on 2002-04-15 with total page 1071 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins, Pep tides and Amino Acids SourceBook is the second in a series of reference books conceived to cover the explosive growth in commercially available biological reagents. The success of our first reference work, Source Book of Enzymes published in 1997, encouraged us to continue this series. Choosing proteins, peptides, and amino acids as the subject matter for the second volume was simple, given their preeminence in regulating biochemical processes and their importance to modern molecular biology. The SourceBook series was inspired by our difficulty in locating a suitable replacement for a depleted reagent in the midst of an urgent research project. To our dismay, we found the reagent supplier out of business and the product line no longer available. Other reagent catalogs on our library bookshelf offered a narrow selection and incom plete functional information. We were ultimately able to locate a satisfactory alternative only by making countless inquiries and paging through innumerable product catalogs and technical data sheets. We needed-but could not find-a single resource that cataloged available compounds, organized them in a logical and accessible format, provided critical technical information to distinguish one from another, and told us where we could buy them.
Download or read book Enzymes in Food Processing written by Tilak Nagodawithana and published by Elsevier. This book was released on 2013-10-22 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past 35 years, the use of commercial enzymes has grown from an insignificant role in the food industry to an important aspect of food processing. This Third Edition of Enzymes in Food Processing explores recent and extensive changes in the use of enzymes as well as the discovery of new enzymes and their uses. Included in the book is a history of the role of enzymes in food processing, enzyme characterization, a discussion of different classes of enzymes including lipases and proteases, commercial enzyme production, and the processing of particular foods such as meat, vegetables, fruit, baked goods, milk products, and beer. Unlike earlier editions, it provides basic information on enzymes and their uses not adequately described in the current literature. Food technologists will find in this edition a description of the properties of those enzymes that are important in food processing, as well as a description of the properties of those enzymes that are important in food processing, as well as a description of the many applications of enzymes in the foods processing industry. The book is intended for food technologists, and will be of value to the microbiologist and enzyme chemist as well. This treatise provides a comprehensive treatment of enzymes used in food processing. - Covers genetic modification of enzymes in the food industry - Discuss enzyme function and dependence on environmental parameters - Explores practical applications of food enzymes in industry
