Download or read book Hormonal Contraception and Post menopausal Hormonal Therapy written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 1999 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evaluates evidence for an increased risk of cancer in women using combined oral contraceptives, progestogen-only hormonal contraceptives, post-menopausal estrogen therapy, and post-menopausal estrogen-progestogen therapy. Although the carcinogenicity of these preparations has been extensively investigated, the book stresses the many complex methodological issues that must be considered when interpreting findings and weighing results. Evidence of an association between use of these preparations and positive effects on health, including a reduced risk of some cancers, is also critically assessed. The first and most extensive monograph evaluates evidence of an association between the use of combined oral contraceptives and cancer at nine sites. Concerning breast cancer, the evaluation concludes that, even if the association is causal, the excess risk for breast cancer associated with patterns of use that are typical today is very small. Studies of predominantly high-dose preparations found an increased risk of hepatocellular carcinoma in the absence of hepatitis viruses. Citing these findings, the evaluation concludes that there is sufficient evidence in humans for the carcinogenicity of combined oral contraceptives. The evaluation also found sufficient evidence for the carcinogenicity of some, but not all, combined preparations in animals. Combined oral contraceptives were classified as carcinogenic to humans. The evaluation also cites conclusive evidence that these agents have a protective effect against cancers of the ovary and endometrium. Progestogen-only contraceptives are evaluated in the second monograph, which considers the association with cancer at six sites. The evaluation found no evidence of an increased risk for breast cancer. Although the evaluation found sufficient evidence in animals for the carcinogenicity of medroxyprogesterone acetate, evidence for the carcinogenicity of progestogen-only contraceptives in humans was judged inadequate. Progestogen-only contraceptives were classified as possibly carcinogenic to humans. The third monograph, on post-menopausal estrogen therapy, considers evidence of an association with cancer at eight sites. Findings from a large number of epidemiological studies indicate a small increase in the risk of breast cancer in women who have used these preparations for five years or more. Studies consistently show an association between use of post-menopausal estrogen therapy and an increased risk for endometrial cancer. Data on the association with other cancers were either inconclusive or suggested no effect on risk. The evaluation concludes that post-menopausal estrogen therapy is carcinogenic to humans. The final monograph evaluates the association between the use of post-menopausal estrogen-progestogen therapy and cancer at four sites. The evaluation of limited data on breast cancer found an increased relative risk observed with long-term use. Data were judged insufficient to assess the effects of past use and of different progestogen compounds, doses, and treatment schedules. For endometrial cancer, the evaluation found an increase in risk relative to non-users when the progestogen was added to the cycle for 10 days or fewer. Post-menopausal estrogen-progestogen therapy was classified as possibly carcinogenic to humans. Concerning post-menopausal therapy in general, the book notes that evidence of carcinogenic risks must be placed in perspective of potential benefits. The prevention of osteoporotic fractures is cited as the best-established benefit. Evidence also suggests that estrogen prevents heart disease and may prevent memory loss and dementia.

Download or read book Hormone Therapy written by Katherine Sherif and published by Springer Science & Business Media. This book was released on 2013-05-14 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormone Therapy: A Clinical Handbook provides a comprehensive overview on hormone replacement therapy, with a range of key features that differentiate it from other titles on the topic. This concise, handy title presents an interdisciplinary approach to the subject, acknowledging that sex hormones affect more than reproductive organs and hot flushes for a deeper understanding of how hormones function. The authors provide a breadth and depth of practical prescribing experience, including many helpful tables and algorithms as well as directions for prescribing hormone therapy in the most effective and safest ways possible. Targeted and easy to read, Hormone Therapy: A Clinical Handbook offers all clinicians the state-of-the-art information they need to prescribe hormone therapy and hormone replacement therapy.

Download or read book Hormonal Therapy for Male Sexual Dysfunction written by Mario Maggi and published by John Wiley & Sons. This book was released on 2011-11-17 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormonal therapy offers a potentially powerful approach to the treatment of sexual disorders in men. However the interplay of different hormones within different bodily systems is carefully balanced; judicious judgement is required in the therapeutic use of hormones to minimize unwelcome side effects. A better understanding of how hormones work will help the physician to better tailor therapies for improved sexual responses in men. Hormonal Therapy for Male Sexual Dysfunction will provide the rationale for hormonal therapy in male sexual disorders, explaining the language of sexual endocrinology and its application in clinical practice. The aim of this book is to provide a clinical 'in the office' or 'at the bedside' guide to effective patient care for sexual medicine physicians, urologists, gynecologists and other health-care providers in practice and in training. The tone will be practical, not academic. The working assumption is that readers want to know what (and what not) might or should be done, without over emphasis on the why. That said, it is important to review the crucial basic science necessary for effective diagnosis and management, and to provide reminders in the context of the practical chapters. It will not be heavily referenced, in line with a more practical approach. This allows for smoother reading (and also relieves the burden of comprehensive citing from authors). Key evidence (clinical trials, Cochrane or other meta analyses) should be summarized in 'Evidence at a Glance' boxes and key references such as reviews, major papers can be provided in the ‘selected bibliography’ at the end of each chapter. Practical guidance will be provided through: the use of algorithms and guidelines where they are appropriate 'Tips and Tricks' boxes – hints on improving outcomes perhaps via practical technique, patient questioning etc 'Caution' warning boxes – hints on avoiding problems, perhaps via contraindications 'Science Revisited' – quick reminder of the basic science principles necessary for understanding

Download or read book Menopause and Hormone Replacement written by Hilary O. D. Critchley and published by . This book was released on 2004 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Truth about Hormone Replacement Therapy written by Ellen Michaud and published by Prima Lifestyles. This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of both the potential hazards and benefits of hormone therapy after menopause.

Download or read book The Hormone Decision written by Tara Parker-Pope and published by Rodale. This book was released on 2007-01-09 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's the most pressing question on the minds of women at any stage of the menopausal transition: "Should I or shouldn't I take menopause hormones?" The answer is far from crystal clear. Hormone drugs are the most effective therapy for easing hot flashes and other common menopause symptoms. But their long-term effects have been the focus of intense scrutiny and debate. As the weekly consumer health columnist for The Wall Street Journal, Tara Parker-Pope has been an eyewitness to the growing controversy surrounding hormone therapy. Her understanding of menopause research, and her access to the experts behind it, has given her unique insight into the complex issues surrounding hormone use. In The Hormone Decision, Parker-Pope explores the scientific, political and social forces that have shaped current thinking on hormone therapy. And she takes you on a head to toe tour of how hormones affect every part of your body, including your brain, your breasts, your heart, your bones, your vagina, and even your skin. As you will discover, hormone therapy is not one-size-fits-all. It's as individual as your health status, family history and menopause experience. When you start hormone therapy and how long you use it are major factors in determining its health effects. While it may raise certain risks for some women, it actually may be protective for others. This is why you need an independent, objective resource like The Hormone Decision It provides the context for you to understand the research, ask intelligent questions, and ultimately choose whether or not hormone therapy is right for you.

Download or read book Growth Hormone Deficiency in Adults written by Jens O. L. Jørgensen and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been known for over 40 years that GH-deficient-children benefit from replacement with the hormone. But GH, essential for longitudinal growth, also plays a role after completion of final height. With the introduction of biosynthetic human GH 20 years ago, the use of GH was no longer restricted to severe growth retardation in hypopituitary children. This book will take the reader behind the myths of GH and into the real world of clinical endocrinology. The contributions stem from recognized clinicians and scientists who have been working in the field for decades. The contents encompass traditional end points of GH therapy such as body composition, bone biology and physical performance. Attention is also devoted to diagnostic aspects and side effects. Additional features range from clinical epidemiology to quality of life, and novel areas such as the impact of traumatic brain injury on pituitary function are also covered. The present volume of Frontiers of Hormone Research is essential reading for health care professionals interested in clinical endocrinology and GH.

Download or read book What You Must Know About Bioidentical Hormone Replacement Therapy written by Amy Lee Hawkins and published by Square One Publishers, Inc.. This book was released on 2013-02-12 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many women are confused about the treatments available for menopause. While they may be experiencing severe symptoms, the news about Hormone Replacement Therapy (HRT) use is not encouraging. HRT may increase the risk of heart attack, stroke, breast cancer, and blood clots in the lungs and legs. On the other hand, there is lesser known treatment-Bioidentical Hormone Replacement Therapy (BHRT)-that can help effectively diminish menopausal symptoms without the dangers of synthetic drugs. In her new book, Dr. Amy Lee Hawkins provides women with a complete guide to understanding and using BHRT to diminish or eliminate the symptoms of menopause. What You Must Know About Bioidentical Hormone Replacement Therapy is written in easy-to-understand language. It covers the basics of hormones, discusses the controversy surrounding hormone replacement, details hormone treatment principles, and provides a guide to maintaining a healthy weight and metabolism. Each discussion is supported by up-to-date scientific articles published in respected research journals and medical texts. In addition, the book's appendix includes numerous questionnaires that can help you understand your personal situation. If you are struggling with the symptoms of menopause, you want to choose the safest and most effective route to feeling better. What You Must Know About Bioidentical Hormone Replacement Therapy provides the information you need to make the best possible decisions about your health.

Download or read book International Differences in Mortality at Older Ages written by National Research Council and published by National Academies Press. This book was released on 2011-02-27 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1950 men and women in the United States had a combined life expectancy of 68.9 years, the 12th highest life expectancy at birth in the world. Today, life expectancy is up to 79.2 years, yet the country is now 28th on the list, behind the United Kingdom, Korea, Canada, and France, among others. The United States does have higher rates of infant mortality and violent deaths than in other developed countries, but these factors do not fully account for the country's relatively poor ranking in life expectancy. International Differences in Mortality at Older Ages: Dimensions and Sources examines patterns in international differences in life expectancy above age 50 and assesses the evidence and arguments that have been advanced to explain the poor position of the United States relative to other countries. The papers in this deeply researched volume identify gaps in measurement, data, theory, and research design and pinpoint areas for future high-priority research in this area. In addition to examining the differences in mortality around the world, the papers in International Differences in Mortality at Older Ages look at health factors and life-style choices commonly believed to contribute to the observed international differences in life expectancy. They also identify strategic opportunities for health-related interventions. This book offers a wide variety of disciplinary and scholarly perspectives to the study of mortality, and it offers in-depth analyses that can serve health professionals, policy makers, statisticians, and researchers.

Download or read book Hormones and Your Health written by Winnifred Cutler and published by Turner Publishing Company. This book was released on 2009-03-30 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many women are at a loss when it comes tocharting their best coursethrough menopause?butyou don't have to be Connecting recent scientific evidence among hormones, sexuality, bone and cardiovascular health, memory, surgery, and breast cancer, Dr. Cutler explains how valuable good HRT regimens are to your longevity and general health and how to improve your vitality with diet, exercise, and hormonal and alternative therapies that work. "Excellent job reviewing the many issues relating to perimenopause and menopause. . . . Your chapter on fibroids will be very valuable to consumers. The text is easy to follow, the illustrations are beautifully clear, and the references are excellent." ?John J. Sciarra, M.D., Ph.D., past president,International Federation of Gynecology and Obstetrics "What impressed me most were the passionate commitment to rigorously conducted research and the clarity with which the results were presented so any intelligent woman can understand them." ?Regula Burki, M.D., FACOG, gynecological surgeon and menopause specialist "Dr. Cutler dispassionately reviews and synthesizes the available literature to craft scientifically sound recommendations that can be used to optimize the quality of women's health." ?Elizabeth Genovese, M.D., FACOEM, FAADEP "A welcome reference for my patients and others interested in women's health. Readable, informative, and concise. Long overdue." ?Millicent Zacher, D.O., FACOG, Thomas Jefferson University

Download or read book The Menopause hormone therapy and women s health written by and published by DIANE Publishing. This book was released on with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book From Hormone Hell to Hormone Well written by Genie James and published by Simon and Schuster. This book was released on 2010-01-01 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: For much too long the traditional medical community has ignored, misdiagnosed, and mistreated millions of women suffering from symptoms of hormone imbalance. Now, a world-renowned expert explains a safer and more natural approach to treating hormone-related conditions like PMS, weight gain, mood swings, and hot flashes. The controversy continues to rage like hormones: The safety and efficacy of synthetic hormone replacement therapies (HRT) versus human-identical hormones. In this second edition of the widely successful guide From Hormone Hell to Hormone Well, world-renowned physician expert, C.W. Randolph, Jr., M.D., and Genie James team up to challenge the continual promotion by the pharmaceutical industry--and the physicians they have brainwashed--of dangerous synthetic hormones. In this hard-hitting book, Dr. Randolph and Ms. James expose the shocking truth that for decades, whenever most women have complained to their doctor about menopausal symptoms, the traditional approach treatment has put both their health and their lives at risk. As a board certified gynecologist who has treated women with hormone balances for over a decade, Dr. Randolph contends that there is--and has been--a safe and effective alternative to synthetic hormones: Bio-identical hormone replacement therapy (BHRT). Hormone Hell to Hormone Well shows readers how to: Eradicate a "one-size-fits-all" approach to HRT and empower women to discover and maintain her 'hormonal equilibrium' through her changing lifecycle Understand the new breakthroughs and discoveries in human-identical hormone therapy Naturally replace the hormones that have decreased with age--with the science that supports the health benefits of biidentical hormone therapy Enjoy vast improvements in mental and emotional health as well as resolving physical issues, including weight gain, depression, osteoporosis, hot flashes, low sex drive, and fatigue

Download or read book Modern Menopausal Hormone Treatment written by Hilde Löfqvist and published by Springer Nature. This book was released on 2022-02-10 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book is structured to give the reader a comprehensive view to understand the decline of hormones at midlife and the risks and benefits of evidence based hormonal treatments. The difference between bio-identical and synthetic hormones is shown. With this book the author intends to restore the trust of the mostly positive effects of hormone treatment during menopause. In this book effective hormone treatments that may be carried on for years are discussed. Those hormones may even prevent age related diseases (arthralgia, osteoporosis, cardiovascular diseases) if started at the right time frame directly after menopause, known as "window of opportunity". This book fills a gap for medical health providers and can be of benefit for all women searching evidence-based information and answers on hormone menopausal changes and treatments. The book provides the reader with case histories to show how different women are at the menopausal transition, and what the doctor has to consider in the choice of investigation and treatment.

Download or read book The Estrogen Elixir written by Elizabeth Siegel Watkins and published by JHU Press. This book was released on 2007-04-16 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the first complete history of hormone replacement therapy (HRT), Elizabeth Siegel Watkins illuminates the complex and changing relationship between the medical treatment of menopause and cultural conceptions of aging. Describing the development, spread, and shifting role of HRT in America from the early twentieth century to the present, Watkins explores how the interplay between science and society shaped the dissemination and reception of HRT and how the medicalization—and subsequent efforts toward the demedicalization—of menopause and aging affected the role of estrogen as a medical therapy. Telling the story from multiple perspectives—physicians, pharmaceutical manufacturers, government regulators, feminist health activists, and the media, as well as women as patients and consumers—she reveals the striking parallels between estrogen’s history as a medical therapy and broad shifts in the role of medicine in an aging society. Today, information about HRT is almost always accompanied by a laundry list of health risks. While physicians and pharmaceutical companies have striven to develop the safest possible treatment for the symptoms of menopause and aging, many specialists question whether HRT should be prescribed at all. Drawing from a wide range of scholarly research, archival records, and interviews, The Estrogen Elixir provides valuable historical context for one of the most pressing debates in contemporary medicine.

Download or read book Growth Hormone Therapy in Pediatrics written by Michael B. Ranke and published by Karger Medical and Scientific Publishers. This book was released on 2007-01-01 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: For 20 years, KIGS (Pfizer International Growth Database) has provided an outstanding tool for monitoring the use, efficacy and safety of growth hormone (GH) treatment in children with short stature of varying origin. This volume offers a comprehensive update of the continuing experiences in KIGS and is based on data from more than 50 countries and more than 60,000 patients. International experts analyse in detail the basic auxological characteristics of patients and their response to GH treatment for a broad spectrum of growth disorders. These include idiopathic GH deficiency, organic GH deficiency due to a variety of causes such as congenital malformations and syndromes, genetic disorders or treatment for leukaemia or central nervous system tumours and short stature in children born small for gestational age, specific syndromes and systemic disorders. Each growth disorder is also covered by a review of relevant published data by international experts. KIGS has also established itself as a primary source of information about adverse events during long-term GH treatment in children. The recent analysis of KIGS data has revealed no new adverse drug reactions since the 10-year follow-up. Therefore, treatment with GH seems a low-risk intervention in children and adolescents with various growth disorders. The process of developing disease-specific growth response prediction models has been ongoing in KIGS for many years. The available models are accurate, precise and have a relatively high degree of predictive power, although further predictors of the growth response remain to be identified. The KIGS prediction models can be applied prospectively to new patients, enabling their GH therapy to be better tailored and monitored to achieve optimal growth, safety and cost outcomes. The future of KIGS within the era of evidence-based medicine will continue to depend upon the quality of the data reported. Therefore, the commitment of participating physicians will continue to be a decisive element. The ongoing recognition of the importance of valid safety and efficacy information in the practice of paediatric endocrinology is exemplified by this valuable international collaboration of clinicians and the pharmaceutical community.

Download or read book Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research written by National Research Council and published by National Academies Press. This book was released on 2007-03-22 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is widely understood that stem cell treatments have the potential to revolutionize medicine. Because of this potential, in 2004 California voters approved Proposition 71 to set up a 10-year, $3 billion program to fund research on stem cells. Under the direction of the California Institute for Regenerative Medicine, this program will pay to build facilities for stem cell research and will fund doctors and scientists to carry out research with the ultimate goal of helping to develop therapies based on stem cells. For this research to move forward, however, will require a steady supply of stem cells, particularly human embryonic stem cells. Those stem cells are collected from developing human embryos created from eggs-or oocytes-harvested from the ovaries of female donors. Thus much of the promise of stem cells depends on women choosing to donate oocytes to the research effort. The oocyte donation process is not without risk, however. Donors are given doses of hormones to trigger the production of more eggs than would normally be produced, and this hormone treatment can have various side effects. Once the eggs have matured in the ovary, they must be retrieved via a surgical procedure that is typically performed under anesthesia, and both the surgery and the anesthesia carry their own risks. Furthermore, given the very personal nature of egg donation, the experience may carry psychological risks for some women as well. With this in mind, in 2006 the California Institute for Regenerative Medicine contracted with the National Academies to organize a workshop that would bring together experts from various areas to speak about the potential risks of oocyte donation and to summarize what is known and what needs to be known about this topic. The Committee on Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research was formed to plan the workshop, which was held in San Francisco on September 28, 2006. This report is a summary and synthesis of that workshop.

Download or read book Dr Susan Love s Menopause and Hormone Book written by Susan M. Love, MD and published by Harmony. This book was released on 2003-01-21 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the first edition of this important bestselling book, praised by Newsday as “the bible for a whole generation of menopausal women,” renowned physician and pioneering women’s health advocate Dr. Susan Love warned about the potential dangers of the long-term prescription of hormone replacement therapy. Her insightful words of caution have been backed up by the stunning results of the recent studies on hormone replacement. In this revised edition, Dr. Love offers a remarkably clear set of guidelines as to what the studies have shown about the risks regarding heart disease, breast cancer, stroke, and other conditions, and what effect hormone therapy has on osteoporosis. She offers definitive expert advice about whether or not to go on hormone replacement therapy and, if so, for how long, as well as how to taper off hormones; and she introduces the alternative methods for treating the symptoms of menopause. Dr. Love stresses that menopause is not a disease that needs to be cured—it is a natural life stage, and every woman ought to choose her own mix of options for coping with symptoms. A questionnaire about your own health history and life preferences helps you develop a program that will best fit your unique needs. With clarity and compassion, she walks you through every option for both the short and the long term, including: • lifestyle changes (diet, exercise, and stress management) • alternative therapies (including herbs and homeopathic remedies) • available medications other than hormones