Download or read book Hormonal Regulation of Estrogen and Progesterone Receptors in Mouse Mammary Glands in Vivo written by Yuqian Zhou and published by . This book was released on 1998 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Regulation and Function of Progesterone Receptor Isoforms A and B in the Normal Mouse Mammary Gland written by Mark Douglas Aupperlee and published by . This book was released on 2008 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Hormonal Regulation of Mammary Tumors Peptide and other hormones written by Benjamin S. Leung and published by . This book was released on 1982 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Hormonal Regulation of Mammary Tumors written by Benjamin S. Leung and published by Springer London. This book was released on 1982 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Control of the Mammary Cell Cycle Clock by Estrogen and Progesterone written by and published by . This book was released on 1999 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: Both the growth and the development of the mammary gland are controlled by the female hormones estrogen and progesterone, and by interactions between the epithelial and stromal compartments of the breast. Changes in the regulation of any of these processes may lead to breast cancer. Therefore, we need to understand in detail the mechanisms that control proliferation and development of the mammary gland. We have investigated the role of progesterone in the process of sidebranching and alveologenesis In the mammary gland using mice laclting the progesterone receptor which are defective in these processes. By reconstituting murine mammary glands in vivo, we have shown that the progesterone receptor is required only in epithelial cells for proper sidebranching to occur. Our studies suggest that progesterone acts in a paracrine manner and more recent data suggests that Wnt-4 is a possible mediator of this paracrine effect. In parallel studies, we have observed that breast cancer cells can dramatically downregulate the expression of hepatocyte growth factor in cocultured libroblasts. These results suggest an important role of paracrine interactions also in breast cancer development. In addition, we have characterized the role of the estrogen receptor in regulating the proliferation of breast cancer cells. We postulate that the ability of estrogen receptor to control cyclin Dl expression and proliferation of breast cancer cells may be acquired during breast cancer development. In conclusion, we have studied the role of female hormones and stroma-epithelial interactions in regulating mammary gland development and tumorigenesis.

Download or read book Hormonal Regulation of Lipid Synthesis by Mouse Mammary Gland in Vitro written by Joseph Alexander Cameron and published by . This book was released on 1973 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Regulation of the Progesterone Receptor in the Mouse Mammary Gland written by Emily Elizabeth Flynn and published by . This book was released on 2011 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Influence of Hormones on Fetal Mouse Mammary Glands in Vitro written by Brenda Pauline Alston and published by . This book was released on 1972 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Extracellular Matrix Regulation of Estrogen Receptors in Mouse Mammary Cells written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our previous results have shown that the basement membrane (BM) regulated the expression and function of estrogen receptor-alpha (ERa) in mouse mammary epithelial cells. New results shown here indicate that the presence of lactogenic hormones was required for the regulatory effect of BM on ERa levels. We present evidence that cell adhesion to the BM components collagen-IV, through alpha 2 and beta 1 integrin subunits and laminin-l, through alpha 2, alpha 6 and beta 1 subunits are the relevant interactions responsible for transducing the signal of the BM that increases ERa expression. On the other hand, BM- induced changes in cell proliferation and cell morphology were not involved. Thus, the changes observed in ER expression and estrogenic effect when mammary epithelial cells are removed from the gland and placed in culture could be due to the disruption of the tissue organization and, in particular, to the lack of cell-matrix interactions on tissue culture plastic. Our system model could be useful to better understand the mechanisms involved in the regulation of ER expression and function during mammary gland development and breast tumor progression.

Download or read book Hormonal Regulation of Mammary Tumor Virus Expression in Normal and Neoplastic Mouse Mammary Cells in Vitro written by Jason Yang and published by . This book was released on 1977 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Analysis of Progesterone Receptor Positive Cells in Relationship to Mammary Epithelial Cell Growth and Differentiation in Mouse Mammary Glands written by Sharianne G. Louie and published by . This book was released on 2000 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Mammary Gland written by Margaret C. Neville and published by Springer. This book was released on 1987-11-30 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Hormone dependent Differentiation of Rat Mammary Glands in Vitro written by William Grover Dilley and published by . This book was released on 1967 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Progestins and the Mammary Gland written by Orla M. Conneely and published by Springer Science & Business Media. This book was released on 2008-03-27 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progestins play a key role in reproductive endocrinology and as pharmaceutical drugs for contraception and in combined hormone therapy. To further our understanding of progestin action in the mammary gland, an international symposium, attended by leading researchers from academia and industry, was held in Berlin, 21–23 March 2007. Genetic mouse models helped to elucidate the role of progestins, both in normal breast development and in disease. Mechanistic molecular studies inspired the design of new progestins with improved tissue selectivity. In addition, the clinical impact of progesterone receptor agonists and antagonists for the prevention and treatment of breast cancer was discussed.

Download or read book Hormone Action written by Bert W. O'Malley and published by . This book was released on 1974 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormone assays; Hormone receptors; Evaluation of biological effects of hormones; Purification and synthesis of hormones.

Download or read book Protecting Infants through Human Milk written by Larry K. Pickering and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protecting Infants through Human Milk: Advancing the Scientific Evidence provides a forum in which basic scientists, clinicians, epidemiologists, and policy makers exchange the latest findings regarding the effects of human milk and breastfeeding on infant and maternal health, thereby fostering new and promising collaborations. This volume also integrates data from animal and in vitro laboratory studies with clinical and population studies to examine human milk production and composition, the mechanisms of infant protection and/or risk from human milk feeding, and proposed interventions related to infant feeding practices. Additionally, it stimulates critical evaluation of, and advances in, the scientific evidence base and research methods, and identifies the research priorities in various areas.

Download or read book Lactogenesis written by Monica Reynolds and published by University of Pennsylvania Press. This book was released on 2016-11-11 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a symposium, satellite to the 24th International Congress of Physiological Sciences, University of Pennsylvania.