Download or read book HIV AIDS Associated Viral Oncogenesis written by Craig Meyers and published by Springer. This book was released on 2018-12-06 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most important aspects of AIDS is the loss of protective immune function in the infected host which leads to increased prevalence of opportunistic infections and cancers. This book specifically addresses viral-induced human cancers associated with AIDS and observed in the AIDS population. It addresses the specific treatment required in this special population and the molecular biology of the causative viral agents.

Download or read book AIDS Associated Viral Oncogenesis written by Craig Meyers and published by Springer Science & Business Media. This book was released on 2007-05-04 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most important aspects of AIDS is the loss of protective immune function in the infected host which leads to increased prevalence of opportunistic infections and cancers. This book specifically addresses viral-induced human cancers associated with AIDS and observed in the AIDS population. It addresses the specific treatment required in this special population and the molecular biology of the causative viral agents.

Download or read book AIDS Associated Viral Oncogenesis written by Craig Meyers and published by Springer. This book was released on 2008-11-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most important aspects of AIDS is the loss of protective immune function in the infected host which leads to increased prevalence of opportunistic infections and cancers. This book specifically addresses viral-induced human cancers associated with AIDS and observed in the AIDS population. It addresses the specific treatment required in this special population and the molecular biology of the causative viral agents.

Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Download or read book Cancers in People with HIV and AIDS written by Robert Yarchoan and published by Springer. This book was released on 2014-07-10 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The association between AIDS and cancer was recognized from the beginning of the AIDS epidemic, when the appearance of Kaposi sarcoma in a cluster of young men was one of the first signs of this new disease. It was soon recognized that AIDS was caused by infection with a novel virus (HIV) and that AIDS patients are prone to develop a number of “AIDS-defining” cancers: Kaposi sarcoma, lymphoma, and cervical cancer. The development of effective combination anti-HIV therapy starting around 1996 converted AIDS from a death sentence to a manageable disease and led to dramatic shifts in the epidemic. As this therapy was able to improve immune function in patients, the incidence of most “AIDS-defining” cancers decreased. There is a misconception, however, that AIDS has gone away. In fact, as AIDS patients are living longer, the number of AIDS patients has more than doubled in the United States since 1996, and the AIDS population overall has increased in age. Also, as AIDS patients are less likely to die of other complications, cancer is coming to the forefront as one of the most common causes of death in regions where AIDS drugs are widely available. Moreover, the three “AIDS-defining” cancers are now taking a back seat to a number of other HIV-associated cancers, such as Hodgkin lymphoma, lung cancer, and anal cancer. In the developing world, AIDS-associated cancers are a major public health problem, and in some regions of sub-Saharan Africa, Kaposi sarcoma is the most common tumor in men. In recent years, there has been a vast increase in our understanding of HIV-associated cancers. We now know, for example, that most are caused by other viruses and that the main role of HIV and immunodeficiency is to provide a supportive environment for the viruses to multiply and for the cancers to develop. But there remain a number of unanswered questions and a need for improved prevention and therapy. In the 28 chapters of this book, written by some of the most renowned experts in this field, we present up-to-date information on the cancers associated with HIV infection. The chapters cover the epidemiology of these cancers, their pathogenesis, their clinical presentation, and their treatment. The book will be of value to physicians, other medical professionals, students, and researchers with an interest in AIDS, viral-associated cancers, or HIV-associated malignancies. TABLE OF CONTENTS 1. HIV-associated Cancers: Overview Robert Yarchoan, Thomas Uldrick, Mark Polizotto 2. Epidemiology of AIDS-defining Malignancies William A. Blattner and Rebecca G. Nowak 3. Epidemiology of non-AIDS Defining Malignancies Andrew E. Grulich 4. HIV Cancers in Resource-Limited Regions Sam M. Mbulaiteye 5. Kaposi's Sarcoma-associated Herpesvirus (KSHV) Blossom Damania and Dirk P. Dittmer 6. Epstein Barr Virus (EBV) Lindsey Hutt-Fletcher 7. Human Papillomavirus (HPV) Zhi-Ming Zheng 8. Merkel Cell Polymavirus (MCV) Nicole Fischer and Adam Grundhoff 9. Presentation and Pathogenesis of Kaposi's Sarcoma Corey Casper 10. Management of Kaposi's Sarcoma Susan E. Krown 11. Presentation and Pathogenesis of HIV Lymphomas Richard F. Little, Stefania Pittaluga, Kieron Dunleavy 12. Diffuse Large B-Cell Lymphoma Neel K. Gupta and Lawrence D. Kaplan 13. Burkitt and Burkitt-Like Lymphoma Kishor Bhatia and Sam M. Mbulaiteye 14. Primary Effusion Lymphoma Giovanna Tosato 15. AIDS-related Central Nervous System Lymphoma Jan Davidson-Moncada and Thomas Uldrick 16. Plasmablastic and Other Lymphomas Huan-You Wang, Ida Wong-Sefidan, Erin Reid 17. Hodkin Lymphoma Michele Spina, Rosanna Ciancia, Accursio Augello 18. Multicentric Castelman Disease Mark N. Polizzotto, Thomas S. Uldrick, Robert Yarchoan 19. Cervical Cancer Elizabeth A. Stier 20. Anal Cancer Joel Palefsky 21. Other HPV-Associated Cancers Kristina R. Dahlstrom and Erich M. Sturgis 22. Lung Cancer in HIV Infection Deepthi Mani and David M. Aboulafia 23. Hepattocellular Carcinoma in HIV-positive Patients Massimiliano Berretta, Paolo De Paoli, Umberto Tirelli, Bruno Cacopardo 24. Merkel Cell Carcinoma and Other HIV-associated Skin Cancers Nathalie C. Zeitouni adn Bethany Lema 25. Conjuctival Carcinoma Kenneth O. Simbiri and Erle S. Robertson 26. Malignancies in Children with HIV Infection D. Cristina Stefan 27. cART and Supportive Care Ronald T. Mitsuyasu 28. Stem Cell Transplantation Christine Durand and Richard Ambinder

Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Download or read book Molecular Basis for Therapy of AIDS Defining Cancers written by Dirk P. Dittmer and published by Springer Science & Business Media. This book was released on 2010-06-14 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer incidences increase in people living with HIV/AIDS. Over 2 million people currently live with HIV/AIDS in the US. This number will increase as HAART prolongs the average lifespan and as (at least in some states) the number of new HIV infections increase again. As this population ages their incidence rates for cancer will increase, as well. Recently, new rational targets for cancer therapy have emerged. But their application to the care of HIV+ patients is slow, because of concerns about the weakened immune status of the patients, because of possible drug interactions with HAART and because some of the AIDS defining cancer are rare.

Download or read book Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Download or read book Human Oncogenic Viruses written by Jing-hsiung James Ou and published by World Scientific. This book was released on 2010 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viruses are the causes of approximately 25% of human cancers. Due to their importance in carcinogenesis, there is a desperate need for a book that discusses these viruses. This book is therefore timely, providing a comprehensive review of the molecular biology of oncogenic viruses and the cancers they cause. Viruses that are discussed in the individual chapters include hepatitis B virus, hepatitis C virus, human papilloma viruses, EpsteinOCoBarr virus, Kaposi's sarcoma virus and human T-cell leukemia virus type 1. This book provides up-to-date information for graduate students, postdoctoral fellows, medical students, physicians and non-experts who are interested in learning more about the oncogenic viruses and how they cause human cancers. Sample Chapter(s). Foreword (38 KB). Chapter 1: Oncogenic Viruses, Cellular Transformation and Human Cancers (211 KB). Contents: Oncogenic Viruses, Cellular Transformation and Human Cancers (Y-Y Zheng & J-H J Ou); Hepatitis B Virus and Hepatocellular Carcinogenesis (T S B Yen); Molecular Mechanism of Hepatitis C Virus Carcinogenesis (K Machida et al.); Human Papillomaviruses and Associated Malignancies (C L Nguyen et al.); Epstein-Barr Virus and Its Oncogenesis (H-P Li et al.); Human Kaposi's Sarcoma-associated Herpesvirus: Molecular Biology and Oncogenesis (P J Dillon & B Damania); Human T-Cell Leukemia Virus 1 and Cellular Transformation (Y-H Chi & K-T Jeang). Readership: Graduate students and postdoctoral fellows in infectious diseases, microbiology/virology, oncology/cancer research, and cell/molecular/structural biology; medical students, physicians and non-experts who are interested in understanding the relationship between oncogenic viruses and the cancers they cause

Download or read book Viral Oncology written by Kamel Khalili and published by John Wiley & Sons. This book was released on 2010-08-03 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical oncologists and researchers now have a comprehensive single source of current information on cancer viruses obtained from bench and bedside. This important refernce allows further development of translational approaches for the effective treatment of patients with virus-associated malignancies. The book contains 25 chapters covering basic and clinical aspects of viruses, including HPV, HBV, HCV, polyomaviruses, Kaposi’s associated viruses, retroviruses (including HIV-1 associated malignancies), and EBV. Several chapters are devoted to basic science of oncogenic viruses for the study of their pathogenesis, drug development, and employment of viral vectors for vaccine and gene therapy. Clinical materials are embedded within chapters, and there are also complementary, clinically based chapters describing natural courses and treatments.

Download or read book Viruses and Human Cancer written by Mei Hwei Chang and published by Springer Science & Business Media. This book was released on 2013-09-06 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on oncogenic viruses and related human cancers has advanced rapidly in the past decade. Most articles, however, focus on a specific oncogenic virus and cancer. There is consequently a need for a comprehensive, up-to-date monograph that offers broad and integrated knowledge. Viruses and Human Cancer – From Basic Science to Clinical Prevention is designed to meet this need by providing an advanced overview on the basic and clinical aspects of oncogenic viruses and the human cancers that they cause. Virology, virus-induced inflammation and tissue injuries, oncogenic mechanisms, epidemiology, and current and emerging preventive and therapeutic strategies are all discussed in detail. In addition, the book covers the individual aspects of seven oncogenic viruses, i.e., hepatitis B virus, hepatitis C virus, human papilloma virus, Epstein-Barr virus, human T-cell lymphotropic virus, Kaposi sarcoma-associated herpes virus, and Merkel cell polyomavirus, and the related human cancers.

Download or read book Human Oncogenic Viruses written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book HIV AIDS written by Nancy Dumais and published by BoD – Books on Demand. This book was released on 2017-02-22 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: With increasing efficacy of antiretroviral therapy, HIV/AIDS has shifted from a disease with high mortality to a chronic illness with substantial longevity. However, researchers, physicians and social workers still face many challenges, and it is important to raise awareness on several aspects that people living with HIV/AIDS have to deal in their daily lives. This book has assembled an array of chapters on the medical, social and economic aspects of HIV/AIDS. The chapters were written by experts from around the globe reflecting the importance of the topic. This book will be of great interest not only to graduate students but also to active academics and practitioners.

Download or read book The Epstein Barr Virus written by M. A. Epstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Epstein-Barr virus was discovered 15 years ago. Since that time an immense body of information has been accumu lated on this agent which has come to assume great signifi cance in many different fields of biological science. Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole cular virology, since it is the cause of infectious mononu cleosis and also the first human cancer virus, etiologically related to endemic Burkitt's lymphoma and probably to nasopharyngeal carcinoma. In addition, continuous human lymphoid cell lines initiated and maintained by the transform ing function of the virus genome provide a laboratory tool with wide and ever-growing applications. Innumerable papers on the Epstein-Barr virus have ap peared over recent years and reports of work with this agent now constitute a veritable flood. The present book provides the first and only comprehensive, authoritative over-view of all aspects of the virus by authors who have been the original and major contributors in their particular disciplines. A complete and up-to-date survey of this unique and important agent is thus provided which should be of great interest to experts, teachers, and students engaged in cancer research, virology, immunology, molecular biology, epide miology, and cell culture. Where topics have been dealt with from more than one of these viewpoints, some inevitable overlap and duplication has resulted; although this has been kept to a minimum, it has been retained in some places because of positive usefulness.

Download or read book Viral and Immunological Malignancies written by Paul Volberding and published by PMPH-USA. This book was released on 2006 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: The precise relationship between viral infection and malignancy remains an epidemiologic association and the subject of active investigation. Nonmalignant hematologic disorders have a similarly complex relationship with cancer-associated viruses and may offer insight into the pathogenesis of oncogenesis. This book explores the relationships between viral infections, immune impairments and the hematologic and malignant diseases, particularly against the backdrop of the HIV epidemic. By extending the scope to all of viral oncology the editors provide an invaluable resource on tumors related to other viruses other than HIV, particularly carcinomas of the cervix and anus with HPV and tumors of the liver with the various hepatitis viruses.

Download or read book HIV HTLV I Associated Malignancies written by Joseph A. Sparano and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infection with the human immunodeficiency virus (HIV) and human T-cell lymphotropic virus type I (HTLV-I) is known to be associated with an increased risk of neoplastic disorders, especially Kaposi's sarcoma and aggressive B-cell lymphoma for the former, and T-cell lymphoma for the latter. The information obtained from the study of these infections has led to remarkable advances in our understanding of the immune system, as well as the biology of human neoplasms. The management of malignant diseases in such patients also poses substantial challenges to clinicians. This book provides an overview of the epidemiology, biology, clinical features, and clinical management of neoplasms occurring in such individuals. It is an important resource for clinicians treating these diseases, and for basic scientists who have an interest in this field.

Download or read book Cancer and AIDS written by Christopher Kwesi O. Williams and published by Springer. This book was released on 2018-10-30 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt: The lifestyles and socio-economic status that are prevalent in regions of the world with limited resources form the background for the unique features of neoplastic diseases in these areas, where the majority of the world population lives. The predominance of the world’s retroviral burden of in these areas further compounds the nature and challenges of the cancer there. Much of the international cancer literature covers the nature and challenges of the disease as seen in high-income regions of the world, thereby giving a skewed view of the global cancer challenges. As the low- and middle-income regions of the world transition from communicable to non communicable disease patterns, there is a need for a corresponding paradigm shift, with increased emphasis on what the world needs to know about non communicable diseases, including cancer, where the disease is hitherto poorly documented. The main goal of the proposed book is to contribute to this outcomes.