Download or read book Chronic Liver Failure written by Pere Ginès and published by Springer Science & Business Media. This book was released on 2010-11-03 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.
Download or read book Hepatic Encephalopathy in Chronic Liver Failure written by Livio Capocaccia and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: The meeting which took place in Rome on November 19th and 20th of 1982 is easily the best meeting on hepatic coma that I have ever attended, and I have attended many. It was an exceedingly we- planned meeting with prolonged opportunity for discussion, and there was genuine interplay and exchange of ideas (not the usual picture of a rushed meeting with investigators presenting their own point of view and talking past each other without a meaningful ex change) which took place in Rome. My co-editors and I hope that the published transcript, which of course can only reflect what transpired in Rome on those two days, does justice to a very intellectually exciting and gratifying ex change of ideas. L. Capocaccia, J. E. Fischer and F. Rossi-Fanelli v CONTENTS Introduction 1 SECTION 1: PATHOGENETIC PROBLEMS IN HEPATIC ENCEPHALOPATHY Ammonia: The old and the new • • . • • • . • . • • • . • . • 5 L. Zieve Role of synergism in the pathogenesis of hepatic encephalopathy • • • • . • • . . . . • 15 L. Zieve y-Aminobutyric acid receptors in experimental hepatic encephalopathy •. •. • • 25 M. L. Zeneroli, ~. Baraldi,and E. Ventura A possible role for excitatory neurotoxic amino acids in the pathogenesis of hepatic en 41 cephalopathy • • • • • • • • • • • • • • • F. Moroni, G. Lombardi, G. Moneti, D. Pellegrini and C.
Download or read book Drug Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
Download or read book Encephalopathy and Nitrogen Metabolism in Liver Failure written by E. Anthony Jones and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encephalopathy and Nitrogen Metabolism in Liver Failure contains research reports and state-of-the-art reviews that were presented at the 11th International Symposium on Hepatic Encephalopathy and Nitrogen Metabolism in relation to liver disease, that was held in Amsterdam, The Netherlands from 30 May to 1 June, 2002. Themes covered include the metabolism of ammonia and amino acids in relation to liver disease, the assessment of hepatic encephalopathy (HE), minimal HE, animal models of HE, neuropsychiatric dysfunction in patients with chronic liver disease, the pathogenesis of HE, the astrocyte in liver disease, acute liver failure and cerebral edema, treatment of HE and artificial liver support systems. This volume provides an indispensable source of important new research findings and ideas for clinicians and biomedical scientists working in the field of HE and nitrogen metabolism in relation to liver disease.
Download or read book Hepatic Encephalopathy written by Kevin D. Mullen and published by Springer Science & Business Media. This book was released on 2012-05-30 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of the increasing burden of hepatitis C and fatty liver disease, there is an explosion in the prevalence of chronic liver failure and hence its complications. The onset of Hepatic Encephalopathy (HE) in these patients has a significant impact on the quality of life, morbidity and mortality. Unfortunately, the approach observed by most clinicians to this complex disorder is minimalistic. This book provides a comprehensive review on pathophysiology and clinically important aspects in HE. Topics in basic physiology, nitrogen metabolism, new insights into pathogenesis and brain edema are covered in great detail. The authors have made a special effort by simplifying the complex aspects of pathogenesis and diagnosis so that it can be easily understood and applied clinically. This volume also focuses on recent developments regarding diagnoses of subtle forms of HE, also known as minimal or covert HE as well as on new treatments. Hepatic Encephalopathy will be of great value to gastroenterologists, hepatologists, pathologists, medical residents, fellows, internists and general practitioners who treat patients with hepatic encephalopathy.
Download or read book Brain Disorders in Critical Illness written by Robert D. Stevens and published by Cambridge University Press. This book was released on 2013-09-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.
Download or read book Handbook of Liver Disease written by Lawrence Samuel Friedman and published by . This book was released on 2004 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here's instant access to the symptoms, signs, differential diagnosis, and treatment for the full range of liver disorders. Written by an international 'who's who' of hepatology-and now in full color-this new 2nd Edition provides readers with top-notch, authoritative guidance they can count on! Discusses the hottest topics in the field, such as non-alcoholic steatohepatitis (NASH) and the latest information on liver transplantation. Includes expanded coverage of chronic hepatitis C, most notably the use of combination therapy with peginterferon and ribavirin and improvements in the management of the side effects of antiviral therapy. Offers the most recent therapeutic options for the management of chronic hepatitis B and advances in the understanding of the molecular biology of this virus. Updates the approach to the diagnosis of many liver diseases due to newer tests based on molecular techniques and advances in imaging. Features over 340 full-color illustrations. Uses a redesigned templated, outline format that makes reference a snap. Presents a concise, in-depth clinical summary-in an outline format-of the current practice of hepatology for each major disease entity. Provides a liberal use of tables, algorithms, and figures, rendering complex concepts understandable. Includes key point boxes at the beginning of each chapter, providing at-a-glance access to vital information. Includes alert symbols that highlight information that's critical to patient safety.
Download or read book Hepatocyte Transplantation written by S. Gupta and published by Springer Science & Business Media. This book was released on 2002-09-30 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years there has been an increasing need for transplantation, but the number of donor livers available has increased only slightly, despite intensive public relations activities. New concepts in the field of transplantation, for instance the transplantation of living donor organs or the splitting of organs, are urgently required, to safeguard the treatment of patients with severe liver disease. The development and clinical application of cell therapy for patients with liver disease could soon present a significant enhancement of the therapeutic options. The aim of such cell therapy is to repair or improve the biological function of the chronically and acutely damaged liver. Even though systematic trials are not available, individual case reports and small series already show promising clinical results. Present concepts of cell therapy for liver diseases based on the use of primary hepatocytes have recently been considerably extended through new data on the biology of stem cells. The adult haematopoetic stem cell as a pool for hepatocyte grafts - what would be the perspectives for the clinical application? This book is the proceedings of the Falk Symposium No. 126 on `Hepatocyte Transplantation' (Progress in Gastroenterology and Hepatology Part III) held in Hannover, Germany, October 2-3, 2001, and is a forum for basic research, but also for questions concerning clinical applications in the field of hepatocyte transplantation.
Download or read book Liver Disease in Children written by Frederick J. Suchy and published by Cambridge University Press. This book was released on 2021-03-18 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver disease in children is increasing in prevalence, placing a huge burden on healthcare systems and often requiring long-term management. Offering an integrative approach to the science and clinical practice of pediatric hepatology, this is the definitive reference text for improved diagnosis and treatment strategies. In the new edition of this authoritative text, chapters have been thoroughly revised in line with major advances in the field, such as recognizing the increased frequency of fatty liver disease, and how genetic testing has the potential to establish earlier diagnoses for a variety of diseases. Disorders covered include cholestasis, metabolic disorders and hepatitis, with their presentation across the spectrum of infancy, childhood and adolescence discussed. The indications and surgical aspects of liver transplant are explained and post-transplant care is described in detail. This is a valuable resource for pediatricians, hepatologists, gastroenterologists and all clinicians involved in the care of children with liver diseases.
Download or read book Hepatic Encephalopathy written by Roger F. Butterworth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Advances in Hepatic Encephalopathy An Issue of Clinics in Liver Disease written by Robert S. Brown Jr and published by Elsevier Health Sciences. This book was released on 2015-10-19 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Brown provides a timely upate on the clinical diagnosis and management of Hepatic Encephalopathy. His issue addresses current hot topics including Role of NH4 in Pathogenesis of Hepatic Encephalopathy; How to diagnose and manage HE in fulminant hepatic failure; New methods of Brain Imaging and testing (eg PET) and Hepatic Encephalopathy; Management New agents for HE (focus on NH4 lowering drugs used in UCD); Legal responsibility of MD when he diagnoses HE; Diets in Encephalopathy; and Neurological manifestations of HE.
Download or read book The Complex Interplay Between Gut Brain Gut Liver and Liver Brain Axes written by Cristina Stasi and published by Academic Press. This book was released on 2021-04-06 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Complex Interplay Between Gut–Brain, Gut–Liver, and Liver–Brain Axes provides current and wide-ranging information in the field of gastrointestinal, liver, and brain interactions that can be used in resolving important clinical issues. This book is systematically split into three distinct sections. The first section introduces the pathophysiology of the gut–brain connection, including the causative effect of the interactions between the gut and brain in gastrointestinal and psychiatric/neurological disorders, and the role of serotonin and its pathways in gastrointestinal disorders. The second section examines the pathophysiology of the gut–liver connection along with the interactions between gut microbiota and liver in chronic liver diseases, with special focus on the role of serotonin and its pathways in hepatic fibrogenesis. Finally, the third section describes the pathophysiology of the liver–brain connection, including the role of gut microbiota in hepatic encephalopathy, as well as dietary and therapeutic interventions that target the gut microbiome. Provides current and wide-ranging knowledge in the field of gastrointestinal, liver, and brain interactions Resolves important clinical issues concerning gut, liver, and brain interactions Demonstrates advances in the understanding of the pathophysiology of gastrointestinal and liver diseases
Download or read book Diagnosis and Management of Hepatic Encephalopathy written by Jasmohan S. Bajaj and published by Springer. This book was released on 2018-05-23 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive, state-of-the-art overview of hepatic encephalopathy. Through a case-based approach, the text reviews new data and studies about the role of microbiota in liver disease and hepatic encephalopathy, explores the burden of hepatic encephalopathy on readmissions, costs, and patient care, and highlights management strategies for patients in differing stages of hepatic encephalopathy. Exploratory new therapies and treatment targets are also discussed in the guide. Written by experts in the field, Diagnosis and Management of Hepatic Encephalopathy: A Case-based Guide is a valuable resource for physicians and researchers who deal with this challenging complication of cirrhosis.
Download or read book Liver Disease and Surgery written by Georgios Tsoulfas and published by BoD – Books on Demand. This book was released on 2019-11-27 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this book is to present a review of the different categories of liver disease, as well as address the role of surgery in managing these complex diseases. The book includes chapters written by international experts on the most current indications and guidelines regarding the diagnoses and management of liver diseases, as well as a variety of technical elements involved with the surgical procedures. Different surgical techniques involved in performing a hepatectomy will be discussed, including various instruments used, as well as the effect of modern technology as evidenced by novel procedures. An important focus of the book has been identifying the proper place of all these hepatectomy methods in the armamentarium of the experienced hepatobiliary surgeon, including the role of locoregional treatments such as ablation and embolization as adjuncts. Finally, the role of hepatectomy compared to orthotopic liver transplantation is discussed, so that the reader can have a well-rounded picture of the challenges and opportunities involved. Overall, this book has the potential to serve as an invaluable "tool" for both the hepatologist and the internist, as well as for the hepatic surgeon
Download or read book Variceal Bleeding written by David Westaby and published by . This book was released on 1982 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book ICU Protocols written by Rajesh Chawla and published by Springer Nature. This book was released on 2019-12-31 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this highly successful book includes up-to-date notes on the step-wise management of clinical emergencies encountered in everyday intensive care units (ICU). Each thoroughly revised chapter provides concise information for point-of-care treatment, making it a practical guide clinicians can refer to on a daily basis at work or while traveling, or just to expand their knowledge. Volume 1 of ICU Protocols covers topics in pulmonology, cardiology, neurology, gastroenterology, nephrology and infectious diseases. The endocrine and metobolic systems, oncology, trauma, toxicology, envenomation and thermodysregulation, obstetrics, and perioperative care are covered in the second volume of ICU Protocols. This two-volume book is a must-read for intensivists, critical care specialists, junior trainees and residents working in ICUs. It is also relevant as course material for workshops on critical care, and essential for all hospital-based libraries. “This book provides junior trainees with an introduction to the management of problems common to the critical care unit.” David J Dries, Doody’s Book Reviews, March, 2013, for the first edition of ICU Protocols.
Download or read book Pediatric Liver Intensive Care written by Naresh Shanmugam and published by Springer. This book was released on 2018-09-28 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute management of children with liver disease and liver transplantation has rapidly evolved over the last two decades due to worldwide availability of complex liver surgery and liver transplantation. This book edited by Prof Dhawan and Dr Shanmugam, who have hands on experience in managing children with complex liver disease, its complications and liver transplant recepients, provides to a very practical approach to all the team members involved in paediatric transplantation like ; Hepatologists, anaesthetists, surgeons, intensivists, transplant coordinators, nurses and trainees at all levels and specialities. Topics covered include management of common liver problems, liver based metabolic disorders and peri-operative care protocols in paediatric liver transplantation. It also provides up to date information on drug dosage and infusion calculations for common drugs used in liver disease.