Download or read book Hemoglobin and Red Cell Structure and Function written by George Brewer and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemoglobin and the red cell have continued to set a dizzying pace as the objects of research in the two and one-half year interval since the First International Conference on Red Cell Metabolism and Function. Most exciting perhaps, is a beginning molecular attack on sickle cell disease. The story of the inter action of red cell metabolism and oxygen transport has continued to unfold, and we can now infer that patients with hypoxia usually utilize red cell metabolic adjustments to improve oxygenation. This puts the red cell squarely in the center of medical practice, since much of medicine-heart, pulmonary, and blood disease- deals with inadequate oxygenation. On April 27th through the 29th, 1972, crystallographers, chemists, biochemists, physiologists, geneticists, and physi cians from many medical disciplines met in the Towsley Center for Continuing Medical Education at the University of Michigan, Ann Arbor to present new data, to review recent developments, and to try to piece together additional features of the red cell puzzle. The meeting was dedicated to Dr. Francis John Worsley Roughton, Professor Emeritus of Colloid Science, University of Cambridge, England, in recognition of his numerous excellent contributions to the understanding of hemoglobin and red cell function. The program got off to a good start with a paper from M. F. Perutz, Nobel Laureate, on the structure of hemoglobin. Dr.
Download or read book Hemoglobin and Red Cell Structure and Function written by George J. Brewer and published by . This book was released on 1972 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Red Blood Cell written by Douglas Surgenor and published by Elsevier. This book was released on 2012-12-02 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Red Blood Cell, Second Edition, Volume I provides information pertinent to red blood cells, which is the most intensely studied human tissue. This book reviews the basic biomedical knowledge about the circulating, red blood cells. Organized into 13 chapters, this edition starts with an overview of the discovery of red blood cells, which results in the growth of knowledge in the areas of clinical disease and therapeutic efforts. This book then discusses the significant functions of the red blood cells, which exists basically to transport the respiratory gases. Other chapters examine the red blood cell’s capacity for protein synthesis and its ability to diversify its function. This book discusses as well the progress in the structural analysis of lipids. The final chapter deals with the capacity to store red blood cells frozen for long periods with high yield of viable physiological functional cells after post-thaw processing. Scientists, physicians, teachers, researchers, and students will find this book extremely useful.
Download or read book Red Blood Cell Membranes written by Peter Agre and published by CRC Press. This book was released on 2020-08-11 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to the red blood cell membrane, its structure and function, and abnormalities in disease states. It presents a well-documented and well-illustrated comprehensive picture of clinical manifestations of red blood cell disorders.
Download or read book Blood Groups and Red Cell Antigens written by Laura Dean and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Regulation of Tissue Oxygenation Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Download or read book Hemoglobin and red cell structure and function proceedings written by and published by . This book was released on 1972 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemoglobin and the red cell have continued to set a dizzying pace as the objects of research in the two and one-half year interval since the First International Conference on Red Cell Metabolism and Function. Most exciting perhaps, is a beginning molecular attack on sickle cell disease. The story of the interaction of red cell metabolism and oxygen transport has continued to unfold, and we can now infer that patients with hypoxia usually utilize red cell metabolic adjustments to improve oxygenation. This puts the red cell squarely in the center of medical practice, since much of medicine-heart, pulmonary, and blood diseases - deals with inadequate oxygenation. On April 27th through the 29th, 1972, crystallographers, chemists, biochemists, physiologists, geneticists, and physicians from many medical disciplines met in the Towsley Center for Continuing Medical Education at the University of Michigan, Ann Arbor to present new data, to review recent developments, and to try to piece together additional features of the red cell puzzle. The meeting was dedicated to Dr. Francis John Worsley Roughton, Professor Emeritus of Colloid Science, University of Cambridge, England, in recognition of his numerous excellent contributions to the understanding of hemoglobin and red cell function. The program got off to a good start with a paper from M.F. Perutz, Nobel Laureate, on the structure of hemoglobin. Dr. Perutz also key-noted the Conference with a special lecture on heme-heme interaction. A number of fascinating papers were presented on various aspects of hemoglobin, its structure, its interaction with ligands such as oxygen, and its properties under varying conditions. Red cell metabolism was considered, in depth, from many viewpoints, including defects in uremia, interactions with serum phosphorous, male-female differences, the role of catalase, genetic selection for quantitative variation, and mechanisms of glycolytic response to altitude stress and to anemia. As with the first conference, a session was devoted to the continuing assessment of the importance of decline in red cell oxygen transport functional capacity during blood bank storage. A session was also devoted to consideration of carbonic anhydrase and carbon dioxide transport, and the interaction of this area with oxygen transport. A high point of the conference was the session on sickle cell structure and function. Excellent papers were presented on cyanate, including results of some early clinical trials which look promising. A trial with oral urea in sickle cell disease indicating possible usefulness of this approach was presented. The antisickling properties of carbamyl phosphate were also discussed. The present status of prenatal diagnosis of sickle cell disease, and the sickling phenomenon of deer erythrocytes, were other interesting topics. The discussions in the general area of sickle cell disease and the mechanisms by which antisickling agents act were quite interesting because of the diversity and expertise represented in the audience. This volume contains the Proceedings of this second conference. It includes the formal papers and much of the informal discussion after the papers. It represents a compilation of the present state of the art, and the status of current thinking, in the various areas discussed above.
Download or read book Anatomy Physiology written by Lindsay Biga and published by . This book was released on 2019-09-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A version of the OpenStax text
Download or read book Genetics Structure and Function of Blood Cells written by S. R. Hollán and published by Elsevier. This book was released on 2013-10-22 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics, Structure and Function of Blood Cells contains the proceedings of the symposia of the 28th International Congress of Physiology held in Budapest between 13 and 19 of July, 1980. Organized into six parts, this book begins with a discussion on the genetic regulation of hemoglobin synthesis. Parts II and III describe the immunoglobulin receptors and their effectors, and antenatal development of human blood cells. Subsequent parts talk about regulation of differentiation of hemoglobin structure and function and the role of calcium in red cell membrane transport processes. The last part elucidates the structure and function of blood cell membranes.
Download or read book Vertebrate Red Blood Cells written by Mikko Nikinmaa and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the respiratory function of vertebrate red cells. I have defined the phrase "respiratory function" broadly to include, in addition to the actual oxygen and carbon dioxide transport, erythropoiesis, haemoglobin synthesis, red cell structure, the deformability of red cells in circulation, ion and substrate transport across the cell membrane, cellular metabolism, and control of cellular volume and pH. All of these aspects of the red cell function may affect gas transport between the respiratory epithelia and the tissues. Throughout the book, I have tried to relate our current knowledge about the nucleated red cell function to the wealth of information about the function of mammalian red cells. However, whenever possible, I have placed the emphasis on the nucleated red cell function for two reasons. First, the erythro cytes of 90% of vertebrate species are nucleated, and, second, nucleated red cell function has not been reviewed earlier in a single volume. This being the case, I have tried to make the reference list as complete as I could with regard to nucleated red cells. I hope that the approach adopted is useful for both com parative and human physiologists. Many people have contributed to the making of this book directly or in directly. Antti Soivio started me in this field. Prof. Henrik Wallgren has always encouraged fresh scientific ideas in his department. My present ideas of red cell function have been influenced by work carried out with Prof. Roy E.
Download or read book The Red Blood Cell written by Douglas MacN. Surgenor and published by Academic Press. This book was released on 2013-10-22 with total page 783 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Red Blood Cell, Second Edition, Volume II provides a comprehensive treatment and review of basic biomedical knowledge about the circulating, adult red blood cell. This book discusses the transport through red cell membranes; carrier-mediated glucose transport across human red cell membranes; and metabolism of methemoglobin in human erythrocytes. The interaction of oxygen and carbon dioxide with hemoglobin at the molecular level; physiological role of the oxyhemoglobin dissociation curve; hemoglobinopathies; and thalassemia syndromes are also deliberated. This publication likewise covers the red cell genetic polymorphisms; biological life of the red cell; clinical indications for red cells and blood; and biophysical behavior of red cells in suspensions. Other topics include the electrokinetic behavior of red cells; erythrocyte as a biopsy tissue in the evaluation of nutritional status; and knowledge of red cell purine and pyrimidine metabolism coming from the study of human disease. This volume is recommended for students, researchers, teachers, and physicians aiming to acquire knowledge of the red blood cell.
Download or read book Red Cell Structure and Its Breakdown written by Eric Ponder and published by Springer-Verlag. This book was released on 2013-07-02 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pediatric Hematology written by Robert J. Arceci and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric Hematology is a comprehensive and succinct referenced text on the diagnosis and treatment of blood diseases in childhood. It provides a ready source of reference for all the conditions likely to be encountered in day-to-day clinical practice. For each condition, the authors give helpful advice on differential diagnoses and clinical management. This third edition has been extensively updated throughout, in light of recent developments in this rapidly advancing area of medicine. A well established textbook on the diagnosis and treatment of blood disorders in childhood A balanced and cutting edge referenced text on all aspects of diagnosis and treatment Easy to use, practically organized, with essential aspects of biology included within each chapter International editorial and contributor team—representing a wide geographical and chronological range Whether you are an established sub-specialist in pediatric hematology/oncology, a pediatrician, a trainee or nursing specialist, this book will answer all your questions about benign and malignant disorders of the blood in children and young adults.
Download or read book Clinical Methods written by Henry Kenneth Walker and published by Butterworth-Heinemann. This book was released on 1990 with total page 1128 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR
Download or read book Cell Membrane written by Yoshihito Yawata and published by John Wiley & Sons. This book was released on 2006-01-24 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication presents the structure and function of biological membranes to improve the understanding of cells in both normal and pathogenic states. Recently, vast amounts of new information have been accumulated, especially about pathological conditions, and there is now much evidence correlating genotypes and phenotypes in normal and disease states. This book surveys the most recent findings in research on the molecular biology, biochemistry, and genetics of the membranes of human red blood cells.
Download or read book Hemoglobin written by Jay F. Storz and published by Oxford University Press. This book was released on 2018-11-08 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary aim of this book is to provide a synthesis of our current understanding of hemoglobin function and evolution, and to illustrate how research on one particular family of proteins has provided general insights into mechanisms of protein evolution and biochemical adaptation. In doing so, it will also promote an appreciation of how mechanistic insights into protein function can enrich our understanding of how evolution works. Reciprocally, it highlights how approaches in evolutionary genetics (such as phylogenetic comparative methods and ancestral sequence reconstruction) can be brought to bear on questions about the functional evolution of proteins. This treatise on the functional evolution of hemoglobin illustrates how research on a single, well-chosen model system can enhance our investigative acuity and bring key conceptual questions into especially sharp focus.
Download or read book Erythrocyte Structure and Function written by George J. Brewer and published by . This book was released on 1975 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt:
