Download or read book Harmonization of Biological Testing Methodology written by LR. Williams and published by . This book was released on 1985 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latitude provided in many written biological test methods, including ASTM standard practices, is such that different laboratories can produce widely varying test results on the same test materials while in technical compliance with the "method." One obvious solution to this problem is to standardize upon more tightly controlled, less flexible testing procedures. This approach, while widely accepted in the field of chemistry, has been strongly resisted by the biological testing community. This paper presents an alternative approach to achieving comparability of testing data among laboratories while retaining a high degree of flexibility for the individual laboratory. The keys to this approach are (1) the development and routine use of standard reference materials for test system calibration and control, (2) the development of "reference standard methods" that are sufficiently controlled that responses of the test systems to known test materials are predictable and reproducible, and (3) participation in external performance evaluation programs. Recommendations for implementation of a performance-based method evaluation program are offered.
Download or read book Biological Variation written by Callum G. Fraser and published by Amer. Assoc. for Clinical Chemistry. This book was released on 2001 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Harmonization of Methodology written by W. Horwitz and published by . This book was released on 1989 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not long ago, most experimentation dealing with analytical methodology in the physical and biological sciences was conducted within a single laboratory. Method validation by other laboratories was not only considered unnecessary but also detrimental because, in the words of one commentator, "the results are too variable." Within the last two decades, however, largely as a result of the requirements of international environmental and food standards programs, it has become increasingly apparent that a collaborative interlaboratory study is the only way to estimate the systematic and random error characteristics of methods of analysis as they will be performed by the population of laboratories typical of those who will be using the method. To obtain a common basis for measuring the statistical characteristics of analytical methods, representatives of almost two dozen international organizations meeting in Geneva in May 1987 approved by consensus a protocol that will be useful for the design and interpretation of collaborative studies of chemical methods of analysis. Much of this protocol will also be useful for the study of biological measurement methods.
Download or read book Hemostasis and Thrombosis written by Emmanuel J. Favaloro and published by Humana. This book was released on 2018-08-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection thoroughly explores the dynamic and ever-developing field of hemostasis and thrombosis diagnostics and research. After an introductory section covering the basics and preanalytical issues, the book continues with in-depth sections that explore how to get the best outcomes from routine coagulation and specialized hemostasis assays, thrombophilia-related techniques, investigations into bleeding disorders, as well as performance of global assays of hemostasis, and finally post-analytical issues in hemostasis and thrombosis testing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Hemostasis and Thrombosis: Methods and Protocols serves as an ideal resource for researchers and diagnostic laboratories seeking expert guidance and working to identify the best methodologies to pursue hemostasis and thrombosis testing.
Download or read book Aquatic Toxicology and Hazard Assessment written by Rita Comotto Bahner and published by ASTM International. This book was released on 1985 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Selected Water Resources Abstracts written by and published by . This book was released on 1988 with total page 1198 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Microbiology Procedures Handbook written by and published by John Wiley & Sons. This book was released on 2020-08-06 with total page 2954 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the ever-changing needs and responsibilities of the clinical microbiology field, Clinical Microbiology Procedures Handbook, Fourth Edition has been extensively reviewed and updated to present the most prominent procedures in use today. The Clinical Microbiology Procedures Handbook provides step-by-step protocols and descriptions that allow clinical microbiologists and laboratory staff personnel to confidently and accurately perform all analyses, including appropriate quality control recommendations, from the receipt of the specimen through processing, testing, interpretation, presentation of the final report, and subsequent consultation.
Download or read book Selected Water Resources Abstracts written by and published by . This book was released on 1988 with total page 1212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Progress in Standardization of Aquatic Toxicity Tests written by Amadeu Soares and published by CRC Press. This book was released on 1993-06-16 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Standardization of Aquatic Toxicity Tests provides a critical evaluation of the level of standardization achieved by freshwater and marine ecotoxicity tests used to evaluate potential risk of new chemicals and wastewater effluents. Tests at the sub-cellular, individual, laboratory microcosm, and ecosystem levels are presented and critically evaluated. The influence of environmental and genetic heterogeneity on test standardization is also discussed. The book will be an excellent reference for industry professionals, consultants, regulatory officials, and students working in the ecotoxicology field.
Download or read book Healthcare Ethics and Training Concepts Methodologies Tools and Applications written by Management Association, Information Resources and published by IGI Global. This book was released on 2017-03-28 with total page 1545 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of proper ethical systems and education programs is a vital concern in the medical industry. When healthcare professionals are held to the highest moral and training standards, patient care is improved. Healthcare Ethics and Training: Concepts, Methodologies, Tools, and Applications is a comprehensive source of academic research material on methods and techniques for implementing ethical standards and effective education initiatives in clinical settings. Highlighting pivotal perspectives on topics such as e-health, organizational behavior, and patient rights, this multi-volume work is ideally designed for practitioners, upper-level students, professionals, researchers, and academics interested in the latest developments within the healthcare industry.
Download or read book Managing the Patient focused Laboratory written by George D. Lundberg and published by . This book was released on 1975 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Validation of Alternative Methods for Toxicity Testing written by Chantra Eskes and published by Springer. This book was released on 2016-09-26 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcriptomics, and for methods derived from pathway-based concepts in toxicology. Validation of Alternative Methods for Toxicity Testing is divided into two sections, in the first, practical insights are given on the state-of-the-art and on approaches that have resulted in successfully validated and accepted alternative methods. The second section focuses on the evolution of validation principles and practice that are necessary to ensure fit-for-purpose validation that has the greatest impact on international regulatory acceptance of alternative methods. In this context validation needs to keep pace with the considerable scientific advancements being made in toxicology, the availability of sophisticated tools and techniques that can be applied in a variety of ways, and the increasing societal and regulatory demands for better safety assessment. This book will be a useful resource for scientists in the field of toxicology, both from industry and academia, developing new test methods, strategies or techniques, as well as Governmental and regulatory authorities interested in understanding the principles and practicalities of validation of alternative methods for toxicity testing.
Download or read book Harmonization of Leaching Extraction Tests written by L. Heasman and published by Elsevier. This book was released on 1997-06-10 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a unique compilation on the use of leaching/extraction methods in different fields. The use of leaching test methods is increasing in various areas including: waste treatment and disposal; incineration of waste; soil clean-up and reuse of cleaned soil; sludge treatment. This has led to (and may increasingly lead to) the development of a large number of very similar tests in these different fields. However, these developments are taking place with no clear understanding of their mutual relationships. In view of these developments, efforts are needed to harmonize the leaching procedures that could be adapted for different matrices, as well as validate the use of existing tests in other fields. The development of a wide variety of leaching/extraction tests for different matrices is undesirable from a regulatory point of view and undesirable for industry. Clarity in testing is crucial in producer-consumer relations. This collective document will assist in improving the understanding of leaching from a variety of sources and will, where appropriate, help to bring together the approaches used in different technical fields and in different countries.
Download or read book OECD Series on Testing and Assessment Guidance Document on Good In Vitro Method Practices GIVIMP written by OECD and published by OECD Publishing. This book was released on 2018-12-10 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...
Download or read book EPA 540 9 written by and published by . This book was released on 1975-02 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biological Testing Methods written by Washington (State). Department of Ecology. Hazardous Waste Section and published by . This book was released on 1981 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Pharmaceutical Manufacturing Formulations written by Safaraz K. Niazi and published by CRC Press. This book was released on 2016-04-19 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: No other area of regulatory compliance receives more attention and scrutiny by regulatory authorities than the regulation of sterile products, for obvious reasons. With the increasing number of potent products, particularly the new line of small protein products, joining the long list of proven sterile products, the technology of manufacturing ster
