Download or read book Handbook of Immunology and Aging written by Isla Pierce and published by Foster Academics. This book was released on 2019-06-12 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology is a branch of biology concerned with the study of immune systems. Immunological studies have applications in the fields of oncology, organ transplantation, rheumatology, dermatology, etc. The disorders of the immune system can result in immunodeficiency diseases and autoimmune diseases. Immunodeficiency diseases are caused when the immune system fails to provide the adequate immune response. When the immune system attacks its own host's body, it leads to autoimmune diseases, some of which include rheumatoid arthritis, systemic lupus erythematosus, Hashimoto's disease, etc. The gradual accumulation of psychological, physical and social changes in a human being over time constitutes the process of aging. A less efficient immune function is a characteristic of old age. As the immune system weakens progressively with age, the organism becomes unable to fight infections and increasingly incapable of destroying old and neoplastic cells. This eventually leads to death. This book contains some path-breaking studies in immunology and aging. It unfolds the innovative aspects of the relationship between immunology and aging, which will be crucial for the understanding of these areas. The readers would gain knowledge that would broaden their perspective about these fields.
Download or read book CRC Handbook of Immunology in Aging written by and published by . This book was released on 1981 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook on Immunosenescence written by Tamas Fulop and published by Springer Science & Business Media. This book was released on 2009-02-27 with total page 1693 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.
Download or read book The Age of Immunology written by A. David Napier and published by University of Chicago Press. This book was released on 2010-12-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this fascinating and inventive work, A. David Napier argues that the central assumption of immunology—that we survive through the recognition and elimination of non-self—has become a defining concept of the modern age. Tracing this immunological understanding of self and other through an incredibly diverse array of venues, from medical research to legal and military strategies and the electronic revolution, Napier shows how this defensive way of looking at the world not only destroys diversity but also eliminates the possibility of truly engaging difference, thereby impoverishing our culture and foreclosing tremendous opportunities for personal growth. To illustrate these destructive consequences, Napier likens the current craze for embracing diversity and the use of politically correct speech to a cultural potluck to which we each bring different dishes, but at which no one can eat unless they abide by the same rules. Similarly, loaning money to developing nations serves as a tool both to make the peoples in those nations more like us and to maintain them in the nonthreatening status of distant dependents. To break free of the resulting downward spiral of homogenization and self-focus, Napier suggests that we instead adopt a new defining concept based on embryology, in which development and self-growth take place through a process of incorporation and transformation. In this effort he suggests that we have much to learn from non-Western peoples, such as the Balinese, whose ritual practices require them to take on the considerable risk of injecting into their selves the potential dangers of otherness—and in so doing ultimately strengthen themselves as well as their society. The Age of Immunology, with its combination of philosophy, history, and cultural inquiry, will be seen as a manifesto for a new age and a new way of thinking about the world and our place in it.
Download or read book Handbook of Human Stress and Immunity written by Ronald Glaser and published by Academic Press. This book was released on 2014-06-28 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1964, George Solomon coined the term psychoneuroimmunology. In the intervening 30 years, this term has emerged into a dynamic field of study which investigates the unique interactions between the nervous, endocrine, and immune systems. The Handbook of Human Stress and Immunity is a comprehensive reference for this dynamic new field. Focusing on how stressors impact the central nervous system and the resulting changes in immune responses, the Handbook is the first to describehow stress specifically affects human immune systems. It discusses how stress generally makes people more susceptible to infection, how personal support systems can counteract the physiological effects of stress, and how stress, or lack of stress, affects the aging process. Chapters are authored by the leading names in the field and cover such diseases as autoimmune disease, viral pathogenesis, herpes, HIV, and AIDS.
Download or read book Immunology of Aging written by Ahmad Massoud and published by Springer. This book was released on 2016-10-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidity of scientific progress over the last few years guarantees the utility of this new collection of state-of-the-art reviews on the immunology of aging, which is the result of extensive collaboration of more than sixty of the greatest thinkers and scholars in the field, in cooperation with a number of junior colleagues. The book summarizes current knowledge on the cellular and molecular aspects of the aging immune system and their clinical relevance, providing insights into the effects of the aging process on susceptibilities to those diseases most common among elders. The retrieval strategies used to slow down the decline in the immune system in the elderly are another subject detailed extensively. By providing a broad overview of immunosenescence and its consequences, as well as their potential modulation, this book will fill a gap in a timely manner. It will be of value to all immunologists, whether novice or experienced, as well as geriatricians and epidemiologists.
Download or read book Handbook of the Biology of Aging written by Edward L. Schneider and published by Academic Press. This book was released on 2013-10-22 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of The Biology of Aging, Third Edition provides a general overview to a wide scientific audience of some of the most important topics in biomedical gerontology. The book discusses methodologies for biological aging studies and on animal models. Protein modifications with aging, special senses, circadian rhythms, and the adrenocortical axis are tacked in the book as well. Gerontologists, psychologists, health care professionals, and graduate students will find the book useful.
Download or read book Handbook of Aging and the Social Sciences written by Linda George and published by Academic Press. This book was released on 2010-11-26 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Aging and the Social Sciences, Seventh Edition, provides extensive reviews and critical evaluations of research on the social aspects of aging. It also makes available major references and identifies high-priority topics for future research. The book is organized into four parts. Part 1 reviews developments in the field of age and the life course (ALC) studies and presents guidelines on conducting cohort analysis. Part 2 covers the demographic aspects of aging; longevity trends; disability and aging; and stratification and inequality research. Part 3 includes chapters that examine socioeconomic position and racial/ethnic disparities in health at older ages; the role of social factors in the distribution, antecedents, and consequences of depression; and aspects of private wealth transfers and the changing nature of family gift-giving. Part 4 deals with pension reform in Europe; the political activities of older Americans; the future of retirement security; and gender differences in old age. The Handbook is intended for researchers, professional practitioners, and students in the field of aging. It can also serve as a basic reference tool for scholars, professionals, and others who are not presently engaged in research and practice directly focused on aging and the aged. - Contains all the main areas of social science gerontological research in one volume - Begins with a section on theory and methods - Edited by one of the fathers of gerontology (Binstock) and contributors represent top scholars in gerontology
Download or read book Handbook of the Biology of Aging written by Nicolas Musi and published by Academic Press. This book was released on 2015-08-20 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of ‘big data’ approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to aging related problems. The book includes discussions on longevity pathways and interventions that modulate aging, innovative new tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, new strategies to pharmacologically modulate the mTOR pathway to delay aging, the importance of sirtuins and the hypoxic response in aging, and how various pathways interact within the context of aging as a complex genetic trait, amongst others. Covers the key areas in biological gerontology research in one volume, with an 80% update from the previous edition Edited by Matt Kaeberlein and George Martin, highly respected voices and researchers within the biology of aging discipline Assists basic researchers in keeping abreast of research and clinical findings outside their subdiscipline Presents information that will help medical, behavioral, and social gerontologists in understanding what basic scientists and clinicians are discovering New chapters on genetics, evolutionary biology, bone aging, and epigenetic control Provides a close examination of the diverse research being conducted today in the study of the biology of aging, detailing recent breakthroughs and potential new directions
Download or read book Stress Immunity and Aging written by E. L. Cooper and published by CRC Press. This book was released on 2020-07-24 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains two personal reminiscences of historical importance to research on stress and infectious disease. It deals with perspectives on immunity, aging, and disease and the prospects for immunorestoration in the treatment of immunodeficiency arising from aging and stress.
Download or read book Immunology and Aging written by Takashi Makinodan and published by Springer. This book was released on 1977-05 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the classic sense, immunity is the ability of an organism to resist disease. On the one hand, we must distinguish between age and disease; on the other hand, the interaction between them is of considerable theoretical and practical interest. To the gerontologic research community, therefore, immunity also becomes the ability of an organism to resist age. Were the immune and other protective systems of the body able to maintain themselves over the course of time, and if there were no degradation related to age, the everyday loss of energy and vitality that occurs in the lives of older people as a consequence of viruses, arthritis, and other debilitating circumstances would be greatly lessened. The objective of gerontologists is not just to extend the life span but rather to improve the vigor, health, and quality oflife. To date, we have not developed a single index to measure immunity that is of use clinically in the evaluation of older people and of their immunologic compe tence. It may not be surprising that just such a clinical index may be available in the not-too-distant future. We can also look forward to the assembling of a greater body of information explaining how and why the immune system fails with age while, paradoxically, the incidence of autoimmune diseases increases with age. It is this latter phenomenon that may playa part in a wide range of chronic diseases from rheumatoid arthritis to senile dementia.
Download or read book Handbook of Human Immunology written by Mary S. Leffell and published by CRC Press. This book was released on 1997-04-10 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining basic explanations of laboratory tests with 115 tables full of reference data and applications, the Handbook of Human Immunology provides practicing clinicians with a current, complete guide to molecular immunology. Introductory chapters overview the molecular basis of immune responses and immunological disorders, focusing on the role of cell receptors, accessory molecules, and cytokines in these processes. Emphasis is placed on immunological parameters that are clinically useful. The basic principles underlying assays of the immune system are discussed, and the book stresses the application and interpretation of immune tests. Comprehensive coverage is given to immunoglobulins and their age-dependent concentration. Cellular immunology is discussed from the perspectives of lymphocyte functional parameters, as well as through immunophenotyping of lymphocytes and other leukocytes. Both serological and molecular diagnosis of infectious diseases are reviewed. The Handbook of Human Immunology contains up-to-date information on exciting developments in immunogenetics, covering the application of T-cell receptor genes and the HLA alleles in disease associations and transplantation.
Download or read book Handbook of Immunosenescence written by Tamas Fulop and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: ZImmunosenescencey is an imprecise term used to describe deleterious age-associated changes to immune parameters observed in all mammals studied so far. It represents a rapidly progressing science in the aging field, with a vertiginous volume of new data, knowledge and concepts concerning these changes. Indeed, during the almost 10 years that have passed since the first edition of this Handbook, a wealth of additional information has emerged from animal models and also from increasingly available human data. Numerous new aspects of the immune changes with aging have emerged, while others became less prominent. The application of the new multi-zomicsy techniques in immunology have revolutionized our molecular understanding of basic immune mechanisms. The extended and revisited concept of Inflamm-aging sheds a new light on the intricate relationships among immunosenescence and inflamm-aging. The new concept of inflamm-aging integrates different emerging experimental data such as those pertaining to the senescence-associated secretory phenotype and responses to damage. zGerosciencey is emphasising the role of immune changes during life in all manner of age-related chronic diseases such as cancer and neurodegenerative disorders. The field is poised to be in a position to translate these accumulated data into the clinical setting via a better understanding of the contribution of immunosenescence to age-associated pathologies, and their prevention by appropriate interventions. This new edition of the Handbook seeks to encompass the current state of our knowledge on the multitude of those changes to immunity related to aging, with contributions from experts in both basic research and clinical areas. This book therefore considers methods and models for studying immunosenescence; cellular immunosenescence of T cells, B cells, neutrophils, antigen presenting cells, NK, NKT and stem cells; genetics; mechanisms including receptors and signal transduction; mitochondria; proteasome; cytokines; neuro-endocrine-immune networks; inflammation; thymus; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; modulation by nutrition, microbiome, lipids, vaccination and the burning question zcan interventions to influence immunosenescence be realistically proposed based on our current state of knowledge?y.
Download or read book The Wiley Blackwell Handbook of Psychoneuroimmunology written by Alexander W. Kusnecov and published by John Wiley & Sons. This book was released on 2013-12-31 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive resource details the history, methodology and development of research into psychoneuroimmunology, balancing it with meticulous coverage of both the clinical aspects and practical applications of the subject. A much-needed reference including overviews of key advances in the field Discusses how psychoneuroimmunological research is conceived and executed Includes contributions from a wealth of experts in the field Forward by Robert Ader and Nicholas Cohen, founders of the discipline Authoritative and interdisciplinary in scope - integrating biological and behavioral science
Download or read book Autophagy Cancer Other Pathologies Inflammation Immunity Infection and Aging written by M. A. Hayat and published by Academic Press. This book was released on 2016-12-28 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is an eleven volume series that discusses in detail all aspects of autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. This series discusses the characterization of autophagosome-enriched vaccines and its efficacy in cancer immunotherapy. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to cellular processes while also inciting researchers to explore their potentially important connections. Presents the most advanced information regarding the role of the autophagic system in life and death Examines whether autophagy acts fundamentally as a cell survivor or cell death pathway or both Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation Features recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, including atherosclerosis and CNS tumors, and their development and treatment Includes chapters authored by leaders in the field around the globe—the broadest, most expert coverage available
Download or read book The Ageing Immune System and Health written by Valquiria Bueno and published by Springer. This book was released on 2016-10-03 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity. Our focus is on the main changes in immune system cells and their products occurring during the ageing process and the possible consequences for health and disease. This includes: discussion of the modulatory and/or suppressive mechanisms associated with the alterations in T regulatory cells, B regulatory cells and Myeloid Derived Suppressor cells; changes in the immune system observed in chronic neurodegenerative diseases, cancer, lung disease and frailty will also be discussed. Most importantly we provide recent literature information about possible interventions (focusing on physical activity) that could alleviate the negative effects of immunosenescence. The Ageing Immune System and Health is a comprehensive guide on the field intended to all physicians, researchers, professors and students interested on relationship between immune system, ageing and health.
Download or read book HDBK IMMUNOLOGY OF AGING written by Marguerite M. B. Kay and published by Springer. This book was released on 1981-10-27 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
