Download or read book Gut Peptides written by John H. Walsh and published by Raven Press (ID). This book was released on 1994 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a comprehensive approach to gastrointestinal hormones, for clinicians and scientists who are interested in hormonal regulation of the gastrointestinal tract. The first section discusses general issues related to peptides as messengers, including receptors and signal transduction and control of gene expression. The second section presents the biochemical and physiological features of the gastrointestinal hormones and neuropeptides. The third section integrates these peptides into physiological and pathophysiological regulatory pathways of the gut. Annotation copyright by Book News, Inc., Portland, OR
Download or read book Gut Hormones written by Stephen Robert Bloom and published by . This book was released on 1981 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gastrointestinal Regulatory Peptides written by David R. Brown and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive and conceptual one-volume treatment of this field available and the first to emphasize the cellular and molecular aspects of gut peptide biology. Authored by an array of internationally distinguished scientists, it deals with issues of peptide localization and biosynthesis in gastrointestinal cells, mechanisms of peptide release and inactivation and the nature of peptide receptors. The breadth and readability make it an invaluable reference source for scientists in all disciplines interested in any aspect of brain-gut peptides.
Download or read book Regulation of Gastrointestinal Mucosal Growth written by Rao N. Jaladanki and published by Biota Publishing. This book was released on 2016-11-30 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian gastrointestinal mucosa is a rapidly self-renewing tissue in the body, and its homeostasis is preserved through the strict regulation of epithelial cell proliferation, growth arrest, and apoptosis. The control of the growth of gastrointestinal mucosa is unique and, compared with most other tissue in the body, complex. Mucosal growth is regulated by the same hormones that alter metabolism in other tissues, but the gastrointestinal mucosa also responds to host events triggered by the ingestion and presence of food within the digestive tract. These gut hormones and peptides regulate the growth of the exocrine pancreas, gallbladder epithelium, and the mucosa of the oxyntic gland region of the stomach and the small and large intestines. Luminal factors, including nutrients or other dietary factors, secretions, and microbes that occur within the lumen and distribute over a proximal-to-distal gradient, are also crucial for maintenance of normal gut mucosal regeneration and could explain the villous-height-crypt-depth gradient and variety of adaptation, since these factors are diluted, absorbed, and destroyed as they pass down the digestive tract. Recently, intestinal stem cells, cellular polyamines, and noncoding RNAs are shown to play an important role in the regulation of gastrointestinal mucosal growth under physiological and various pathological conditions. In this book, we highlight key issues and factors that control gastrointestinal mucosal growth and homeostasis, with special emphasis on the mechanisms through which epithelial renewal and apoptosis are regulated at the cellular and molecular levels.
Download or read book Peptide Transport in Bacteria and Mammalian Gut written by Katherine Elliott and published by John Wiley & Sons. This book was released on 2009-09-16 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Download or read book Gastrointestinal Endocrinology written by Jr. Greeley and published by Springer Science & Business Media. This book was released on 1998-12-31 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading clinical and basic science researchers present the latest molecular and cellular findings on key gut peptides, illuminating their physiology and pathophysiology, as well as highlighting the regulatory mechanisms underlying their action in the intestinal tract. The book focuses on gut peptide physiology and receptor pharmacology, gut processing and receptor biology, and on regulatory mechanisms in the gut, including pancreatic feedback mechanisms. Also included are chapters on the trophic effects of gut peptides on GI and pancreatic cancer; the regulation of gut peptide gene expression; and gastric secretion, especially in diseased states.
Download or read book Gastrointestinal Regulatory Peptides written by David R Brown and published by . This book was released on 1993-03-26 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Brain gut Peptides and Reproductive Function written by Charles D. Barnes and published by CRC Press. This book was released on 2020-07-24 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book elucidates the role of brain-gut peptides in neuroendocrine regulation for understanding how these peptides interact with the reproductive neuroendocrine axis and for developing novel therapeutic agents for fertility or contraceptive therapies.
Download or read book Gut brain Peptides in the New Millennium written by John H. Walsh and published by Lippincott Williams & Wilkins. This book was released on 2002 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. John Walsh was a towering figure in gastroenterology and had a profound impact on the study of gut-brain peptides in health and diseases. This commemorative book contains a collection of papers by former trainees and collaborators, which reflect the wide array of investigations to which Dr. Walsh brought his keen intellectual influence and support
Download or read book Antimicrobial Peptides in Gastrointestinal Diseases written by Chi Hin Cho and published by Academic Press. This book was released on 2018-06-06 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only in the context of GI diseases, but also for similar pathologies in other organs. AMPs are key to the regulation of human microbiome and second line defence in the GI mucosa, prevent colonization of pathogens and modulation of innate response to invading pathogens, and modify immunological reactions during inflammatory processes and oncogenic development in the GI mucosa. More importantly, AMPs possess diversified anti-microbial actions against various infectious diseases in the GI tract. With these physiological functions and pharmacological actions, AMPs have significant potential as therapeutic agents for the treatment of inflammation, cancer and further infection in the GI tract. Provides an overview of AMPs, particularly cathelicidin and defensin, in different diseases Covers inflammation and ulcer repair in the stomach and colon and carcinogenesis in the GI tract Presents AMP information and knowledge in a concise manner Gives useful information on all aspects of AMPs Promotes research on AMPs and their development as drugs, from bench, to clinical application
Download or read book Gut Regulatory Peptides written by Enrique Blázquez and published by S. Karger AG (Switzerland). This book was released on 1987 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Comparative Physiology of Regulatory Peptides written by Susanne Holmgren and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strictly speaking, the term regulatory peptides may include any peptide which has a regulatory function in any organism. In recent years, how ever, the term has come to mean those originally classified as brain-gut peptides. The peptides initially defined as those belonging to the brain gut axis had a dual location in neurones of the brain and endocrine cells of the gut. We now include a number of neuropeptides found in the autonomic nervous system of the gut, the cardiovascular system and other systems. To many scientists comparative physiology means comparison of the mechanisms of certain functions in the rat, the guinea-pig, the cat and maybe some other mammal. If the philosophy is that man is the centre of the universe and other mammals can be used as 'models' of man, this may well be the most useful way to study the functions of the human being, without actually chopping somebody up. However, with a some what wider perspective on life, it is easy to see the importance of a full understanding of the function of all living organisms, in its own right as well as a link in the evolution towards individuals able to survive and reproduce in very different environments. The importance of com parative studies in all living organisms cannot be emphasized too much. It has been the ambition with this book to treat all animals as equally important.
Download or read book Peptidomics written by Mikhail Soloviev and published by John Wiley & Sons. This book was released on 2007-12-21 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive guide to peptidomics- a hands-on lab reference The first truly comprehensive book about peptidomics for protein and peptide analysis, this reference provides a detailed description of the hows and whys of peptidomics and how the techniques have evolved. With chapters contributed by leading experts, it covers naturally occurring peptides, peptidomics methods and new developments, and the peptidomics approach to biomarker discovery. Explaining both the principles and the applications, Peptidomics: Methods and Applications: * Features examples of applications in diverse fields, including pharmaceutical science, toxicity biomarkers, and neuroscience * Details the successful peptidomic analyses of biological material ranging from plants to mammals * Describes a cross section of analytical techniques, including traditional methodologies, emerging trends, and new techniques for high throughput approaches An enlightening reference for experienced professionals, this book is sufficiently detailed to serve as a step-by-step guide for beginning researchers and an excellent resource for students taking biotechnology and proteomics courses. It is an invaluable reference for protein chemists and biochemists, professionals and researchers in drug and biopharmaceutical development, analytical and bioanalytical chemists, toxicologists, and others.
Download or read book Management of Pancreatic Neuroendocrine Tumors written by Joseph R. Pisegna and published by Springer. This book was released on 2014-10-15 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with a multidisciplinary approach that is state of the art and reflects input from the European Neuroendocrine Tumor Society and the North American Neuroendocrine Tumor Society. In particular, the text focuses on the pathophysiology of neuroendocrine tumors and includes a comprehensive review of the most recent developments in understanding the complex hormone and receptor signaling that is important for the future development of potent pharmacological treatments. The volume reviews the pathological grading and staging systems providing useful clinical information for the treating clinician as well as a useful reference for pathologists. The clinical management of neuroendocrine tumors is reviewed enabling the treating physician to understand the diagnostic approaches to differentiating the various types of neuroendocrine tumors. In addition, the treatments are reviewed in great detail and include novel radiological, surgical, and chemotherapeutic approaches. The reader will utilize this book as both a comprehensive and quick reference guide through the use of diagnostic and treatment algorithms. Written by international experts in their particular field of study, Management of Pancreatic Neuroendocrine Tumors will be of great value to medical oncologists, endocrinologists, gastroenterologists, pathologists, surgeons, and diagnostic and interventional radiologists.
Download or read book Relationships Among the Brain the Digestive System and Eating Behavior written by Institute of Medicine and published by National Academies Press. This book was released on 2015-02-27 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: On July 9-10, 2014, the Institute of Medicine's Food Forum hosted a public workshop to explore emerging and rapidly developing research on relationships among the brain, the digestive system, and eating behavior. Drawing on expertise from the fields of nutrition and food science, animal and human physiology and behavior, and psychology and psychiatry as well as related fields, the purpose of the workshop was to (1) review current knowledge on the relationship between the brain and eating behavior, explore the interaction between the brain and the digestive system, and consider what is known about the brain's role in eating patterns and consumer choice; (2) evaluate current methods used to determine the impact of food on brain activity and eating behavior; and (3) identify gaps in knowledge and articulate a theoretical framework for future research. Relationships among the Brain, the Digestive System, and Eating Behavior summarizes the presentations and discussion of the workshop.
Download or read book The Insulinotropic Gut Hormone Glucagon like Peptide 1 written by Hans-Christoph Fehmann and published by Karger Medical and Scientific Publishers. This book was released on 1997 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glucagon-like peptide-1 (GLP-1) is a promising new therapeutic tool for the treatment of diabetes. Since the first reports describing its potent insulinotropic activity were published about a decade ago, knowledge of the incretin hormones, and GLP-1 in particular, has increased significantly. This timely volume summarizes what is now known about the molecular biology, physiology and pharmacology of GLP-1. Thorough coverage is given to the physiology of the hormone, including its generation, release and actions at pancreatic and extrapancreatic tissues. The intracellular mechanisms of GLP-1 are also described in detail. Discussion of the molecular biology includes the structure and functions of the genes coding for proglucagon and the GLP-1 receptor. A special feature of the book is the clinical information provided which includes data on the expression and release of GLP-1 and its potential use as a therapeutic agent for diabetes. Presenting the results of exciting new research, this book will be a valuable reference for endocrinologists, gastroenterologists, pharmacologists, physiologists and biochemists interested in this important hormone.
Download or read book Satiation written by Gerard P. Smith and published by Oxford University Press, USA. This book was released on 1998 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume on the neurophysiological mechanisms of satiation deals with the stimuli at sites in the mouth, stomach and intestine that initiative this negative-feedback process provides a detailed behavioural analysis, and reviews the satiating effects of cholecystokinin, bombesin-like peptides lucogen and insulin as well as brain serotonin.
