Download or read book Toxicology of Glutathione Transferases written by Yogesh C. Awasthi and published by CRC Press. This book was released on 2006-07-27 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of Glutathione S-Transferase (GST) or Glutathione transferase, studies have probed important questions about its pharmacological and physiological significance. Toxicology of Glutathione Transferases is the only text that details the methods used in GST research. With chapters written by experts who have been involved in

Download or read book Structure and Function of Glutathione S Transferases written by Kenneth D. Tew and published by CRC Press. This book was released on 1993-08-26 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structure and Function of Glutathione S-Transferases provides some of the latest information available on a variety of structural and functional components of glutathione S-transferases, a family of isozymes involved in many endogenous and exogenous functions in cells. Molecular studies presented in the book focus on the regulation of these enzymes and identify important response elements. X-ray crystallographic structures show detailed information on the structural aspects of these proteins. Metabolism of a number of carcinogens and drugs is covered in detail, and the role that these enzymes play in governing drug resistance at the preclinical and clinical levels is discussed. The book will be excellent for biochemists, pharmacologists, oncologists, experimental therapeutic specialists, and others interested in glutathione S-transferases.

Download or read book Glutathione Transferases and Gamma Glutamyl Transpeptidases written by Helmut Sies and published by Gulf Professional Publishing. This book was released on 2005-11-22 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focuses on particular aspects of the so-called Phase II of drug detoxication, which has important ramifications for endogenous metabolism and nutrition. This volume on glutathione transferases and gamma-glutamyl transpeptidases serves to bring together methods and concepts in a rapidly developing field of cell and systems biology.

Download or read book Glutathione S Transferases written by Gerard J. Mulder and published by CRC Press. This book was released on 1996-05-23 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glutathione s-transferases (GSTs) constitute the most important enzymes protecting human and many other organisms from potentially toxic chemicals, including drugs and carcinogens. This book reviews scientific developments in research of this enzyme.

Download or read book Plant Glutathione Transferases Diverse Multi Tasking Enzymes with Yet to Be Discovered Functions written by Jolán Csiszár and published by Frontiers Media SA. This book was released on 2019-12-05 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Science of Flavonoids written by Erich Grotewold and published by Springer Science & Business Media. This book was released on 2008 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the only book of its kind to provide an overview of the science of flavonoids in plants.

Download or read book Glutathione S transferases written by Igor Azevedo Silva and published by Nova Science Publishers. This book was released on 2020 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Glutathione S-transferase (GST) isoenzymes are an important superfamily of proteins that are present in homodimer or heterodimer structures. The isoenzymes included in this superfamily are involved in endobiotic and xenobiotic detoxification systems in animals, plants and microorganisms. This compilation focuses on the importance of functional aspects of polymorphic variants in different populations so the risk genotypes can be identified as indicators of disease susceptibility. Genetic studies will help to develop prognostic biomarkers for early prediction and risk assessment in patients, and enable clinicians to develop personalized treatment regimens. The authors examine the different kinds of reactive oxygen species and reactive species which act as carcinogens and cause damage to DNA, RNA, proteins and lipids, thereby resulting in human disease like bladder cancer. Also reviewed is the association of GST's common genetic variants with the development of infertility (failure to establish a clinical pregnancy after 12 months of regular, unprotected sexual intercourse) in women and in men"--

Download or read book The Significance of Glutathione S transferases in Biochemical Toxicology written by Inga Jakobson and published by . This book was released on 1979 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Enzyme Systems that Metabolise Drugs and Other Xenobiotics written by Costas Ioannides and published by John Wiley & Sons. This book was released on 2002 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work focuses on the enzyme systems that participate in the metabolism of chemicals and other xenobiotics, with emphasis being placed on drug metabolism. Each chapter focuses on a specific enzyme system.

Download or read book Glutathione S transferases and Carcinogenesis written by Timothy John Mantle and published by Taylor & Francis Group. This book was released on 1987 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Herbicides and Their Mechanisms of Action written by Andrew H Cobb and published by Blackwell. This book was released on 2000-12-18 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Herbicides and their Mechanisms of Action highlights issues in herbicide selectivity. Developed with the input of authors from both academia and industry, this volume delivers a comprehensive and up-to-date treatment of the operation of the selectivity mechanisms of herbicides. Even more, the book discusses real-world effects of herbicides, and the results herbicides bring to bear on the environment. The authors emphasize applied aspects of the subject and concentrate on the developments of the last decade, making the book both practical and timely. With the wide variety of herbicides now available for the selective control of weed growth, it is imperative that scientists acquire a detailed understanding of the scientific bases of these herbicides. Indeed, the most recently developed herbicides work by inhibiting the enzyme systems of specific herbs, thereby retarding the growth of those herbs. For maximum effectiveness it becomes crucial that the active ingredients of these herbicides be efficiently delivered on the desired targets. Providing a state-of-the-art appraisal of this important subject, Herbicides and their Mechanisms of Action is the ideal resource for virtually all researchers and professionals involved in the development, administration, and regulation of herbicides.

Download or read book Microsomal Glutathione Transferase written by Ralf Morgenstern and published by . This book was released on 1983 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Glutathione S transferases and Drug Resistance written by John D. Hayes and published by Taylor & Francis Group. This book was released on 1990 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: The proceedings of the 3rd International GST Conference held at the Royal College of Physicians, Edinburgh, on 20-30 August 1989. The conference was divided into five sessions - enzymology, toxication, control of expression, drug resistance and clinical applications of GST.

Download or read book Glutathione Transferases in Rat and Mouse Tissues written by Helgi Jensson and published by . This book was released on 1986 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Glutathione Conjugation written by Helmut Sies and published by . This book was released on 1988 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies on Hepatic Glutathione Transferases from Rat and Man written by Margareta Warholm and published by . This book was released on 1983 with total page 67 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Toxicology of Organophosphate and Carbamate Compounds written by Ramesh C Gupta and published by Academic Press. This book was released on 2011-04-28 with total page 781 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. Describes everything you need to know about Organophosphates and Carbamates Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis Provides in vitro and in vivo models for neurotoxicity testing Integrates knowledge of studies in lab animals and humans Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues Describes management of Anticholinesterase poisoning in humans