Download or read book Glial Cells Managers of Neuro immunity written by Carlos Barcia and published by Frontiers Media SA. This book was released on 2016-05-30 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune responses within the brain are still scarcely explored. Nerve tissue damage is accompanied by the activation of glial cells, primarily microglia and astroglia, and such activation is responsible for the release of cytokines and chemokines that maintain the local inflammatory response and actively recruit lymphocytes and monocytes to the damaged areas. Theoretically, these responses are designed to repair the brain damage. However, alterations, or a chronic perpetuation of these responses may underlie a number of neuro-pathologies. It is thought that each inflammatory scenario within the brain have a specific biochemical footprint characterized by the release of determined cytokines, chemokines and growing factors able to define particular immunological responses. Alongside, glial cells transform their cell body, become larger and develop higher number of branches adopting an active morphological phenotype. These changes are related with the search of interactions with other cells, such as bystander resident cells of the brain parenchyma, but also cells homing from the blood stream. In this process, microglia and astrocytes communicates with other cells by the formation of specific intercellular connections that are still poorly understood. These interactions are complex and entail the arrangement of cytoskeletal compounds, secretory and phagocytic domains. In this particular crosstalk there is a two-way communication in which glial cells and target cells come together establishing interfaces with specific information exchange. This way, glial cells orchestrate the particular response recruiting cellular subsets within the central nervous system and organizing the resolution of the brain damage. In this Frontiers Research Topic, we compile a selection of articles unfolding diverse aspects of glial-derived inflammation, focused on neurodegenerative diseases and other nervous system disorders, with special emphasis on microglia/macrophages as leading actors managing neuro-immunity.

Download or read book Glial Cells Managers of Neuro immunity written by and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune responses within the brain are still scarcely explored. Nerve tissue damage is accompanied by the activation of glial cells, primarily microglia and astroglia, and such activation is responsible for the release of cytokines and chemokines that maintain the local inflammatory response and actively recruit lymphocytes and monocytes to the damaged areas. Theoretically, these responses are designed to repair the brain damage. However, alterations, or a chronic perpetuation of these responses may underlie a number of neuro-pathologies. It is thought that each inflammatory scenario within the brain have a specific biochemical footprint characterized by the release of determined cytokines, chemokines and growing factors able to define particular immunological responses. Alongside, glial cells transform their cell body, become larger and develop higher number of branches adopting an active morphological phenotype. These changes are related with the search of interactions with other cells, such as bystander resident cells of the brain parenchyma, but also cells homing from the blood stream. In this process, microglia and astrocytes communicates with other cells by the formation of specific intercellular connections that are still poorly understood. These interactions are complex and entail the arrangement of cytoskeletal compounds, secretory and phagocytic domains. In this particular crosstalk there is a two-way communication in which glial cells and target cells come together establishing interfaces with specific information exchange. This way, glial cells orchestrate the particular response recruiting cellular subsets within the central nervous system and organizing the resolution of the brain damage. In this Frontiers Research Topic, we compile a selection of articles unfolding diverse aspects of glial-derived inflammation, focused on neurodegenerative diseases and other nervous system disorders, with special emphasis on microglia/macrophages as leading actors managing neuro-immunity.

Download or read book Management of Dysregulated Immune Response in the Critically Ill written by Zsolt Molnar and published by Springer Nature. This book was released on 2023-03-11 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new term introduced by the Sepsis-3 definitions in 2016. In contrast to systemic inflammatory response syndrome (SIRS) that has been used for nearly 30 years, this is a fundamentally new concept, which requires some sort of a paradigm shift in the way of thinking of critical care physicians. This change obviously requires time and after 5 years, time is ripe to summarize the knowledge in the form of a comprehensive book. The book is split in 4 sections. In the first one, the host immune response is explained in 11 chapters, followed by the next part, summarizing the possible tools for assessment at the bedside. The third and the fourth parts focus on the effects of dysregulated immune response on vital organ function and on the possible ways of immunomodulation. Written by internationally acclaimed experts of the field, the book is of value for all those intensivists and allied professionals working in ICUs.

Download or read book Diagnosis and Management of Head and Face Pain written by James Y. Suen and published by Springer. This book was released on 2018-07-20 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is a comprehensive guide to the evaluation of patients with head and face pain. It is a resource for any physician or dentist to properly diagnosis and to learn the options for treating head and face pain, as well as know when to refer a patient to a specialist and how to identify which specialist is needed. It discusses the basic anatomy, etiology, and pathophysiology of head and face pain, classification guidelines for treatment, and clinical case examples. Additional chapters on nerve blocks, nerve stimulators, radiosurgery, microvascular decompression, Botox, and alternative and complementary medicine are also included. Diagnosis and Management of Head and Face Pain will be an invaluable resource for otolaryngologists, family physicians, oral surgeons, dentists, neurologists, neurosurgeons, pain specialists, and patients who suffer from head and face pain.

Download or read book Clinical Pain Management Acute Pain written by Pamela Macintyre and published by CRC Press. This book was released on 2008-09-26 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute Pain brings coverage of this diverse area together in a single comprehensive clinical reference, from the basic mechanisms underlying the development of acute pain, to the various treatments that can be applied to control it in different clinical settings. Much expanded in this second edition, the volume reflects the huge advances that contin

Download or read book Strengthening School Counselor Advocacy and Practice for Important Populations and Difficult Topics written by Rausch, Meredith A. and published by IGI Global. This book was released on 2021-01-29 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: School counselors often struggle to feel confident in delivering effective assistance to students due to a variety of reasons that currently do not have enough research or information developed. This leads to a struggle for counselors to adequately address tough and relevant issues. With these issues remaining unaddressed, or addressed less effectively, there is a concern that school counselors cannot mitigate these issues due to not being adequately informed. This can lead to a lifetime of consequences for students. Strengthening School Counselor Advocacy and Practice for Important Populations and Difficult Topics presents emerging research that seek to answer the tough and often unaddressed questions, target present-day issues of student populations, and prepare school counselors to feel confident and competent in their counseling and advocacy practice. These chapters, using the newest information available, will address these concerns and provide the best counseling work possible for underserved populations. While covering research on counseling for students with chronic illnesses, mixed-statuses, family issues, minority students, LGBTQ+ youth, and more, this book is ideal for school counselors, counseling educators, practitioners, stakeholders, researchers, academicians, and students who are interested in school counseling and meeting the needs of diverse and important populations of students.

Download or read book Core Curriculum for Pain Management Nursing E Book written by Aspmn and published by Elsevier Health Sciences. This book was released on 2024-10-13 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prepare for the nurse's role in assessing and managing pain! Core Curriculum for Pain Management Nursing, 4th Edition uses an easy-to-read outline format to cover the entire scope of pain management. Written by the American Society of Pain Management Nurses (ASPMN(R), the leading nursing organization in pain management), this review begins with foundational concepts and follows with guidelines and tools for effective pain assessment. Coverage of evidence-based pain management strategies and therapies is included for all patient types and ages. Updated to reflect current best practices in nursing, this book provides an excellent review for the ASPMN(R) pain management certification exam and the RN-BC credentialing exam. Content written by ASPMN(R) ensures that information includes the latest in education, research, standards, and practice, as well as a thorough review for the ASPMN(R) certification exam and the RN-BC credentialing exam.. Both pharmacologic and non-pharmacologic methods of pain management are described. Comprehensive coverage includes adult, pediatric, and geriatric patients along with key subsets of patients such as those who have concomitant addiction, those who have cancer, and those who are under sedation for a procedure. Wide-ranging content includes disparities in pain management, the roles of the clinical nurse specialist as well as the nurse practitioner, theories of pain management, the use of research, gender differences in how men and women respond to pain and analgesia, and the effect of depression on pain perception and management. Strong nursing focus provides guidelines for the nurse's role in pain management and in improving the quality of patient care. Easy-to-read outline format makes this book a quick and accessible reference. NEW! Updated content includes the latest changes in clinical practice including pharmacologic and non-pharmacologic pain interventions, integrative and complementary therapies, and the current ANA scope and standards of practice. NEW! Revised chapters include Mental Health Disorders and Pain and Managing Pain in the Context of Substance Use Disorder. NEW! Cannabis Use in Pain Management chapter is added to this edition. NEW! Reorganized content better highlights the complexity of assessment and management of pain. NEW two-color design, illustrations, and summary tables are added throughout the book, making difficult concepts easier to understand and remember.

Download or read book Diagnosis Management of Neurological Disorders written by U K Misra and published by Wolters kluwer india Pvt Ltd. This book was released on 2011-01-01 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an authoritative exposition of the clinical presentation, diagnosis and treatment of neurological disorders. Covering both infectious and non-infectious disorders, the book specially emphasizes the regional variations in the epidemiology, manifestation and management of these disorders in tropical and resource-limited countries.

Download or read book Enteric Glia written by Brian D. Gulbransen and published by Biota Publishing. This book was released on 2014-07-01 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography

Download or read book Pain Management in Veterinary Practice written by Christine M. Egger and published by John Wiley & Sons. This book was released on 2013-12-31 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain Management in Veterinary Practice provides veterinary practitioners with the information needed to recognize and manage pain in a wide range of large, small, and exotic animal species. Encompassing acute, adaptive, and chronic, maladaptive pain, the book provides an up-to-date review of the physiology and pathophysiology of pain. Pain Management in Veterinary Practice offers specific strategies for addressing pain in animals, including local and regional analgesia, continuous rate infusions, and novel methods of analgesic drug delivery. With comprehensive information on the pharmacokinetic and pharmacodynamic characteristics of analgesic drugs, the book goes beyond pharmaceutical options to incorporate scientific information on techniques for complementary treatment, including physical therapy, acupuncture, chiropractic techniques, and nutritional strategies. Pain Management in Veterinary Practice is a valuable resource for developing pain management protocols in the veterinary clinic.

Download or read book Clinical Pain Management Second Edition Acute Pain written by Pamela Macintyre and published by CRC Press. This book was released on 2008-09-26 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute Pain brings coverage of this diverse area together in a single comprehensive clinical reference, from the basic mechanisms underlying the development of acute pain, to the various treatments that can be applied to control it in different clinical settings. Much expanded in this second edition, the volume reflects the huge advances that continue to be made in acute pain management. Part One examines the basic aspects of acute pain and its management, including applied physiology and development neurobiology, the drugs commonly used in therapy, assessment, measurement and history-taking, post-operative pain management and its relationship to outcome, and preventive analgesia. Part Two reviews the techniques used for the management of acute pain. Methods of drug delivery and non-pharmacological treatments including psychological therapies in adults and children and transcutaneous electrical nerve stimulation are considered here. Part Three looks at the many clinical situations in which acute pain can arise, and the methods of treatment that may be suitable in each circumstance, whether the patient is young or old, has pain due to surgery, trauma, medical illness or childbirth, or is undergoing rehabilitation. Issues specific to the management of acute pain in the developing world are also covered here.

Download or read book Practical Management of Pain written by Honorio Benzon and published by Elsevier Health Sciences. This book was released on 2022-02-10 with total page 1520 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 30 years, Practical Management of Pain has offered expert guidance to both clinicians and trainees, covering every aspect of acute and chronic pain medicine for adult and pediatric patients. The fully revised 6th Edition brings you fully up to date with new developments in patient evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. Edited by a team of renowned pain clinicians led by Dr. Honorio Benzon, this authoritative reference is a comprehensive, practical resource for pain diagnosis and treatment using a variety of pharmacologic and physical modalities. Presents a wealth of information in a clearly written, easily accessible manner, enabling you to effectively assess and draw up an optimal treatment plan for patients with acute or chronic pain. Takes a practical, multidisciplinary approach, making key concepts and techniques easier to apply to everyday practice. Shares the knowledge and expertise of global contributors on all facets of pain management, from general principles to specific management techniques. Discusses the latest, best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents such as topical analgesics. Covers recent global developments regarding opioid induced hyperalgesia, neuromodulation and pain management, and identification of specific targets for molecular based pain. Includes current information on the use of cannabinoids in pain management and related regulatory, professional, and legal considerations. Includes the latest guidelines on facet injections and safety of contrast agents. Provides new, evidence-based critical analysis on treatment modality outcomes and the latest information on chronic pain as a result of surgical interventions.

Download or read book Core Curriculum for Pain Management Nursing E Book written by ASPMN and published by Elsevier Health Sciences. This book was released on 2017-08-02 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn how to successfully work with patients in pain with The Core Curriculum for Pain Management Nursing, 3rd Edition. Written by the American Society for Pain Management Nursing (the primary nursing organization in pain management), this easy-to-read text covers the entire scope of pain management in a very user-friendly outline format. This new edition has been thoroughly updated to reflect the latest standards and scope of practice put forth by the ASPMN. Yet, it still retains its strong nursing focus as it explores the nurse’s role as a patient advocate in pain management and how that role changes from a Registered Nurse to a Clinical Nurse Specialist to a Nurse Practitioner. Both pharmacologic and non-pharmacologic methods of pain management are discussed, as is a wide variety of patient subsets beyond the traditional pediatric, adult, and geriatric patient. If you’re looking to pass the ASPMN credentialing exam and work successfully with all types of patients in pain, then this is the perfect text for you! Content written by the ASPMN (American Society for Pain Management Nursing), the primary nursing organization in pain management, ensures the material is authoritative and timely. UNIQUE! Expansive patient coverage addresses not only adults, pediatric and geriatric patients, but also key subsets of patients — such as those who have concomitant addiction, those who have cancer, those who are under sedation for a procedure, and more. Comprehensive coverage discusses important topics — such as the disparities in pain management, gender differences in pain and analgesia, the effect of depression on pain perception and management, the use of research, various theories of pain management, and more — to fully prepare you for your ASPMN credentialing exam and professional practice. UNIQUE! Strong nursing focus thoroughly explores the nurse’s role as a patient advocate in pain management and how that role changes from a Registered Nurse to a Clinical Nurse Specialist to a Nurse Practitioner. Unique outline format makes the text an accessible and easy-to-read reference. NEW! Coverage of both pharmacologic and non-pharmacologic pain interventions has been updated to keep you abreast of the latest methods for both types of pain management. NEW! Thoroughly updated information reflects the latest standards and scope of practice as well as the blueprint for the ASPMN credentialing exam. NEW! Additional information on pain management in bariatric patients highlight important considerations that you need to know when caring for this specific patient population. NEW! Added illustrations and figures throughout the text make difficult concepts easier to understand.

Download or read book Principles and Practice of Stress Management Fourth Edition written by Paul M. Lehrer and published by Guilford Publications. This book was released on 2021-06 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The leading clinical reference and text on stress management has now been significantly revised with 60% new material reflecting key developments in the field. Foremost experts review the "whats," "whys," and "how-tos" of progressive relaxation, biofeedback, meditation, hypnosis, cognitive methods, and other therapies. Chapters describe each method's theoretical foundations, evidence base, procedures, applications, and contraindications. Assessment and implementation are illustrated with extensive case examples. The volume examines the effects of stress on both mind and body, from basic science to practical implications for everyday life and health care. Subject areas/key words: managing, reduction, relaxation, mindfulness, meditation, pain, biofeedback, interventions, anxiety disorders, techniques, psychotherapy, hypnosis, cognitive therapy, breathing retraining, treatments, textbooks, clinical health psychology, behavioral medicine, psychosomatic Audience: Clinical and health psychologists, psychiatrists, clinical social workers, counselors, and nurses; advanced students in these fields"--

Download or read book Natural Immunomodulators Promising Therapy for Disease Management written by Vandana S. Nikam and published by Bentham Science Publishers. This book was released on 2023-05-16 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Immunomodulators: Promising Therapy for Disease Management discusses the use of natural immunomodulators as a promising therapy for managing various diseases. The book begins with an introduction to the immune system and the ways in which it can be modulated. This is followed by a discussion on the various diseases and disorders associated with the immune system, including autoimmune disorders, allergies, and immune deficiency conditions. The natural sources of immunomodulators, including plants, herbs, and other natural substances is also explained along with the importance of standardizing natural immunomodulator drugs, including the methods used to ensure their quality and consistency. The book also delves into the chemistry and analytical techniques used to study immunomodulators, clinical and pre-clinical bioassays. The next couple of chapters focus on the use of natural immunomodulators in cancer, the therapy of cancer and infectious diseases. Drug delivery and the strategy and regulatory perspective for natural immunomodulators. The final 2 chapters round up the contents with information about synthetic immunomodulators and the future perspective for the use of immunomodulators in disease management. Natural Immunomodulators: Promising Therapy for Disease Management is a comprehensive guide to the use of natural immunomodulators as a therapy for various diseases, and is a valuable resource for professionals and students interested in this topic. The book is aimed at health care professionals such as medical doctors, nurses, pharmacists, and life science and nutritionist professionals, as well as students.

Download or read book Assessment and Multimodal Management of Pain written by Maureen Cooney and published by Elsevier Health Sciences. This book was released on 2020-10-31 with total page 865 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn best practices and evidence-based guidelines for assessing and managing pain! Assessment and Multimodal Management of Pain: An Integrative Approach describes how to provide effective management of pain through the use of multiple medications and techniques, including both pharmacologic and non-pharmacologic treatment regimens. A holistic approach provides an in-depth understanding of pain and includes practical assessment tools along with coverage of opioid and non-opioid analgesics, interventional and herbal approaches to pain, and much more. Written by experts Maureen F. Cooney and Ann Quinlan-Colwell, this reference is a complete, step-by-step guide to contemporary pain assessment and management. Evidence-based, practical guidance helps students learn to plan and implement pain management, and aligns with current guidelines and best practices. Comprehensive information on the pharmacologic management of pain includes nonopioid analgesics, opioid analgesics, and co-analgesics, including dose titration, routes of administration, and prevention of side effects. UNIQUE! Multimodal approach for pain management is explored throughout the book, as it affects assessment, the physiologic experience, and the culturally determined expression, acknowledgement, and management of pain. UNIQUE! Holistic, integrative approach includes thorough coverage of pain management with non-pharmacologic methods. Clinical scenarios are cited to illustrate key points. Equivalent analgesic action for common pain medications provides readers with useful guidance relating to medication selection. Pain-rating scales in over 20 languages are included in the appendix for improved patient/clinician communication and accurate pain assessment. UNIQUE! Authors Maureen F. Cooney and Ann Quinlan-Colwell are two of the foremost authorities in multimodal pain assessment and management. Sample forms, guidelines, protocols, and other hands-on tools are included, and may be reproduced for use in the classroom or clinical setting.

Download or read book Features and Management of Acute and Chronic Neuro Covid written by Marco Cascella and published by Springer Nature. This book was released on 2021-11-27 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book delineates that COVID-19 is a multisystem inflammatory disease and how its pathophysiology can predispose patients to an increased risk of neurological problems. Available data suggest the potential neuroinvasive capacity of the SARS-CoV-2 through direct viral damage and indirect entering the CNS by different routes including the vascular system, the olfactory and trigeminal nerves, the cerebrospinal fluid, and the lymphatic system. Furthermore, the pro-inflammatory cytokine storm and oxidative stress can induce microglial activation and damaging the blood-brain barrier, culminating in widespread neuroinflammatory processes. This acute neurotoxicity is clinically expressed as anosmia, ageusia, headache, nausea and vomiting. Other neurologic manifestations such as acute cerebrovascular diseases, encephalitis-based impaired consciousness, and meningitis are also described. The PNS can also be affected and clinical manifestations including Guillain-Barré syndrome, polyneuritis, Miller Fisher Syndrome, and other problems are described. A special issue concerns the neurocognitive dysfunction and altered consciousness manifested as delirium, agitation, and confusion. Non-specific symptoms such as dizziness, and seizures can accompany clinical pictures. Regardless of the admitting diagnosis, a high percentage of patients discharged from ICUs develop disabilities affecting physical, cognitive and psychological activities. The symptoms such as asthenia, memory disturbances, depression, sleep disturbances, anxiety, and Post-traumatic Stress Disorder (PTSD), can configure the so-called Post-intensive Care Syndrome (PICS). Multimodal management during the ICU stay and implementation of follow-up programs on patient discharge can reduce the incidence of this syndrome, improving the quality of life of surviving individuals. In this complex scenario, a careful clinical approach through reliable diagnostic tools, and epidemiological studies aimed at evaluating the dimensions of the problem also in economic terms, is urgently needed. This book represents a valuable aid for all healthcare professionals (intensivists, neurologist and psychiatrists, as well as others) involved in the management of these critically ill patients.