Download or read book Growth Hormone in Adults written by Anders Juul and published by Cambridge University Press. This book was released on 2000-04-27 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised new edition reviews the substantial advances in our understanding of the vital role of growth hormone (GH) in maintaining adult health, and the resulting disorders from GH deficiency. The first edition, published in 1996, provided a pioneering overview of the subject; this new edition provides an even more comprehensive account, fully updated with the latest research, clinical applications, and references. The therapeutic benefits of GH treatment in GH deficiency are thoroughly evaluated, including effects on metabolism, cardiac function, exercise performance, psychosocial aspects, and aging and gender-specific effects. This compilation by the world's leading experts covers clinical investigation, diagnosis and treatment issues, and encompasses new knowledge of the control and action of GH secretion. This volume is the most authoritative, comprehensive, and detailed account available and will be an essential source of reference for all endocrinologists.
Download or read book Gigantism and Acromegaly written by Constantine A. Stratakis and published by Academic Press. This book was released on 2021-06-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim's appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. - Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism - Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics - Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism
Download or read book Growth Hormone Deficiency in Adults written by Jens O. L. Jørgensen and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been known for over 40 years that GH-deficient-children benefit from replacement with the hormone. But GH, essential for longitudinal growth, also plays a role after completion of final height. With the introduction of biosynthetic human GH 20 years ago, the use of GH was no longer restricted to severe growth retardation in hypopituitary children. This book will take the reader behind the myths of GH and into the real world of clinical endocrinology. The contributions stem from recognized clinicians and scientists who have been working in the field for decades. The contents encompass traditional end points of GH therapy such as body composition, bone biology and physical performance. Attention is also devoted to diagnostic aspects and side effects. Additional features range from clinical epidemiology to quality of life, and novel areas such as the impact of traumatic brain injury on pituitary function are also covered. The present volume of Frontiers of Hormone Research is essential reading for health care professionals interested in clinical endocrinology and GH.
Download or read book Human Growth Hormone written by Adair Stuart Mason and published by . This book was released on 1972 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Growth Hormone is a compendium of papers that discusses all aspects of human growth hormone (HGH) relevant in the treatment of dwarfs who are HGH deficient. This book discusses the approach of growth hormone treatment including the preparation of the hormone, its effect and interactions with other hormones, the methods used to detect growth hormone in human plasma, as well as its clinical applications. One author discusses the preparation of human growth hormone, its storage, method of bioassay, and procedures for ampouling HGH for clinical use. A couple of authors review the metabolic a ...
Download or read book The Passion According to G H written by Clarice Lispector and published by New Directions Publishing. This book was released on 2012-06-13 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lispector’s most shocking novel. The Passion According to G.H., Clarice Lispector’s mystical novel of 1964, concerns a well-to-do Rio sculptress, G.H., who enters her maid’s room, sees a cockroach crawling out of the wardrobe, and, panicking, slams the door—crushing the cockroach—and then watches it die. At the end of the novel, at the height of a spiritual crisis, comes the most famous and most genuinely shocking scene in Brazilian literature… Lispector wrote that of all her works this novel was the one that “best corresponded to her demands as a writer.”
Download or read book Growth Hormone Secretagogues written by E. Ghigo and published by Elsevier. This book was released on 1999-09-07 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Growth hormone secretagogues (GHS) administered alone or in combination with growth hormone releasing hexapeptides, are effective probes for the diagnosis of GH deficiency in both children and adults. Current research has developed and tested different GHS compounds that are active by the oral route, and have improved potency and bioavailability, giving rise to exciting therapeutic possibilities. There was an enthusiastic response from experts in this area to the idea of distilling the huge amount of available data into one multi-authored volume. Each contributor has advanced the field of knowledge, and has here emphasized the practical aspects of their work, reviewing the subject in the light of their own experience. Therefore, the theme of the book is a practical one. The volume deals with all aspects of GHS that are relevant to the field, from the chemical structure to the different analogues, to the cloning and expression of the GHS-receptor and the role of these compounds in the physiological control of GH secretion. Also discussed are the most recent advances in relation to the possible role of these compounds in the diagnostic therapeutic settings in different clinical situations, either in children, adults or the elderly. The book meets the requirement of covering most, if not all of the advances in the field. It will enable scientists and clinicians to keep abreast of the rapidly evolving knowledge of the most recent years, and will also prove useful as a review for all interested in this topic.
Download or read book Growth Hormone Therapy in Pediatrics written by Michael B. Ranke and published by Karger Medical and Scientific Publishers. This book was released on 2007-01-01 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: For 20 years, KIGS (Pfizer International Growth Database) has provided an outstanding tool for monitoring the use, efficacy and safety of growth hormone (GH) treatment in children with short stature of varying origin. This volume offers a comprehensive update of the continuing experiences in KIGS and is based on data from more than 50 countries and more than 60,000 patients. International experts analyse in detail the basic auxological characteristics of patients and their response to GH treatment for a broad spectrum of growth disorders. These include idiopathic GH deficiency, organic GH deficiency due to a variety of causes such as congenital malformations and syndromes, genetic disorders or treatment for leukaemia or central nervous system tumours and short stature in children born small for gestational age, specific syndromes and systemic disorders. Each growth disorder is also covered by a review of relevant published data by international experts. KIGS has also established itself as a primary source of information about adverse events during long-term GH treatment in children. The recent analysis of KIGS data has revealed no new adverse drug reactions since the 10-year follow-up. Therefore, treatment with GH seems a low-risk intervention in children and adolescents with various growth disorders. The process of developing disease-specific growth response prediction models has been ongoing in KIGS for many years. The available models are accurate, precise and have a relatively high degree of predictive power, although further predictors of the growth response remain to be identified. The KIGS prediction models can be applied prospectively to new patients, enabling their GH therapy to be better tailored and monitored to achieve optimal growth, safety and cost outcomes. The future of KIGS within the era of evidence-based medicine will continue to depend upon the quality of the data reported. Therefore, the commitment of participating physicians will continue to be a decisive element. The ongoing recognition of the importance of valid safety and efficacy information in the practice of paediatric endocrinology is exemplified by this valuable international collaboration of clinicians and the pharmaceutical community.
Download or read book Who written by Geoff Smart and published by Ballantine Books. This book was released on 2008-09-30 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this instant New York Times Bestseller, Geoff Smart and Randy Street provide a simple, practical, and effective solution to what The Economist calls “the single biggest problem in business today”: unsuccessful hiring. The average hiring mistake costs a company $1.5 million or more a year and countless wasted hours. This statistic becomes even more startling when you consider that the typical hiring success rate of managers is only 50 percent. The silver lining is that “who” problems are easily preventable. Based on more than 1,300 hours of interviews with more than 20 billionaires and 300 CEOs, Who presents Smart and Street’s A Method for Hiring. Refined through the largest research study of its kind ever undertaken, the A Method stresses fundamental elements that anyone can implement–and it has a 90 percent success rate. Whether you’re a member of a board of directors looking for a new CEO, the owner of a small business searching for the right people to make your company grow, or a parent in need of a new babysitter, it’s all about Who. Inside you’ll learn how to • avoid common “voodoo hiring” methods • define the outcomes you seek • generate a flow of A Players to your team–by implementing the #1 tactic used by successful businesspeople • ask the right interview questions to dramatically improve your ability to quickly distinguish an A Player from a B or C candidate • attract the person you want to hire, by emphasizing the points the candidate cares about most In business, you are who you hire. In Who, Geoff Smart and Randy Street offer simple, easy-to-follow steps that will put the right people in place for optimal success.
Download or read book Clinical Neuroendocrinology written by Michael Wilkinson and published by Cambridge University Press. This book was released on 2019-01-03 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.
Download or read book Watchmakers and Clockmakers of the World written by G. H. Baillie and published by Read Books Ltd. This book was released on 2013-04-16 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Watchmakers and Clockmakers of the World” is a comprehensive reference book of the most notable makers of clocks and watches in the world at the time when this book was first published. It is presented as a series of lists, each containing different information pertaining to the industry and the main companies involved in the manufacture of timepieces. Contents Include: “Conventions Abbreviations”, “List of Names with Alternative Spellings”, “List of Watch and Clockmakers”, “List of Initials and Monograms”, “List of Place Names”, “Maps”, etc. Many vintage books such as this are increasingly scarce and expensive. It is with this in mind that we are republishing this volume now in an affordable, modern, high-quality edition complete with a specially-commissioned new introduction on clockmaking.
Download or read book Ramanujan written by Godfrey Harold Hardy and published by American Mathematical Soc.. This book was released on 1999-01-01 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Another excellent book long out of print but much in demand. This book is pulled together by Ramanujan's primary mentor, G. H. Hardy, who was the first to recognize the amazing nature of Ramanujan's ideas. Another exceptional classic from the Chelsea list.
Download or read book Sex Steroid Interactions with Growth Hormone written by Johannes D. Veldhuis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sex-Steroid Interactions with Growth Hormone presents the proceedings of an international symposium held from October 22-25 in Naples, Florida. The proceedings provide new insights and concepts gained by molecular, cellular and neuroendocrine research into mechanistic interactions of the reproductive and somatotrophic axes. Chapters include discussions of the impact of sex steroids on growth hormone secretion in both children and adults; sex steroids, growth hormone releasing factor, and somatostatin; how sex steroids modulate growth hormone action on target issues; and differential effects of growth hormone secretagogues in men and women. This volume is designed for physicians, scientists and other health professionals interested or trained in clinical and basic endocrinology, growth or reproduction.
Download or read book Endoscopic Endonasal Transsphenoidal Surgery written by Enrico de Divitiis and published by Springer Science & Business Media. This book was released on 2003-08-19 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, surgical management provides the definitive treatment of choice for most pituitary adenomas, craniopharyngiomas and meningiomas of the sellar region. The elegant minimally invasive transnasal endoscopic approach to the sella turcica and the anterior skull base has added a new dimension of versatility to pituitary surgery and can be adapted to many lesions in the region. In this multi-author book with numerous color illustrations the main aspects of the endonasal endoscopic approach to the skull base are presented, starting with a clear description of the endoscopic anatomy, the panoramic view afforded by the endoscope and the development of effective instruments and adjuncts. After the diagnostic studies, the strictly surgical features are considered in detail. The standard technique is described and particular aspects are treated, including the new extended approaches to the cavernous sinus, spheno-ethmoid planum and clival regions. The book stresses the importance of teamwork and has been produced by one of the pioneering groups in the field of endoscopic approaches to the pituitary. It is a useful guide primarily for neurosurgeons and sinonasal endoscopic surgeons but also for other specialists involved in the diagnosis and treatment of skull base lesions.
Download or read book Human Associative Memory written by John R. Anderson and published by Psychology Press. This book was released on 2014-02-25 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1973. This book proposes and tests a theory about human memory, about how a person encodes, retains, and retrieves information from memory. The book is especially concerned with memory for sentential materials. We propose a theoretical framework which is adequate for describing comprehension of linguistic materials, for exhibiting the internal representation of propositional materials, for characterizing the interpretative processes which encode this information into memory and make use of it for remembering, for answering questions, recognizing instances of known categories, drawing inferences, and making deductions.
Download or read book The Decameron written by Giovanni Boccaccio and published by BoD - Books on Demand. This book was released on 2023-07-07 with total page 1040 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the time of a devastating pandemic, seven women and three men withdraw to a country estate outside Florence to give themselves a diversion from the death around them. Once there, they decide to spend some time each day telling stories, each of the ten to tell one story each day. They do this for ten days, with a few other days of rest in between, resulting in the 100 stories of the Decameron. The Decameron was written after the Black Plague spread through Italy in 1348. Most of the tales did not originate with Boccaccio; some of them were centuries old already in his time, but Boccaccio imbued them all with his distinctive style. The stories run the gamut from tragedy to comedy, from lewd to inspiring, and sometimes all of those at once. They also provide a detailed picture of daily life in fourteenth-century Italy.
Download or read book Growth Hormone Secretagogues in Clinical Practice written by Barry B. Bercu and published by CRC Press. This book was released on 1998-04-28 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognizing the urgent need for an up-to-date review of new and innovative research on growth hormone (GH) secretagogues, this exclusive work furnishes the state of the art on the mechanisms of action, design, synthesis, evaluation, and clinical applications of GH secretagogues, including orally active and xenobiotic GH-releasing compounds. Beginning with a thorough historical perspective on the discovery and evolution of GH-releasing peptides (GHRPs) as therapeutic agents, Growth Hormone Secretagogues in Clinical Practice analyzes structural requirements for GH secretagogue efficacy demonstrates the use of mathematical models to predict differential values of individual stimuli for GH secretion from the pituitary reports on the development of a simple screening system based on polyclonal antibodies discusses laboratory synthesis of agonistic analogs intended for human and veterinary use proposes applications in managing conditions such as Turner's syndrome, acromegaly, diabetic retinopathy, glomerulosclerosis, tumors, and cancer provides physiological evidence for the effects of GHRP on behavior with a series of trials involving voluntary and forced exercise describes a new diagnostic test for evaluating pituitary function in slowly growing children and aging adults explores the interactions of GH secretagogues with other hormones and endogenous substances from sex steroids to interferons and much more!
Download or read book Hormonal Regulation of Growth written by Herwig Frisch and published by . This book was released on 1989 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
