Download or read book Fungal Physiology and Immunopathogenesis written by Marcio L. Rodrigues and published by Springer Nature. This book was released on 2019-09-03 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers an overview of the various aspects involved in the ability of fungi to damage host cells, and discusses cutting-edge approaches to the study of fungal pathogenesis. The first chapter illustrate the key roles of glycans and pigments, the most abundant surface components in fungal cells, in their interactions with host cells. The connections between cellular physiology and fungal pathogenesis are then discussed in the following chapters. Physiology-related processes affecting pathogenesis include fungal secretion, morphological transitions, and response to light. In turn, the book illustrates mechanisms of damage to host cells using the Histoplasma capsulatum model of infection, and reviews the use of transcriptomic approaches to understand the mechanisms of interaction between fungal cells and host tissues. After a discussion of the immunological mechanisms underlying host susceptibility to fungal infections, the book’s closing contribution reviews the mechanisms of interaction between fungi and other microbes, and the impact of this association on fungal pathogenesis. Given its scope, the book will appeal to scientists in the fields of mycology, microbiology, infectious diseases, biology and medicine.
Download or read book The Fungal Cell Wall written by Jean-Paul Latgé and published by Springer Nature. This book was released on 2020-08-12 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates, that the fungal cell wall is critical for the biology and ecology of all fungi and especially for human fungal pathogens. Readers will learn, that the composition of the fungal cell wall is a unique structure, which cannot be found in the human host. Consequently, the chapters outline, how the immune systems of both animals and humans have evolved to recognize conserved and unique elements of the fungal cell wall. As an application example, the authors also show, that the three-dimensional structures of the cell wall are excellent targets for the development of antifungal agents and chemotherapeutic strategies. With the combination of biological findings and medical outlooks, this volume is a fascinating read for scientists, clinicians and biomedical students.
Download or read book Fungal Nutrition and Physiology written by Michael O. Garraway and published by Wiley-Interscience. This book was released on 1984-06-25 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The motivation for writing this book came the insights gained 10 years of teaching a are-quarter graduate level course in fungal physiology to students in botany, mycology, microbiology, and plant pathology at the ohio state university. during that period many excellent books were published on all facets of fungal physiology; they included monographs, symposium volumes, and long, ong treatises.
Download or read book Systemic Fungal Infections Principles Pathogenesis Practice written by Monica Mahajan and published by Jaypee Brothers Medical Publishers. This book was released on 2019-08-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fungal Pathogenesis in Humans written by Fernando Leal and published by MDPI. This book was released on 2019-05-27 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dear Colleagues, Cancer survival rates and successful organ transplantation in patients continues to increase due to improvements in early diagnosis and treatments. Since immuno-suppressive therapies are frequently used, the mortality rate due to secondary infections has become an ever-increasing problem. Opportunistic fungal infections are probably the deadliest threat to these patients due to their difficult early diagnosis, the limited effect of antifungal drugs and the appearance of resistances. In recent years, a considerable effort has been devoted to investigating the role of many virulence traits in the pathogenic outcome of fungal infections. New virulence factors (hypoxia adaptation, CO2 sensing, pH regulation, micronutrient acquisition, secondary metabolites, immunity regulators, etc.) have been reported and their molecular mechanisms of action are being thoroughly investigated. The recent application of gene-editing technologies such as CRISPr-Cas9, has opened a whole new window to the discovery of new fungal virulence factors. Accurate fungal genotyping, Next Generation Sequencing and RNAseq approaches will undoubtedly provide new clues to interpret the plethora of molecular interactions controlling these complex systems. Unraveling their intimate regulatory details will provide insights for a more target-focused search or a rational design of more specific antifungal agents. This Special Issue is show significant discoveries, proofs of concept of new theories or relevant observations in fungal pathogenesis and its regulation. Dr. Fernando Leal Guest Editor
Download or read book Practical Fungal Physiology written by Peter M. Robinson and published by John Wiley & Sons. This book was released on 1978 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Physiology of Fungi written by Vincent W. Cochrane and published by . This book was released on 1958 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although study of the physiology of the fungi has not kept pace with that of, for example, bacterial metabolism, it has in recebts decades had much the same development. It seems fair to say that there have been two disparate types of study. Research on some problems-reproduction, parasitism, development-has been, with significant but not very numerous exceptions, descriptive. At the other extreme, it has been possible to develop basic biochemical knowledge on the implicit assumption that the microbial cell is a small bag of enzymes which only require to be extracted and enumerated.
Download or read book Immunity to Human Fungal Pathogens Mechanisms of Host Recognition Protection Pathology and Fungal Interference written by Steven P. Templeton and published by Frontiers Media SA. This book was released on 2019-01-24 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi are found in virtually every environment, and comprise a significant portion of the normal microflora of healthy individuals. Some species of fungi are aeroallergen sources capable of inducing sensitization and causing exacerbation of asthma and respiratory allergy. Others are transmissible between hosts and may cause no symptoms in healthy individuals. However, immune suppressed individuals may develop invasive disease marked by tissue invasion with a potential for widespread dissemination. Existing therapies for patients consist of antifungal drugs, yet these require prolonged administration with the possibility of adverse side effects, and may be rendered ineffective by the emergence of antifungal-resistant strains. It is therefore of interest to increase our understanding of host-pathogen interactions in order to facilitate the development of new therapies for individuals suffering from fungal infection and disease. These early interactions are shaped by an array of constituent and secreted factors that stimulate or inhibit host immune responses toward protective or detrimental immunity. Likewise, an array of preformed factors and tissue-resident cells provide early protection from fungal infection and provide extracellular signals that result in localized recruitment of inflammatory cells and determine the character of subsequent adaptive antifungal immunity. This Research Topic explores the host and fungal pathways that program innate and adaptive immunity and the immune cells, molecules, and regulatory pathways that comprise protective or detrimental responses to fungal exposure or infection. Over 200 authors contributed reviews, opinions, or original research focusing on antifungal immunity in humans and in experimental models. We believe that the results of these efforts provide a benchmark for further advances and improved antifungal therapies.
Download or read book Biology of the Fungal Cell written by Richard J. Howard and published by Springer Science & Business Media. This book was released on 2007-06-30 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: What makes the fungal cell unique among eukaryotes and what features are shared? This volume addresses some of the most prominent and fascinating facets of questions as they pertain to the growth and development of both yeast and hyphal forms of fungi, beginning with subcellular components – then cell organization, polarity, growth, differentiation and beyond – to the cell biology of spores, biomechanics of invasive growth, plant pathogenesis, mycorrhizal symbiosis and colonial networks. Throughout, structural, molecular and ecological aspects are integrated to form a contemporary look at the biology of the fungal cell.
Download or read book Fungal Immunology written by Paul L. Fidel and published by Springer. This book was released on 2014-09-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of all known immune mechanisms for medically important fungal pathogens from the organ perspectives of the human body. This authoritative guide is organized by organ system, as one particular fungus can have several different effects.
Download or read book Plant Pathogenesis written by Harry Wheeler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Advanced Series in Agricultural Sciences is designed to fill a long-felt need for advanced educational and technological books in the agricultural sciences. These texts, intended primarily for students of agriculture, should also provide up-to-date technical background reading for the many agricultural workers in extension services, educational systems, or international bodies. The editors of Advanced Series in Agricultural Sciences will select key subjects relating to the agricultural environment, agricultural physics and chemistry, soil science, plant sciences, animal sciences, food technology, and agricultural engineering for a critical and synthetic appraisal. An initial theoretical presentation will be used by authors of individual volumes in the series to develop a technical approach~including examples and practical solutions~ to each subject. In addressing the advanced undergraduate and early graduate student of agriculture, selected authors will present the latest information, leavened with the lessons learned from their own experience, on precise and well-defined topics. Such books that widen the horizons of the student of agriculture can serve, too, as useful reference sources for the young specialist in the early years of his career. Many specialists who are involved in teaching agricultural science are isolated from universities and research institutions. This series will bring them up-to-date scientific information, thus keeping them in touch with progress. The basic objective of Advanced Series in Agricultural Sciences is to effect a structural integration of the theoretic and technical approaches to agriculture.
Download or read book Pathogenesis of Dimorphic Fungal Infections written by Angel Gonzalez and published by Frontiers Media SA. This book was released on 2022-01-06 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Physiological Plant Pathology written by R. Heitefuß and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 909 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant pathology embraces all aspects of biological and scientific activity which are concerned with understanding the complex phenomena of diseases in plants. Physiological plant pathology represents those specialities within plant pathology which focus on the physiological and biochemical activities of pathogens and on the response of host plant tissues. Today there is an increasing recognition on the part of the scientific agri cultural community that only through a deeper and more fundamental under standing of all the interacting components of the agricultural biota can we expect to improve our capabilities of feeding an expanding world population. It is in this context that physiological plant pathology has assumed new significance within the broader field of plant pathology. No longer are studies on the biochemistry and physiology of pathogens and pathogenesis merely isolated academic exercises; rather, a substantial coherent body of knowledge is accumulating upon which our understanding of the process of disease developmen t and host resistance is being founded. It is from these foundations of knowledge that ultimately new insights into the control of plant diseases may be expected to grow. It seems appropriate, therefore, that at regular intervals those involved in the various subspecialities encompassing the broadest aspects of physiological plant pathology reassess the contributions within the particular specialities in the light of new knowledge and technologies for the purpose of articulating new and productive directions for the future.
Download or read book Fungal Infections and Immune Responses written by Juneann W. Murphy and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical scientists widely acknowledge that individuals' immune respon siveness is important in resistance to infections by microorganisms, including fungi. Because of the devastating acquired immunodeficiency syndrome (AIDS) epidemic, caused by the human immunodeficiency retrovirus, it is now accepted that suppressed immune responses, especially cellular immu nity, are important contributors to increased individual susceptibility to opportunistic infections-including infections caused by fungi which were at one time thought to be very lowly or nonpathogenic. Within the last few years, there has been an almost explosive increase in interest and studies concerning the nature and mechanisms of the immune response to fungal infections. Many immunologists who are not well versed in mycology have begun to study the nature and mechanisms of antifungal immunity using a wide variety of newer as well as more conventional immunologic technologies, both in vivo and in vitro. Up to the 1980s, however, there was little interest among basic immunologists concerning fungal immunity. This situation has changed dramatically in the past half decade, mainly because of AIDS.
Download or read book Essentials of Clinical Mycology written by Carol A. Kauffman and published by Springer Science & Business Media. This book was released on 2011-01-12 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Mycology offers a comprehensive review of this discipline. Organized by types of fungi, this volume covers microbiologic, epidemiologic and demographic aspects of fungal infections as well as diagnostic, clinical, therapeutic, and preventive approaches. Special patient populations are also detailed.
Download or read book Fungal Cell Wall and Immune Response written by J.P. Latge and published by Springer. This book was released on 1991-06-28 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent findings on the role of the cell wall of pathogenetic fungi in the pathogenic processes of both vertebrates and invertebrates are presented. The fungal cell wall not only gives shape to the fungus, but it is a dynamic structure allowing fungal growth and survival of fungi in both friendly and adverse environments. It acts as a living sieve controlling the entry of nutrients and the secretion of metabolic products. In terms of fungal pathogenesis, the fungal wall may be responsible for eliciting the defense response of their respective invertebrate or vertebrate hosts or conversely it may provide protection against the host defense system during the pathogenic process.
Download or read book Fungal Pathogenesis written by Richard Calderone and published by CRC Press. This book was released on 2001-10-12 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stresses molecular and biochemical studies of opportunistic and frank fungal pathogens! This book gives a comprehensive overview of human pathogenic fungi that offers a current and concise survey of virulence factors, host responses and recognition, treatment and diagnosis of infections, invasive enzymes, intracellular survival, morphogenesis, adaptation, and properties of major fungal pathogens that contribute to disease. Focuses on human fungal infections, including candidiasis, pneumocystosis, aspergillosis, and cryptococcosis. With over 3700 references to accommodate continuing study, Fungal Pathogenesis covers natural and acquired immunity, vaccine development, and immune reconstitution outlines rapid identification of major mycoses utilizing antigen capture and molecular assays details signaling and phenotypic switching discusses the value of genomics in validation highlights state-of-the-art molecular methodologies to study disease-causing organisms describes available and potential antifungal drug targets and drug development considers predicting the consequences of drug resistance on patient management presents topical observations on strain typing and variation and more! Containing research into the virulence, immunity, diagnosis, and therapy of most common fungal infections, Fungal Pathogenesis is an unparalleled reference for microbiologists, virologists, pathologists and phytopathologists, infectious disease specialists, molecular and cell biologists, biochemists, immunologists, medical mycologists, biotechnologists, and geneticists, and an exceptional text for upper-level undergraduate, graduate, and medical school students in these disciplines.
