Download or read book Functionalized Carbon Nanotubes as a Multimodal Drug Delivery System for Target Cancer Therapy written by Elena Heister and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Emerging Applications of Carbon Nanotubes in Drug and Gene Delivery written by Prashant Kesharwani and published by Woodhead Publishing. This book was released on 2022-11-05 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging Applications of Carbon Nanotubes in Drug and Gene Delivery brings together principles behind the formation, characterization and development of carbon nanotubes (CNTs) with recent advances in drug and gene delivery applications. The book begins with an introduction to the unique properties of CNTs, as well as the various synthesis, purification and functionalization methods available. Later chapters cover drug and gene delivery using CNTs for therapeutic applications, comparing advantages and disadvantages of each. The book then goes on to discuss toxicity and safety challenges in using CNTs in biomedicine, with a forward-look at regulatory requirements and clinical translations. This book offers a detailed reference for materials scientists, biomedical engineers, pharmaceutical scientists and geneticists interested in CNTs and nanomedicine. Provides focused coverage of nanotubes for use in drug and gene delivery applications, offering much-needed detail amongst broader nanomedicine texts Details the properties, characterization, synthesis, functionalization and applications of CNTs in drug and gene delivery Discusses toxicity, safety and regulatory aspects of CNTs, with a look towards the clinical translation of CNTs

Download or read book Fullerens Graphenes and Nanotubes written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2018-05-28 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fullerens, Graphenes and Nanotubes: A Pharmaceutical Approach shows how carbon nanomaterials are used in the pharmaceutical industry. While there are various books on the carbonaceous nanomaterials available on the market, none approach the subject from a pharmaceutical point-of-view. In this context, the book covers different applications of carbonaceous nanomaterials. Chapters examine different types of carbon nanomaterials and explore how they are used in such areas as cancer treatments, pulse sensing and prosthetics. Readers will find this book to be a valuable reference resource for those working in the areas of carbon materials, nanomaterials and pharmaceutical science. Explains how the unique properties of carbon-based nanomaterials allow them to be used to create effective drug delivery systems Covers how carbon-based nanomaterials should be prepared for use in pharmaceutical applications Discusses the relative toxicity of a range of carbon-based nanomaterials Considers the safety of their use in different types of drugs

Download or read book Carbon Nanotubes for Targeted Drug Delivery written by Md Saquib Hasnain and published by Springer Nature. This book was released on 2019-11-08 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed introduction to carbon nanotubes (CNTs) for targeted drug delivery. After a brief overview of the classification, preparation, and characterization of carbon nanotubes, it focuses on their use in targeted drug delivery. It presents CNTs for brain targeting, ocular targeting, cancer targeting, and lymphatic targeting, as well as antibody therapy. The book also includes chapters on carbon nanotubes for controlled drug delivery, transdermal drug delivery, solubility enhancement, vaccine delivery, gene delivery, and as quantum dots. Last but not least, it addresses the absorption and transportation of CNTs, toxicity and regulatory considerations, as well as clinical trials and the market status of CNTs. The book offers a comprehensive, self-contained reference guide, with all topics covered concisely and with the help of figures, tables and flowcharts.

Download or read book Carbon Nanotubes for Biomedical Applications written by Rüdiger Klingeler and published by Springer Science & Business Media. This book was released on 2011-02-09 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the potential of multi-functional carbon nanotubes for biomedical applications. It combines contributions from chemistry, physics, biology, engineering, and medicine. The complete overview of the state-of-the-art addresses different synthesis and biofunctionalisation routes and shows the structural and magnetic properties of nanotubes relevant to biomedical applications. Particular emphasis is put on the interaction of carbon nanotubes with biological environments, i.e. toxicity, biocompatibility, cellular uptake, intracellular distribution, interaction with the immune system and environmental impact. The insertion of NMR-active substances allows diagnostic usage as markers and sensors, e.g. for imaging and contactless local temperature sensing. The potential of nanotubes for therapeutic applications is highlighted by studies on chemotherapeutic drug filling and release, targeting and magnetic hyperthermia studies for anti-cancer treatment at the cellular level.

Download or read book Carbon Nanotubes for Biomedical Applications and Healthcare written by Chin Hua Chia and published by CRC Press. This book was released on 2024-03-12 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advancements and research in nanotechnology, biotechnology, materials engineering the applications of nanomaterial are evolving. Carbon nanotubes (CNT) and CNT-based systems possess unique chemical, physical, and biological properties that make them good candidates in biomedical applications, but they also have some inherent properties that cause great concern about their biosafety. This volume explores the practical applications of carbon nanotubes in biomedical science and human health. It discusses the synthesis, properties, modification, and recent progress of carbon nanotubes and their applications for biosensing, cancer treatment, antibacterial therapy, tissue engineering, targeted drug delivery, and toxicity. It relays the potential and promise of carbon-based nanomaterials for host of applications while also looking at the challenges in synthesis, characterization, and applications of nanomaterials and how to overcome them.

Download or read book Antibody functionalized Carbon Nanotubes Towards a Targeted Anticancer Therapy written by Enrica Venturelli and published by . This book was released on 2011 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, carbon nanotubes (CNTs) have emerged as new and promising materials for applications in different research fields such as nanotechnology and materials science. Recent studies on the ability of CNTs to form supramolecular complexes with nucleic acids or proteins triggered their applications in the biomedical domain, for example as drug delivery system. In this thesis, I focused my interest on the design and synthesis of antibody-CNT conjugates for targeted cancer therapy. The nanotubes are used as delivery system whereas the antibody is the targeting moiety for cancer cells. Nowadays antibodies represent a promising anticancer therapy, however they have not been utilized against intracellular targets because of their low aptitude to traverse the plasma membrane. On the contrary, CNTs have shown the ability to easily cross cell membrane via two mechanisms (endocytosis or passive diffusion). Results confirmed the possibility to covalently functionalize carbon nanotubes either with a targeting antibody or a therapeutic immunoglobulin. Once bound onto the surface of CNTs (sidewall or tips), surface plasmon resonance results displayed the conservation of the ability of the antibody to recognize the antigen. Important aspects related to the biomedical applications of these constructs are the evaluation of their potential toxicity and biodistribution profiles. Results indicated that the conjugates are biocompatible and they distribute mainly in liver, spleen and lungs. This work shows great promise for the use of functionalized carbon nanotubes as novel delivery system for drugs or bioactive molecules.

Download or read book Multifunctional Nanocomposites for Targeted Drug Delivery in Cancer Therapy written by Awesh K. Yadav and published by Elsevier. This book was released on 2023-12-01 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multifunctional Nanocomposites for Targeted Drug Delivery in Cancer Therapy explores the design, synthesis, and application of different multifunctional nanocomposites drug delivery system for cancer treatment. It encompasses initial chapters discussing introductory information about cancer, followed by chapters focusing on the detailed information about various novel drug delivery systems for treatment of several organ site cancers such as prostate, skin, breast, lung, liver, pancreas, stomach, colon, blood, mouth and throat. It is a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical research who need to understand more about novel nanotechnologies applied to cancer treatment. Discusses a wide range of promising approaches for the diagnosis and treatment of cancer using the latest advancement in cutting-edge nanomedical technologies Presents chapters dedicated to each cancer type and the best nanocomposite therapies used, making the content easily discoverable by readers Written by world-renowned experts and researchers in the areas of nanomedicine, drug delivery and cancer research to explore thoroughly the topic with diverse perspectives

Download or read book Functionalized Carbon Nanotubes for Biomedical Applications written by Jeenat Aslam and published by John Wiley & Sons. This book was released on 2023-03-28 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: FUNCTIONALIZED CARBON NANOTUBES FOR BIOMEDICAL APPLICATIONS The book highlights established research and technology on current and emerging trends and biomedical applications of functionalized carbon nanotubes by providing academic researchers and scientists in industry, as well as high-tech start-ups, with knowledge of the modern practices that will revolutionize using functionalized carbon nanotubes. Nanotechnology suggests fascinating opportunities for a variety of applications in biomedical fields, including bioimaging and targeted delivery of biomacromolecules into cells. Numerous strategies have been recommended to functionalize carbon nanotubes with raised solubility for efficient use in biomedical applications. Functionalized carbon nanotubes have unique arrangements and extravagant mechanical, thermal, magnetic, optical, electrical, surface, and chemical properties, and the combination of these features gives them widespread biomedical applications. Functionalized carbon nanotubes are relatively flexible and interact with the cell membranes and penetrate different biological tissues owing to a “snaking” effect, therefore both the pharmacological and toxicological profiles of functionalized carbon nanotubes have gathered much attention in recent times. This book covers a broad range of topics relating to carbon nanotubes, from synthesis and functionalization to applications in advanced biomedical devices and systems. As they possess unique and attractive physical, chemical, optical, and even magnetic properties for various applications, considerable effort has been made to employ functionalized carbon nanotubes as new materials for the development of novel biomedical tools, such as diagnostic sensors, imaging agents, and drug/gene delivery systems for both diagnostics and clinical treatment. Audience The book is intended for a very broad audience of researchers and scientists working in the fields of nanomaterials, nanomedicine, bioinspired nanomaterials, nanotechnology, and biomedical application of nanomaterials.

Download or read book Carbon Nanotubes in Drug and Gene Delivery written by Mahdi Karimi and published by Morgan & Claypool Publishers. This book was released on 2017-10-31 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent important discoveries and developments in nanotechnology have had a remarkable and ever-increasing impact on many industries, especially materials science, pharmaceuticals, and biotechnology. Nanocarriers have been investigated for a wide variety of different medical applications. Some examples of these nanocarriers include polymersomes, liposomes, micelles and carbon-based nanomaterials. Within this book, the authors describe different features of carbon nanotubes (CNTs), survey the properties of both the multi-walled and single-walled varieties, and cover their applications in drug and gene delivery. In addition, the book explains the structure and properties of CNTs prepared by different method, and discussed their isolation and purification. The future of CNTs in the field of biomedical science will depend on minimizing their adverse effects by careful study of their structure and properties.

Download or read book Nanomaterial Based Drug Delivery Carriers for Cancer Therapy written by Tao Feng and published by Springer. This book was released on 2016-12-09 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brief summarizes different types of organic and inorganic nanomaterials for drug delivery in cancer therapy. It highlights that precisely designed nanomaterials will be the next-generation therapeutic agents for cancer treatment.

Download or read book Carbon Nanotubes written by Michael J. O’Connell and published by CRC Press. This book was released on 2018-10-03 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since their discovery more than a decade ago, carbon nanotubes (CNTs) have held scientists and engineers in captive fascination, seated on the verge of enormous breakthroughs in areas such as medicine, electronics, and materials science, to name but a few. Taking a broad look at CNTs and the tools used to study them, Carbon Nanotubes: Properties and Applications comprises the efforts of leading nanotube researchers led by Michael O’Connell, protégé of the late father of nanotechnology, Richard Smalley. Each chapter is a self-contained treatise on various aspects of CNT synthesis, characterization, modification, and applications. The book opens with a general introduction to the basic characteristics and the history of CNTs, followed by discussions on synthesis methods and the growth of “peapod” structures. Coverage then moves to electronic properties and band structures of single-wall nanotubes (SWNTs), magnetic properties, Raman spectroscopy of electronic and chemical behavior, and electromechanical properties and applications in NEMS (nanoelectromechanical systems). Turning to applications, the final sections of the book explore mechanical properties of SWNTs spun into fibers, sidewall functionalization in composites, and using SWNTs as tips for scanning probe microscopes. Taking a fresh look at this burgeoning field, Carbon Nanotubes: Properties and Applications points the way toward making CNTs commercially viable.

Download or read book Carbon Based Nanocarriers for Drug Delivery written by Mihir Kumar Purkait and published by CRC Press. This book was released on 2023-10-12 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbon-Based Nanocarriers for Drug Delivery enlists the latitudes and advancements in the synthesis processes, functionalization, and applications of carbon-based nanomaterials (CBNs) in targeted drug delivery systems (DDSs). It covers the applicability and suitability of CBNs as nanocarriers for efficient drug delivery application via elucidating the recent advancements in CBNs, their functionalized and innovative derivatives, and the relevant case studies. The book explores the necessity, efficacy, toxicological aspects, and challenges for the application of CBN in targeted DDSs. Some of the features of this book are provided as follows: Provides elaborative description on significance and adaptability of carbon-based nanomaterial in targeted drug delivery for wide ranges of therapeutics Delivers a full-spectrum discussion on drug delivery through carbon-based nanocarriers Explores each carbon-based nanocarrier fundamentally for its drug and gene-delivery-related applications Describes critical discussion on various toxicological effects over the utilization of these nanocarriers Embraces existing as well as novel technologies/methodologies related to the synthesis and functionalization of CBNs, including graphene, graphene oxide, carbon quantum dots, carbon nanotube, fullerene, and smart carbon-based nanocarriers This book is aimed at researchers and graduate students in materials and pharmaceutical engineering, including drug delivery systems.

Download or read book Targeted Drug Delivery Using Carbon Nanotubes for Cancer Therapeutics written by Ashwinkumar A. Bhirde and published by . This book was released on 2009 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Carbon Nanotubes written by Ann Rose Abraham and published by CRC Press. This book was released on 2022-10-06 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book discusses a selection of advanced topics on carbon nanotubes—their extraordinary properties, structure, design, fabrication, development, engineering, functionalization, carbon nanotube enabled nanocomposites, characterization, and, moreover, their utility in many applications. The volume highlights the amazing potential of advanced CNT composites in automotive, aeronautics, spacecrafts, transistors replacing Si electronics, energy, purification, hydrogen storage, tissue regeneration, electrochemical supercapacitors, sensing, biomedical applications, agriculture, energy, and technical applications. The book specifically discusses the applications of carbon nanotubes for a greener environment, as well as applications for biomedical uses, in drug delivery, and in display technology. It also explores the uses of CNTs in the energy and aerospace industries, such as for solar energy conversion, as a lubricant additive for enhancing energy efficiency, and more. Other chapters explore the potential of carbon nanotubes in hydrogen storage and carbon nanotube electronics.

Download or read book Carbon Nanotubes for Biomedical Applications written by Rüdiger Klingeler and published by Springer. This book was released on 2011-07-23 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the potential of multi-functional carbon nanotubes for biomedical applications. It combines contributions from chemistry, physics, biology, engineering, and medicine. The complete overview of the state-of-the-art addresses different synthesis and biofunctionalisation routes and shows the structural and magnetic properties of nanotubes relevant to biomedical applications. Particular emphasis is put on the interaction of carbon nanotubes with biological environments, i.e. toxicity, biocompatibility, cellular uptake, intracellular distribution, interaction with the immune system and environmental impact. The insertion of NMR-active substances allows diagnostic usage as markers and sensors, e.g. for imaging and contactless local temperature sensing. The potential of nanotubes for therapeutic applications is highlighted by studies on chemotherapeutic drug filling and release, targeting and magnetic hyperthermia studies for anti-cancer treatment at the cellular level.

Download or read book Carbon Nanotube Based Targeted Drug Delivery Systems for Breast Cancer and Other Drug Delivery Applications written by Wei Shao and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Breast cancer is the most commonly diagnosed cancer in women and the second leading cause of death among all cancers. Surgical removal of breast tumour tissues is the primary treatment for breast cancer. However, this does not rule out relapse at local or distant sites, so, chemotherapy is widely used as an adjuvant therapy. Although effective, chemotherapy drugs often cause severe side effects due to their non-specificity to cancer cells. Nanotechnology for drug delivery is an emerging field focused on targeting drugs to the desirable sites, such as tumour tissues, while minimizing the unwanted side effects of chemotherapy drugs on other tissues. Discovery of a new type of nanomaterial opens more opportunities for drug delivery. The carbon nanotube (CNT) is a novel type of synthetic material that has shown great potential for targeted delivery of anti-cancer agents. The initial hurdle for biomedical applications of CNT has been its hydrophobicity. Proper surface modification of CNT, or CNT functionalization, so as to prepare well-dispersed and biocompatible CNT in biologically compatible solutions, is a primary step for its biomedical application. In this thesis, noncovalent functionalization of CNT using various polymers is first explored to make well-dispersed CNT. By identifying the problems of the existing CNT-based drug delivery systems, three novel schemes for CNT-based, targeted drug delivery systems are designed and developed for delivery of a potent breast cancer chemotherapy drug paclitaxel (PTX). The three CNT-PTX delivery systems are characterized and evaluated for their toxicity, drug-loading capacity, cell penetration and cancer cell growth inhibition in vitro. Of the three schemes, the CNT-drug carrier developed through a lipid-drug approach is the best delivery system in terms of drug loading capacity, targeted drug delivery features and potential multifunctional drug delivery. Hence, the CNT-lipid-drug delivery system has been selected for further evaluation for its in vivo tumour growth inhibition, safety and toxicity using a breast cancer xenograft mice model. The CNT-lipid-drug approach has shown good results in a breast cancer animal model. Overall, this thesis explores a new type of nanomaterial as a drug carrier to overcome major limitations of chemotherapy drugs. As a newly discovered nanomaterial, research on CNT as a drug carrier is still in its infancy. Each of these schemes offers a new route of drug loading on CNT, which contributes to our present knowledge on construction of CNT-based drug delivery systems." --