Download or read book Function of the Kinesin like Motor Protein CHO1 in Cytokinesis of Mammalian Cells written by Jurgita Matuliene and published by . This book was released on 2003 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Kinesins and Cancer written by Frank Kozielski, FSB and published by Springer. This book was released on 2015-03-02 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This interdisciplinary volume collates research work on kinesins and cancer. Authors attempt to validate members of the kinesin superfamily as potential targets for drug development in cancer chemotherapy. The work begins by highlighting the importance of kinesins, summarising current knowledge and how they are shown to be crucial for mitosis. Chapters go on to explore how this family of proteins are emerging as a novel target for chemotherapeutic intervention and drug development. Readers will learn how kinesins travel along microtubules to fulfill their many roles in intracellular transport or cell division. Several compounds that inhibit two mitotic kinesins (called Eg5 and CENP-E) have entered Phase I and II clinical trials and are explored in these chapters. Additional mitotic kinesins are currently being validated as drug targets, raising the possibility that the repertoire of kinesin-based drug targets may expand in the future. The book is suitable as a reference standard for the field of kinesins and cancer. It will interest those in academia and pharmaceutical companies, and anyone with an interest in the medical relevance of these proteins, which cutting edge methodologies are now enabling us to understand in astonishing detail.
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2004 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dynamics of Cell Division written by Sharyn A. Endow and published by OUP Oxford. This book was released on 1998-10-01 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the structural aspects of cell division - concentrating on both nuclear division (meiosis and mitosis) and cytoplasmic division (cytokinesis). Written as a companion volume to the earlier book in the series - Cell Cycle Control, this book provides an up-to-date account of developments in this exciting area of cell biology.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2005 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Polyploidization and Cancer written by Randy Y.C. Poon and published by Springer Science & Business Media. This book was released on 2011-01-11 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overview subjects relating to polyploidization and cancer.
Download or read book Molecular Motors written by Manfred Schliwa and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest knowledge on molecular motors is vital for the understanding of a wide range of biological and medical topics: cell motility, organelle movement, virus transport, developmental asymmetry, myopathies, and sensory defects are all related to the function or malfunction of these minute molecular machines. Since there is a vast amount of information on motor mechanisms and potential biomedical and nanobiotechnological applications, this handbook fulfills the need for a collection of current research results on the functionality, regulation, and interactions of cytoskeletal, DNA, and rotary motors. Here, leading experts present a concise insight, ranging from atomic structure, biochemistry, and biophysics to cell biology, developmental biology and pathology. Basic principles and applications make this book a valuable reference tool for researchers, professionals, and clinicians alike - all set to become a "classic" in the years to come.
Download or read book The Journal of Cell Biology written by and published by . This book was released on 2008 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-
Download or read book Journal of Cell Science written by and published by . This book was released on 2004 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book International Review of Cytology written by Kwang W. Jeon and published by Elsevier. This book was released on 2004-12-07 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume address biosynthesis and alternate targeting of the lysosomal cysteine protesase cathepsin L; microtubule-associated proteins and their essential roles during mitosis; molecular and functional analysis of the dictyostelium centrosome; polytene chromosomes; and insect basic leucine zipper proteins and their role in cyclic AMP dependent regulation of gene expression.
Download or read book Cytoskeleton and Human Disease written by Maria Kavallaris and published by Springer Science & Business Media. This book was released on 2012-04-23 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cytoskeleton is comprised of a variety of specialized proteins, and is a dynamic structure that is involved in the majority of key cellular events. There is increasing interest in the role of the cytoskeleton in human disease. This volume brings together human disease states where cytoskeletal disruptions are driving disease. Our emerging understanding of the molecular and cellular events that drive cytoskeletal mediated diseases including cancer, heart disease, myopathies and skin disorders, are also helping shape targeted therapeutic approaches to treating these diseases.
Download or read book The Cytoskeletal Basis of Plant Growth and Form written by Clive W. Lloyd and published by . This book was released on 1991 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Factors affecting the shape of plant cells have been studied since the last century and are increasingly described in molecular terms. At the cellular level it is now known that shape is controlled by interactions between the cytoskeleton and the cell wall. This book concentrates on the nature of this relationship and its place in the developmental program. Chapters are relatively short and summarize progress over the last decade brought about by advances in cellular and molecular techniques. The contents are organized from molecular, through cellular, to developmental aspects which are grouped according to major themes such as "Molecules of the Cytoskeleton", "Directional Cell Expansion" and "The Cytoskeleton in Development". Each section opens with an editorial overview. The comprehensive nature of the book helps make it an indispensable reference for researchers and advanced students in plant cell and molecular biology. Key Features * Updates Lloyd's previous book on plant cytoskeletons * Consists of short, up-to-date contributions, divided into sections which are linked by special pieces written by the editor * The sections cover: * Cytoskeleton molecules * The cell wall * Cell expansion * Cell division * The role of the cytoskeleton in plant development
Download or read book Cytokinesis in Animal Cells written by R. Rappaport and published by Cambridge University Press. This book was released on 1996-10-28 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book traces the history of the major ideas and gives an account of our current knowledge of cytokinesis.
Download or read book The Functional Studies of a Novel Golgi Specific Spectrin Protein written by Jun Fan and published by . This book was released on 2003 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drosophila Oogenesis written by Diana P. Bratu and published by Humana. This book was released on 2015-09-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides current up-to-date protocols for preparing the ovary for various imaging techniques, genetic protocols for generating mutant clones, mosaic analysis and assessing cell death. Chapters address methods for performing genome wide gene expression analysis and bioinformatics for studies of RNA-protein interactions. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Drosophila Oogenesis: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Download or read book Frontiers in Protein Structure Function and Dynamics written by Dev Bukhsh Singh and published by Springer Nature. This book was released on 2020-07-02 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances. Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecular motors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins. Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction.
Download or read book Cytokinesis written by and published by Academic Press. This book was released on 2017-01-02 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytokinesis, the latest volume in the Methods in Cell Biology series, looks at the latest advances in cytokinesis. Edited by leaders in the field, this volume presents proven, state-of-art techniques, along with relevant historical background and theory, to aid researchers in efficient design and effective implementation of experimental methodologies. Covers sections on cytokinesis and emerging studies Presents chapters written by experts in the field Includes cutting-edge materials that supplement study
