Download or read book Frontiers in Immunobiology and Immunosuppression written by Hans W. Sollinger and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Frontiers in Immunobiology and Immunosuppression written by and published by . This book was released on 1996 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Proceedings of a Symposium on Frontiers and Immunobiology and Immunosuppression written by Symposium on Frontiers in Immunobiology and Immunosuppression. 1995, Wien and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Frontiers in Immunobiology and Immunosuppression written by and published by . This book was released on 1996 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Frontiers in Immunobiology and Immunosuppression written by Hans W. Sollinger and published by . This book was released on 1996 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Frontiers in Immunobiology and Immunosuppression written by Hans W. Sollinger and published by . This book was released on 1996 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Proceedings of a Symposium on Frontiers in Immunobiology and Immunosuppression Vienna Austria October 3 1995 written by Hans W. Sollinger and published by . This book was released on 1996 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Proceedings of a Symposium on Frontiers in Immunobiology and Immunosuppression written by Hans W. Sollinger and published by . This book was released on 1996 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Immune Rebalancing written by Diana Boraschi and published by Academic Press. This book was released on 2016-01-25 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Rebalancing: The Future of Immunosuppression summarizes the most promising perspectives of immunopharmacology, in particular in the area of immunosuppression by considering molecular pathways, personalized medicine, microbiome and nanomedicine. Modulation of immune responses for therapeutic purposes is a particularly relevant area, given the central role of anomalous immunity in diseases. These diseases vary from the most typically immune-related syndromes (autoimmune diseases, allergy and asthma, immunodeficiencies) to those in which altered immunity and inflammation define the pathological outcomes (chronic infections, tumours, chronic inflammatory and degenerative diseases, metabolic disorders, etc. - Visits immunosuppression from a modern point of view of signalling mechanisms at the light of the current knowledge of signalling mechanisms and regulatory networks allows the reader to formulate new ideas and concepts on how to use immunosuppression the therapeutic purposes - Encourages researchers to engage into exploring the field of pharmacological modulation of immune responses in depth, and with the new knowledge and tools available, designs more effective therapeutic strategies to autoimmune and inflammatory diseases, cancer, degenerative diseases and infections - Examines the link between molecular pathways associated to immune-suppression and the new immunopharmacology approaches - Provides information on the new strategies for drug development in this field - Considers the role of microbes in the development of the mammalian immune system and immune responses, which will widen the reader's strategy for addressing therapeutic immune modulations

Download or read book Venoms and Toxins At the Crossroads of Basic Applied and Clinical Immunology written by Manuela Berto Pucca and published by Frontiers Media SA. This book was released on 2021-08-26 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Immunomodulation written by H. Hugh Fudenberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: On May 14-16, 1982, a group of scientists met in Viareggio, Italy to present ideas, and exchange relevant data on current approaches on immunomodulators. We felt that the embodiment of the substance of that international symposium into this volume will be beneficial in keeping both clinicians and basic scientists abreast of the latest exciting developments in this rapidly accelerating field. We hope that the publication of this series of papers by an international panel of experts will enhance the nature of future inves t igat ive stud ies with such ent it ies . Under the rubric of immunology, it is obvious that such a term as "immunomodulation" could be construed as being all encompassing. However, it is intriguing that the immune modulators touched on in these sessions can be subcategorized into about five broad groups. Almost all substances, excepting those entities that are immuno logically inert, will have some modulating effects on immunity. From the coarse adjustment of antibody feedback inhibition upon cellular limnunity to the subtle finesse envisioned in Jerne's idiotypic network and s'lppressor T cells, immunomodulators attempt to either magnify or diminish those responses that are normally elicited by antigen. The broad groups - thymic hormones, D.L.E., Interferon, drugs, and the use of bacterial products appear to be at the forefront of much of the pioneering work on immunomodulation.

Download or read book The Role of TNF TNFR2 Signal in Immunosuppressive Cells and its Therapeutic Implications written by Xin Chen and published by Frontiers Media SA. This book was released on 2020-01-20 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: CD4+FoxP3+ regulatory T cells (Tregs) play an indispensable role in the maintenance of immune homeostasis and prevention of autoimmune diseases, and represent a major cellular mechanism of tumor immune evasion. Targeting of Tregs has great potential in the treatment of some major human diseases, including autoimmunity, transplant rejection, GvHD, and cancer, and are critical controllers of immunity to infectious pathogens. It is expected they will also be central to the control of allergic and inflammatory diseases. Understanding the biological pathways crucial for the regulation of Treg activity is a prerequisite for harnessing the immense therapeutic potential of Tregs. TNF is generally believed to be a master pro-inflammatory cytokine, and anti-TNF therapy has become a mainstay treatment for some autoimmune diseases. However, experimental evidence indicates that TNF preferentially activates Tregs, resulting in the expansive proliferation, phenotypic stability, and enhanced suppressive capacity of these immune suppressors. This effect of TNF is mediated by TNFR2, which is preferentially expressed by human and mouse Tregs. Furthermore, expression of TNFR2 is able to identify the most suppressive subset of Tregs. Although counterintuitive and contradictory to earlier reports, these findings have been supported by increasing experimental evidence from both human and mouse studies. These recent studies revealing the Treg-promoting effect of TNF not only leads to the redefinition of the immunological biology of this pleiotropic cytokine, they are also helpful in designing novel therapies in the treatment of cancer, autoimmune diseases, and GvHD, as well as enhancing current vaccines and immunomodulators. In this article collection, current knowledge on the cellular and molecular aspects of the Treg-stimulatory effect of the TNF-TNFR2 pathway will be discussed. An insight of the physiological and pathological roles of such effects of TNF in an inflammatory reaction and immune response will be provided. The seemingly contradictory Treg-promoting effect of TNF and immunosuppressive effect of anti-TNF therapy will be analyzed. Recent efforts to translate such discoveries into therapeutic benefits will be introduced. The novel strategies in the treatment of cancer and GvHD, by down- or up-regulation of Treg activity through targeting TNFR2, will be highlighted. In addition to Tregs, TNFR2 has also been found to play a key role in the accumulation and immunosuppressive function of myeloid-derived suppressive cells (MDSCs) and Mesenchymal stem cells (MSCs). Therefore, the current understanding of the role of TNF-TNFR2 signal in other type of immunosuppressive cells, as well as its clinical and therapeutic implications, have also been considered.

Download or read book Systems Biology in Cancer Immunotherapy written by Mahbuba Rahman and published by Bentham Science Publishers. This book was released on 2016-06-07 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decades, systems biology approaches have been applied in different areas of life science research including oncology. Researchers now understand the hallmarks of cancer cells such as abnormal cell growth, inflammation, dysregulated metabolic pathways and drug resistance properties at a molecular level. Systems biology approaches have enabled researchers to investigate cancer immunology by identifying cancer related biomarkers on immune cells, and to study the effect of different therapies in tissue cultures and mouse models. Systems Biology in Cancer Immunotherapy explains the scope of systems biology in understanding the immune response to neoplasms. The book introduces readers to the concepts crucial to cancer immunology before delving into the applied systems biology topics such as the metabolic pathways in cancer cells, the biomolecular roles of signal transduction molecules and their respective biochemical pathways ad cancer immunotherapy. A brief conclusion at the end also provides some information from a clinical and commercial perspective on cancer immunotherapy. This volume is intended as an introductory reference for life science and medical students, researchers and academics interested in the application of systems biology to the immune system in oncology research and chemotherapy practice.

Download or read book The Immunology of Sepsis Understanding Host Susceptibility Pathogenesis of Disease and Avenues for Future Treatment written by Luregn J. Schlapbach and published by Frontiers Media SA. This book was released on 2020-08-19 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.

Download or read book Frontiers in Cancer Immunology Systems Biology in Cancer Immunotherapy written by Mahbuba Rahman and published by Frontiers in Cancer Immunology. This book was released on 2016-06-07 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decades, systems biology approaches have been applied in different areas of life science research including oncology. Researchers now understand the hallmarks of cancer cells such as abnormal cell growth, inflammation, dysregulated metabolic pathways and drug resistance properties at a molecular level. Systems biology approaches have enabled researchers to investigate cancer immunology by identifying cancer related biomarkers on immune cells, and to study the effect of different therapies in tissue cultures and mouse models. Systems Biology in Cancer Immunotherapy explains the scope of systems biology in understanding the immune response to neoplasms. The book introduces readers to the concepts crucial to cancer immunology before delving into the applied systems biology topics such as the metabolic pathways in cancer cells, the biomolecular roles of signal transduction molecules and immunotherapy. A brief conclusion at the end also provides some information from a clinical and commercial perspective on cancer immunotherapy. This volume is intended as an introductory reference for life science and medical students, researchers and academics interested in the application of systems biology to the immune system in cancer patients.

Download or read book Modulation of Human Immune Parameters by Anticancer Therapies written by Ulrich Sack and published by Frontiers Media SA. This book was released on 2021-01-18 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nutrition and Immune Function written by Philip C. Calder and published by CABI. This book was released on 2002-01-01 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a review of the roles of specific nutrients in maintaining the immune response and host protection against infection. It also considers the influence of various factors, such as exercise and ageing, on the interaction between nutrition and immune function.