Download or read book Fred Sanger Double Nobel Laureate written by George G. Brownlee and published by Cambridge University Press. This book was released on 2020-04-02 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considered 'the father of genomics', Fred Sanger (1918–2013) paved the way for the modern revolution in our understanding of biology. His pioneering methods for sequencing proteins, RNA and, eventually, DNA earned him two Nobel Prizes. He remains one of only four scientists (and the only British scientist) ever to have achieved that distinction. In this, the first full biography of Fred Sanger to be published, Brownlee traces Sanger's life from his birth in rural Gloucestershire to his retirement in 1983 from the Medical Research Council's Laboratory of Molecular Biology in Cambridge. Along the way, he highlights the remarkable extent of Sanger's scientific achievements and provides a real portrait of the modest man behind them. Including an extensive transcript of a rare interview of Sanger by the author, this biography also considers the wider legacy of Sanger's work, including his impact on the Human Genome Project and beyond.

Download or read book Frederick Sanger written by Joe S. Jeffers and published by Springer. This book was released on 2017-03-14 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this Brief, Joe Jeffers uncovers the life and works of two-time Nobel Laureate Frederick Sanger. Following Sanger’s early life to retirement, Jeffers describes how this celebrated British biochemist became the first person to determine the amino acid sequence of a protein for which he was awarded the Nobel Prize in 1958. Highlighting Sanger’s remarkable career, Jeffers describes Sanger’s later change in research direction to investigate deoxyribonucleic acids (DNA), work for which Sanger also received the Nobel Prize jointly with Paul Berg and Walter Gilbert in 1980. Joe Jeffers conducted twelve interviews with Sanger over the period of 1999-2009 and he has also spoken to more than 40 of Sanger’s colleagues and family members. This brief provides a rigorous yet concise view of Sanger on a personal and scientific level and is suitable for biochemists, historians or the interested layperson.

Download or read book Selected Papers of Frederick Sanger written by Frederick Sanger and published by World Scientific. This book was released on 1996 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important volume is mainly concerned with the development of methods for ?sequencing? ? that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger's first paper resulted in finding a second amino acid. In his final paper in 1982 he describes the determination of a DNA sequence of 48,502 nucleotides. The papers describe the steady improvements in techniques, and exciting biological results revealed by the sequences.

Download or read book Diabetes The Biography written by Robert Tattersall and published by OUP Oxford. This book was released on 2009-10-08 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes is a disease with a fascinating history and one that has been growing dramatically with urbanization. According to the World Health Authority, it now affects 4.6% of adults over 20, reaching 30% in the over 35s in some populations. It is one of the most serious and widespread diseases today. But the general perception of diabetes is quite different. At the beginning of the 20th century, diabetes sufferers mostly tended to be middle-aged and overweight, and could live tolerably well with the disease for a couple of decades, but when it occasionally struck younger people, it could be fatal within a few months. The development of insulin in the early 1920s dramatically changed things for these younger patients. But that story of the success of modern medicine has tended to dominate public perception, so that diabetes is regarded as a relatively minor illness. Sadly, that is far from the case, and diabetes can produce complications affecting many different organs. Robert Tattersall, a leading authority on diabetes, describes the story of the disease from the ancient writings of Galen and Avicenna to the recognition of sugar in the urine of diabetics in the 18th century, the identification of pancreatic diabetes in 1889, the discovery of insulin in the early 20th century, the ensuing optimism, and the subsequent despair as the complexity of this now chronic illness among its increasing number of young patients became apparent. Yet new drugs are being developed, as well as new approaches to management that give hope for the future. Diabetes affects many of us directly or indirectly through friends and relatives. This book gives an authoritative and engaging account of the long history and changing perceptions of a disease that now dominates the concerns of health professionals in the developed world. Diabetes: the biography is part of the Oxford series, Biographies of Diseases, edited by William and Helen Bynum. In each individual volume an expert historian or clinician tells the story of a particular disease or condition throughout history - not only in terms of growing medical understanding of its nature and cure, but also shifting social and cultural attitudes, and changes in the meaning of the name of the disease itself.

Download or read book Lives And Times Of Great Pioneers In Chemistry Lavoisier To Sanger written by C N R Rao and published by World Scientific. This book was released on 2015-11-18 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical science has made major advances in the last few decades and has gradually transformed in to a highly multidisciplinary subject that is exciting academically and at the same time beneficial to human kind. In this context, we owe much to the foundations laid by great pioneers of chemistry who contributed new knowledge and created new directions. This book presents the lives and times of 21 great chemists starting from Lavoisier (18th century) and ending with Sanger. Then, there are stories of the great Faraday (19th century) and of the 20th century geniuses G N Lewis and Linus Pauling. The material in the book is presented in the form of stories describing important aspects of the lives of these great personalities, besides highlighting their contributions to chemistry. It is hoped that the book will provide enjoyable reading and also inspiration to those who wish to understand the secret of the creativity of these great chemists.

Download or read book The Discovery of Insulin written by Michael Bliss and published by University of Toronto Press. This book was released on 2017-06-22 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.

Download or read book Nobel Prize Laureates written by and published by . This book was released on 1980 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book About Abortion written by Carol Sanger and published by Belknap Press. This book was released on 2017-03-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most private decisions a woman can make, abortion is also one of the most contentious topics in American civic life. Protested at rallies and politicized in party platforms, terminating pregnancy is often characterized as a selfish decision by women who put their own interests above those of the fetus. This background of stigma and hostility has stifled women’s willingness to talk about abortion, which in turn distorts public and political discussion. To pry open the silence surrounding this public issue, Sanger distinguishes between abortion privacy, a form of nondisclosure based on a woman’s desire to control personal information, and abortion secrecy, a woman’s defense against the many harms of disclosure. Laws regulating abortion patients and providers treat abortion not as an acceptable medical decision—let alone a right—but as something disreputable, immoral, and chosen by mistake. Exploiting the emotional power of fetal imagery, laws require women to undergo ultrasound, a practice welcomed in wanted pregnancies but commandeered for use against women with unwanted pregnancies. Sanger takes these prejudicial views of women’s abortion decisions into the twenty-first century by uncovering new connections between abortion law and American culture and politics. New medical technologies, women’s increasing willingness to talk online and off, and the prospect of tighter judicial reins on state legislatures are shaking up the practice of abortion. As talk becomes more transparent and acceptable, women’s decisions about whether or not to become mothers will be treated more like those of other adults making significant personal choices.

Download or read book The End of Racism written by Dinesh D'Souza and published by Simon and Schuster. This book was released on 1996-09-30 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first conprehensive inquiry into the history, nature and ultimate meaning of racism.

Download or read book Poets Philosophers Lovers written by Frederick Luis Aldama and published by University of Pittsburgh Press. This book was released on 2020-10-27 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a foreword by Ilan Stavans This collection of essays, by fifteen scholars across diverse fields, explores forty years of writing by Giannina Braschi, one of the most revolutionary Latinx authors of her generation. Since the 1980s, Braschi’s linguistic and structural ingenuities, radical thinking, and poetic hilarity have spanned the genres of theatre, poetry, fiction, essay, musical, manifesto, political philosophy, and spoken word. Her best-known titles are El imperio de los sueños, Yo-Yo Boing!, and United States of Banana. She writes in Spanish, Spanglish, and English and embraces timely and enduring subjects: love, liberty, creativity, environment, economy, censorship, borders, immigration, debt, incarceration, colonialization, terrorism, and revolution. Her work has been widely adapted into theater, photography, film, lithography, painting, sculpture, comics, and music. The essays in this volume explore the marvelous ways that Braschi’s texts shake upside down our ideas of ourselves and enrich our understanding of how powerful narratives can wake us to our higher expectations.

Download or read book The Eighth Day of Creation written by Horace Freeland Judson and published by . This book was released on 2004-01-01 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Wilson and Walker s Principles and Techniques of Biochemistry and Molecular Biology written by Andreas Hofmann and published by Cambridge University Press. This book was released on 2018-04-19 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing this best-selling textbook right up to date, the new edition uniquely integrates the theories and methods that drive the fields of biology, biotechnology and medicine, comprehensively covering both the techniques students will encounter in lab classes and those that underpin current key advances and discoveries. The contents have been updated to include both traditional and cutting-edge techniques most commonly used in current life science research. Emphasis is placed on understanding the theory behind the techniques, as well as analysis of the resulting data. New chapters cover proteomics, genomics, metabolomics, bioinformatics, as well as data analysis and visualisation. Using accessible language to describe concepts and methods, and with a wealth of new in-text worked examples to challenge students' understanding, this textbook provides an essential guide to the key techniques used in current bioscience research.

Download or read book Chemical Embryology 2 written by Joseph Needham and published by Palala Press. This book was released on 2018-03 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Download or read book An Unfinished Agenda written by K Anji Reddy and published by Penguin UK. This book was released on 2015-01-15 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: From his birth in a village in Andhra to founding and running Dr. Reddy’s Laboratories, now one of India’s largest pharmaceutical enterprises, Dr K. Anji Reddy’s journey makes for an inspiring story. That story is told rivetingly in his own words in his memoir, An Unfinished Agenda. Dr Anji Reddy became an entrepreneur at a time when India was woefully short of technology to manufacture many basic medicines. Then, in barely three decades, the Indian pharmaceutical industry had grown to the point that India not only became self-sufficient in medicine, but also a supplier of affordable generic medicines to the world. Dr Anji Reddy provides a ringside view of this remarkable transformation, with fascinating anecdotes about those who made it happen. The history of modern medicine is a gripping story of triumphs and failures. An Unfinished Agenda takes the reader on a whirlwind tour of the science of medicine over the last hundred years and reminds us of the stark challenges that remain.

Download or read book A Choice of Anglo Saxon Verse written by Richard Hamer and published by Faber & Faber. This book was released on 2016-06-30 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Choice of Anglo-Saxon Verse contains the Old English texts of all the major short poems, such as 'The Battle of Maldon', 'The Dream of the Rood', 'The Wanderer' and 'The Seafarer', as well as a generous representation of the many important fragments, riddles and gnomic verses that survive from the seventh to the twelfth centuries, with facing-page verse translations. These poems are the well-spring of the English poetic tradition, and this anthology provides a unique window into the mind and culture of the Anglo-Saxons. The volume is an essential companion to Faber's edition of Beowulf, translated by Seamus Heaney.

Download or read book What is Life written by Paul Nurse and published by . This book was released on 2021-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nature s Robots written by Charles Tanford and published by OUP Oxford. This book was released on 2003-11-27 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins are amazingly versatile molecules. They make the chemical reactions happen that form the basis for life, they transmit signals in the body, they identify and kill foreign invaders, they form the engines that make us move, and they record visual images. All of this is now common knowledge, but it was not so a hundred years ago. Nature's Robots is an authoritative history of protein science, from the origins of protein research in the nineteenth century, when the chemical constitution of 'protein' was first studied and heatedly debated and when there was as yet no glimmer of the functional potential of substances in the 'protein' category, to the determination of the first structures of individual proteins at atomic resolution - when positions of individual atoms were first specified exactly and bonding between neighbouring atoms precisely defined. Tanford and Reynolds, who themselves made major contributions to the golden age of protein science, have written a remarkably vivid account of this history. It is a fascinating story, involving heroes from the past, working mostly alone or in small groups, usually with little support from formal research groups. It is also a story that embraces a number of historically important scientific controversies. Written in clear and accessible prose, Nature's Robots will appeal to general readers with an interest in popular science, in addition to professional scientists and historians of science.