Download or read book Forward Time Population Genetics Simulations written by Bo Peng and published by John Wiley & Sons. This book was released on 2012-01-25 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only book available in the area of forward-time population genetics simulations—applicable to both biomedical and evolutionary studies The rapid increase of the power of personal computers has led to the use of serious forward-time simulation programs in genetic studies. Forward-Time Population Genetics Simulations presents both new and commonly used methods, and introduces simuPOP, a powerful and flexible new program that can be used to simulate arbitrary evolutionary processes with unique features like customized chromosome types, arbitrary nonrandom mating schemes, virtual subpopulations, information fields, and Python operators. The book begins with an overview of important concepts and models, then goes on to show how simuPOP can simulate a number of standard population genetics models—with the goal of demonstrating the impact of genetic factors such as mutation, selection, and recombination on standard Wright-Fisher models. The rest of the book is devoted to applications of forward-time simulations in various research topics. Forward-Time Population Genetics Simulations includes: An overview of currently available forward-time simulation methods, their advantages, and shortcomings An overview and evaluation of currently available software A simuPOP tutorial Applications in population genetics Applications in genetic epidemiology, statistical genetics, and mapping complex human diseases The only book of its kind in the field today, Forward-Time Population Genetics Simulations will appeal to researchers and students of population and statistical genetics.
Download or read book Statistical Population Genomics written by Julien Y Dutheil and published by . This book was released on 2020-10-08 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Statistical Population Genomics aims to promote and ensure successful applications of population genomic methods to an increasing number of model systems and biological questions. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Download or read book Genetic Dissection of Complex Traits written by D.C. Rao and published by Academic Press. This book was released on 2008-04-23 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Five sections on the latest advances in complex traits Methods for testing with ethical, legal, and social implications Hot topics include discussions on systems biology approach to drug discovery; using comparative genomics for detecting human disease genes; computationally intensive challenges, and more
Download or read book Population Genetics written by Matthew B. Hamilton and published by John Wiley & Sons. This book was released on 2011-09-23 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.
Download or read book Mathematical Population Genetics 1 written by Warren J. Ewens and published by Springer Science & Business Media. This book was released on 2004-01-09 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.
Download or read book Ecology written by Michael Begon and published by John Wiley & Sons. This book was released on 2020-11-17 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: A definitive guide to the depth and breadth of the ecological sciences, revised and updated The revised and updated fifth edition of Ecology: From Individuals to Ecosystems – now in full colour – offers students and practitioners a review of the ecological sciences. The previous editions of this book earned the authors the prestigious ‘Exceptional Life-time Achievement Award’ of the British Ecological Society – the aim for the fifth edition is not only to maintain standards but indeed to enhance its coverage of Ecology. In the first edition, 34 years ago, it seemed acceptable for ecologists to hold a comfortable, objective, not to say aloof position, from which the ecological communities around us were simply material for which we sought a scientific understanding. Now, we must accept the immediacy of the many environmental problems that threaten us and the responsibility of ecologists to play their full part in addressing these problems. This fifth edition addresses this challenge, with several chapters devoted entirely to applied topics, and examples of how ecological principles have been applied to problems facing us highlighted throughout the remaining nineteen chapters. Nonetheless, the authors remain wedded to the belief that environmental action can only ever be as sound as the ecological principles on which it is based. Hence, while trying harder than ever to help improve preparedness for addressing the environmental problems of the years ahead, the book remains, in its essence, an exposition of the science of ecology. This new edition incorporates the results from more than a thousand recent studies into a fully up-to-date text. Written for students of ecology, researchers and practitioners, the fifth edition of Ecology: From Individuals to Ecosystems is anessential reference to all aspects of ecology and addresses environmental problems of the future.
Download or read book Evolution and Selection of Quantitative Traits written by Bruce Walsh and published by Oxford University Press. This book was released on 2018-06-21 with total page 1504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important. Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 (1998) dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection (ranging from the use of genomic and historical data through to ecological field data) and examining its consequences.
Download or read book Population Genetics written by John H. Gillespie and published by JHU Press. This book was released on 2004-08-06 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description
Download or read book Coalescent Theory written by John Wakely and published by Roberts. This book was released on 2016-04-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides the foundation for molecular population genetics and genomics. It shows the conceptual framework for studies of DNA sequence variation within species, and is the source of essential tools for making inferences about mutation, recombination, population structure and natural selection from DNA sequence data.
Download or read book Polyploid Population Genetics and Evolution From Theory to Practice written by Hans D. Daetwyler and published by Frontiers Media SA. This book was released on 2020-01-28 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Evolutionary Theory written by Sean H. Rice and published by Sinauer Associates Incorporated. This book was released on 2004 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolutionary Theory is for graduate students, researchers, and advanced undergraduates who want an understanding of the mathematical and biological reasoning that underlies evolutionary theory. The book covers all of the major theoretical approaches used to study the mechanics of evolution, including classical one- and two-locus models, diffusion theory, coalescent theory, quantitative genetics, and game theory. There are also chapters on theoretical approaches to the evolution of development and on multilevel selection theory. Each subject is illustrated by focusing on those results that have the greatest power to influence the way that we think about how evolution works. These major results are developed in detail, with many accompanying illustrations, showing exactly how they are derived and how the mathematics relates to the biological insights that they yield. In this way, the reader learns something of the actual machinery of different branches of theory while gaining a deeper understanding of the evolutionary process. Roughly half of the book focuses on gene-based models, the other half being concerned with general phenotype-based theory. Throughout, emphasis is placed on the fundamental relationships between the different branches of theory, illustrating how all of these branches are united by a few basic, universal, principles. The only mathematical background assumed is basic calculus. More advanced mathematical methods are explained, with the help of an extensive appendix, when they are needed.
Download or read book Conceptual Breakthroughs in Evolutionary Ecology written by Laurence Mueller and published by Academic Press. This book was released on 2019-11-19 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although biologists recognize evolutionary ecology by name, many only have a limited understanding of its conceptual roots and historical development. Conceptual Breakthroughs in Evolutionary Ecology fills that knowledge gap in a thought-provoking and readable format. Written by a world-renowned evolutionary ecologist, this book embodies a unique blend of expertise in combining theory and experiment, population genetics and ecology. Following an easily-accessible structure, this book encapsulates and chronologizes the history behind evolutionary ecology. It also focuses on the integration of age-structure and density-dependent selection into an understanding of life-history evolution. - Covers over 60 seminal breakthroughs and paradigm shifts in the field of evolutionary biology and ecology - Modular format permits ready access to each described subject - Historical overview of a field whose concepts are central to all of biology and relevant to a broad audience of biologists, science historians, and philosophers of science
Download or read book The Neolithic Transition and the Genetics of Populations in Europe written by Albert J. Ammerman and published by Princeton University Press. This book was released on 2014-07-14 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the shift from hunting and gathering to agriculture as a way of life and the implications of this neolithic transition for the genetic structure of European populations. Originally published in 1984. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Download or read book Mathematical Population Genetics 1 written by Warren J. Ewens and published by Springer Science & Business Media. This book was released on 2012-10-01 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.
Download or read book Epistasis written by Ka-Chun Wong and published by . This book was released on 2021 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Practical Computing for Biologists written by Steven H.D. Haddock and published by Sinauer. This book was released on 2011-04-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Computing for Biologists shows you how to use many freely available computing tools to work more powerfully and effectively. The book was born out of the authors' own experience in developing tools for their research and helping other biologists with their computational problems. Many of the techniques are relevant to molecular bioinformatics but the scope of the book is much broader, covering topics and techniques that are applicable to a range of scientific endeavours. Twenty-two chapters organized into six parts address the following topics (and more; see Contents): • Searching with regular expressions • The Unix command line • Python programming and debugging • Creating and editing graphics • Databases • Performing analyses on remote servers • Working with electronics While the main narrative focuses on Mac OS X, most of the concepts and examples apply to any operating system. Where there are differences for Windows and Linux users, parallel instructions are provided in the margin and in an appendix. The book is designed to be used as a self-guided resource for researchers, a companion book in a course, or as a primary textbook. Practical Computing for Biologists will free you from the most frustrating and time-consuming aspects of data processing so you can focus on the pleasures of scientific inquiry.
Download or read book Studies in Population Genetics written by M. Carmen Fusté and published by BoD – Books on Demand. This book was released on 2012-08-22 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with central concepts in population genetics, describing the main evolutionary processes that influence the allele frequency distribution and change. The different chapters discuss topics such as population size and structure, migration, inbreeding and interbreeding, mechanisms of extinction and speciation, along with different data techniques and molecular methods used for detecting DNA sequence variation in the study of genetic polymorphisms. Part of the book includes statistical and computational methods commonly used to process population genetics data, which constitute an essential tool for understanding the concepts discussed. The book will be a useful reference for graduate students and researchers working on population genetics, and other related areas including microbiology, genetics, molecular biology, ecology, anthropology and others.
