Download or read book Feline Infectious Peritonitis and Coronavirus written by Diane D. Addie, Ph.d. and published by CreateSpace. This book was released on 2013-04 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Feline infectious peritonitis (FIP) is a major killer of pedigree/purebred kittens and cats from rescue shelters in the 21st century. FIP is one of the most enigmatic, and difficult to diagnose, feline diseases. FIP is caused by feline coronavirus (FCoV), but most cats infected with FCoV do not develop FIP. The key messages of this book are: 1. The most important way to prevent FIP is by preventing infection with feline coronavirus.2. Have any new kitten or cat tested for FCoV antibodies before bringing him or her into your home, if you already have cats.3. Most cats infected with FCoV eliminate the virus after a few months, and remain perfectly healthy.4. Cats become infected with FCoV by contact with cat litter (or cat litter dust particles) contaminated with virus laden faeces from an infected cat.5. Most cats suspected of having FIP actually have some other, often treatable, condition.

Download or read book Clinical Small Animal Internal Medicine written by David Bruyette and published by John Wiley & Sons. This book was released on 2020-03-25 with total page 4856 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Small Animal Internal Medicine is a comprehensive, practical reference designed to meet the needs of veterinary practitioners and students alike. Covering all aspects of small animal internal medicine, this innovative guide provides clinically relevant material, plus podcasts and continual updates online. Concise, identically-formatted chapters allow readers to quickly find the most essential information for clinical veterinary practice. Contributions from academic and clinical experts cover general medicine subjects, including patient evaluation and management, critical care medicine, preventative care, and diagnostic and therapeutic considerations. Topics relevant to daily clinical practice are examined in detail, ranging from endocrine, cardiovascular, respiratory, and infectious disease to oncology, dermatology, metabolic orthopedic disease, gastroenterology, and hepatology. A companion website features podcasts and updated information. An important addition to the library of any practice, this clinically-oriented text: Presents complete, practical information on small animal internal medicine Provides the background physiology required to understand normal versus abnormal in real-world clinical settings Includes general medicine topics not covered in other internal medicine books Focuses on information that is directly applicable to daily practice Features podcasts and continual updates on a companion website Carefully tailored for the needs of small animal practitioners and veterinary students, Clinical Small Animal Internal Medicine is an invaluable, reader-friendly reference on internal medicine of the dog and cat.

Download or read book Infectious Diseases of the Dog and Cat E Book written by Jane E. Sykes and published by Elsevier Health Sciences. This book was released on 2013-09-27 with total page 1376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive reference for the diagnosis, treatment, and prevention of small animal infections, Infectious Diseases of the Dog and Cat, 4th Edition delivers current, comprehensive information essential to the management of infectious diseases caused by viruses, rickettsiae, chlamydiae, mycoplasmas, bacteria, fungi, algae, protozoa, and unknown agents. Each section guides you through diagnostic testing for specific microorganisms, from sample collection to laboratory submission to interpretation of results, then details appropriate treatment measures and pharmacologic considerations for the various related infections. Full-color illustrations and hundreds of tables provide quick, convenient access to diagnostic and therapeutic guidelines, and thoroughly updated drug information helps you confidently administer appropriate dosages for the most effective treatment and prevention. The most comprehensive infectious disease coverage available helps you confidently address clinical problems related to infectious diseases in dogs and cats, and includes: Immunization strategies and environmental control of infections Immunodeficiency disorders Prevention of infection in multi-pet and shelter settings Immunocompromised people and their pets Vibrant full-color illustrations clarify disease features and modes of disease transmission for enhanced diagnostic accuracy and disease prevention. Convenient tables deliver therapeutic recommendations and drug dosages at a glance. Complete antimicrobial drug formulary provides fast, easy access to indications, recommended dosages, and pharmacologic considerations essential for all relevant pharmaceuticals. State-of-the-art diagnostic testing procedures help you ensure accurate diagnoses for all clinically relevant pathogens. Content reflects the expert insight and vast clinical experience of a panel of trusted authorities on small animal infectious diseases. Easy-to-use companion website provides convenient online access to additional images, tables, boxes, appendices, and references linked directly to original PubMed abstracts. Expanded coverage of zoonoses, zoonotic potential, and precautions helps you effectively monitor and treat zoonotic infections. Fully updated drug formulary reflects the most current pharmacokinetics, indications, contraindications, handling and administration guidelines, and dosage recommendations available. Updated content throughout the text details current diagnostic testing regimens and therapeutic and preventive considerations for all pathogens you're likely to encounter in the clinical setting. Special focus on disease incidence and susceptibility in traveling animals helps you alert animal owners to potential risks associated with pet travel.

Download or read book The Coronaviridae written by Stuart G. Siddell and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronaviruses were recognized as a group of enveloped, RNA viruses in 1968 and accepted by the International Committee on the Taxonomy of Viruses as a separate family, the Coronaviridae, in 1975. By 1978, it had become evident that the coronavirus genomic RNA was infectious (i. e. , positive strand), and by 1983, at least the framework of the coronavirus replication strategy had been per ceived. Subsequently, with the application of recombinant DNA techniques, there have been remarkable advances in our understanding of the molecular biology of coronaviruses, and a mass of structural data concerning coronavirus genomes, mRNAs, and pro teins now exists. More recently, attention has been focused on the role of essential and accessory gene products in the coronavirus replication cyde and a molecular analysis of the structure-function relation ships of coronavirus proteins. Nevertheless, there are still large gaps in our knowledge, for instance, in areas such as the genesis of coronavirus subgenomic mRNAs or the function of the coronavirus RNA-dependent RNA polymerase. The diseases caused by coronaviruses have been known for much longer than the agents themselves. Possibly the first coronavirus-related disease to be recorded was feline infectious peritonitis, as early as 1912. The diseases associ ated with infectious bronchitis virus, transmissible gastroenteritis virus, and murine hepatitis virus were all well known before 1950.

Download or read book Coronaviruses written by M. Lai and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronaviruses have emerged during the past ten years from being a group of viruses causing a variety of minor veterinary and human diseases to a major virus group of both clinical significance and molecular biological interest. Against this background, two international coronavirus symposia were held in 1980 and 1983. In recent years, the pace of coronavirus research has been quickened even more by infusion of recombinant DNA technology and establishment of various animal model systems to study the pathogenesis and immunology of coronavirus infections. We therefore organized the Third International Coronavirus Symposium held at Asilomar, California in September 1986, which was attended by more than 120 participants representing a cross section of both academia and industry. This symposium provided an exciting and stimulating forum for assessing the progress made since the last triennial symposium in Netherlands and to suggest the directions for future efforts. This volume collects the scientific papers presented in this symposium. Three loosely defined areas, Molecular biology, Virus-Cell Interaction and Viral Pathogenesis, are separated. These papers very nicely summarize the current status of coronavirus research. They contain a large amount of sequence data, including the complete sequence of a 27 Kb coronavirus genome, a novel mechanism of mRNA synthesis that is unique to coronviruses, and many exciting aspects of coronavirus pathogenesis and immunology. Reflecting the growing interest in the preparation of vaccines, several papers also address the issues related to coronavirus vaccines, which is an area new to this symposium. Dr.

Download or read book Small Animal Pediatrics E Book written by Michael E. Peterson and published by Elsevier Health Sciences. This book was released on 2010-06-10 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical reference for the general veterinary clinician, Small Animal Pediatrics: The First 12 Months of Life compiles into a single location the latest information in the rapidly developing field of canine and feline pediatrics. Editors Michael Peterson, DVM, MS, and Michelle Kutzler, DVM, PhD, DACT are joined by more than 40 expert contributors in providing coverage from prenatal care to one year of age. For ease of use, the text is divided into four sections. A General Considerations section opens the book by covering prenatal care of the bitch and queen, birth, normal physical examinations, growth, husbandry, nutrition, care of orphans, neonatal mortality, behavior, emergency and critical care, and immunology. The second section, Common Infectious Diseases, covers bacterial, viral, fungal, rickettsial, and parasitic infections. The third section describes diagnostic and therapeutic approaches to the young patient including radiology, ultrasound, aesthetic and surgical considerations, pain management, pharmacology, and clinical pathology. Finally, the fourth section covers a variety of organ systems with discussions on normal development, congenital conditions, and acquired diseases. The text also includes information that is usually difficult to find, including a pediatric formulary, care of orphan puppies, clinical pathology values, prenatal care, and normal growth and development guidelines. This book will be a significant asset to any veterinary library! Offers a practical, clinically oriented resource for the unique diagnostic and treatment challenges posed by pediatric and juvenile animal patients. Includes comprehensive coverage of all special problems encountered in pet management from birth through the first 12 months of life. Provides clear, step-by-step guidelines for important clinical procedures and techniques for the most vulnerable of small animal patients. Covers procedures such as intraosseous catheterization and fluid therapy, venipuncture, and tube feeding. Includes guidelines for designing and implementing a successful pediatric wellness program tailored to your own practice. Discusses infectious diseases in young animals, zoonotic potential, and human public health concerns. Provides key new information on puppy and kitten behavioral development including guidance for prevention and intervention for problem behaviors, the leading cause of pet euthanasia. Includes guidelines for kennel and cattery health management as well as shelter medicine health considerations. Discusses controversial health and ethical issues in veterinary pediatrics, such as ear cropping, tail docking, declawing, and early spay/neuter surgery (including both pro and con positions). Includes the latest recommendations for nutritional care of healthy and "special needs" puppies and kittens as well as the post-parturient and nursing dam. Offers an easy-to-use, well-organized format for quick and easy access to the most relevant information.

Download or read book Feline Husbandry written by Niels C. Pedersen and published by Mosby. This book was released on 1991 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Feline Coronavirus Infection written by Andrew Douglas Regan and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Feline infectious peritonitis (FIP) is an untreatable and terminal disease of cats caused by systemic infection with a feline coronavirus termed feline infectious peritonitis virus (FIPV). This thesis investigates the cellular entry of FIPV in order to discover targets which may be of therapeutic value in treating this disease. This thesis demonstrates that FIPV utilizes the lectin DC-SIGN to enhance cellular uptake. This is significant because macrophages and dendritic cells, which express DC-SIGN at high levels, are infected by FIPV to initiate the disease process. This thesis also shows that FIPV activates the p38 MAPK signaling pathway in infected cells, and that this induces the overproduction of pro-inflammatory cytokines observed in cats with FIP. Finally this thesis demonstrates that feline coronaviruses require cathepsin cysteine proteases during entry to cleave and activate the viral spike protein. In addition, specific proteases are preferred over others depending on the pathogenicity of the virus. It is also shown that certain molecular inhibitors of cysteine proteases can block viral infection in primary feline cells, presumably by preventing cleavage of the spike protein during viral entry. These data highlight new therapeutic strategies for the treatment of FIP which will be discussed in the conclusion.

Download or read book August s Consultations in Feline Internal Medicine Volume 7 written by Susan E. Little and published by Elsevier Health Sciences. This book was released on 2015-12-14 with total page 1085 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stay current with cutting-edge information from the leading feline experts! August's Consultations in Feline Internal Medicine, Volume 7 takes the popular Current Therapy approach to the latest issues, advances, and therapies in feline care. The 103 new chapters are organized by body systems, making information easy to access, and include more than 800 new detailed photographs, diagrams, and MRI and ultrasound images. Discussions of scientific findings always emphasize clinical relevance and practical application. This edition addresses new topics ranging from feline obesity and food allergies to respiratory mycoplasmal infections. From feline expert Susan Little, with chapters written by more than 130 international specialists, this practical resource will be an invaluable addition to every small animal clinician's library. The Current Therapy format focuses on the latest advances in feline care and includes broad, traditional, and controversial subjects of real clinical importance. Clinically relevant approach is supported with scientific research and promotes practical, progressive clinical management. More than 130 world-renowned contributors provide expert insight across the full spectrum of feline internal medicine. Extensive references make it easy to find additional information about specific topics most important to your practice. 103 ALL-NEW chapters reflect the latest findings, reports, and evidence-based coverage of pressing topics such as: Managing respiratory mycoplasmal infections Continuous glucose monitoring in cats with diabetes Feline food allergy Stem cell therapy for chronic kidney disease Feline idiopathic cystitis Electrochemotherapy Current concepts in preventing and managing obesity Recognition and treatment of hypertensive crises Feline social behavior and personality NEW Emergency and Critical Care Medicine section contains 13 chapters covering complicated and serious internal medical problems. NEW! More than 800 colorful new images clarify concepts and demonstrate clinical examples.

Download or read book Feline Infectious Diseases written by Katrin Hartmann and published by CRC Press. This book was released on 2011-04-15 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all types of feline infectious diseases, including infections caused by viruses, bacteria, parasites and fungi. 199 clinical cases are presented randomly, as in practice, but the wide range of cases cover infectious diseases which affect all the organ systems of the cat. The illustrated clinical cases contain integrated questions a

Download or read book Learning from SARS written by Institute of Medicine and published by National Academies Press. This book was released on 2004-04-26 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of severe acute respiratory syndrome (SARS) in late 2002 and 2003 challenged the global public health community to confront a novel epidemic that spread rapidly from its origins in southern China until it had reached more than 25 other countries within a matter of months. In addition to the number of patients infected with the SARS virus, the disease had profound economic and political repercussions in many of the affected regions. Recent reports of isolated new SARS cases and a fear that the disease could reemerge and spread have put public health officials on high alert for any indications of possible new outbreaks. This report examines the response to SARS by public health systems in individual countries, the biology of the SARS coronavirus and related coronaviruses in animals, the economic and political fallout of the SARS epidemic, quarantine law and other public health measures that apply to combating infectious diseases, and the role of international organizations and scientific cooperation in halting the spread of SARS. The report provides an illuminating survey of findings from the epidemic, along with an assessment of what might be needed in order to contain any future outbreaks of SARS or other emerging infections.

Download or read book Feline Infectious Peritonitis written by Farina Mustaffa Kamal and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Feline infectious peritonitis (FIP), a fatal infectious disease of cats is one of the most serious threats faced by multiple cat environments. Several theories have emerged on the origin of feline infectious peritonitis virus (FIPV), which is a feline coronavirus (FCoV) and the etiologic agent for FIP. However, strong evidence links FIPV emergence to an 'internal mutation' of the relatively nonpathogenic feline enteric coronavirus (FECV). This mutation was presumed to originate from mutations in the feline coronavirus 3c gene. Our findings revealed an intact 3c gene for isolates of fecal origin of healthy cats, while the 3c gene sequence from FIP-diseased tissues revealed either an intact or a mutated 3c. Regardless of 3c gene sequence, coronaviruses from diseased tissues were capable of inducing FIP whereas fecal isolates from healthy cats were infectious but did not cause FIP thus confirming their FECV status. Also of note, an intact 3c gene is essential for intestinal replication by both biotypes and truncated 3c is not always responsible for the conversion of FECV to FIPV. A previous general assumption on FECV and FIPV cell/tissue tropism was also shown to be relative rather than absolute due to findings showing that FECV is able to infect macrophages but with much less efficiency. Since FIPV and FECV are constantly evolving within and between host cats, care must be taken on the interpretation of FCoV genetic comparisons particularly in the studies involving shelter cats, which usually are infected with many FCoV isolates of different origins. Specific pathogenic events that arise from conversion of FECV to FIPV in an individual feline host as well as a relationship between these events to host antiviral immune responses, remain to be elucidated. Experimental studies involving cats at either primary or rechallenge infections allow a thorough investigation of immune correlates responsible for FIP disease resistance. Analysis of virus-specific immune responses to either whole-killed virus or FIPV spike peptides did not reveal definitive antiviral T cell response correlates for resistance to the development of FIP during primary FIPVi3c2 infection of naive cats. Nevertheless, some trends including an earlier appearance of both CD4 and CD8 T cell responses, were noted in the cats showing either slow progression of disease (slow progressors) and or no evidence of FIP (survivors). In addition, antiviral T cell responses were evident at the later stage of primary infection in cats within these two outcome groups when compared to the absence of responses observed for cats showing rapid progression to FIP. Interestingly, a robust antiviral T cell response was observed in mesenteric lymph nodes harvested from slow progressors, but was absent in mesenteric nodes sampled from rapid progressors. Notably, a significantly higher antiviral T cell response was observed in survivor cats within three weeks after rechallenge with FIPVi3c2 when compared to responses observed during primary infection at the same time point. Consistent with findings in other reports, a reduction of lymphocyte and CD3 T cell numbers with comparable loss of CD4 and CD8 T cells were observed during primary FIPVi3c2 infection regardless of disease outcome or development of FIP. An expansion of the Treg subset was noted in the cats during rechallenge infection, particularly for survivor cats more recently exposed to FIPVi3c2. Along with these findings are preservation of functional T cell proliferative responses and the capability of T cells to secrete interleukin-2. An increased T cell production of TNF-[alpha] in response to mitogen stimulation was also observed for cats in both primary and rechallenge FIPVi3c2 infections suggesting a FIPV-induced pro-inflammatory state. Collectively, these findings implicate an importance for both immunoregulatory elements and preservation of T cell functions for resistance to FIP development, but do not provide strong evidence for a role of virus-specific T cell responses in FIP resistance during primary infection. Further investigation for additional host mechanisms that may also be critical for limiting the susceptibility of cats to this devastating disease is warranted and will be critical in the design of an efficacious FIPV vaccine strategies.

Download or read book Understanding Coronavirus written by Raul Rabadan and published by Cambridge University Press. This book was released on 2021-10-14 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the identification of the first cases of the coronavirus in December 2019, there has been a significant amount of confusion regarding the origin and spread of the so-called 'coronavirus', SARS-CoV-2, and the cause of the disease COVID-19. Conflicting messages from the media and officials across different countries and organizations, the abundance of disparate sources of information, unfounded conspiracy theories on the origins of the virus, unproven therapies, and inconsistent public health measures, have all served to increase anxiety in the population. Where did the virus come from? How is it transmitted? How does it cause disease? Is it like flu? What is a pandemic? In this concise and accessible introduction, a leading expert provides answers to these commonly asked questions. This revised and updated edition now also covers how the virus mutates, how important these mutations are, how vaccines work, and what we can expect in the near and long-term future.

Download or read book Aspects of the Pathogenesis and Biology of Feline Infectious Peritonitis Virus and Feline Enteric Coronavirus written by John Franklin Boyle and published by . This book was released on 1982 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Coronaviruses written by Hubert Laude and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronaviruses represent a major group of viruses of both molecular biological interest and clinical significance in animals and humans. During the past two decades, coronavirus research has been an expanding field and, since 1980, an international symposium was held every 3 years. We organized the yth symposium for providing an opportunity to assess important progresses made since the last symposium in Cambridge (U. K. ) and to suggest areas for future investigations. The symposium, held in September 1992, in Chantilly, France, was attended by 120 participants representing the majOlity of the laboratories engaged in the field. The present volume collects 75 papers which were presented during the yth symposium, thus providing a comprehensive view of the state of the art ofCoronavirology. The book is divided into 7 chapters. The first chapters gather reports dealing with genome organization, gene expression and structure-function relationships of the viral polypeptides. New sequence data about as yet poorly studied coronaviruses - canine coronavirus CCY and porcine epidemic diarrhoea virus PEDY - are presented. Increasing efforts appear to be devoted to the characterization of products of unknown function, encoded by various open reading frames present in the coronavirus genomes or delived from the processing of the large polymerase polyprotein. Due to the extreme size of their genome, the genetic engineering ofcoronavi\'uses through the production of full length cDNA clones is presently viewed as an unachievahle task.

Download or read book Feline Coronavirus and Antibodies in Effusions of Cats with Feline Infectious Peritonitis and Their Potential Cross reactivity with SARS CoV 2 written by 甘曜銘 and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Canine and Feline Infectious Diseases E BOOK written by Jane E. Sykes and published by Elsevier Health Sciences. This book was released on 2013-06-06 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: Canine and Feline Infectious Diseases is a practical, up-to-date resource covering the most important and cutting-edge advances in the field. Presented by a seasoned educator in a concise, highly visual format, this innovative guide keeps you current with the latest advances in this ever-changing field. 80 case studies illustrate the clinical relevance of the major infectious disease chapters. Well-organized Major Infectious Diseases chapters break down content by etiologic agent and epidemiology, clinical signs and their pathophysiology, physical examination findings, diagnosis, treatment and prognosis, immunity, prevention, and public health implications. Over 80 case studies illustrate how the information provided can be applied in everyday practice. Logical approach to laboratory diagnosis guides you through all the steps needed to accurately diagnose and treat viral, bacterial, fungal, protozoal, and algal diseases. Practical protocols provided by expert clinicians guide you in the management of canine and feline patients suspected to have infectious diseases, including handling, disinfection, isolation, and vaccination protocols. Over 500 full color images – geographic distribution maps, life cycle drawings, and hundreds of color photographs – visually illustrate and clarify complex issues. Easy-to-understand tables and boxes make content quickly accessible, eliminating the need to sort through dense text for critical information in the clinical setting.