Download or read book Experimental Approaches to Mammalian Embryonic Development written by Janet Rossant and published by Cambridge University Press. This book was released on 1988-11-25 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in the experimental analysis of the mammalian embryo are discussed from various scientific perspectives in this summary of major breakthroughs in embryonic development.
Download or read book Manipulation of Mammalian Development written by Ralph B.L. Gwatkin and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental biology has been transformed recently by discoveries in the fields of molecular biology, cell biology, and immunology. New ways of manip ulating mammalian development are uncovering control mechanisms and ena bling us to apply them in solving practical problems in animal production and human health. This book outlines some of these new manipulations and how they have contributed to the present state of developmental biology. Chapter 1 describes gene transfer by micro injection of cloned recombinant DNA into zygotes. Although the factors that affect transformation frequencies and integration sites are still unknown, such techniques offer a number of exciting prospects. Research models for human disease coula be artificially created and desirable characteristics in agricultural animals could be - hanced. . The theme of cell-to-cell transfer is continued in Chapters 2 and 3. Chapter 2 describes pronuclear transplantation by Sendai virus-induced fusion of the karyoplast with the enucleated embryo. Using this procedure, it has been dem onstrated that both male and female genomes are essential for normal develop ment, although the reason for this is not yet understood. Chapter 3 describes studies on the fusion of whole oocytes. .
Download or read book Methods in Mammalian Reproduction written by Joseph C. Daniel and published by . This book was released on 1978 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Mammalian Reproduction ...
Download or read book Cell Fate in Mammalian Development written by and published by Academic Press. This book was released on 2018-02-21 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Fate in Mammalian Development, Volume 128, the latest release in the Current Topics in Developmental Biology series, provides reviews on cell fate in mammalian development. Each chapter is written by an international board of authors, with this release including sections on the Specification of extra-embryonic lineages during mouse pre-implantation development, Cell polarity and fate specification, The circuitry that drives trophectoderm identity, Breaking symmetry and the dynamics of transcription factors directing cell fate specification, Mechanics and cell fate, How physical properties of cells change in development and their effect on cell fate decisions, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Includes new sections on the specification of extra-embryonic lineages during mouse pre-implantation development, cell polarity and fate specification, the circuitry that drives trophectoderm identity, and more - Presents the latest release in the Current Topics in Developmental Biology series
Download or read book Methods in Mammalian Reproduction written by Joseph C. Jr. Daniel and published by Elsevier. This book was released on 2012-12-02 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Mammalian Reproduction presents some of the techniques for manipulating, analyzing, observing, testing, and generally experimenting with mammalian mothers and their gametes and embryos. Mammalian reproduction involves an intimate relationship between mother and embryo. The first 18 chapters are arranged in an order that follows a developmental sequence from oocyte to fetal organs and the remaining seven chapters deal with the maternal side of the relationship. With strong focus on laboratory rodents and lagomorphs, the book starts with an introduction to in vitro oocyte maturation and experimental production of mammalian parthenogenetic. It goes on to describe the microtechniques in pre-implantation of embryos, production of chimeras, techniques for early embryonic tissue separation, mammalian embryo preservation by freezing, and in vitro development of whole mouse embryos beyond the implantation stage. Chapters 11-15 discuss the in vitro implantation of mouse blastocysts, advances in rabbit embryo and in large mammal embryo cultures, embryo transfer in large domestic mammals, and manipulation of marsupial embryos and pouch young. The following chapters cover reproduction experiments using marsupials, domestic farm species, and primates including humans. Finally, the concluding chapters tackle the use of amniocentesis in prenatal diagnosis, collection and analysis of female genital tract secretions, analysis of antifertility action of intrauterine devices, and surgical induction of endometriosis. This book will be helpful to students, teachers, researchers, and clinical researchers who demand for more and better procedures for analysis of mammalian reproduction.
Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.
Download or read book Notes on the Application of Experimental Methods Upon Mammalian Embryos written by John Spangler Nicholas and published by . This book was released on 1925 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Early Development of Mammals written by British Society for Developmental Biology and published by CUP Archive. This book was released on 1975-08-21 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mammalian Development written by Patrick P. L. Tam and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A subject collection from Cold Spring Harbor perspectives in biology."
Download or read book New Approaches to the Evaluation of Abnormal Embryonic Development written by Hans Joachim Merker and published by . This book was released on 1975 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Laboratory Guide to the Mammalian Embryo written by David K. Gardner and published by Oxford University Press. This book was released on 2004-01-08 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Never before has there been such a comprehensive book of protocols. This compendium offers a full range of research techniques-from cell culture, to biochemical, to microscopic and genetic. More focused books, like Cold Spring Harbor's Manipulating the Mouse Embryo, are similar though more narrow in scope. This book will appeal to a broad range of researchers, from basic experimental scientists to clinical and animal scientists.
Download or read book Postimplantation Mammalian Embryos written by Andrew John Copp and published by Oxford University Press, USA. This book was released on 1990 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide for researchers, technicians, and students in mammalian embryology, developmental biology, and the pharmaceutical industry to new methods of observing, manipulating, and analyzing implanted embryos. The topics include exo utero surgery, the morphological stages of postimplantation embryonic development, extracting macromolecules, and teratogen testing. Annotation copyrighted by Book News, Inc., Portland, OR
Download or read book Cytogenetics of Mammalian Embryonic Development written by Andreĭ Pavlovich Dyban and published by Oxford University Press, USA. This book was released on 1987 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromosome anomalies are a major cause of embryonic mortality as well as of mental and physical defects, but until very recently it has been almost impossible to understand the underlying causal mechanisms linking chromosomes and development. In this book, two eminent biomedical scientists explain how laboratory experiments with mice are finally revealing the molecular basis of gene expression in early development. Comprehensive and up-to-date, Dyban and Baranov's work is the first attempt to review the whole field by bringing together the important research being done in the United States, the Soviet Union, Britain, and Germany.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Methods in Experimental Embryology of the Mouse written by Keen Alexander Rafferty and published by Johns Hopkins University Press. This book was released on 1970 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Examining the State of the Science of Mammalian Embryo Model Systems written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-08-31 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the science of mammalian embryo model systems. The workshop, which took place on January 17, 2020, featured a combination of presentations, panels, and general discussions, during which panelists and participants offered a broad range of perspectives. Participants considered whether embryo model systems - especially those that use nonhuman primate cells - can be used to predict the function of systems made with human cells. Presentations provided an overview of the current state of the science of in vitro development of human trophoblast. This publication summarizes the presentation and discussion of the workshop.
