Download or read book Perspectives in Receptor Research written by Dario Giardina and published by Elsevier. This book was released on 1996-06-07 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perspectives in Receptor Research

Download or read book Perspectives in Medicinal Chemistry written by Bernard Testa and published by Wiley-VCH. This book was released on 1993 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book XIVth International Symposium on Medicinal Chemistry written by F. Awouters and published by Elsevier. This book was released on 1997-09-12 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaso-occlusive disorders including unstable angina, myocardial infarction, transient ischemic attacks, stroke and peripheral artery disease remain the major sources of morbidity and mortality in western civilization. Platelet activation and resulting platelet aggregation play a major role in the pathogenesis of these thromboembolic diseases. Recognition of the contribution of platelets to the pathophysiology of cardiovascular disease has provided impetus for the continued search for new antiplatelet agents. Hence, over the past two decades many strategies have been evaluated in the search for efficacious mechanisms to reduce platelet function. The medical need for more efficacious antithrombotic drugs and the growing understanding of the role of platelets in vascular injury have catalyzed the extensive evaluation of novel approaches to control platelet function. Along these lines, the volume therefore provides an in-depth assessment of ongoing clinical trials, new and clinically established agents, and other developments in this rapidly developing field.

Download or read book Computer Assisted Lead Finding and Optimization written by Han van de Waterbeemd and published by Wiley-VCH. This book was released on 1997-07-14 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer-assisted techniques are well-integrated in modern drug discovery and used for the finding of new leads, the optimization of receptor or enzyme affinity, as well as of pharmacokinetic and physicochemical properties. In this book an account is found of current strategies used in computer-assisted drug design. Important topics include progress in chemometrics, molecular modeling and three-dimensional QSAR approaches. Relatively new mathematical methods such as genetic algorithms or artificial neural networks and fuzzy logic have found their application in rational molecular design. As is amply illustrated, based on recent developments in these disciplines, important progress has been made in lead finding strategies. This is of great importance to the pharmaceutical industry. Thus, all scientists investigating quantitative structure-activity relationships in their broadest sense, in medicinal, agricultural, or environmental chemistry will benefit from this book.

Download or read book Chemometrics Applications and Research written by Andrew G. Mercader and published by CRC Press. This book was released on 2016-03-30 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important new book provides innovative material, including peer-reviewed chapters and survey articles on new applied research and development, in the scientifically important field of QSAR in medicinal chemistry. QSAR is a growing field because available computing power is continuously increasing, QSAR's potential is enormous, limited only by

Download or read book Bioactive Heterocycles written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Abnormal Laboratory Results written by Robert Dunstan and published by McGraw-Hill/Spanish Imports. This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abnormal Laboratory Results is a compilation of articles from Australian Prescriber journal on the interpretation of abnormal laboratory results. Includes HIV and blood clotting tests, new units of measure and new technologies. Enables Pathologists, general practitioners and related healthcare professionals to remain abreast of the latest developments in the interpretation of abnormal laboratory results

Download or read book Solid State NMR written by Klaus Müller and published by John Wiley & Sons. This book was released on 2021-08-23 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid State NMR A thorough and comprehensive textbook covering the theoretical background, experimental approaches, and major applications of solid-state NMR spectroscopy Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful non-destructive technique capable of providing information about the molecular structure and dynamics of molecules. Alongside solution-state NMR, a well-established technique to study chemical structures and investigate physico-chemical properties of molecules in solutions, solid-state NMR (SSNMR) offers many exciting possibilities for the analysis of solid and soft materials across scientific fields. SSNMR shows unique capabilities for a detailed investigation of structural and dynamic properties of materials over wide space and time ranges. For this reason, and thanks to significant advances in the past several years, the application of SSNMR to materials is rapidly increasing in disciplines such as chemistry, physics, and materials and life sciences. Solid State NMR: Principles, Methods, and Applications offers a systematic introduction to the theory, methodological concepts, and major experimental methods of SSMR spectroscopy. Exploring the unique potential of SSNMR for the structural and dynamic characterization of soft and either amorphous or crystalline solid materials, this comprehensive textbook provides foundational knowledge and recent developments of SSNMR, covering physical and theoretical background, experimental methods, and applications to pharmaceuticals, polymers, inorganic and hybrid materials, liquid crystals, and model membranes. Written by two expert authors to ensure a clear and consistent presentation of the subject, this textbook: Includes a brief introduction to the historical aspects and broad theoretical background of solid-state NMR spectroscopy Provides helpful illustrations to explain the various SSNMR concepts and methods Features accessible descriptive text with self-consistent use of quantum mechanics Covers the experimental aspects of SSNMR spectroscopy and in particular a description of many useful pulse sequences Contains references to relevant literature Solid State NMR: Principles, Methods, and Applications is the ideal textbook for university courses on SSNMR, advanced spectroscopies, and a valuable single-volume reference for spectroscopists, chemists, and researchers in the field of materials.

Download or read book Flavins and Flavoproteins written by Stefan Weber and published by Humana. This book was released on 2014-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Flavins and Flavoproteins: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to study flavins and flavoproteins. These include review style methods and protocols to exemplify the variety, the power and the success of modern techniques and methods in application to flavoproteins. Part I of this Volume covers general properties, syntheses and applications of free flavins as well as its analogs and flavoproteins. Part II covers characterizations of flavins and flavoproteins using modern experimental techniques as well as theoretical methods. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Flavins and Flavoproteins: Methods and Protocols aids scientists in continuing to tackle the countless questions that need to be answered to more fully comprehend the vast diversity and specificity of flavin-governed biological processes.

Download or read book Esercitazioni di chimica farmaceutica e tossicologica 1 written by Fulvio Rubessa and published by . This book was released on 1978 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: