Download or read book Analysis of Cancer Risks in Populations Near Nuclear Facilities written by National Research Council and published by National Academies Press. This book was released on 2012-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.

Download or read book Cancer Epidemiology written by Isabel dos Santos Silva and published by IARC. This book was released on 1999 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: A basic textbook addressed to medical and public health students, clinicians, health professionals, and all others seeking to understand the principles and methods used in cancer epidemiology. Written by a prominent epidemiologist and experienced teacher at the London School of Hygiene and Tropical Medicine, the text aims to help readers become competent in the use of basic epidemiological tools and capable of exercising critical judgment when assessing results reported by others. Throughout the text, a lively writing style and numerous illustrative examples, often using real research data, facilitate an easy understanding of basic concepts and methods. Information ranges from an entertaining account of the origins of epidemiology, through advice on how to overcome some of the limitations of survival analysis, to a checklist of questions to ask when considering sources of bias. Although statistical concepts and formulae are presented, the emphasis is consistently on the interpretation of the data rather than on the actual calculations. The text has 18 chapters. The first six introduce the basic principles of epidemiology and statistics. Chapters 7-13 deal in more depth with each of the study designs and interpretation of their findings. Two chapters, concerned with the problems of confounding and study size, cover more complex statistical concepts and are included for advanced study. A chapter on methodological issues in cancer prevention gives examples of epidemiology's contribution to primary prevention, screening and other activities for early detection, and tertiary prevention. The concluding chapters review the role of cancer registries and discuss practical considerations that should be taken into account in the design, planning, and conduct of any type of epidemiological research.

Download or read book Critical Appraisal of Epidemiological Studies and Clinical Trials written by Mark Elwood and published by OUP Oxford. This book was released on 2007-02-22 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a logical system of critical appraisal, to allow readers to evaluate studies and to carry out their own studies more effectively. This system emphasizes the central importance of cause and effect relationships. Its great strength is that it is applicable to a wide range of issues, and both to intervention trials and observational studies. This system unifies the often different approaches used in epidemiology, health services research, clinical trials, and evidence-based medicine, starting from a logical consideration of cause and effect. The author's approach to the issues of study design, selection of subjects, bias, confounding, and the place of statistical methods has been praised for its clarity and interest. Systematic reviews, meta-analysis, and the applications of this logic to evidence-based medicine, knowledge-based health care, and health practice and policy are discussed. Current and often controversial examples are used, including screening for prostate cancer, publication bias in psychiatry, public health issues in developing countries, and conflicts between observational studies and randomized trials. Statistical issues are explained clearly without complex mathematics, and the most useful methods are summarized in the appendix. The final chapters give six applications of the critical appraisal of major studies: randomized trials of medical treatment and prevention, a prospective and a retrospective cohort study, a small matched case-control study, and a large case-control study. In these chapters, sections of the original papers are reproduced and the original studies placed in context by a summary of current developments.

Download or read book Public Health Systems and Emerging Infections written by Institute of Medicine and published by National Academies Press. This book was released on 2000-06-08 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Forum on Emerging Infections was created in 1996 in response to a request from the Centers for Disease Control and Prevention and the National Institutes of Health. The goal of the forum is to provide structured opportunities for representatives from academia, industry, professional and interest groups, and government to examine and discuss scientific and policy issues that relate to research, prevention, detection, and management of emerging infectious diseases. A critical part of this mission has been the convening of a series of workshops. Public Health Systems and Emerging Infections summarizes the fourth in a series of five workshops. With a focus on our knowledge and understanding of the role of private and public health sectors in emerging infectious disease surveillance and response, the participants explored the effects of privatization of public health laboratories and the modernization of public health care. The issues discussed included epidemiological investigation, surveillance, communication, coordination, resource allocations, and economic support.

Download or read book Epidemiologic Methods written by Noel S. Weiss and published by Oxford University Press. This book was released on 2014-07-03 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of Epidemiologic Methods offers a rigorous introduction to the concepts and tools of epidemiologic research. Aimed chiefly at future epidemiologists, the book offers clear descriptions, practical examples, and question/answer sections for each of the science's key concepts. Authored by two award-winning epidemiology instructors, this book is ideally suited for use as a text in a graduate-level course sequence in epidemiologic methods. The book's chapters are organized around three main themes: general concepts and tools of epidemiology; major study designs; and special topics, including screening, outbreak investigations, and use of epidemiology to evaluate policies and programs. With additional exercises at the end of each chapter and expanded attention to topics such as confounding, this new edition of Epidemiologic Methods is an indispensable resource for the next generation of epidemiologic study.

Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.

Download or read book Epidemiologic Methods in Physical Activity Studies written by I-Min Lee and published by Oxford University Press. This book was released on 2009 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book provides information regarding epidemiologic methods used in studies of physical activity. It is intended for use by students and researchers in physical activity and in public health, and by researchers and professionals using physical activity data (e.g., exercise physiologists and health economists). Additionally, those interested in physical activity and health, who want to understand and appropriately interpret the results of physical activity studies (e.g., physicians and journalists), may also find the book useful."--BOOK JACKET.

Download or read book Epidemiology for the Uninitiated written by David Coggon and published by John Wiley & Sons. This book was released on 2009-02-05 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: This perennial bestseller is an ideal introductions to epidemiology in health care. The fifith editon retains the book's simplicity and brevity, at the same time providing the reader with the core elements of epidemiology needed in health care practice and research. The text has been revised throughout, with new examples introduced to bring the book right up to date.

Download or read book Epidemiological Studies written by Alan J. Silman and published by . This book was released on 2018-10-25 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supplemented throughout by appropriate examples and helpful hints, this practical guide to the design, conduct, analysis and interpretation of epidemiological studies is designed to support and encourage new students as well as clinical professionals. --! From publisher's description.

Download or read book Epidemiologic Studies of Veterans Exposed to Depleted Uranium written by Institute of Medicine and published by National Academies Press. This book was released on 2008-09-11 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: Depleted uranium, a component of some weapons systems, has been in use by the U.S. military since the 1991 Gulf War. Military personnel have been exposed to depleted uranium as the result of friendly fire incidents, cleanup and salvage operations, and proximity to burning depleted uranium-containing tanks and ammunition. Under a Congressional mandate, the Department of Defense sought guidance from the Institute of Medicine in evaluating the feasibility and design of an epidemiologic study that would assess health outcomes of exposure to depleted uranium. The study committee examined several options to study health outcomes of depleted uranium exposure in military and veteran populations and concluded that it would be difficult to design a study to comprehensively assess depleted uranium-related health outcomes with currently available data. The committee further concluded that the option most likely to obtain useful information about depleted uranium-related health outcomes would be a prospective cohort study if future military operations involve exposure to depleted uranium. The book contains recommendations aimed at improving future epidemiologic studies and identifying current active-duty military personnel and veterans with potential DU exposure.

Download or read book Disaster Epidemiology written by Jennifer Horney and published by Academic Press. This book was released on 2017-10-31 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disaster Epidemiology: Methods and Applications applies the core methods of epidemiological research and practice to the assessment of the short- and long-term health effects of disasters. The persistent movement of people and economic development to regions vulnerable to natural disasters, as well as new vulnerabilities related to environmental, technological, and terrorism incidents, means that in spite of large global efforts to reduce the impacts and costs of disasters, average annual expenditures to fund rebuilding from catastrophic losses is rising faster than either population or the gross world product. Improving the resilience of individuals and communities to these natural and technological disasters, climate change, and other natural and manmade stressors is one of the grand challenges of the 21st century. This book provides a guide to disaster epidemiology methods, supported with applications from practice. It helps researchers, public health practitioners, and governmental policy makers to better quantify the impacts of disaster on the health of individuals and communities to enhance resilience to future disasters. Disaster Epidemiology: Methods and Applications explains how public health surveillance, rapid assessments, and other epidemiologic studies can be conducted in the post-disaster setting to prevent injury, illness, or death; provide accurate and timely information for decisions makers; and improve prevention and mitigation strategies for future disasters. These methods can also be applied to the study of other types of public health emergencies, such as infectious outbreaks, emerging and re-emerging diseases, and refugee health. This book gives both the public health practitioner and researcher the tools they need to conduct epidemiological studies in a disaster setting and can be used as a reference or as part of a course. - Provides a holistic perspective to epidemiology with an integration of academic and practical approaches - Showcases the use of hands-on techniques and principles to solve real-world problems - Includes contributions from both established and emerging scholars in the field of disaster epidemiology

Download or read book Epidemiological Research Methods written by Donald R. McNeil and published by John Wiley & Sons. This book was released on 1996-08-06 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concepts of epidemiology, the science that uses statistical methods to investigate associations between risk factors and disease outcomes in human populations, are developed using examples involving real data from published studies. The relevant statistical methods are developed systematically to provide an integrated approach to observational and experimental studies. After covering basic measurement, study design, and study credibility issues, the author continues with basic statistical methods and techniques for adjusting risk estimates for confounders. Statistical models including logistic regression and the proportional hazards model for survival analysis are explained in detail in the following chapters, concluding with an explanation of the general methods for determining the sample size and power requirements for an epidemiological study. Taking advantage of the power, accessibility and user-friendliness of modern computer packages, the author uses a variety of interesting data sets and graphical displays to illustrate the methods. Epidemiological Research Methods will be of interest to students and research workers who need to learn and appreciate modern approaches to the subject. Without unnecessary emphasis on mathematics or theory, the book will enable the reader to gain a greater level of understanding of the underlying methods than is normally provided in books on epidemiology.

Download or read book Epidemiology written by Mark Woodward and published by CRC Press. This book was released on 2013-12-19 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly praised for its broad, practical coverage, the second edition of this popular text incorporated the major statistical models and issues relevant to epidemiological studies. Epidemiology: Study Design and Data Analysis, Third Edition continues to focus on the quantitative aspects of epidemiological research. Updated and expanded, this edition shows students how statistical principles and techniques can help solve epidemiological problems. New to the Third Edition New chapter on risk scores and clinical decision rules New chapter on computer-intensive methods, including the bootstrap, permutation tests, and missing value imputation New sections on binomial regression models, competing risk, information criteria, propensity scoring, and splines Many more exercises and examples using both Stata and SAS More than 60 new figures After introducing study design and reviewing all the standard methods, this self-contained book takes students through analytical methods for both general and specific epidemiological study designs, including cohort, case-control, and intervention studies. In addition to classical methods, it now covers modern methods that exploit the enormous power of contemporary computers. The book also addresses the problem of determining the appropriate size for a study, discusses statistical modeling in epidemiology, covers methods for comparing and summarizing the evidence from several studies, and explains how to use statistical models in risk forecasting and assessing new biomarkers. The author illustrates the techniques with numerous real-world examples and interprets results in a practical way. He also includes an extensive list of references for further reading along with exercises to reinforce understanding. Web Resource A wealth of supporting material can be downloaded from the book’s CRC Press web page, including: Real-life data sets used in the text SAS and Stata programs used for examples in the text SAS and Stata programs for special techniques covered Sample size spreadsheet

Download or read book Epidemiology Foundations written by Peter J. Fos and published by John Wiley & Sons. This book was released on 2010-11-11 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by Peter J. Fos an expert in epidemiology with more than twenty years teaching experience Epidemiology Foundations offers an ideal introduction to the theory and practice of public health epidemiology. This important text discusses both the historical perspective and future trends of epidemiology, reviews health and disease, and explains how they are measured. The book's overview of epidemiological studies shows how they are used in practice. Epidemiology Foundations takes a social and community perspective and includes information about global diseases and epidemics. Emphasis on concepts such as population health, social determinants, and global health make this book especially interesting and accessible to those new to the subject. Each chapter is supplemented with problem-solving exercises and research assignments to aid readers in understanding its epidemiology principles. Reflecting and expanding on recommendations of the Association of American Colleges and Universities, Epidemiology Foundations is the ideal text for any course introducing epidemiology in public health.

Download or read book Epidemiologic Research written by David G. Kleinbaum and published by John Wiley & Sons. This book was released on 1991-01-16 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiologic Research Principles and Quantitative Methods DavidG. Kleinbaum, Ph.D. Lawrence L. Kupper. Ph.D. Hal Morgenstern,Ph.D. Epidemiologic Research covers the principles and methodsof planning, analysis and interpretation of epidemiologic researchstudies. It supplies the applied researcher with the mostup-to-date methodological thought and practice. Specifically, thebook focuses on quantitative (including statistical) issues arisingfrom epidemiologic investigations, as well as on the questions ofstudy design, measurement and validity. EpidemiologicResearch emphasizes practical techniques, procedures andstrategies. It presents them through a unified approach whichfollows the chronology of issues that arise during theinvestigation of an epidemic. The book's viewpoint ismultidisciplinary and equally useful to the epidemiologicresearcher and to the biostatistician. Theory is supplemented bynumerous examples, exercises and applications. Full solutions aregiven to all exercises in a separate solutions manual. Importantfeatures * Thorough discussion of the methodology of epidemiologicresearch * Stress on validity and hence on reliability * Balanced approach, presenting the most important prevailingviewpoints * Three chapters with applications of mathematical modeling

Download or read book Critical Appraisal of Epidemiological Studies and Clinical Trials written by Mark Elwood and published by Oxford University Press. This book was released on 2017-02-23 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since publication of the first three editions of this hugely successful book, systematic methods of critical appraisal have been accepted as central to healthcare provision, both in critical applications and in a wider health services and community perspective. This new edition builds on the work of the previous editions by presenting a fully updated and accessible system of critical appraisal applicable to clinical, epidemiological, and public health studies, and related fields. The book outlines the systematic review process for the establishment of causal effect within single and multiple studies. Focusing primarily on study design, it covers randomized and non-randomized trials, cohort studies, case-control studies, and surveys, showing the presentation of results including person-time and survival analysis, and issues in the selection of subjects. It then describes the process of detection and assessment of selection biases, observation bias, confounding, chance variation, and how to determine internal validity and external validity (generalizability). Statistical methods are presented in an accessible way, illustrating applications to each study design. Positive features of causation including strength, dose-response, and consistency are also discussed. The final chapters provide six examples of critical appraisals of major studies, encompassing randomized trials, prospective and retrospective cohort studies, and case-control studies. Statistical issues are explained clearly without complex mathematics, and the most useful methods are summarized in the appendix, each with a worked example. Each main chapter includes self-test questions, with answers provided, making the book ideally suited to readers with no prior epidemiological or statistical knowledge. Developed over four editions, Critical Appraisal of Epidemiological Studies and Clinical Trials is an invaluable aid to the effective assessment of new studies in epidemiology, public health, research methods, evidence-based methods, clinical medicine, and environmental health; making it essential reading for postgraduates, practitioners, and policymakers in these fields.