Download or read book Entry and Early Infection of Non segmented Negative Sense RNA Viruses written by Jean Mawuena Branttie and published by . This book was released on 2021 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Molecular Virology written by Susanne Modrow and published by Springer. This book was released on 2013-09-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book gives a comprehensive overview on the knowledge of virus infection relevant for humans and animals. For each virus family the molecular details of the virus particle and the viral replication cycle are described. In the case of virus types with relevance for human and/or animal health the data on molecular biology, genetics and virus-cell interaction are combined with those concerning, pathogenesis, epidemiology, clinics, prevention and therapy.

Download or read book Viruses and Human Disease written by Ellen G. Strauss and published by Elsevier. This book was released on 2007-09-21 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss’ virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease. Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia Further reading sections at the end of each chapter make it easy find key references World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text

Download or read book Negative Strand RNA Virus written by Ming Luo and published by World Scientific. This book was released on 2011 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ch. 1. Overview of negative-strand RNA viruses / Biao He -- ch. 2. Rhabdovirus entry into the host cell / Aurelie Albertini and Yves Gaudin -- ch. 3. Virus entry : parainfluenza viruses / Masato Tsurudome -- ch. 4. What controls the distinct VSV RNA synthetic processes of replication and transcription? / Gail Williams Wertz, Summer E. Galloway and Djamila Harouaka -- ch. 5. mRNA capping by vesicular stomatitis virus and other related viruses / Tomoaki Ogino and Amiya K. Banerjee -- ch. 6. Structural disorder within the measles virus nucleoprotein and phosphorprotein : functional implications for transcript and replication / Sonia Longhi -- ch. 7. Biochemical and structural insights into vesicular stomatitis virus transcription / Amal A. Rahmeh and Sean P.J. Whelan -- ch. 8. Transcription of vesicular stomatitis virus RNA genome / Debasis Panda and Asit K. Pattnaik -- ch. 9. Assembly of vesicular stomatitis virus / Ming Luo, Todd J. Green and Z. Hong Zhou -- ch. 10. Paramyxovirus budding mechanisms / Megan S. Harrison, Takemasa Sakaguchi and Anthony P . Schmitt -- ch. 11. Virus-host interaction by members of the family rhabdoviridae and filoviridae / Douglas S. Lyles -- ch. 12. Paramyxovirus and rig-like helicases : a complex molecular interplay driving innate immunity / Denis Gerlier -- ch. 13. The molecular and cellular biology of emerging bunyaviruses / John N. Barr -- ch. 14. Ebolaviruses : what we know and where we are on potential therapeutics / Peter Halfmann, Gabriele Neumann and Yoshihiro Kawaoak

Download or read book Essential Human Virology written by Jennifer Louten and published by Academic Press. This book was released on 2022-05-28 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Human Virology, Second Edition focuses on the structure and classification of viruses, virus transmission and virus replication strategies based upon type of viral nucleic acid. Several chapters focus on notable and recognizable viruses and the diseases caused by them, including influenza, HIV, hepatitis viruses, poliovirus, herpesviruses and emerging and dangerous viruses. Additionally, how viruses cause disease (pathogenesis) is highlighted, along with discussions on immune response to viruses, vaccines, anti-viral drugs, gene therapy, the beneficial uses of viruses, research laboratory assays and viral diagnosis assays. Fully revised and updated with new chapters on coronaviruses, nonliving infectious agents, and notable non-human viruses, the book provides students with a solid foundation in virology. Focuses on human diseases and the cellular pathology that viruses cause Highlights current and cutting-edge technology and associated issues Presents real case studies and current news highlights in each chapter Features dynamic illustrations, chapter assessment questions, key terms, and a summary of concepts, as well as an instructor website with lecture slides, a test bank and recommended activities Updated and revised, with new chapters on coronaviruses, nonliving infectious agents, and notable non-human viruses

Download or read book Coronaviruses written by Helena J. Maier and published by Humana. This book was released on 2021-09-08 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed new edition provides a comprehensive collection of protocols applicable to all members of the Coronavirinae sub-family currently and that are also transferrable to other fields of virology. Beginning with a section on detection, discovery, and evolution, the volume continues with coverage of propagation and titration of coronaviruses, genome manipulation, study of virus-host interactions, as well as imaging coronavirus infections. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Coronaviruses: Methods and Protocols, Second Edition serves as a valuable guide to researchers working to identify and control viruses with increased potential to cross the species barrier and to develop the diagnostics, vaccines, and antiviral therapeutics that are required to manage future outbreaks in both humans and animals.

Download or read book Peste des Petits Ruminants Virus written by Muhammad Munir and published by Springer. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a timely and comprehensive review of essential research on Peste des Petits Ruminants Virus (PPRV), ranging from its historical distribution, molecular epidemiology, genome structure, viral proteins, immunity, viral pathogenesis, clinical and molecular diagnosis to advances in vaccine developments and future challenges. PPRV, a Rinderpest-like virus, is the causative agent of one of the most rapidly emerging viral diseases among domestic small ruminants, and the host spectrum has now been expanded to wild small ruminants and camels. With the global eradication of the first livestock disease, Rinderpest, attention is now turning to repeating the procedure for PPR. Each of the book’s 13 chapters is dedicated to a specific topic, providing up-to-date literature and discussions by renowned scientists who have made seminal contributions in their respective fields of expertise. Special emphasis has been placed on the analysis of different global efforts to eradicate PPR. This book offers a valuable reference source for virologists, field veterinarians, infection and molecular biologists, immunologists, scientists in related fields and veterinary school libraries.

Download or read book RNA Viruses written by Decheng Yang and published by World Scientific. This book was released on 2009 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive book on human/animal gene responses to RNA viral infections, including prevalent, emerging and re-emerging RNA viruses such as HIV, SARS-CoV, West Nile virus, influenza virus and many others. Human gene responses are reviewed by leading virologists worldwide in the following aspects: (i) the altered gene expression profiles at the transcriptional and translational levels detected with cutting-edge technologies such as cDNA microarray and proteomics; (ii) host innate and adapted immune responses to viral replication in target organs; (iii) virus-activated signal transduction pathways in cell survival, apoptosis and autophagosomal pathways; and (iv) the small interfering RNA/microRNA-mediated gene silencing pathway, a recently characterized new host defense mechanism against viral infection. Organized into 29 highly accessible and well-illustrated chapters, this volume explores state-of-the-art knowledge of the molecular mechanisms of RNA virus infection and host?virus interactions. This comprehensive compilation of the altered gene expression profiles and signal transduction pathways in host cells in response to the majority of human/animal RNA viruses opens new directions for basic and clinical research on viral pathogenesis, and also provides valuable biomarkers for researchers to select gene targets in the development of diagnostic tests and antiviral therapeutics for a number of infectious diseases.

Download or read book Fields Virology Emerging Viruses written by Peter M. Howley and published by Lippincott Williams & Wilkins. This book was released on 2020-02-11 with total page 2597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: Emerging Viruses, 7th Edition covers recent changes in emerging viruses, providing new or extensively revised chapters that reflect these advances in this dynamic field.

Download or read book Fenner and White s Medical Virology written by Christopher J. Burrell and published by Academic Press. This book was released on 2016-11-09 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology. Features updated and expanded coverage of pathogenesis and immunity Contains the latest laboratory diagnostic methods Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control

Download or read book Viral Proteases and Their Inhibitors written by Satya Prakash Gupta and published by Academic Press. This book was released on 2017-07-03 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents. Provides comprehensive, state-of-the-art coverage of virus infections, the virus lifecycle, and mechanisms of protease inhibition Analyzes structure-activity relationships of inhibitors of each viral protease Presents an in-depth view of the structure and function of viral proteases

Download or read book Viral Polymerases written by Satya Prakash Gupta and published by Academic Press. This book was released on 2018-10-29 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral Polymerases: Structures, Functions and Roles as Antiviral Drug Targets presents in-depth study information on the structure and functions of polymerases and their roles in the lifecycle of viruses, and as drug targets. Viral polymerases constitute a vital component in the lifecycle of many viruses, such as human immunodeficiency virus (HIV), hepatitis viruses, influenza virus, and several others. They are essentially required for the replication of viruses. Thus, the polymerases that can be found in viruses (called viral polymerases) represent favorable targets for the design and development of antiviral drugs. Provides comprehensive, state-of-the-art coverage on virus infections, the virus lifecycle, and mechanisms of polymerase inhibition Analyzes the structure-activity relationships of inhibitors of each viral polymerase Presents a consistent and comprehensive coverage of all aspects of viral polymerases, including structure, function and their role as antiviral drug targets

Download or read book Ranaviruses written by Matthew J. Gray and published by Springer. This book was released on 2015-05-01 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book on ranaviruses. Ranaviruses are double-stranded DNA viruses that cause hemorrhagic disease in amphibians, reptiles, and fish. They have caused mass die-offs of ectothermic vertebrates in wild and captive populations around the globe. There is evidence that this pathogen is emerging and responsible for population declines in certain locations. Considering that amphibians and freshwater turtles are suitable hosts and the most imperiled vertebrate taxa in the world, ranaviruses can have significant impacts on biodiversity and ecosystem function. Additionally, many fish that are raised in aquaculture facilities and traded internationally are suitable hosts; thus, the potential economic impact of ranaviruses is significant. Ranaviruses also serve as a model for replication and gene function of large double-stranded DNA viruses. There is an urgent need to assemble the contemporary information on ranaviruses and provide guidance on how to assess their threats in populations. Through the Global Ranavirus Consortium, 24 experts from six countries were organize to write this volume, the first book on ranaviruses. The book begins with a discussion on the global extent of ranaviruses, case histories of infection and disease in ectothermic vertebrates, and current phylogeny. Basic principles of ranavirus ecology and evolution are covered next, with a focus on host-pathogen interactions and how the virus emerges in its environment. There are two chapters that will discuss the molecular biology of ranaviruses, host response to infection, and the genes responsible for immune system evasion. One chapter establishes standards for testing for infection and diagnosing ranaviral disease. The book ends by providing guidance on how to design ranavirus surveillance studies and analyze data to determine risk, and discussing the role of the Global Ranavirus Consortium in organizing research and outreach activities.

Download or read book Viruses Essential Agents of Life written by Günther Witzany and published by Springer Science & Business Media. This book was released on 2012-11-13 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: A renaissance of virus research is taking centre stage in biology. Empirical data from the last decade indicate the important roles of viruses, both in the evolution of all life and as symbionts of host organisms. There is increasing evidence that all cellular life is colonized by exogenous and/or endogenous viruses in a non-lytic but persistent lifestyle. Viruses and viral parts form the most numerous genetic matter on this planet.

Download or read book Virus Structure written by and published by Elsevier. This book was released on 2003-10-02 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virus Structure covers the full spectrum of modern structural virology. Its goal is to describe the means for defining moderate to high resolution structures and the basic principles that have emerged from these studies. Among the topics covered are Hybrid Vigor, Structural Folds of Viral Proteins, Virus Particle Dynamics, Viral Gemone Organization, Enveloped Viruses and Large Viruses. Covers viral assembly using heterologous expression systems and cell extracts Discusses molecular mechanisms in bacteriophage T7 procapsid assembly, maturation and DNA containment Includes information on structural studies on antibody/virus complexes

Download or read book Virology E Book written by Stephen N J Korsman and published by Elsevier Health Sciences. This book was released on 2012-08-17 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise, highly accessible introduction to medical virology, incorporating essential basic principles as well as a systematic review of viruses and viral diseases. It pays particular attention to developments in anti-viral therapy that are becoming increasingly effective in modern medicine. It is an ideal textbook for the information-overloaded student and an invaluable everyday companion for the busy professional who needs a good understanding of the current state of medical virology. In keeping with the highly successful format of other Illustrated Colour Texts, it presents the subject as a series of succinct 2 page ‘learning units’, using a superb collection of clear illustrations and clinical photographs, concise yet comprehensive text and key point boxes to aid quick access to information and examination preparation. So whether you are a medical student, junior doctor, medical scientist, trainee in infectious diseases or student on another allied medical course, this book is here to make your life easier! It will also provide a very solid foundation for any who plan to delve deeper into this fascinating field. Part of the popular Illustrated Colour Text series Information presented in double page spreads for easy learning Highly illustrated with both full colour graphics and clinical photographs Each spread includes a key point box for exam preparation

Download or read book Viruses of Lower Vertebrates written by Winfried Ahne and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: Attention to viral infections and pathology previously focussed on diseases of economically important fish. In recent years, however, much new information on molecular virology and oncogenicity derives from viruses occurring in amphibians. New insights into the field of zoonosis were gained by studies of lower vertebrates serving as intermediate hosts in multiple human infections. Certain viruses, e.g. the influenza virus or calicivirus, seem capable of bridging species lines and even the land - sea interface. Global developments in aquaculture are indicated in influenza pandemics. These proceedings present research findings on viruses of fish, amphibians and reptiles, including defence mechanisms, zoonoses, evolutionary considerations and diagnostic approaches.