Download or read book Ectasia Patients and Strengthening the Cornea by Collagen Cross linkage written by Kristina Rhodes and published by . This book was released on 2010 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: This synopsis is intended to provide the reader with information about corneal ectasia and corneal collagen cross-linking. Corneal ectasia is a bulging and stretching of the cornea that causes unstable blurry vision. Ectasia can take on many different forms and presentations in the cornea of patients. Different types of ectasia include: Keratoconus, pellucid marginal degeneration, and post refractive surgery induced ectasia. Hard contact lenses are the current treatment for mild to moderate cases of corneal ectasia; however in advanced ectasia more invasive treatment options include intrastromal implants and corneal transplant. Corneal cross linking combines riboflavin and UVA light treatment in a procedure to stiffen the cornea while increasing the strength and decreasing the refractive correction of the eye. Internationally this treatment has shown positive results in the regression of ectasia. Corneal collagen cross-linking is currently undergoing trials in the United States. Corneal cross linking procedure may offer a fast and safe alternative for patients with ectasia not correctable by conventional means of treatment.

Download or read book Corneal Collagen Cross Linking written by Mazen M. Sinjab and published by Springer. This book was released on 2016-11-09 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive coverage of corneal collagen cross-linking (CXL), a major management modality for keratoconus and ectatic corneal disorders. All aspects are covered, including refractive and non-refractive surgery indications, models of application, safety, efficacy, performance, outcome measures, evidence of CXL, complications, contraindications, use in children, and controversies. The discussion reflects the considerable progress that has been made in understanding of the modality since its development in the late 1990s. Detailed attention is paid to new concepts, changing surgical techniques and indications, the latest evidence-based science and research, and the future of CXL. Guidance is also provided on the use of CXL in combination with other modalities, such as LASIK, PRK, intracorneal ring implantation and others. The text is accompanied by numerous high-quality color illustrations. Corneal Collagen Cross Linking will provide the reader with a sound grasp of the technique and its use and will hopefully also serve as a stimulus to further research and advances.

Download or read book Management of Early Progressive Corneal Ectasia written by Cosimo Mazzotta and published by Springer. This book was released on 2017-11-08 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a rapid overview of crosslinking protocols and the therapeutic guidelines to optimize the application according to patients age and ectasia staging. This book is unique in the field of crosslinking therapy, as it gives the readers a complete guide for their daily practice to understand the modern accelerated crosslinking protocols, indications and customized treatment strategies. Ophthalmic specialists, opticians, optometrists and doctors working in ophthalmic settings, will find this book to be a ‘go-to’ guide for furthering clinical knowledge of this specialized treatment for early progressive corneal ectasia.

Download or read book Corneal Biomechanics written by C.J. Roberts and published by Kugler Publications. This book was released on 2017-05-15 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: While lecturing in recent months at a number of prominent institutions, I asked some of the residents and fellows whether and how they might benefit from a book on corneal biomechanics. The typical response was the look of a deer caught in the headlights as they tried to intuit the “appropriate” answer, but had little understanding or insight as to why this would be an important and useful knowledge base for them now, or in the future. I then posed the question differently. “Would a book that explained corneal biomechanical principles and testing devices and their application in detecting eyes at risk for developing keratoconus and post-LASIK ectasia, understanding the biomechanical impact of specific types of keratorefractive surgery and riboflavin UV-A corneal collagen cross-linking, and the impact of corneal biomechanics on the fidelity of intraocular pressure measurement and risk for glaucoma progression be of interest?” Framed in this context, the answer I got was a resounding, “Yes!” Therein lies a fundamental disconnect that highlights both the opportunity and need to educate all ophthalmologists about this nascent field. This comprehensive book is strengthened by the breadth of contributions from leading experts around the world and provides an important resource for ophthalmologists at all levels of training and experience. It gives a panoramic snapshot of our understanding of corneal biomechanics today, bridging the gap between theoretical principles, testing devices that are commercially available and in development as well as current and potential future clinical applications. While there has been a long-held appreciation that all types of keratorefractive surgery have an impact and interdependence on corneal biomechanics and wound healing, the initial finite element analyses that were applied to understand radial keratotomy were limited by incorrect assumptions that the cornea was a linear, elastic, homogenous, isotropic material.1 With the advent of excimer laser vision correction, critical observations indicated that Munnerlyn’s theoretic ablation profiles did not account for either lower or higher order (e.g. spherical aberration) refractive outcomes,2 suggesting that there were important components missing from the equation—e.g., corneal biomechanics and wound healing. In a seminal editorial, Roberts3 pointed out that the cornea is not a piece of plastic, but rather a material with viscoelastic qualities. Since that time, much has been learned about spatial and depth- related patterns of collagen orientation and interweaving, as well as the biomechanical response to different keratorefractive surgeries that sever tension-bearing lamellae, as the cornea responds to and redistributes stress induced by IOP, hydration, eye rubbing, blinking and extraocular muscle forces.3-6 The first reports of post-LASIK ectasia7 highlighted the need to identify a biomechanical signature of early keratoconus as well as corneas at high risk of developing ectasia irrespective of their current topography or tomography. The introduction of two instruments into clinical use—the Ocular Response Analyzer (ORA) and the Corneal Visualization Scheimpflug Technology (Corvis ST)—that allow measurement of various biomechanical metrics further catapulted the field. The availability of these instruments in routine clinical settings allowed the systematic study of the effect of age, collagen disorders, collagen cross-linking, corneal rings, flaps of various depths, contour, sidecut angulation, pockets, and flockets, just to name of few. Future application of biomechanics to the sclera may improve our understanding of the development and prevention of myopia, as well as scleral surgeries and treatments under development for presbyopia. It was appreciated by Goldmann and Schmidt that corneal thickness and curvature would influence the measurement of applanation tonometry. The recent ability to measure some corneal biomechanical metrics have led to IOP measurement that may be more immune both to their influence and the impact of central corneal thickness (CCT). Certain chapters in this book explain how a thin cornea could be stiffer than a thick one and that stiffness is also impacted by IOP, thereby precluding simplistic attempts to adjust IOP measurements using nomograms based upon CCT alone. Also highlighted is how corneal hysteresis, the ability of the cornea to absorb and dissipate energy during the bidirectional applanation response to a linear Gaussian air puff, appears to be an independent risk factor for glaucoma progression and rate of progression.9,10 This comprehensive book starts out with a section devoted to outlining basic biomechanical principles and theories, teaching us the language of what Dupps11 has referred to as “mechanospeak”, thus providing a context and common vocabulary to better comprehend the following chapters. By first defining basic concepts such as stress-strain relationships and creep, this theoretical basis is later applied to explain the pathogenesis of corneal diseases, e.g., explaining how a focal abnormality in corneal biomechanical properties precipitates a cycle of decompensation and localized thinning and steepening, clinically expressed as ectasia progression. These early chapters further detail biomechanical differences between in-vivo and ex-vivo testing, between human and animal corneas and sclera, and between methods of testing. The second section provides a thorough description of two FDA-approved devices to measure corneal biomechanics in the clinic (i.e., the ORA and the Corvis ST), as well as an overview of potential future technologies, including OCT with air puff stimulus, ocular pulse elastography, and Brilloiun microscopy. The third and final section of the book is a thorough treatise on how to interpret the metrics derived from the waveform provided by available clinical devices; their adjunct use in ectasia risk screening; the comparative biomechanical impact of various keratorefractive surgeries and corneal procedures such as PRK, LASIK, SMILE, and corneal collagen cross-linking; the impact of corneal biomechanics on IOP measurement; and potential biomechanical markers of enhanced susceptibility to glaucoma progression. This compendium of our current knowledge of corneal biomechanics, its measurement and application, provides a strong foundation to more fully understand advances in keratorefractive and corneal surgery, diseases, and treatments, all of which are interdependent on and influence inherent corneal biomechanical properties and behavior. Both the robust aspects and limitations of our current understanding are presented, including the challenge of creating accurate and predictive finite element models that incorporate the impact of IOP, corneal thickness, geometry, and scleral properties on corneal biomechanics. This book provides a key allowing clinical ophthalmologists and researchers to grasp the basics and nuances of this exciting field and to shape it as it evolves in the future.

Download or read book Corneal Cross Linking written by Farhad Hafezi and published by CRC Press. This book was released on 2024-06-01 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Corneal Cross-Linking, Second Edition represents an innovative approach to treating primary acquired and secondary induced ectatic disorders. In addition, corneal cross-linking (CXL) has promising applications as an alternative in the treatment of corneal infectious and non-infectious melting, as well as conditions such as Fuchs’ endothelial dystrophy. The new and expanded Second Edition of Corneal Cross-Linking by Drs. Farhad Hafezi and J. Bradley Randleman will provide a concise yet comprehensive summary of the CXL process, including the basic science foundations, treatment protocols and outcomes, recognition and management of potential complications, and modification of standard protocol for special circumstances. Given all the changes in this rapidly progressing field, many brief topics from the first edition have now grown into full chapters or sections. These include expanded sections on alternative treatment protocols, corneal imaging and biomechanics, combing cross-linking with other refractive treatments, and a section devoted specifically to the most highly debated controversies in the field today. With each chapter being fully updated plus including over twenty new chapters that covers the latest advances and future directions, Corneal Cross-Linking, Second Edition represents the cutting-edge of CXL research and clinical practice. “Since the publication of the first edition of this book in 2013, our knowledge of corneal cross-linking has again significantly increased, both scientifically and clinically. Today, concise recommendations (guidelines for cross-linking) help the clinician to select the patients, make decisions, and provide optimal treatment” -Eberhard Spoerl, PhD and Theo Seiler, MD, PhD

Download or read book Treatment of Keratoconus written by Rebecca Murati and published by . This book was released on 2015 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: Corneal ectasia refers to an unstable cornea secondary to progressive thinning leading visual distortions and fluctuations. Corneal collagen cross-linking with riboflavin/ultraviolet A is a developing non-invasive treatment that has proven to delay keratoconus progression; it is currently being used in Europe & Canada, and is in the process of FDA approval in the USA. Even though corneal cross-linking has been mainly used for management of progressive keratoconus it is also an efficient treatment for pellucid marginal corneal degeneration, and keratectasia after refractive surgery. The treatment has shown improvement in vision, keratometric, and topographic parameters. This project reviewed published literature on corneal cross-linking to analyze and compare whether the transepithelial technique is safer and more effective than the epithelium-off method for keratoconus patients. After analyzing published studies, this review would recommend patients to undergo the transepithelial corneal cross-linking procedure because of its efficiency aiding corneal ectasias, and superior patient comfort with less complications; but there is an evident need for further studies comparing epithelium "off", transepithelial, and the combined epithelium "off" and transepithelial corneal cross-linking for a definite conclusion.

Download or read book Corneal Cross Linking written by Lawrence M Hopp and published by Addicus Books. This book was released on 2018-07-01 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: Have you been diagnosed with corneal disease? If so, you undoubtedly have questions. How will your eyesight be affected? How can your condition be treated? What are the potential complications of treatment? Dr. Lawrence M. Hopp, M.D., M.S. is a cornea specialist, fellowship-trained in refractive surgery, who has treated thousands of patients with diseases of the cornea. He understands your concerns and offers information that will help ease your anxiety. In Corneal Cross-Linking: Treatment for Cornea Disease, he discusses how cornea diseases develop and how they are best treated. He covers such topics as: signs and symptoms of corneal diseases; corneal disease diagnosis; newest treatments, such as collagen linking, cornea transplants and when they are needed, potential complications of treatment, and more.

Download or read book Corneal Collagen Cross linking and Its Many Benefits written by Craig Jensen and published by . This book was released on 2014 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: Corneal collagen cross-linking has been around for thousands of year. Only recently has it been studied more in depth as a way to control keratoconus. Up until recently, this has been the only treatment considered in collagen cross-linking. However, more recent studies have found many alternative treatment options for corneal collagen cross-linking. Currently, studies into benefits of collagen cross-linking range from treating thin corneas, and those with other form of ectasia, to treating edematous or bullous corneas. Studies for treatment options have also branched into ways of treating infectious keratitis, to even utilizing collagen cross-linking as a means of controlling low amounts of ametropia, as a stand-alone treatment, or used in conjunction with other refractive corneal surgeries. Currently, Collagen cross-linking is a standard of care in many international countries, however, in the United States, it has yet to pass through national acceptance and approval. The benefits of collagen cross-linking as a treatment option for a broad array of corneal conditions are becoming increasingly obvious.

Download or read book Controversies in the Management of Keratoconus written by Adel Barbara and published by Springer. This book was released on 2019-02-04 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents new technologies which are available now for the rehabilitation of visual acuity in patients suffering from keratoconusand for arresting the progression of this frustrating disease. All these current treatment options in differing combinations aim to improve the quality of life of the patients and although successful, they are causing confusion for the ophthalmologists; what procedure to do and when? How to perform? Which combination of treatments to choose? Controversies in the Management of Keratoconusprovidesthe widely used treatment options for keratoconus including collagen corneal cross –linking (CXL) covering all the available techniques, intrastromal corneal ring segments (ICRS) , phakic intra-ocular lenses (IOLs), photorefractive keratectomy (PRK) combined or not with CXL penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty ( DALK). Each treatment is addressed by more than one author with different points of view in order to present the various approaches, the logic behind them and the most relevant clinical data available.A chapter by the editor tries to put some light on how to navigate among these controversies. This book will be of interest to trainees as well as the specialized ophthalmologists.

Download or read book Ocular Imaging written by George Asimellis and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Femtosecond Laser Assisted Keratoplasty written by Jorge L Alio and published by JP Medical Ltd. This book was released on 2013-07-30 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keratoplasty is the transplantation of all or part of the cornea to repair scarred or damaged tissue. A femtosecond laser is a laser which emits ultrashort pulses, used for minimally invasive corneal surgery. This book is a concise guide to the technique of femtosecond laser-assisted keratoplasty. Beginning with an introduction to the technology, the following chapters discuss its use for different disorders. This practical text is based on the surgical experience of its internationally recognised authors from Spain, Germany, France and the USA. It includes more than 230 full colour clinical photographs and illustrations to enhance learning. Key points Concise guide to the corneal transplantation procedure of femtosecond laser-assisted keratoplasty Covers key technologies and uses for different disorders Internationally recognised author and editor team Includes more than 230 clinical photographs and illustrations

Download or read book Mastery of Holcomb C3 R Crosslinking for Keratoconus Other Disorders For Patients and Physicians written by Brian S Boxer Wachler and published by JP Medical Ltd. This book was released on 2013-03-31 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keratoconus is degeneration of the structure of the cornea. The cornea is the clear tissue covering the front of the eye. In keratoconus, the shape of the cornea slowly changes from round to conical (PubMed Health). In the early stages, keratoconus can be corrected with the use of lenses, but in the later stages, surgery is the only option. Holcomb C3-R® is a non-surgical technique that involves placing drops of the vitamin Riboflavin into the eye and using a UV light to activate them. The drops strengthen the fibres of the cornea and over time, preserve sight (American Keratoconus Association). This book is a concise guide to the technique of Holcomb C3-R® to treat keratoconus. Authored by the inventor of the procedure, Brian S Boxer Wachler, the text is based on his first hand clinical experience and explains the history and basic science of cross linking, the development and naming of the technique, its uses and complications, and first patient results. Key points Concise guide to technique of Holcomb C3-R® to treat keratoconus Authored by inventor of the technique and based on clinical experience Includes more than 60 full colour images and illustrations

Download or read book Management of Complications in Refractive Surgery written by Jorge L. Alio and published by Springer. This book was released on 2018-01-02 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This illustrated guide is written by international opinion leaders with extensive experience in the practice of refractive surgery. It is the first book devoted to refractive complications (with practical hints and case reports on outcomes) to provide ophthalmic surgeons with the most adequate solutions for the most frequent problems. All complications are described and lavishly illustrated. The book provides ophthalmic surgeons with the most adequate solutions for the most frequent problems they face in their daily practice.

Download or read book Astigmatism written by Michael Goggin and published by BoD – Books on Demand. This book was released on 2012-02-29 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the development, optics and physiology of astigmatism and places this knowledge in the context of modern management of this aspect of refractive error. It is written by, and aimed at, the astigmatism practitioner to assist in understanding astigmatism and its amelioration by optical and surgical techniques. It also addresses the integration of astigmatism management into the surgical approach to cataract and corneal disease including corneal transplantation.

Download or read book Refractive Surface Ablation written by Paolo Vinciguerra and published by SLACK Incorporated. This book was released on 2007 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: With surface treatments gaining in popularity, a book that addresses in-depth analysis of the latest advancements is essential. This title offers step-by-step information on everything from the patient selection process to performing the procedures to patient management.

Download or read book Contact Lens Practice E Book written by Nathan Efron and published by Elsevier Health Sciences. This book was released on 2016-11-27 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this thoroughly revised and updated third edition of Contact Lens Practice, award-winning author, researcher and lecturer, Professor Nathan Efron, provides a comprehensive, evidence-based overview of the scientific foundation and clinical applications of contact lens fitting. The text has been refreshed by the inclusion of ten new authors – a mixture of scientists and clinicians, all of whom are at the cutting edge of their specialty. The chapters are highly illustrated in full colour and subject matter is presented in a clear and logical format to allow the reader to quickly hone in the desired information. Ideal for an optometrist, ophthalmologist, orthoptist, optician, student, or work in the industry, this book will serve as an essential companion and guide to current thinking and practice in the contact lens field. Highlights of this edition include a new chapter on myopia control contact lenses, as well are completely rewritten chapters, by new authors, on keratoconus, orthokeratology, soft and rigid lens measurement and history taking.

Download or read book Corneal Cross linking with Riboflavin for Keratoconus written by Canadian Agency for Drugs and Technologies in Health and published by . This book was released on 2013 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keratoconus (KC) is a degenerative disorder of the eye in which cornea becomes progressively thinner and bows outward into a more conical shape than its normal gradual curve. KC affects approximately 0.05% of the global population. Patients with KC often experience eye irritation, headaches, light halos, light sensitivity, worsening myopia, and impaired quality of life. KC is usually diagnosed in the adolescent period. Various treatment options for KC include simple correction with glasses, soft or rigid gas permeable contact lenses, surgical implantation of intrastromal corneal ring segments (Intacs), and corneal transplant. In addition, corneal-crosslinking with riboflavin and ultraviolet A (CXL) is increasingly considered as a method for managing KC. The treatment objective for CXL is to stabilize the underlying disease process by strengthening the stromal collagen network in order to delay or defer the need for corneal transplant. In the process of CXL, riboflavin (vitamin B2) works as a photo-mediator to increase the absorption of ultraviolet A light into the corneal stroma. The ultraviolet A (UVA: 370 nm) light increases the degree of molecular bonds of the extracellular matrix of the cornea. Therefore, CXL slows or even stops the progression of KC by increasing the strength and rigidity of the cornea. CXL can be performed with or without removing corneal epithelium. Common reported side-effects of CXL are blurry vision, lacrimation and the sensation of a foreign body for approximately 24 to 48 hours. Serious side effects include corneal haze and keratitis. CXL is only indicated for patients with corneas greater than 400 mcm thick. Corneal cross-linking with riboflavin -- UVA for keratoconus has been increasingly used in some Canadian jurisdictions. However it is currently not covered by any Canadian jurisdiction. Demand for CXL as the standard of care for keratoconus is increasing in some Canadian jurisdictions, although the long-term effectiveness and CXL's impact on the need for corneal transplant is unknown. The objective of this report is to review the clinical effectiveness (such as improved vision and corneal strength/stabilization) and cost-effectiveness on CXL in the treatment of keratoconus.