Download or read book Ebola s Evolution written by Michael B. A. Oldstone and published by Archway Publishing. This book was released on 2021-06-04 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an intimate portrait of multiple outbreaks of Ebola in Africa and reveals how the results of that experience can help us fight COVID-19. Michael B.A. Oldstone, who led the Viral-Immunobiology Laboratory at the Scripps Research Institute worked with Ebola, teams up with Madeleine Rose Oldstone to give a detailed account of the 2013-2016 and 2018-2020 Ebola outbreaks. The authors trace the origin of the disease, its spread like a tsunami thru Guinea, Sierra Leone and Liberia, the collapse of economies, and the development of anti-viral therapies against Ebola. They compare the outbreaks of one of the world’s deadliest viruses with today’s struggle to overcome the COVID-19 pandemic. You will gain intimate knowledge of a deadly pathogen that devastated a region of the world that lacks resources to fight it, and learn why the world was unprepared for the Ebola outbreak. You will meet people who fought heroically with limited resources, including Sheik Kahn who died fighting Ebola and was declared a national hero by the Sierra Leone government, Pardis Sabeti, a geneticist working in infectious diseases from Harvard and MIT who was named “Scientist of the Year” by Time magazine, and Robert Garry, who headed the fight against viral hemorrhagic diseases and kept the White House and the press informed. Sabeti and Garry worked with Oldstone and provided information about the outbreak to the authors, making the narrative particularly incisive and timely. Ebola’s Evolution will give you a fast paced, detailed, and fascinating picture of a feared disease that killed thousands of people and threatening to become a global pandemic before it was stopped.
Download or read book Ebola written by David Quammen and published by Random House. This book was released on 2014-10-02 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1976 a deadly virus emerged from the Congo forest. As swiftly as it came, it disappeared, leaving no trace. Over the four decades since, Ebola has emerged sporadically, each time to devastating effect. It can kill up to 90% of its victims. In between these outbreaks, it is untraceable, hiding deep in the jungle. The search is on to find Ebola’s elusive host animal. And until we find it, Ebola will continue to strike. Acclaimed science writer and explorer David Quammen first came near the virus whilst travelling in the jungles of Gabon, accompanied by local men whose village had been devastated by a recent outbreak. Here he tells the story of Ebola, its past, present and its unknowable future.
Download or read book Ebola An Evolving Story written by James Lyons-weiler and published by World Scientific. This book was released on 2015-05-27 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selected as CHOICE magazine's Outstanding Academic Title, January 2017.The book is a narrative of the unfolding of the Ebola virus disease outbreak from a scientific view point. The author provides an analysis of the scientific basis of public health policies that have influenced the public's, and the medical community's, abilities to understand the virus and the disease. This is done in the context of providing insights into the biology of the virus, and exploring open questions, including its likely modes of transmission. The author has included citations from the scientific literature and the press, as well as quotes from expert interviews. The book will help sort out the fact from fiction, given the confusion that arose after the virus arrived in the US. The author used his objective research skills and knowledge of evolutionary genetics and molecular biology to find out what was known, and what questions remained unanswered, and even what questions remained unasked.Written in an accessible style, it is intended for the educated general public, scientists, policy makers, health care workers, and politicians. It delves into the problems of trying to derive a logic-based understanding of a highly lethal emerging disease in 2014, when research funding cuts have gutted research institutions, and when public health institutions really were woefully unprepared. It is a highly distinct narrative analysis that is sure to stimulate new research and thinking in public policy. It will inform thousands of people of the nature of the virus, how it works, in terms they are likely to be able to understand. It will allow others to rapidly catch up with the story of Ebola.
Download or read book Ebola and Marburg Viruses written by Hans-Dieter Klenk and published by Garland Science. This book was released on 2004 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Ebola and Marburg viruses are a pair of filoviruses that are among the most lethal hemorrhagic viruses on the planet. The authors present a review of past and current research into these pathogens, including 12 papers addressing the structure of the viral proteins; genomic replication; molecular mechanisms of entry; pathogenesis in nonhuman primates, guinea pigs, and mice; virus modulation of innate immunity; and cellular and molecular mechanisms of Ebola pathogenicity and related approaches to vaccine development.
Download or read book Fevers Feuds and Diamonds written by Paul Farmer and published by Macmillan + ORM. This book was released on 2020-11-17 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Paul Farmer brings his considerable intellect, empathy, and expertise to bear in this powerful and deeply researched account of the Ebola outbreak that struck West Africa in 2014. It is hard to imagine a more timely or important book.” —Bill and Melinda Gates "[The] history is as powerfully conveyed as it is tragic . . . Illuminating . . . Invaluable." —Steven Johnson, The New York Times Book Review In 2014, Sierra Leone, Liberia, and Guinea suffered the worst epidemic of Ebola in history. The brutal virus spread rapidly through a clinical desert where basic health-care facilities were few and far between. Causing severe loss of life and economic disruption, the Ebola crisis was a major tragedy of modern medicine. But why did it happen, and what can we learn from it? Paul Farmer, the internationally renowned doctor and anthropologist, experienced the Ebola outbreak firsthand—Partners in Health, the organization he founded, was among the international responders. In Fevers, Feuds, and Diamonds, he offers the first substantive account of this frightening, fast-moving episode and its implications. In vibrant prose, Farmer tells the harrowing stories of Ebola victims while showing why the medical response was slow and insufficient. Rebutting misleading claims about the origins of Ebola and why it spread so rapidly, he traces West Africa’s chronic health failures back to centuries of exploitation and injustice. Under formal colonial rule, disease containment was a priority but care was not – and the region’s health care woes worsened, with devastating consequences that Farmer traces up to the present. This thorough and hopeful narrative is a definitive work of reportage, history, and advocacy, and a crucial intervention in public-health discussions around the world.
Download or read book The Ebola Epidemic in West Africa written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-12-30 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most recent Ebola epidemic that began in late 2013 alerted the entire world to the gaps in infectious disease emergency preparedness and response. The regional outbreak that progressed to a significant public health emergency of international concern (PHEIC) in a matter of months killed 11,310 and infected more than 28,616. While this outbreak bears some unique distinctions to past outbreaks, many characteristics remain the same and contributed to tragic loss of human life and unnecessary expenditure of capital: insufficient knowledge of the disease, its reservoirs, and its transmission; delayed prevention efforts and treatment; poor control of the disease in hospital settings; and inadequate community and international responses. Recognizing the opportunity to learn from the countless lessons of this epidemic, the National Academies of Sciences, Engineering, and Medicine convened a workshop in March 2015 to discuss the challenges to successful outbreak responses at the scientific, clinical, and global health levels. Workshop participants explored the epidemic from multiple perspectives, identified important questions about Ebola that remained unanswered, and sought to apply this understanding to the broad challenges posed by Ebola and other emerging pathogens, to prevent the international community from being taken by surprise once again in the face of these threats. This publication summarizes the presentations and discussions from the workshop.
Download or read book The Hot Zone written by Richard Preston and published by Anchor. This book was released on 2012-03-14 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bestselling landmark account of the first emergence of the Ebola virus. Now a mini-series drama starring Julianna Margulies, Topher Grace, Liam Cunningham, James D'Arcy, and Noah Emmerich on National Geographic. A highly infectious, deadly virus from the central African rain forest suddenly appears in the suburbs of Washington, D.C. There is no cure. In a few days 90 percent of its victims are dead. A secret military SWAT team of soldiers and scientists is mobilized to stop the outbreak of this exotic "hot" virus. The Hot Zone tells this dramatic story, giving a hair-raising account of the appearance of rare and lethal viruses and their "crashes" into the human race. Shocking, frightening, and impossible to ignore, The Hot Zone proves that truth really is scarier than fiction.
Download or read book Ebola the History of the Virus and Its Outbreaks written by Charles River Editors and published by Createspace Independent Publishing Platform. This book was released on 2017-10-16 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: *Includes pictures *Includes accounts written by doctors, scientists, and survivors about the history and effects of the virus *Includes a bibliography for further reading "The Ebola epidemic ravaging parts of West Africa is the most severe acute public health emergency seen in modern times. Never before in recorded history has a biosafety level four pathogen infected so many people so quickly, over such a broad geographical area, for so long." - World Health Organization, September 2014 It has long been a maxim that it is easy to forget when one is at war who the enemy really is, and that can certainly be said for the Ebola virus, which recently catapulted into headlines and instantly became the most feared disease in the world. In the case of the fight against Ebola, the enemy is not the person who has contracted the disease, nor is it the region where the virus has flourished. The enemy is a microscopic virus that, when seen under sufficient magnification, looks like a piece of loosely knotted rope. While a picture of Ebola under a microscope might look innocuous, it is a living organism that can be killed, but if it is not, it will multiply and evolve much like any other organism, including the human beings it so often kills. Despite the fact Ebola has been notorious for nearly 40 years, its ability to hide and change with the times has made its origins murky and left scientists without a vaccine. The World Health Organization (WHO) was able to identify the previously unknown disease after an outbreak in Sudan that killed a majority of the infected victims in 1976, and a doctor graphically described its effects later that year: "The illness is characterized with a high temperature of about 39�C [102�F], hematemesis, diarrhea with blood, retrosternal abdominal pain, prostration with 'heavy' articulations, and rapid evolution death after a mean of three days." Ultimately named after the Ebola River, the virus was a strain of the Marburg virus, and when it struck various nations in Africa from 1976-2003, it had incredibly high mortality rates and left hundreds dead in places like Zaire, Uganda, and the Democratic Republic of Congo. Most recently, a massive outbreak of Ebola began in Guinea and hit Liberia, where it has left thousands dead and ravaged local economies. All the while, the WHO conceded, "Countries affected to date simply do not have the capacity to manage an outbreak of this size and complexity on their own. I urge the international community to provide this support on the most urgent basis possible." In the meantime, the disease has trickled out to other nations, including the United States, and as of October 2014, there has been a scramble to isolate potential victims and race towards developing a vaccine. Ebola: The History of the Disease and Its Outbreaks looks at the origins of the disease and explains its causes, symptoms, and effects while discussing the current outbreak and previous ones. Along with pictures and a bibliography, you will learn about the Ebola virus like never before, in no time at all.
Download or read book The Evolution and Emergence of RNA Viruses written by Edward C. Holmes and published by Oxford University Press. This book was released on 2009-06-25 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: While the study of viral evolution has developed rapidly in the last 30 years, little attention has been directed toward linking the mechanisms of viral evolution to the epidemiological outcomes of these processes. This book intends to fill this gap by considering the patterns and processes of viral evolution at all its spatial and temporal scales.
Download or read book Global Health Risk Framework written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-05-06 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the 2014 Ebola outbreak many public- and private-sector leaders have seen a need for improved management of global public health emergencies. The effects of the Ebola epidemic go well beyond the three hardest-hit countries and beyond the health sector. Education, child protection, commerce, transportation, and human rights have all suffered. The consequences and lethality of Ebola have increased interest in coordinated global response to infectious threats, many of which could disrupt global health and commerce far more than the recent outbreak. In order to explore the potential for improving international management and response to outbreaks the National Academy of Medicine agreed to manage an international, independent, evidence-based, authoritative, multistakeholder expert commission. As part of this effort, the Institute of Medicine convened four workshops in summer of 2015 to inform the commission report. The presentations and discussions from the Workshop on Research and Development of Medical Products are summarized in this report.
Download or read book Ebola The Natural and Human History of a Deadly Virus written by David Quammen and published by W. W. Norton & Company. This book was released on 2014-10-20 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: “A frightening and fascinating masterpiece of science reporting that reads like a detective story.” —Walter Isaacson In 1976 a deadly virus emerged from the Congo forest. As swiftly as it came, it disappeared, leaving no trace. Over the four decades since, Ebola has emerged sporadically, each time to devastating effect. It can kill up to 90 percent of its victims. In between these outbreaks, it is untraceable, hiding deep in the jungle. The search is on to find Ebola’s elusive host animal. And until we find it, Ebola will continue to strike. Acclaimed science writer and explorer David Quammen first came near the virus while he was traveling in the jungles of Gabon, accompanied by local men whose village had been devastated by a recent outbreak. Here he tells the story of Ebola—its past, present, and its unknowable future. Extracted from Spillover by David Quammen, updated and with additional material.
Download or read book Ebola s Evolution written by Michael B a Oldstone and published by Archway Publishing. This book was released on 2021-06-04 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an intimate portrait of multiple outbreaks of Ebola in Africa and reveals how the results of that experience can help us fight COVID-19. Michael B.A. Oldstone, who led the Viral-Immunobiology Laboratory at the Scripps Research Institute worked with Ebola, teams up with Madeleine Rose Oldstone to give a detailed account of the 2013-2016 and 2018-2020 Ebola outbreaks. The authors trace the origin of the disease, its spread like a tsunami thru Guinea, Sierra Leone and Liberia, the collapse of economies, and the development of anti-viral therapies against Ebola. They compare the outbreaks of one of the world's deadliest viruses with today's struggle to overcome the COVID-19 pandemic. You will gain intimate knowledge of a deadly pathogen that devastated a region of the world that lacks resources to fight it, and learn why the world was unprepared for the Ebola outbreak. You will meet people who fought heroically with limited resources, including Sheik Kahn who died fighting Ebola and was declared a national hero by the Sierra Leone government, Pardis Sabeti, a geneticist working in infectious diseases from Harvard and MIT who was named "Scientist of the Year" by Time magazine, and Robert Garry, who headed the fight against viral hemorrhagic diseases and kept the White House and the press informed. Sabeti and Garry worked with Oldstone and provided information about the outbreak to the authors, making the narrative particularly incisive and timely. Ebola's Evolution will give you a fast paced, detailed, and fascinating picture of a feared disease that killed thousands of people and threatening to become a global pandemic before it was stopped.
Download or read book Ebola written by Paul Richards and published by Zed Books Ltd.. This book was released on 2016-09-15 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shortlisted for the Fage and Oliver Prize 2018 From December 2013, the largest Ebola outbreak in history swept across West Africa, claiming thousands of lives in Liberia, Sierra Leone and Guinea. By the middle of 2014, the international community was gripped by hysteria. Experts grimly predicted that millions would be infected within months, and a huge international control effort was mounted to contain the virus. Yet paradoxically, by this point the disease was already going into decline in Africa itself. So why did outside observers get it so wrong? Paul Richards draws on his extensive first-hand experience in Sierra Leone to argue that the international community’s panicky response failed to take account of local expertise and common sense. Crucially, Richards shows that the humanitarian response to the disease was most effective in those areas where it supported these initiatives and that it hampered recovery when it ignored or disregarded local knowledge.
Download or read book The Evolution of Ebola written by Gwendolyn Olmsted and published by CreateSpace. This book was released on 2014-11-17 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: Initially not discovered until 1976 in Sudan, Africa, the Ebola virus was named after the Ebola River near where its first outbreak occurred. Belgian doctor Peter Piot, a 27-year-old scientist and medical school graduate training as a clinical microbiologist, was sent to the region nearly forty years ago to find out why people were dying of a mysterious illness. He uncovered the Ebola virus, yet averted his attention to the virus of the hour, AIDS upon return, so his research abruptly stopped on Ebola. Now Director of the London School of Hygiene and Tropical Medicine, he discusses the initial 1976 strain of Ebola and how it has evolved into the 2014 strain it is today. Virology, epidemiology and outbreaks, Reston and Marburg virus comparisons, research and vaccines, and current death count and outlook are also examined in this handy survival guide to the 2014 Ebola Virus Disease (EBOV) pandemic.
Download or read book Spillover Animal Infections and the Next Human Pandemic written by David Quammen and published by W. W. Norton & Company. This book was released on 2012-10 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: A masterpiece of science reporting that tracks the animal origins of emerginghuman diseases.
Download or read book Pandemic written by Sonia Shah and published by Macmillan. This book was released on 2016-02-16 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Interweaving history, original reportage, and personal narrative, Pandemic explores the origins of epidemics, drawing parallels between the story of cholera-- one of history's most disruptive and deadly pathogens-- and the new pathogens that stalk humankind today"--
Download or read book Framing Animals as Epidemic Villains written by Christos Lynteris and published by Springer Nature. This book was released on 2019-10-11 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes a historical and anthropological approach to understanding how non-human hosts and vectors of diseases are understood, at a time when emerging infectious diseases are one of the central concerns of global health. The volume critically examines the ways in which animals have come to be framed as ‘epidemic villains’ since the turn of the nineteenth century. Providing epistemological and social histories of non-human epidemic blame, as well as ethnographic perspectives on its recent manifestations, the essays explore this cornerstone of modern epidemiology and public health alongside its continuing importance in today’s world. Covering diverse regions, the book argues that framing animals as spreaders and reservoirs of infectious diseases – from plague to rabies to Ebola – is an integral aspect not only to scientific breakthroughs but also to the ideological and biopolitical apparatus of modern medicine. As the first book to consider the impact of the image of non-human disease hosts and vectors on medicine and public health, it offers a major contribution to our understanding of human-animal interaction under the shadow of global epidemic threat.
