Download or read book E Coli DNA Gyrase written by and published by . This book was released on 1989 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Action of DNA Gyrase at Rip Sites in E Coli written by Sheilagh Clarkson and published by . This book was released on 1998 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Isolation and Characterization of Escherichia Coli DNA Gyrase Mutations which Inhibit the Growth of Bacteriophage Mu written by Scott H. Shore and published by . This book was released on 1986 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Structure and Activities of Escherichia Coli DNA Gyrase written by and published by . This book was released on 1979 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Investigation of the Domain Structure of the Escherichia Coli DNA Gyrase A Protein written by Richard Jonathan Reece and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book E Coli D N A Gyrase written by Martin Edward Cullen and published by . This book was released on 1989 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book DNA Topology written by Andrew D. Bates and published by Oxford University Press, USA. This book was released on 2005 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A key aspect of DNA is its ability to form a variety of structures, this book explains the origins and importance of such structures"--Provided by publisher.

Download or read book Studies in Supercolling and DNA Gyrase in Escherichia Coli written by Robert James Franco and published by . This book was released on 1987 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biochemical and Genetic Studies of DNA Gyrase from Escherichia Coli and Staphylococcus Aureus written by and published by . This book was released on 1991 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Escherichia Coli DNA Gyrase Mutations that Conditionalyy Compensate for Loss of DNA Topoisormerase I Activity written by Craig S. Laufer and published by . This book was released on 1984 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Antimicrobial Resistance written by Donald L. Jungkind and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development and Implications of Antimicrobial Resistance One of the most ominous trends in the field of antimicrobial chemotherapy over the past decade has been the increasing pace of development of antimicrobial resistance among microbial pathogens. The hypothesis that man can discover a magic bullet to always cure a particular infection has proved false. Physicians are now seeing and treating patients for which there are few therapeutic alternatives, and in some cases, none at all. Until recently there was little concern that physicians might be losing the war in our ability to compete with the evolving resistance patterns of microbial pathogens. Now the general public is very aware of the threat to them if they become infected, thanks to cover story articles in major magazines such as Time, Newsweek, newspapers, and other news sources. Antimicrobial resistance is not a novel problem. Shortly after the widespread introduction of penicillin in the early 1940s, the first strains of penicillin-resistant staphylococci were described. Today it is an uncommon event for a clinical laboratory to isolate an S. aureus that is sensitive to penicillin. Other gram-positive strains of bacteria have become resistant, including the exquisitely sensitive Streptococcus pneumoniae. Sensitivity to vancomycin was once so uniform that it was used in routine clinical laboratories as a surrogate marker for whether an organism should be classified as a gram-positive. That criterion can no longer be relied upon because of emerging resistance among some species. Gram-negative bacteria, viruses, fungi, and parasites all have succeeded in developing resistance.

Download or read book New Method to Prepare E Coli Maxicells Using a DNA Gyrase Inhibitor written by Sujatha Ramakumar and published by . This book was released on 1993 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mechanistic Studies on DNA Gyrase from Escherichia Coli written by David Paul Weiner and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Quinolones written by Vincent T. Andriole and published by Elsevier. This book was released on 2000-10-09 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quinolones constitute a large class of synthetic antimicrobial agents that are highly effective in the treatment of many types of infectious diseases, particularly those caused by bacteria. New quinolones are continually being developed as bacterial species develop resistance to existing quinolones. This book presents the most current information available in our continual struggle to conquer disease. Over time, bacteria become resistant to medicines that are used to combat them. Because of this, the medical world is always in search of new and improved ways to battle these disease-causing bacteria. Quinolones are at the forefront of this research. Edited by one of the world's foremost authorities on the subject, the third edition of this highly successful title will serve as a valuable tool for primary care physicians and researchers interested in a comprehensive, up-to-date reference on the chemistry, mechanisms of action, development of resistance, and clinical efficacy of both currently available and newer quinolone compounds under investigation. This is the eagerly anticipated fully revised edition of the standard reference in the field. - Eagerly anticipated updated edition of noted title covering synthetic microbial agents that are useful against infectious disease, particularly those caused by bacteria - Edited by one of the foremost experts in the field of quinolone research and infectious disease - History of quinolones, chemistry & mechanisms of action, pharmacology, safety aspects - Role of quinolones in treating various types of infections, including respiratory infections, gastrointestinal infections, urinary tract infections, prostatitis, STDs and bacterial meningitis as well as their use in immunocompromised patients

Download or read book DNA Topoisomerase Protocols written by Mary-Ann Bjornsti and published by Springer Science & Business Media. This book was released on 1999-03-23 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Topoisomerase Protocols, I: DNA Topology and Enzymes brings together an unprecedented collection of cutting-edge experimental protocols for investigating DNA structure, topology, and DNA topoisomerase function. Described by expert experimentalists who have perfected the techniques, these unfailingly reproducible methods utilize new approaches to study changes in DNA topology (linking number, knotting, catenation, and relaxation) and DNA structure (bending), as well as to assess chromosome structure through FLP-mediated recombination and to analyze bacterial nucleoid structure. State-of-the-art protocols also detail the expression and purification of bacterial, viral, and eukaryotic DNA topoisomerases from a variety of sources, including baculovirus, and bacterial, yeast and mammalian expression systems. A companion volume, DNA Topoisomerase Protocols, v. 2: Enzymology and Drugs, provides detailed protocols to study the catalytic activities of DNA topoisomerases, as well as their specific interactions with topoisomerase-targeted antitumor and antibacterial drugs. DNA Topoisomerase Protocols, I: DNA Topology and Enzymes will be of immense value to the many basic scientists and clinicians who want better to understand and to exploit proficiently the wealth of recent discoveries about chromatin structure and its relation to gene expression, about DNA topoisomerases as the targets of antitumor and antibacterial agents, and about DNA repair.

Download or read book Studies on the Role of DNA Gyrase and DNA Supercoiling in Escherichia Coli Growth written by Todd Robert Steck and published by . This book was released on 1985 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies of DNA Gyrase Activity in Escherichia Coli and Salmonella Enterica Serovar Typhimurium written by Nikolay Rovinskiy and published by . This book was released on 2013 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gyrase introduces negative supercoils into bacterial DNA. In balance with topoisomerase I, it contributes to the maintenance of constant negative DNA supercoiling. It was shown that in Escherichia coli negative supercoil density of pBR322 plasmid is higher than in Salmonella typhimurium. One of the possible explanations of this phenomenon is a difference of DNA gyrase activity between E. coli and S. typhimurium. We developed in vitro assay of gyrase activity which has shown that DNA gyrases of E. coli and S. typhimurium have the same supercoiling end point, but E. coli gyrase works slightly faster than the S. typhimurium enzyme. To see how this rate difference influences supercoiling on the chromosome, the in vivo assay based on excision of sequence surrounded by resolvase sites has been used in various strains. The efficiency of resolvase action correlates with supercoiling density at the resolvase sites. This assay has shown that E. coli gyrB does not significantly influence supercoiling density, but E. coli gyrA relaxes the S. typhimurium chromosome. This fact can be explained by inefficient interaction of E. coli GyrA with S. typhimurium DNA.