Download or read book Alcohol Drugs and Impaired Driving written by A. Wayne Jones and published by CRC Press. This book was released on 2020-06-15 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol, Drugs, and Impaired Driving addresses many theoretical and practical issues related to the role played by alcohol and other psychoactive drugs on driving performance, road-traffic safety, and public health. Several key forensic issues are involved in the enforcement of laws regulating driving under the influence of alcohol and/or other drugs, including analytical toxicology, pharmacology of drug action, as well as the relationships between dose taken, concentration levels in the body, and impairment of performance and behavior. Our knowledge of drunken driving is much more comprehensive than drugged driving, so a large part of this book is devoted to alcohol impairment, as well as impairment caused by use of drugs other than alcohol. For convenience, the book is divided into four main sections. The first section gives some historical background about measuring alcohol in blood and breath as evidence for the prosecution of traffic offenders. The important role of the Breathalyzer instrument in traffic-law enforcement, especially in Australia, Canada, and the USA is presented along with a biographical sketch of its inventor (Professor Robert F. Borkenstein of Indiana University) with focus on the man, his work and his impact. The second section discusses several issues related to forensic blood and breath-alcohol alcohol analysis as evidence for prosecution of traffic offenders. This includes how the results should be interpreted in relation to impairment and an evaluation of common defense challenges. Because most countries have adopted concentration per se laws, the main thrust of the prosecution case is the suspect’s measured blood- or breath-alcohol concentration. This legal framework necessitates that the analytical methods used are "fit for purpose" and are subjected to rigorous quality assurance procedures. The third section gives a broad overview of the current state of knowledge about driving under the influence of non-alcohol drugs in various countries. This includes adoption of zero-tolerance laws, concentration per se statutes, and clinical evidence of driver impairment based on field sobriety tests and drug recognition expert evidence. The fourth section deals with epidemiology, enforcement, and countermeasures aimed at reducing the threat of drunken and drugged driving. All articles have appeared previously in the international journal Forensic Science Review, but all are completely updated with current data, references, and the latest research on developments since the articles were published. This book contains a convenient collection of the best articles covering recommendations for blood and breath testing methods, public policy relating to such methods, and forensic and legal implications of the enforcement of measures to counter driving under the influence.

Download or read book Evaluation of Enzyme Inhibitors in Drug Discovery written by Robert A. Copeland and published by John Wiley & Sons. This book was released on 2013-01-31 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers essential guidance for discovering and optimizing novel drug therapies Using detailed examples, Evaluation of Enzyme Inhibitors in Drug Discovery equips researchers with the tools needed to apply the science of enzymology and biochemistry to the discovery, optimization, and preclinical development of drugs that work by inhibiting specific enzyme targets. Readers will applaud this book for its clear and practical presentations, including its expert advice on best practices to follow and pitfalls to avoid. This Second Edition brings the book thoroughly up to date with the latest research findings and practices. Updates explore additional forms of enzyme inhibition and special treatments for enzymes that act on macromolecular substrates. Readers will also find new discussions detailing the development and application of the concept of drug-target residence time. Evaluation of Enzyme Inhibitors in Drug Discovery begins by explaining why enzymes are such important drug targets and then examines enzyme reaction mechanisms. The book covers: Reversible modes of inhibitor interactions with enzymes Assay considerations for compound library screening Lead optimization and structure-activity relationships for reversible inhibitors Slow binding and tight binding inhibitors Drug-target residence time Irreversible enzyme inactivators The book ends with a new chapter exploring the application of quantitative biochemical principles to the pharmacologic evaluation of drug candidates during lead optimization and preclinical development. The Second Edition of Evaluation of Enzyme Inhibitors in Drug Discovery continues to offer a treatment of enzymology applied to drug discovery that is quantitative and mathematically rigorous. At the same time, the clear and simple presentations demystify the complex science of enzymology, making the book accessible to many fields— from pharmacology to medicinal chemistry to biophysics to clinical medicine.

Download or read book Drug Identification and Testing in the Juvenile Justice System written by Ann H. Crowe and published by . This book was released on 1998 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Model Rules of Professional Conduct written by American Bar Association. House of Delegates and published by American Bar Association. This book was released on 2007 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Model Rules of Professional Conduct provides an up-to-date resource for information on legal ethics. Federal, state and local courts in all jurisdictions look to the Rules for guidance in solving lawyer malpractice cases, disciplinary actions, disqualification issues, sanctions questions and much more. In this volume, black-letter Rules of Professional Conduct are followed by numbered Comments that explain each Rule's purpose and provide suggestions for its practical application. The Rules will help you identify proper conduct in a variety of given situations, review those instances where discretionary action is possible, and define the nature of the relationship between you and your clients, colleagues and the courts.

Download or read book Evaluation of Enzyme Inhibitors in Drug Discovery written by Robert A. Copeland and published by John Wiley & Sons. This book was released on 2005-04-01 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vital information for discovering and optimizing new drugs "Understanding the data and the experimental details that support it has always been at the heart of good science and the assumption challenging process that leads from good science to drug discovery. This book helps medicinal chemists and pharmacologists to do exactly that in the realm of enzyme inhibitors." -Paul S. Anderson, PhD This publication provides readers with a thorough understanding of enzyme-inhibitor evaluation to assist them in their efforts to discover and optimize novel drug therapies. Key topics such as competitive, noncompetitive, and uncompetitive inhibition, slow binding, tight binding, and the use of Hill coefficients to study reaction stoichiometry are all presented. Examples of key concepts are presented with an emphasis on clinical relevance and practical applications. Targeted to medicinal chemists and pharmacologists, Evaluation of Enzyme Inhibitors in Drug Discovery focuses on the questions that they need to address: * What opportunities for inhibitor interactions with enzyme targets arise from consideration of the catalytic reaction mechanism? * How are inhibitors evaluated for potency, selectivity, and mode of action? * What are the advantages and disadvantages of specific inhibition modalities with respect to efficacy in vivo? * What information do medicinal chemists and pharmacologists need from their biochemistry and enzymology colleagues to effectively pursue lead optimization? Beginning with a discussion of the advantages of enzymes as targets for drug discovery, the publication then explores the reaction mechanisms of enzyme catalysis and the types of interactions that can occur between enzymes and inhibitory molecules that lend themselves to therapeutic use. Next are discussions of mechanistic issues that must be considered when designing enzyme assays for compound library screening and for lead optimization efforts. Finally, the publication delves into special forms of inhibition that are commonly encountered in drug discovery efforts, but can be easily overlooked or misinterpreted. This publication is designed to provide students with a solid foundation in enzymology and its role in drug discovery. Medicinal chemists and pharmacologists can refer to individual chapters as specific issues arise during the course of their ongoing drug discovery efforts.

Download or read book Drug Recognition Expert School written by and published by Jeffrey Frank Jones. This book was released on with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Ohio OVI Defense written by Timothy Huey and published by Lawyers & Judges Publishing Company Incorporated. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Athletic Horse written by David R. Hodgson and published by Elsevier Health Sciences. This book was released on 2013-06-07 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: - NEW full-color photographs depict external clinical signs, allowing more accurate clinical recognition. - NEW and improved imaging techniques maximize your ability to assess equine performance. - UPDATED drug information is presented as it applies to treatment and to new regulations for drug use in the equine athlete. - NEW advances in methods of transporting equine athletes ensure that the amount of stress on the athlete is kept to a minimum. - NEW rehabilitation techniques help to prepare the equine athlete for a return to the job. - Two NEW authors, Dr. Catherine McGowan and Dr. Kenneth McKeever, are highly recognized experts in the field.

Download or read book Arkansas DWI Defense written by John C. Collins and published by Lawyers & Judges Publishing Company Incorporated. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Colorado DUI Defense written by Jay M. Tiftickjian and published by Lawyers & Judges Publishing. This book was released on 2013 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: For even the most seasoned attorney admitted to practice in the State of Colorado, defending DUI cases has always presented special challenges. Today mounting a successful defense is more difficult than ever. Now you have the advantage with Colorado DUI Defense: The Law and Practice. This text and supplementary DVD contains the most important information to help you attain a successful verdict.Written by Jay M. Tiftickjian and James Nesci, both members of the National College for DUI Defense,Colorado DUI Defense: The Law and Practice ensures that you understand the chemical, biological and technological concepts and issues underlying DUI prosecution and defense in the State of Colorado. The authors provide the most up-to-date information available on key areas of DUI law in Colorado including: DUI Investigations, Driving and Field Sobriety Testing, Drug Recognition, Evaluation and Chemical Testing, Blood Alcohol Calculations, Pre-trial Investigations and Motions, Practice, Plea Offers and Agreements, DUI Trial Procedures, and more.Many practical tools and applications designed to streamline and simplify the complex DUI defense process have been developed along with this book. They are all included on a bonus DVD--so you can locate, review and print them out in a matter of seconds. The companion DVD contains NHTSA studies, articles and visual detection videos.

Download or read book Ohio DUI OVI Guide written by Shawn Dominy and published by . This book was released on 2021-03-17 with total page 49 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nobody anticipates being charged with DUI (called 'OVI' in Ohio). When it happens, people have a lot of questions. This guide is designed to answer those questions. If you have been charged with OVI in Ohio, the first thing you should do is educate yourself about OVI cases and OVI lawyers. This guide is a great way to do that.By reading this book, you will have the information you need before going to court. You will learn what the prosecution must prove for an OVI conviction and the possible defenses to OVI. You will also learn the consequences of an OVI conviction. You will become familiar with the evidence in OVI cases, and you will know what to expect in the court process.You will also receive the information you need before making decisions about your OVI case. This guide provides a framework to help you decide if you are going to fight the OVI and whether you want a lawyer. If you choose to hire a lawyer, this guide contains resources for researching lawyers, criteria to evaluate their qualifications, and questions to ask when you speak with them.With this valuable information, you will be equipped to make well-informed decisions about how to handle your OVI case.

Download or read book California Drunk Driving Defense written by Lawrence Taylor and published by . This book was released on 2016 with total page 1484 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Providing step-by-step instruction in defense of a drunk driving case in California, California Drunk Driving Defense outlines what to anticipate and how to prepare for DUI/DWI pretrial and trial proceedings. The authors provide information on sentencing, license suspension, and revocation, as well as strategy guidance regarding: Field evidence and the arresting officer; What to expect and how to prepare for pretrial and trial proceedings; Methods to challenge the Intoxilyzer, Intoximeter, and blood and urine analyses; Tasks for cross-examination of the chemical expert and the arresting officer; Professional responsibility issues; Civilian witnesses; Substantive offenses; Giving compelling jury instructions; Suppression of evidence, and Successfully attacking prior convictions" -- http://legalsolutions.thomsonreuters.com/law-products/Treatises/California-Drunk-Driving-Defense-5th/p/104310653

Download or read book Medical legal Aspects of Drugs written by Marcelline Burns and published by Lawyers and Judges Publishing. This book was released on 2007 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work addresses the challenge of the dynamic and pervasive problem of drug-use issues with accurate, cutting-edge information from acknowledged experts. Readers learn about diverse drug topics including illegal drugs, prescription drugs, drug use in the workplace or school, and drug use and criminal activity.

Download or read book Relentless Criminal Cross Examination written by Kevin J. Mahoney and published by LexisNexis. This book was released on 2018-03-30 with total page 2040 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to (1) persuasively open with the weaknesses you will expose in the government’s case, and (2) demonstrate those weaknesses through your cross-examinations. Themes, angles of attack, pattern Q&A, and technique tips for cross-examining arresting officers, detectives, toxicologists, medical examiners, eyewitnesses, informants, and accomplices.

Download or read book West Virginia DUI Defense written by Harley Wagner and published by Lawyers & Judges Publishing. This book was released on 2010 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: For even the most seasoned attorney admitted to practice in the State of West Virginia, defending DUI cases has always presented special challenges. Today mounting a successful defense is more difficult than ever. Now you have the advantage with West Virginia DUI Defense: The Law and Practice. This text and supplementary DVD contains the most important information to help you attain a successful verdict.Written by Harley O. Wagner and James Nesci, members of the National College for DUI Defense, West Virginia DUI: The Law and Practice ensures that you understand the chemical, biological and technological concepts and issues underlying DUI prosecution and defense in the State of West Virginia. The authors provide the most up-to-date information available on key areas of DUI law in West Virginia including: DUI Investigations, Driving and Field Sobriety Testing, Drug Recognition, Evaluation and Chemical Testing, Blood Alcohol Calculations, Pre-trial Investigations and Motions, Practice, Plea Offers and Agreements, DWI Trial Procedures, and more. Many practical tools and applications designed to streamline and simplify the complex DUI defense process have been developed along with this book. They are all included on a bonus DVD - so you can locate, review and print them out in a matter of seconds. The companion DVD contains NHTSA studies, articles and visual detection videos, as well as expanded sections on West Virginia law and procedure.

Download or read book Wisconsin OWI Defense written by Andrew Mishlove and published by Lawyers & Judges Publishing. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: For even the most seasoned attorney admitted to practice in the State of Wisconsin, defending OWI cases has always presented special challenges. Today, due to legislative developments, the introduction of blood alcohol-testing technologies, and an increasingly harsh prosecutorial climate, mounting a successful defense is more difficult than ever. That's why you will come to rely on Wisconsin OWI Defense: The Law and Practice. This reference book ensures that you understand the chemical, biological and technological concepts and issues underlying OWI prosecution and defense in the State of Wisconsin including: OWI Investigations, Driving & Field Sobriety Testing, Drug Recognition Evaluation and Chemical Testing, Blood Alcohol Calculations, Pre-trial Investigations and Motions, Practice, Plea Offers and Agreements, OWI Trial Procedures and more.

Download or read book Principles of Forensic Toxicology written by Barry Levine and published by Amer. Assoc. for Clinical Chemistry. This book was released on 2003 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: