Download or read book Disorders of Porphyrin Metabolism written by A. Goldberg and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each of the four authors of this book has a particular interest in disorders of porphyrin metabolism and special experience in their management. Their individual involvement in the field varies from 12 to 52 years and, combined, represents more than a century of personal experience. Since it has been written by both basic scientists and practicing physicians, the book is intended to be of value to all those involved in porphyrin metab olism and the porphyrias. It is hoped that the fascination of porphyrin metabolism and the clinical challenge of the porphyrias experienced by each of the authors will be conveyed to the readers. Michael R. Moore Kenneth E. L. McColl Claude Rimington Abraham Goldberg vii CONTENTS Color Plates ............................................ xvii 1. The History, Classification, and Incidence of the Porphyrias 1 1.1. History ........................................ 1 1.1.1. Early Chemistry . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 1.1.2. Early Descriptions of Porphyria .............. 4 1.1.3. Biochemical Developments .................. 4 1.1.4. Acute Porphyria . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 1.1.5. A Complete Pathway ...................... 8 1.2. Classification of the Porphyrias . . . . . . . . . . . . . . . . . . . . . 9 1.2.1. The Current Classification. . . . . . . . . . . . . . . 12 . . . .

Download or read book Diseases of the Liver and Bile Ducts written by George Y. Wu and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise, practical guide to the diagnosis and treatment of liver disease. Authoritative and practical, this important new book not only spells out the advantages and limitations of the latest diagnostic tests, but also provides numerous algorithms for evaluating patients and treating the liver problems commonly encountered by primary care physicians. Here, too, the reader will find described the nuances of serological tests for the detection of viral infections and how best to use invasive and noninvasive radiological tests in specific circumstances. Common complications are fully discussed and detailed practical information is given on how to recognize the patient's immediate problems and deal with them effectively. This book's numerous diagrams, clinical "pearls", and cost comparisons will clarify the often complex and bewildering array of conditions associated with liver disease and make it a definitive and indispensable guide for primary care physicians, medical students, and residents.

Download or read book Hematology in Clinical Practice Fifth Edition written by Robert S. Hillman and published by McGraw Hill Professional. This book was released on 2010-10-22 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most practical and efficient guide to the diagnosis and management of blood disorders – now in full color 200 full-color illustrations! Hematology in Clinical Practice is a succinct, cutting-edge guide to the diagnosis and treatment of disorders of red blood cells, white blood cells, and hemostasis, and the use of blood components for transfusion. Each disease state is discussed in detail, incorporating the pathophysiology, clinical features, up-to-date laboratory testing, and current management strategies into a comprehensive and practical approach to hematologic disorders. Features: New full-color presentation includes over 200 superb illustrations and classic images of blood morphology, tissue pathology, and clinical findings New Case Histories introduce and continue through relevant chapters, highlighting critical clinical points for diagnosis and management New end-of-chapter Points to Remember encapsulate key clinical information New chapters include Anemia in the Elderly and expanded and updated coverage of Transplantation and treatment of hematologic malignancies Outstanding collection of tables, charts, and illustrations that translate basic science into valuable clinical context Strong focus on practical clinical management and supportive care Coverage of state-of-the-art drugs and chemotherapies and the latest advances in genetic testing and molecular pathways Conveniently organized into sections on Red Cells, White Cells, Hemostasis, and Transfusion Medicine

Download or read book Handbook of Benign Hematology written by Martha Pritchett Mims, MD, PhD and published by Springer Publishing Company. This book was released on 2019-12-11 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Benign Hematology is a practical guide to the diagnosis and management of benign hematologic conditions. The book begins with a chapter on normal hematopoiesis and follows with chapters devoted to groups of blood disorders and syndromes including neutrophil disorders, nonmalignant myeloid disorders, bone marrow failure syndromes, myeloproliferative disorders, anemias, iron metabolism disorders, platelet disorders, hemostasis and coagulation defects, and thrombosis. Each disorder subtype covered features a clinical case, an introduction to the condition, details on diagnosis including applicable criteria and lab work needed, key diagnostic dilemmas, prognosis, treatment options, details on clinical trials and emerging clinical strategies, and bulleted key points to highlight clinical pearls and common pitfalls. The final chapters provide best practices for transfusion medicine and a guide to pharmacologic agents and their uses in clinical practice for adult and pediatric patients. The handbook is filled with tables and illustrations which highlight FDA-approved drug information, clinical trials data, hematopathologic characteristics of different disorders, important management criteria and more, making it the ideal handbook for those in practice or for review. The Editors and chapter authors are experienced academic practitioners in the fields of adult and pediatric hematology, pathology, blood banking, and pharmacology. Emphasizing best practices for patient management, this handbook is essential for oncologists, hematologists, trainees, and other practitioners who regularly or increasingly receive referrals to diagnose and treat adults or children with nonmalignant hematologic conditions. Key Features: Includes dozens of clinical cases covering all nonmalignant blood disorders Emphasizes patient management and best practices for disorders seen in adults and children Contains over 30 color images and numerous tables for quick reference Presents important details of all pharmacologic agents used to treat or manage hematologic disorders and their complications Purchase includes access to the ebook for use on most mobile devices or computers

Download or read book Inborn Metabolic Diseases written by K. Tada and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each disease-related chapter begins with a detailed description of the patient and the delineating symptoms used for establishing the diagnosis and differential diagnosis. The highly detailed figures illustrate the metabolic derangement in a uniform way, together with essential aspects of the genetics involved, thus affording clarification and better understanding of the treatment. Topics covered range from general aspects such as the clinical approach, emergency treatment, diagnostic procedures, and psychosocial care for the child and the family, to specific discussions of new modes of treatment, including liver, bone marrow transplantation and somatic gene therapy.

Download or read book Liver Disease in Children written by Frederick J. Suchy and published by Cambridge University Press. This book was released on 2021-03-18 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver disease in children is increasing in prevalence, placing a huge burden on healthcare systems and often requiring long-term management. Offering an integrative approach to the science and clinical practice of pediatric hepatology, this is the definitive reference text for improved diagnosis and treatment strategies. In the new edition of this authoritative text, chapters have been thoroughly revised in line with major advances in the field, such as recognizing the increased frequency of fatty liver disease, and how genetic testing has the potential to establish earlier diagnoses for a variety of diseases. Disorders covered include cholestasis, metabolic disorders and hepatitis, with their presentation across the spectrum of infancy, childhood and adolescence discussed. The indications and surgical aspects of liver transplant are explained and post-transplant care is described in detail. This is a valuable resource for pediatricians, hepatologists, gastroenterologists and all clinicians involved in the care of children with liver diseases.

Download or read book Diseases of Porphyrin Metabolism written by Abraham Goldberg and published by . This book was released on 1962 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Physician s Guide to the Diagnosis Treatment and Follow Up of Inherited Metabolic Diseases written by Nenad Blau and published by Springer. This book was released on 2014-07-08 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, combining and updating two previous editions, is a unique source of information on the diagnosis, treatment, and follow-up of metabolic diseases. The clinical and laboratory data characteristic of rare metabolic conditions can be bewildering for both clinicians and laboratory personnel. Reference laboratory data are scattered, and clinical descriptions may be obscure. The Physician’s Guide documents the features of more than five hundred conditions, grouped according to type of disorder, organ system affected (e.g. liver, kidney, etc) or phenotype (e.g. neurological, hepatic, etc). Relevant clinical findings are provided and pathological values for diagnostic metabolites highlighted. Guidance on appropriate biochemical genetic testing is provided. Established experimental therapeutic protocols are described, with recommendations on follow-up and monitoring. The authors are acknowledged experts, and the book will be a valuable desk reference for all who deal with inherited metabolic diseases.

Download or read book The Porphyrias written by Geoffrey Dean and published by . This book was released on 1971 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Dermatological Manifestations of Kidney Disease written by Julia R. Nunley and published by Springer. This book was released on 2015-07-03 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly all patients with chronic kidney disease (CKD) have at least one significant dermatologic manifestation. This all-inclusive reference covers the wide array of cutaneous manifestations attributable to CKD, kidney transplantation and the pharmacological aspects of the disease process. Each chapter provides pathobiology, extensive clinical discussions, full-color images and in-depth treatment options. Dermatological Manifestations of Kidney Disease helps the practitioner, nephrologist, resident and student recognize, appropriately evaluate and treat these conditions more effectively.

Download or read book Atlas of the Liver written by Willis C. Maddrey and published by Springer Science & Business Media. This book was released on 2013-12-18 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the third edition of the Atlas of the Liver, the authors present (and evaluate) many crucial concepts regarding liver disease using photomicrographs, charts and, tables. The goal of the Atlas of the Liver is to augment comprehensive texts. Every major hepatic disease is thoroughly addressed, along with guidance as to the most efficient and effective ways to treat them. Dr. Willis Maddrey, along with 24 leading hepatologists, has interwoven concepts from fields such as molecular biology with the results of clinical observations and trials in order to facilitate efficient, accurate diagnosis and the use of effective therapy.

Download or read book NORD Guide to Rare Disorders written by National Organization for Rare Disorders and published by Lippincott Williams & Wilkins. This book was released on 2003 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: NORD Guide to Rare Disorders is a comprehensive, practical, authoritative guide to the diagnosis and management of more than 800 rare diseases. The diseases are discussed in a uniform, easy-to-follow format--a brief description, signs and symptoms, etiology, related disorders, epidemiology, standard treatment, investigational treatment, resources, and references.The book includes a complete directory of orphan drugs, a full-color atlas of visual diagnostic signs, and a Master Resource List of support groups and helpful organizations. An index of symptoms and key words offers physicians valuable assistance in finding the information they need quickly.

Download or read book Decision Making in Anesthesiology written by Lois L. Bready and published by Elsevier Health Sciences. This book was released on 2007-01-01 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines vital topics in pre-anesthesia assessment, pre-operative problems, resuscitation, specialty anesthesia, post-operative management, and more. Its unique algorithmic approach helps you find the information you need quickly--and gives you insights into the problem-solving techniques of experienced anesthesiologists.

Download or read book Harderian Glands written by Susan M. Webb and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Harderian glands, first described by Jacob Harder in two species of deer in 1694, are large, intraorbital glands which, with but few exceptions, are found in all land vertebrates. Certainly, their relatively large size, their phylogenetic age, and persistent conservation in all groups as they emerged from an aqueous to an air/land environment lend strong support to the logical deduction that they probably play an important role in the physiological adaptation to terrestrial life. Yet, few biologists know even what or where these glands are. For a variety of reasons, the Harderian glands have not received the attention they deserve and, as a result, the published works available have been scarce and scattered throughout the world literature. The current situation is remarkably similar to that which existed in regard to the pineal gland prior to the mid-1960s, i. e. , scattered literature, unknown function, few investigators, and little interest. Yet, following a few key papers, interest in the pineal gland expanded and soon an explosive increase in the knowledge and understanding of the pineal gland took place and continues today. Will history repeat itself? Originally, a few of us discussed the desirability of an informal Symposium on the Harderian glands.

Download or read book Metabolic Diseases written by E. Gilbert-Barness and published by IOS Press. This book was released on 2017-01-06 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2nd Edition of Metabolic Diseases provides readers with a completely updated description of the Foundations of Clinical Management, Genetics, and Pathology. A distinguished group of 31 expert authors has contributed 25 chapters as a tribute to Enid Gilbert-Barness and the late Lewis Barness--- both pioneers in this topic. Enid’s unique perspectives on the pathology of genetic disorders and Lew’s unsurpassed knowledge of metabolism integrated with nutrition have inspired the contributors to write interdisciplinary descriptions of generally rare, and always challenging, hereditary metabolic disorders. Discussions of these interesting genetic disorders are organized in the perspective of molecular abnormalities leading to morphologic disturbances with distinct pathology and clinical manifestations. The book emphasizes recent advances such as development of improved diagnostic methods and discovery of new, more effective therapies for many of the diseases. It includes optimal strategies for diagnosis and information on access to specialized laboratories for specific testing. The target audience is a wide variety of clinicians, including pediatricians, neonatologists, obstetricians, maternal-fetal specialists, internists, pathologists, geneticists, and laboratorians engaged in prenatal and/or neonatal screening. In addition, all scientists and health science professionals interested in metabolic diseases will find the comprehensive, integrated chapters informative on the latest discoveries. It is our hope that the 2nd Edition will open new avenues and vistas for our readers and that they will share with us the interest, excitement and passion of the research into all these challenging disorders.

Download or read book Oxford Handbook of Anaesthesia written by Keith Allman and published by . This book was released on 2006 with total page 1229 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Handbook of Anaesthesia has been completely updated for the second edition. All chapters have been rewritten and a number of new expert authors have been brought on board. Additional new material includes anaesthesia for the critically ill, and a comprehensive section on anaesthetic risk including anaesthetic risk tables. The first section deals with preoperative issues affecting the administration of anaesthesia. Practical advice is provided covering the impact of medical disease on anaesthesia. The second section describes practical anaesthetic techniques for surgical specialties, including most subspecialties such as thoracic and neuroanaesthesia. Separate, comprehensive sections on paediatric and obstetric anaesthesia are included. The management of emergencies arising during anaesthesia are fully covered with helpful action plans and algorithms throughout. Uncommon conditions and their management are included, and there is an extensive drug formulary and guide to infusion drugs. As with the first edition, this new edition will be the essential handbook for anaesthetists, both junior and experienced, for registrars and those sitting exams, as well as ODPs and nurses involved in theatre area work and pre-assessment. It is the one book for anyone working in anaesthesia to keep to hand at all times!

Download or read book Brain Disorders in Critical Illness written by Robert D. Stevens and published by Cambridge University Press. This book was released on 2013-09-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.