Download or read book Diffuse Optical Tomography System in Soft Tissue Tumor Detection written by Umamaheswari Kumarasamy and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topical review of recent trends in Modeling and Regularization methods of Diffuse Optical Tomography (DOT) system promotes the optimization of the forward and inverse modeling methods which provides a 3D cauterization at a faster rate of 40frames/second with the help of a laser torch as a hand-held device. Analytical, Numerical and Statistical methods are reviewed for forward and inverse models in an optical imaging modality. The advancement in computational methods is discussed for forward and inverse models along with Optimization techniques using Artificial Neural Networks (ANN), Genetic Algorithm (GA) and Artificial Neuro Fuzzy Inference System (ANFIS). The studies carried on optimization techniques offers better spatial resolution which improves quality and quantity of optical images used for morphological tissues comparable to breast and brain in Near Infrared (NIR) light. Forward problem is based on the location of sources and detectors solved statistically by Monte Carlo simulations. Inverse problem or closeness in optical image reconstruction is moderated by different regularization techniques to improve the spatial and temporal resolution. Compared to conventional methods the ANFIS structure of optimization for forward and inverse modeling provides early detection of Malignant and Benign tumor thus saves the patient from the mortality of the disease. The ANFIS technique integrated with hardware provides the dynamic 3D image acquisition with the help of NIR light at a rapid rate. Thereby the DOT system is used to continuously monitor the Oxy and Deoxyhemoglobin changes on the tissue oncology.

Download or read book Optical Detection of Cancer written by Arlen D. Meyers and published by World Scientific. This book was released on 2012 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ch. 1. The optical detection of cancer: an introduction / Toby Steele and Arlen Meyers -- ch. 2. Optical coherence tomography in oral cancer / Shahareh Sabet and Petra Wilder-Smith -- ch. 3. Optical coherence tomography in laryngeal cancer / Marcel Kraft and Christoph Arens -- ch. 4. Fluorescence imaging of the upper aerodigestive tract / Christian Stephan Betz, Andreas Leunig and Christoph Arens -- ch. 5. Photodynamic diagnosis and photodynamic therapy techniques / Zheng Huang -- ch. 6. OCT detection of lung cancer / S. Murgu and M. Brenner -- ch. 7. Diffuse optical spectroscopy and imaging in breast cancer / Albert E. Cerussi and Bruce J. Tromberg -- ch. 8. OCT for skin cancer / Gordon McKenzie and Adam Meekings

Download or read book Diffuse Optical Tomography written by Huabei Jiang and published by CRC Press. This book was released on 2018-09-03 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by an authority involved in the field since its nascent stages, Diffuse Optical Tomography: Principles and Applications is a long-awaited profile of a revolutionary imaging method. Diffuse Optical Tomography (DOT) provides spatial distributions of intrinsic tissue optical properties or molecular contrast agents through model-based reconstruction algorithms using NIR measurements along or near the boundary of tissue. Despite the practical value of DOT, many engineers from electrical or applied mathematics backgrounds do not have a sufficient understanding of its vast clinical applications and portability value, or its uncommon advantages as a tool for obtaining functional, cellular, and molecular parameters. A collection of the author’s research and experience, this book fuses historical perspective and experiential anecdotes with fundamental principles and vital technical information needed to successfully apply this technology—particularly in medical imaging. This reference finally outlines how to use DOT to create experimental image systems and adapt the results of laboratory studies for use in clinical applications including: Early-stage detection of breast tumors and prostate cancer "Real-time" functional brain imaging Joint imaging to treat progressive diseases such as arthritis Monitoring of tumor response New contrast mechanisms and multimodality methods This book covers almost every aspect of DOT—including reconstruction algorithms based on nonlinear iterative Newton methods, instrumentation and calibration methods in both continuous-wave and frequency domains, and important issues of imaging contrast and spatial resolution. It also addresses phantom experiments and the development of various image-enhancing schemes, and it describes reconstruction methods based on contrast agents and fluorescence DOT. Offering a concise description of the particular problems involved in optical tomography, this reference illustrates DOT’s fundamental foundations and the principle of image reconstruction. It thoroughly explores computational methods, forward mathematical models, and inverse strategies, clearly illustrating solutions to key equations.

Download or read book Compact and Robust Ultrasound guided Diffuse Optical Tomography for Breast Imaging System and Algorithm Developments written by Hamed Vavadi and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the World Health Organization, breast cancer is the most common cancer among women worldwide, claiming lives of hundreds of thousands of women each year. Mammography, ultrasound (US) and magnetic resonance imaging (MRI) are widely used to detect and diagnose breast lesions and each of them have some disadvantages which motivates researchers to find a new and high sensitive imaging method. Diffuse optical tomography (DOT) is a noninvasive functional imaging modality that utilizes near-infrared (NIR) light to probe tissue optical properties. Minimal light absorption in the NIR spectrum allows for several centimeters of light penetration in soft tissue. NIR is sensitive to hemoglobin which is directly related to tumor angiogenesis. If multiple wavelengths are used, it can probe tumor oxygen saturation. However, DOT has drawbacks on location uncertainty and low light quantification accuracy due to tissue scattering of NIR light. Ultrasound (US)-guided Diffuse Optical Tomography has overcome these problems. The overall objective of my research is to move US-guided DOT one step closer from a research imaging modality to a commercial prototype for future wide use in clinics. To achieve this goal, I have overcome several challenges in both imaging hardware and software. In this Dissertation, I will discuss the progress we have made on development of two generations of US-guided DOT systems along with the software improvements. The developed systems have been improved in terms of robustness, stability, clinical safety and standards and user friendliness. In terms of software and algorithm development, automated methods for data selection, outlier removal and reference and perturbation filtering are presented. These methods have improved the robustness of the technique and increased speed of image formation by eliminating the need for an expert to perform data preprocessing and data selection. Phantom and clinical experimental results will be demonstrated to evaluate the performance of the developed systems and algorithms.

Download or read book Tumor Detection Using Bayesian Conjugate Prior in Diffuse Optical Tomography written by Heeralal Choudhary and published by . This book was released on 2006 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Optical Tomography and Spectroscopy of Tissue VI written by Britton Chance and published by SPIE-International Society for Optical Engineering. This book was released on 2005 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of SPIE offer access to the latest innovations in research and technology and are among the most cited references in patent literature.

Download or read book Dynamic Digital Optical Tomography for Cancer Imaging and Therapy Monitoring written by Molly Flexman and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffuse optical tomography is a non-invasive imaging technique that uses near-infrared light to create three-dimensional images of tissue. This dissertation presents the design and validation of an instrument for rapid optical imaging using digital detection techniques. In addition to a detailed description of the instrument, three studies are presented: a clinical study detecting breast cancer using dynamic optical imaging; a pre-clinical study monitoring early tumor response to anti-angiogenic therapy; and a clinical study monitoring individual patient response to neoadjuvant chemotherapy. These studies show that diffuse optical tomography is a valuable imaging modality that can play an important role in cancer detection and treatment.

Download or read book Diffuse Optical Tomography written by Ruixin Jiang and published by . This book was released on 2012 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffuse Optical Tomography has drawn more and more interests in the biomedical field over the recent couple of decades due to its ability to noninvasively recover not only tissue structural information but also functional and molecular properties. The contrasts that optical parameters could demonstrate in DOT are usually higher than those of the conventional methods. Based on these contrasts, different approaches had been developed applying DOT for imaging, and so far lots of efforts were spent on detecting breast cancer by imaging tissue absorption and scattering coefficients as well as hemoglobin concentration and oxygen saturation level. In this work, we tried to expand the ability of DOT in breast cancer detection by introducing Phase-contrast diffuse optical tomography (PCDOT). PCDOT uses near-infrared diffusing light to non-invasively reconstruct tissue refractive index (RI) distribution. RI depends on the tissue's physical and chemical properties and previous study revealed that it might serve as a promising imaging parameter in breast cancer detection. We've first developed a 2-step method to improve the PCDOT image both qualitatively and quantitatively at single-wavelength; then we've introduced a multispectral PCDOT algorithm to more efficiently reconstruct RI simultaneously with other tissue functional parameters and attempted to improve this algorithm by different structural regularization methods.

Download or read book Soft Tissue Image Reconstruction Using Diffuse Optical Tomography written by Umamaheswari Kumarasamy and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffuse optical tomography (DOT) is favorable to analyze physical records in organic tissue with a specific purpose by means of a method related to the forward problem and the inverse solution. This study develops morphological soft tissue realization using an image reconstruction algorithm constructed on multifrequency DOT in Near-Infra-Red (NIR) wavelength. Forward problem solves the Diffusion Equation to compute the optical flux distributed in the phantom geometrical model. Inverse solution, the image is reconstructed using the absorption and reduced scattered coefficients under different boundary conditions. The inverse image reconstruction algorithm is tested for several simulation, with variation in background contrast ratios for different frequencies are simulated. The image reconstruction in DOT eliminates spatial resolution by optimizing source-detector separation and modulation intensities of the source.

Download or read book A Continuous Wave Diffusion Optical Tomography System Based on High Accuracy Multidimensional Imaging Reconstruction Model for Breast Tumor Detection written by and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A Diffuse Optical Tomography System on Chip Design for Breast Tumor Imaging System Based on Three Dimensional Multiple Layer Reconstruction Algorithm written by and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Molecular Diffuse Optical Tomography for Early Breast Cancer Detection and Characterization written by Vasilis Ntziachristos and published by . This book was released on 2001 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: Herein we demonstrate the construction of the first reported fluorescence animal tomographer for molecular investigations of cancer-associated expression patterns. Using inversion techniques that account for the diffuse nature of photon propagation in tissue and near infrared fluorescent molecular beacons we were able to obtain three-dimensional in-vivo images of cathepsin B expression of orthopic gliomas. We demonstrate that fluorescent probes, activated by carcinogenesis, can be detected with high positional accuracy and high sensitivity in deep tissues, that molecular specificities of different beacons towards enzymes can be resolved, and that tomography of beacon activation is linearly related to enzyme concentration. The tomographic imaging method offers a range of new capabilities for studying biological function using fluorescent chemical sensors, for identifying molecular expression patterns via multispectral imaging and for continuously monitoring drug therapies. It is envisaged that molecular sensing will significantly improve the detection capacity of early cancer since malignancy identification is based on the molecular signals responsible for carcinogenesis and not on structural or functional tissue changes inflicted by well-formed cancers that are currently targeted by traditional medical imaging techniques.

Download or read book Contrast Enhancement for Diffuse Optical Spectroscopy and Imaging written by Yu Chen and published by . This book was released on 2003 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Waves and Imaging through Complex Media written by P. Sebbah and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in wave propagation in random media are certainly consequences of new approaches to fundamental issues, as well as of a strong interest in potential applications. A collective effort has been made to present in this book the state of the art in fundamental concepts, as well as in biomedical imaging techniques. As an example, the recent introduction of wave chaos, and more specifically random matrix theory - an old tool from nuclear physics - to the study of multiple scattering, has pointed the way to a deeper understanding of wave coherence in complex media. At the same time, efficient new approaches for retrieving information from random media promise to allow wave imaging of small tumors in opaque tissues. Review chapters are written by experts in the field, with the aim of making the book accessible to the widest possible scientific audience: graduate students and research scientists in theoretical and applied physics, optics, acoustics, and biomedical physics.

Download or read book Digital Image Processing Applications written by Paulo Ambrosio and published by BoD – Books on Demand. This book was released on 2022-04-20 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digital image processing can refer to a wide variety of techniques, concepts, and applications of different types of processing for different purposes. This book provides examples of digital image processing applications and presents recent research on processing concepts and techniques. Chapters cover such topics as image processing in medical physics, binarization, video processing, and more.

Download or read book Biophotonics for Medical Applications written by Igor Meglinski and published by Elsevier. This book was released on 2015-06-29 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophotonics for Medical Applications presents information on the interface between laser optics and cell biology/medicine. The book discusses the development and application of photonic techniques that aid the diagnosis and therapeutics of biological tissues in both healthy and diseased states. Chapters cover the fundamental technologies used in biophotonics and a wide range of therapeutic and diagnostic applications. - Presents information on the interface between laser optics and cell biology/medicine - Discusses the development and application of photonic techniques which aid the diagnosis and therapeutics of biological tissues in both healthy and diseased states - Presents the fundamental technologies used in biophotonics and a wide range of therapeutic and diagnostic applications

Download or read book Biomedical Engineering in Gastrointestinal Surgery written by Armin Schneider and published by Academic Press. This book was released on 2017-06-27 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Engineering in Gastrointestinal Surgery is a combination of engineering and surgical experience on the role of engineering in gastrointestinal surgery. There is currently no other book that combines engineering and clinical issues in this field, while engineering is becoming more and more important in surgery. This book is written to a high technical level, but also contains clear explanations of clinical conditions and clinical needs for engineers and students. Chapters covering anatomy and physiology are comprehensive and easy to understand for non-surgeons, while technologies are put into the context of surgical disease and anatomy for engineers. The authors are the two most senior members of the Institute for Minimally Invasive Interdisciplinary Therapeutic Interventions (MITI), which is pioneering this kind of collaboration between engineers and clinicians in minimally invasive surgery. MITI is an interdisciplinary platform for collaborative work of surgeons, gastroenterologists, biomedical engineers and industrial companies with mechanical and electronic workshops, dry laboratories and comprehensive facilities for animal studies as well as a fully integrated clinical "OR of the future". - Written by the head of the Institute of Minimally Invasive Interdisciplinary Therapeutic Intervention (TUM MITI) which focusses on interdisciplinary cooperation in visceral medicine - Provides medical and anatomical knowledge for engineers and puts technology in the context of surgical disease and anatomy - Helps clinicians understand the technology, and use it safely and efficiently