Download or read book Design Synthesis and Evaluation of Some Novel Antiviral Nucleoside Analogues written by Andrea Brancale and published by . This book was released on 2001 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Design Synthesis and Evaluation of Some Novel Antiviral Nucleosides written by Annette Angell and published by . This book was released on 2005 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies in the Design Synthesis and Biological Evaluation of Some Novel Antiviral Nucleosides and Nucleotides written by Sally Ann Blewett and published by . This book was released on 2001 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Design Synthesis and Biological Evaluation of Novel Nucleoside Analogues as Potential Antiviral Agents written by Giovanna Luoni and published by . This book was released on 2004 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Design Synthesis and Biological Evaluation of Novel Nucleoside Analogues as Potential Antiviral Agents written by Olivier Bidet and published by . This book was released on 2003 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Design Synthesis and Biological Evaluation of Novel Nucleoside Analogues as Potential Antiviral Agents written by Antonella Carangio and published by . This book was released on 2002 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chemical Synthesis of Nucleoside Analogues written by Pedro Merino and published by John Wiley & Sons. This book was released on 2013-02-12 with total page 859 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compiles current tested and proven approaches to synthesize novel nucleoside analogues Featuring contributions from leading synthetic chemists from around the world, this book brings together and describes tested and proven approaches for the chemical synthesis of common families of nucleoside analogues. Readers will learn to create new nucleoside analogues with desired therapeutic properties by using a variety of methods to chemically modify natural nucleosides, including: Changes to the heterocyclic base Modification of substituents at the sugar ring Replacement of the furanose ring by a different carbo- or heterocyclic ring Introduction of conformational restrictions Synthesis of enantiomers Preparation of hydrolitically stable C-nucleosides Chemical Synthesis of Nucleoside Analogues covers all the major classes of nucleosides, including pronucleotides, C-nucleosides, carbanucleosides, and PNA monomers which have shown great promise as starting points for the synthesis of nucleoside analogues. The book also includes experimental procedures for key reactions related to the synthesis of nucleoside analogues, providing a valuable tool for the preparation of a number of different compounds. Throughout the book, chemical schemes and figures help readers better understand the chemical structures of nucleoside analogues and the methods used to synthesize them. Extensive references serve as a gateway to the growing body of original research studies and reviews in the field. Synthetically modified nucleosides have proven their value as therapeutic drugs, in particular as antiviral and antitumor agents. However, many of these nucleoside analogues have undesirable side effects. With Chemical Synthesis of Nucleoside Analogues as their guide, researchers have a new tool for synthesizing a new generation of nucleoside analogues that can be used as therapeutic drugs with fewer unwanted side effects.

Download or read book Studies in the Design Synthesis and Biological Evaluation of Some Novel Antiviral Nuclesides and Nucleotides written by Sally Ann Blewett and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthesis and in Vitro Evaluation of Some Novel Nucleoside Analogs and DNA Intercalators as Potential Anticancer and Antiviral Agents written by Yuxiang Zhao and published by . This book was released on 2007 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the second project, the synthesis of three series of bis-aminochloropyrimidine derivatives with different types of linkers as potential DNA intercalators is described. The first series are aminochloropyrimidines bridged by polymethylene chain linkers with various lengths. The second series are bridged by polyether linkers to lower the lipophilicity. The third series are bridged by linkers containing benzene rings to limit the flexibility. The spectral data and other physical properties of the new compounds are discussed. The preliminary screening results indicate that many new synthesized bis-intercalators are biologically active. The relationship between bioactivity and structure is discussed as well.

Download or read book Design Synthesis Antiviral Evaluation and Metabolism of Nucleoside Analogs written by Jocelyn Edathil and published by . This book was released on 2008 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Computer aided Design Synthesis and Evaluation of Novel Antiviral Compounds written by Michela Cancellieri and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthesis and Evaluation of Some Novel Nucleoside Derivatives as Potential Anti AIDS Drugs written by and published by . This book was released on 1990 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Design Synthesis and Evaluation of Some Chemotherapeutic Nucleosides and Nucleotides written by Federica Gavazza and published by . This book was released on 2005 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Advances in Antiviral Drug Design written by E. De Clercq and published by Elsevier. This book was released on 2007-07-30 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of action, pharmacological behavior, antiviral activity spectrum, and therapeutic potential for clinical use.

Download or read book BRS Biochemistry Molecular Biology and Genetics written by Michael A. Lieberman and published by Lippincott Williams & Wilkins. This book was released on 2019-01-09 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Practical, approachable, and perfect for today’s busy medical students and practitioners, BRS Biochemistry, Molecular Biology, and Genetics, Seventh Edition helps ensure excellence in class exams and on the USMLE Step 1. The popular Board Review Series outline format keeps content succinct and accessible for the most efficient review, accompanied by bolded key terms, detailed figures, quick-reference tables, and other aids that highlight important concepts and reinforce understanding. This revised edition is updated to reflect the latest perspectives in biochemistry, molecular biology, and genetics, with a clinical emphasis essential to success in practice. New Clinical Correlation boxes detail the real-world application of chapter concepts, and updated USMLE-style questions with answers test retention and enhance preparation for board exams and beyond.

Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Download or read book Carbohydrate Chemistry written by Paul Kosma and published by CRC Press. This book was released on 2021-01-14 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irreproducibility of synthetic protocols, lack of identification and characterization data for new compounds, and inflated yields reported in chemical communications—trends that have recently become a serious problem. Exploring carbohydrate chemistry from both the academic and industrial points of view, this unique resource brings together useful information into one convenient reference. The series is unique among other synthetic literature in the carbohydrate field in that, to ensure reproducibility, an independent checker has verified the experimental parts involved by repeating the protocols or using the methods. Featuring contributions from world-renowned experts and overseen by a highly respected series editor, this latest volume compiles reliable protocols for the preparation of intermediates for carbohydrate synthesis or other uses in the glycosciences. Key Features: Explains reliable and tested protocols for the preparation of intermediates for carbohydrate synthesis Offers a unique resource in glycosciences, compiling useful information in one reference Presents protocols that are of wide use to a broad range of readers in the carbohydrate field and the life sciences, including undergraduates taking carbohydrate workshops Explores synthetic carbohydrate chemistry from both the academic and industrial points of view Guarantees the reader a good, clean, reproducible experiment