Download or read book Antimicrobial Drugs written by David Greenwood and published by Oxford University Press. This book was released on 2008-02-21 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Between 1935 and 1944 the field of microbiology, and by implication medicine as a whole, underwent dramatic advancement. The discovery of the extraordinary antibacterial properties of sulphonamides, penicillin, and streptomycin triggered a frantic hunt for more antimicrobial drugs that was to yield an abundant harvest in a very short space of time. By the early 1960s more than 50 antibacterial agents were available to the prescribing physician and, largely by a process of chemicalmodification of existing compounds, that number has more than tripled today. We have become so used to the ready availability of these relatively safe and highly effective 'miracle drugs' that it is now hard to grasp how they transformed the treatment of infection.This book documents the progress made from the first tentative search for an elusive 'chemotherapy' of infection in the early days of the twentieth century, to the development of effective antiviral agents for the management of HIV as the millennium drew to a close. It also offers a celebration of the individuals and groups that made this miracle happen, as well as examining the inexorable rise of the global pharmaceutical industry, and, most intriguingly, the essential input of luck.Infection still maintains a high profile in both medicine and the media, with the current threats of 'superbugs' such as MRSA acquired in hospital, and a potential resistance to antibiotics. This book tracks the history of antimicrobial drugs, a remarkable medical triumph that has provided doctors with an amazing armoury of safe and effective drugs that ensure that reversion to the helpless state of the fight against infection witnessed in the early 1900s is extremely unlikely. This timelycompendium acknowledges the agents that have surely led to the relief of more human and animal suffering than any other class of drugs in the history of medical endeavour.
Download or read book Antibiotic Policies written by Ian M. Gould and published by Springer Science & Business Media. This book was released on 2006-01-26 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: For 50 years, antibiotics have been dispensed like sweets. This must not be allowed to continue. This unique book assembles contributions from experts around the world concerned with responsible use of antibiotics and the consequences of overuse. For the first time, it provides up to the minute texts on both the theoretical aspects of antibiotic stewardship and the practical aspects of its implementation, with consideration of the key differences between developed and developing countries. All concerned with teaching, practice and administration of clinical medicine, surgery, pharmacy, public health, clinical pharmacology, microbiology, infectious diseases and clinical therapeutics will find Antibiotic Policies: Theory and Practice essential reading. Antibiotic use and resistance is not just the responsibility of specialists in the field but the responsibility of all doctors, pharmacists, nurses, healthcare administrators, patients and the general public.
Download or read book Emerging Infectious Diseases written by and published by . This book was released on 2001 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Antimicrobial Resistance written by E. J. L. Soulsby and published by . This book was released on 2001 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Extending the Cure written by Ramanan Laxminarayan and published by Routledge. This book was released on 2010-09-30 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our ability to treat common bacterial infections with antibiotics goes back only 65 years. However, the authors of this report make it clear that sustaining a supply of effective and affordable antibiotics cannot be without changes to the incentives facing patients, physicians, hospitals, insurers, and pharmaceutical manufacturers. In fact, increasing resistance to these drugs is already exacting a terrible price. Every day in the United States, approximately 172 men, women, and children die from infections caused by antibiotic-resistant bacteria in hospitals alone. Beyond those deaths, antibiotic resistance is costing billions of dollars through prolonged hospital stays and the need for doctors to resort to ever more costly drugs to use as substitute treatments. Extending the Cure presents the problem of antibiotic resistance as a conflict between individual decision makers and their short-term interest and the interest of society as a whole, in both present and future: The effort that doctors make to please each patient by prescribing a drug when it might not be properly indicated, poor monitoring of discharged patients to ensure that they do not transmit drug-resistant pathogens to other persons, excesses in the marketing of new antibiotics, and the broad overuse of antibiotics all contribute to the development and spread of antibiotic-resistant bacteria. The book explores a range of policy options that would encourage patients, health care providers, and managed care organizations to serve as more responsible stewards of existing antibiotics as well as proposals that would give pharmaceutical firms greater incentives to develop new antibiotics and avoid overselling. If the problem continues unaddressed, antibiotic resistance has the potential to derail the health care system and return us to a world where people of all ages routinely die from simple infections. As a basis for future research and a spur to a critically important dialogue, Extending the Cure is a fundamental first step in addressing this public health crisis. The Extending the Cure project is funded in part by the Robert Wood Johnson Foundation through its Pioneer Portfolio.
Download or read book Infection Prevention and Control written by Debbie Weston and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with all of the background information necessary to enhance their understanding of the rationale behind the basic principles of infection control and how to apply them in every day situations; how specific bacteria interact with the host and cause infection; the background to each of the bacteria/infections described within the text, and, evidence based recommendations on the infection control management of these.
Download or read book When Antibiotics Fail written by The Expert Panel on the Potential Socio-Economic Impacts of Antimicrobial Resistance in Canada and published by Council of Canadian Academies. This book was released on 2019-11-12 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Antibiotics Fail examines the current impacts of AMR on our healthcare system, projects the future impact on Canada’s GDP, and looks at how widespread resistance will influence the day-to-day lives of Canadians. The report examines these issues through a One Health lens, recognizing the interconnected nature of AMR, from healthcare settings to the environment to the agriculture sector. It is the most comprehensive report to date on the economic impact of AMR in Canada.
Download or read book The Great Food Gamble written by John Humphrys and published by Hodder & Stoughton. This book was released on 2012-09-27 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Compelling' OBSERVER 'Humphrys' level-headedness makes the arguments all the more powerful' SUNDAY TIMES 'A concise, no-nonsense assessment of the true cost of cheap food: to the environment, the livestock, and the nation's long-term health' DAILY MAIL 'A passionate discourse ... well-written and accessible' INDEPENDENT * * * * * * * * * John Humphrys is passionate about the state of British food, farming, fishing and agriculture. Here, he looks back to the days of organic farming in England when people shared and swapped food and considered the wildlife as well as the farmed animals, crops and fruits. He examines today's travesties: factory farming, pouring chemicals into the land, the scandal of the supermarket wars and cheap imported goods. He then turns to the future and asks: Can we save this ravaged earth and rebuild our community values? Most of all, can we reverse the damage to ourselves and our long-term health that may result from what we eat? John Humphrys' book requires the full attention of anyone who cares about themselves or the future.
Download or read book Advancing Perioperative Practice written by Mark Radford and published by Nelson Thornes. This book was released on 2004 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the only textbook to cover the totallity of perioperative nursing, including infection control and risk management. Other areas of perioperative nursing not addressed in other texts are practice development, management, advanced practice and the roles of key team members. All three areas of the surgical experience are covered: pre-operative, intra-operative and post-operative care.
Download or read book The Challenge of Hospital Acquired Infection written by Karen Taylor and published by . This book was released on 2001 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title from the National Audit Office considers the combating of infections caught by patients while being treated in hospital. The Challenge of Hospital Acquired Infection highlights the issues about which all NHS employees must be aware in order to fight and reduce the severity of this problem.
Download or read book A Social History of Medicines in the Twentieth Century written by John Crellin and published by CRC Press. This book was released on 2020-08-13 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a fresh perspective on the day-to-day use of medicine! A Social History of Medicines in the Twentieth Century explores the most perplexing issues concerning the uses of prescriptions and other medicines on both sides of the Atlantic. The book equips you with a thorough understanding of the everyday use of medicine in the United States, Canada, and Britain, concentrating on its recent past. Dr. John K. Crellin, author of several influential books on the history of medicine and pharmacy, addresses vital topics such as: the emergence of prescription-only medicines; gate-keeping roles for pharmacists; the role of the drugstore; and the rise of alternative medicines. A Social History of Medicines in the Twentieth Century adds the historical perspective missing from most medical and pharmaceutical literature about trends in the day-to-day use of medicines in society. The book is essential reading for anyone taking regular medication, either as self-care or by a physician’s prescription. Topics discussed include the non-scientific factors that validate medicines, the relevance of the control of narcotics, marketing strategies used by the pharmaceutical industry, the changing authority of physicians and pharmacists, over-the-counter medicines, tonics and sedatives, and patient complianceand non-compliance. A Social History of Medicines in the Twentieth Century also addresses: medicines for weakness (health foods, fortifiers, digestives/laxatives) poison and pharmacy legislation placebos tranquilizers and antidepressants hormones side-effects psychoactive medications herbal medicines a brief history of the use of medicines from the 17th to 19th centuries suggestions for future policies and much more! A Social History of Medicines in the Twentieth Century is equally vital as a professional resource for physicians, pharmacists, and health care administrators, as a classroom guide for academics working in the medical and pharmaceutical fields, and as a resource for patients.
Download or read book The Resistance Phenomenon in Microbes and Infectious Disease Vectors written by Institute of Medicine and published by National Academies Press. This book was released on 2003-03-26 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.
Download or read book The Management and Control of Hospital Acquired Infection in Acute NHS Trusts in England written by Great Britain. National Audit Office and published by . This book was released on 2000 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management and Control of Hospital Acquired Infection in Acute NHS Trusts in England : Report: Session 1999-00
Download or read book Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine written by National Academies Of Sciences Engineeri and published by National Academies Press. This book was released on 2022-07-20 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Strategy for Combating Antibiotic Resistant Bacteria, published in 2014, sets out a plan for government work to mitigate the emergence and spread of resistant bacteria. Direction on the implementation of this strategy is provided in five-year national action plans, the first covering 2015 to 2020, and the second covering 2020 to 2025. Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine evaluates progress made against the national strategy. This report discusses ways to improve detection of resistant infections and estimate the risk to human health from environmental sources of resistance. In addition, the report considers the effect of agricultural practices on human and animal health and animal welfare and ways these practices could be improved, and advises on key drugs and diseases for which animal-specific test breakpoints are needed.
Download or read book Reducing healthcare associated infections in hospitals in England written by Great Britain: National Audit Office and published by The Stationery Office. This book was released on 2009-06-12 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Department of Health introduced a target to reduce MRSA across all NHS trusts by 50 per cent by 2008 and C. difficile by 30 per cent by 2010-11. MRSA had been reduced by 57 per cent by the end of March 2008 and C. difficile by 41 per cent. While a quarter of trusts have reduced MRSA by more than 80 per cent, in 12 per cent of trusts there has been an increase in MRSA infections. Twenty-nine per cent of trusts have reduced C. difficile by more than 50 per cent, but in 19 per cent of hospital trusts the numbers of C. difficile infections have increased. Since the introduction of the targets, the Department has spent some £120 million tackling healthcare associated infections. There have also been unquantifiable administrative costs and local expenditure on the drive to reduce infection rates. These initiatives have led to savings on treatment of between £141 million and £263 million, as well as reducing discomfort, disability and, for some, death that might have been caused by these avoidable infections. There has also been a perceptible change in trust leadership on tackling infections. The impact has not, however, been the same in all trusts or for other infections. Following the Department's intervention to improve recording on death certificates where MRSA or C. difficile was the underlying cause or a contributory factor, in 2007 around 9,000 people were reported as having died in such circumstances. There is still no national information on deaths from other healthcare associated infections such as urinary tract infections and pneumonia and blood stream infections due to other causes may be increasing.
Download or read book Antimicrobial Resistance written by Mihai Mares and published by BoD – Books on Demand. This book was released on 2021-03-03 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tackling the realities of the antimicrobial resistance (AMR) situation today is no longer uncommon. Many battles have been fought in the past since the discovery of antibiotics between man and microbes. In the tussle of new antibiotic modifications, the transmission of resistant genes, both vertically and horizontally unveils yet another resistant attribute for the microbe, for it only to be faced with a more powerful, wide spectrum antibiotic; the cycle continues-and the winner is yet to be known. This book aims to provide some insight into various molecular mechanisms, agricultural mitigation methods, and the One Health applications to maybe, just maybe, tip the scales towards us.
Download or read book Assisted Dying for the Terminally Ill Bill HL written by Great Britain: Parliament: House of Lords: Select Committee on the Assisted Dying for the Terminally Ill Bill and published by The Stationery Office. This book was released on 2005-04-28 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Bill was published as HLB 4, session 2004-05 (ISBN 01084188390). This volume contains a selection of the 14,000 personal letters and other submissions received by the Committee with regards to their inquiry into the Bill.
