Download or read book Delayed Cerebral Ischaemia Prevention and Treatment After Aneurysmal Subarachnoid Haemorrhage written by Michaël Veldeman and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prevention and Treatment of Delayed Ischaemic Dysfunction in Patients with Subarachnoid Haemorrhage written by Hans-Jürgen Reulen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last meeting of the European Association of Neurosurgical Societies (Barcelona 7-16 September 1987), a Symposium was devoted to the use of calcium antagonists in cerebral vasospasm. As shown by its title "Prevention and treatment of delayed ischaemic dysfunction in patients with subarachnoid haemorrhage: an update", papers presented at the Symposium covered a broad spectrum from some basic data on pathophysiology of subarachnoid haemorrhage (SAH) and delayed ischaemic dysfunction, to the clinical use of nimodipine, which has been largely documented among calcium inhibitors for its cerebrovascular properties. This supplementum of Acta Neurochirurgica is based upon the papers presented. Some articles, however, have been extended to take into account further results in order to present a broad view of the subject. The Symposium started with two presentations concerning general aspects of SAH: in the first one, B. Voldby reviewed the pathophysiological events following SAH: if modifications of intracranial pressure (ICP) and decrease of cerebral blood flow (CBF) are the primary alterations, metabolic changes (particularly reduction in CMR0 ) 2 contribute rapidly to disturbances of brain circulation. A variety of mechanisms may be responsible for the neurological dysfunction: most of them are directly related to the reduction in cerebral perfusion pressure (CPP) which may result in ischaemia. This fall in CPP (either due to elevation of ICP or reduction of mean arterial blood pressure) is observed under different pathophysiological conditions, discussed in the paper by A. D. Mendelow.
Download or read book Detection and Haemodilutive Treatment of Cerebral Arterial Vasospasm and Delayed Ischaemia After Aneurysmal Subarachnoid Haemorrhage written by Anders Ekelund and published by . This book was released on 1999 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cerebral Vasospasm Neurovascular Events After Subarachnoid Hemorrhage written by Mario Zuccarello and published by Springer Science & Business Media. This book was released on 2012-08-14 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book contains 48 articles presented at the 11th International Conference on Cerebral Vasospasm held in Cincinnati, Ohio, USA, in July 2011. This collection of papers represents a cross-section of the enormous progress that has been made towards a thorough understanding and effective treatment of neurovascular events following aneurysmal subarachnoid hemorrhage, including cerebral vasospasm. It is of interest to clinicians who wish to apply state-of-the-art knowledge to their management of this devastating condition and to basic scientists wishing to expand their understanding of cerebrovascular and neural pathophysiology related to subarachnoid hemorrhage.
Download or read book Inflammation and Delayed Cerebral Ischaemia Induced by Aneurysmal Subarachnoid Haemorrhage written by Catherine Jane McMahon and published by . This book was released on 2008 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Download or read book Pathogenesis Of Delayed Cerebral Ischemia In Aneurysmal Subanachroid Haemorrhage written by and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: INTRODUCTIONThe aneurysmal subarachnoid haemorrhage (aSAH) is a devastating form of a stroke. One of the most common complication after aSAH is the delayed cerebral ischemia (DCI), defined as focal or global neurological deterioration, cerebral infarction or both. The cerebral vasospasm has been suggested for a long time as the main reason of DCI, however the contribution of vessel narrowing in DCI remains unclear [1]. In order to study the pathogenesis behind DCI and determine the factors, which lead to cerebral ischemia, we used a multimodal continuous monitoring of multiple variables. METHODSA total of 40 patients with a mean age of 57u00b115 years with diagnosed moderate aSAH (Hu2013H grade 3u00b11) were prospectively enrolled in the study. Continuous recording of the arterial blood pressure (ABP), intracranial pressure (ICP), endu2013tidialCO2 (EtCO2), regional cerebral oxygenation (rSO2), cardiac output (CO), stroke volume variation (SVV) and cerebral blood flow velocity (CBFV) were performed using computeru2013based system Intensive Care Monitor (ICM+), Cambridge Enterprise. Cerebral autoregulation was assessed applying the pressure reactivity index (PRx), the tissue oxygenation index (TOx) and the mean velocity index (Mx).RESULTSIn analysed group of patients after aSAH 30% have DCI and 42% of them have also a vasospasm, which occurs in 5u00b12 day after onset. 75% of patients with DCI has cognitive or functional disorders. The systemic cardiovascular disorders (significant reduction in CO and ABP) during acute phase have been observed. The CO and SVV were stabilized due to apply a monitored therapy. The PRx on 3th day was significantly higher than on 6th day after onset (0.128 vs. -0.054, p=0.047). DISCUSSIONThe monitoredu2013guided agents therapy, combines with a multimodality monitoring of cerebral autoregulation, autonomic nervous system and cardiovascular system, allows to personalized treatment and better outcome in aSAH patients. This study was funded by the National Science Centre (Poland) under Grant No. 2013/09/B/NZ4/01343.REFERENCES[1.] Rowland MJ, Hadjipavlou G, Kelly M, Westbrook J, Pattinson KTS. Delayed cerebral ischaemia after subarachnoid haemorrhage: Looking beyond vasospasm. Vol. 109, British Journal of Anaesthesia. 2012. p. 315u201329.
Download or read book Contemporary Understanding and Management of Cerebral Vasospasm written by Ketan R Bulsara and published by JP Medical Ltd. This book was released on 2015-04-30 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vasospasm is the narrowing of the arteries in the brain following an aneurysm. It is one of the leading causes of death after a brain aneurysm. Contemporary Understanding and Management of Cerebral Vasospasm covers topics from recent advances in molecular mechanisms contributing to cerebral vasospasm, to practical microsurgical and endovascular treatment. Other topics include, the role of MRI in subarachnoid haemorrhage-related vasospasm and computed tomography, CT perfusion angiography correlated with digital subtracted angiography, and transcranial Doppler ultrasound imaging for detecting intracerebral arterial vasospasm. Contemporary Understanding and Management of Cerebral Vasospasm is essential reading for practitioners, including neurosurgeons, vascular specialists and neuroradiologists. Key Features Focuses on the latest advances in management of cerebral vasospasm 38 illustrations and images enhance explanations of latest developments in the field Edited by team of renowned US experts from Yale-New Haven Hospital, Connecticut
Download or read book Management of Subarachnoid Hemorrhage written by Adel E. Ahmed Ganaw and published by Springer Nature. This book was released on 2021-11-26 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on subarachnoid hemorrhage (SAH), describing in detail the neurophysiology, anatomy, epidemiology, grading, anesthesia management, coiling and interventional treatment of this dangerous disease. Written by leading international experts, it highlights the state-of-the-art techniques for the diagnosis and treatment (non-surgical and surgical) of SAH and the clinical variations. It also examines the reliability of the new techniques versus the standard clinical methods to predict problems related to SAH and its recent diagnosis and management. The book starts with a brief discussion of the epidemiology of SAH, cerebral circulation, anatomy of brain blood vessels and neurophysiology related to this fatal disease. Then, in the following chapters it covers grading of subarachnoid hemorrhage, anesthesia management of SAH, treatment, subarachnoid hemorrhage coiling and radiological intervention. Lastly, it explores surgical treatment of intracranial aneurysms in more detail, and addresses complications, critical care management and headache in SAH, traumatic SAH and prognosis. Featuring numerous images, tables, schema, illustrations and videos, the book is intended for junior and senior anesthesiologists, neuroscientists, intervention radiologists, intensivists and neurosurgeons.
Download or read book Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage written by Mervyn Driek Ingmar Vergouwen and published by . This book was released on 2009 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cerebral Haemodynamic Impairment written by Tnu Rtsep and published by LAP Lambert Academic Publishing. This book was released on 2009-11 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral vasospasm has been recognized as a cause of delayed cerebral ischaemia and as one of the adverse prognostic factors in patients with aneurysmal subarachnoid haemorrhage. As the risk of cerebral ischaemia is difficult to estimate by the severity of vasospasm alone, application of the concept of cerebral haemodynamic impairment might contribute to a better understanding of the pathogenesis of ischaemic brain damage after cerebral aneurysm rupture. This book describes clear associations between the haemodynamic factors and development of delayed cerebral ischaemia or an unfavourable clinical outcome. In patients with aneurysmal subarachnoid haemorrhage, close evaluation of haemodynamic impairment should be considered as an opportunity to identify the patients endangered by the development cerebral ischaemia due to vasospasm.
Download or read book Subarachnoid Haemorrhage written by M. Vermeulen and published by W.B. Saunders Company. This book was released on 1992 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is aimed at doctors who encounter difficulties in the diagnosis of subarachnoid haemorrhage and in the neurological and systematic complications which can arise in the management of such patients.
Download or read book Core Topics in Neuroanaesthesia and Neurointensive Care written by Basil F. Matta and published by Cambridge University Press. This book was released on 2011-10-13 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Core Topics in Neuroanesthesia and Neurointensive Care is an authoritative and practical clinical text that offers clear diagnostic and management guidance for a wide range of neuroanesthesia and neurocritical care problems. With coverage of every aspect of the discipline by outstanding world experts, this should be the first book to which practitioners turn for easily accessible and definitive advice. Initial sections cover relevant anatomy, physiology and pharmacology, intraoperative and critical care monitoring and neuroimaging. These are followed by detailed sections covering all aspects of neuroanesthesia and neurointensive care in both adult and pediatric patients. The final chapter discusses ethical and legal issues. Each chapter delivers a state-of-the art review of clinical practice, including outcome data when available. Enhanced throughout with numerous clinical photographs and line drawings, this practical and accessible text is key reading for trainee and consultant anesthetists and critical care specialists.
Download or read book The Stroke Book written by Michel T. Torbey and published by Cambridge University Press. This book was released on 2013-07-18 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential companion for busy professionals seeking to navigate stroke-related clinical situations successfully and make quick informed treatment decisions.
Download or read book Role of Eicosanoids in Delayed Cerebral Ischaemia Following Subarachnoid Haemorrhage written by Padraic O'Neill and published by . This book was released on 1988 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Evidence Based Management of Aneurysmal Subarachnoid Haemorrhage an Audit of Current Practice written by Sorana White and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence based management of aneurysmal subarachnoid haemorrhage an audit of current practiceWhite S.1, Heald M.2, Sunny S.2, Augustine A.2, Kakkar G.2Institute(s): 1Royal Wolverhampton NHS Trust, Dept of Anaesthesiology, Wol, United Kingdom, 2University Hospital North Midlands NHS Trust, Dept of Anaesthesiology, Stoke on Trent, United KingdomBackground and Goal of Study: Sub arachnoid haemorrhage (SAH) accounts for 5% of all stroke.Despite advances in diagnosis and treatment, overall mortality is around 50%. One-third of survivors are dependent for care and almost half will have cognitive impairment sufficient to affect their quality of life.A multidisciplinary team is involved in patient care and Anaesthetists are involved from the initial stabilization and diagnosis through to providing anaesthesia for definitive treatment and post operative support in critical care. Materials and methods: We conducted a retrospective audit of paper and electronic records looking at 21 patients who underwent coiling for SAH. The data was collected against the guidelines produced by AHA/ASA 2012 directed towards prevention and treatment of re-bleeding, vasospasm, delayed cerebral ischaemia, hydrocephalus and seizures, to assess current practice at University Hospital North Midlands, UK.Results and discussion: 21 patients (19 females and 2 male), age range 25 to 67 years old, mean 54.5 +/- 11.3. One third of aneurysms were multiple and two thirds were single. 15 aneurysms were less than 7mm in size. 52% of patients were transferred from another hospital.75% patients were treated within 24hrs 90% of patients treated within 48 hours. Mean time to treatment was 19 hours. 100% had nimodipine prescribed and 100% received nimodipine 38% of patients missed between 2 and 4 doses of nimodipine 33% of patients received 1st nimodipine dose in hospital >4 hours post admission 1/21 patients received tranexamic acid. 50% of patients had a 0 or 1 Modified ranking Scale score at 6 months follow up.Retrospective collection of data is flawed, but future audit will be improved following introduction of prospectively compiled database.Pre-operatively patients were managed appropriately as evidenced from good outcomes at 6 months. Improvements could be made in administration of prescribed drugs, in particularly nimodipine for which there is strong evidence for prevention of vasospasm.Optimal fluid balance and closer blood pressure control can also be improved to avoid secondary brain injury.Conclusion(s): Good practice was observed at UHNM complying with the recommendations of the AHA/ASA for definitive treatment of aneurysm within 72hrs. We are introducing a check-list style proforma with key interventions to be signed and dated in front of patient notes to improve and standardise care.
Download or read book Gupta and Gelb s Essentials of Neuroanesthesia and Neurointensive Care written by Arun Gupta and published by Cambridge University Press. This book was released on 2018-06-21 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition presents core clinical neuroanesthesia and neurointensive care knowledge in a practical, user-friendly format.
