Download or read book Endometrial Cytology with Tissue Correlations written by John A. Maksem and published by Springer Science & Business Media. This book was released on 2009-04-09 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: As compared with cytology’s use in other organ systems, direct cytological examination of the endometrium is not a widely practiced diagnostic procedure. This is an anomaly, because the endometrium is exceedingly available for cytological sampling, cytological sampling is comparably simple to perform, and, from the patient’s perspective, it is a gentle procedure as compared to other methods of specimen attainment. Over the years, as we personally gained more and more experience with specimen acquisition, processing and interpretation, we have come to look upon endometrial cytology as an effective method for ensuring endometrial normalcy and discovering and diagnosing malignant and premalignant states. In comparing endometrial cytology to endometrial biopsy, we have found that, in samples obtained by individuals experienced in specimen collection, cytology outperforms outpatient biopsy with regard to the patient’s tolerance of the procedure, adequacy of sampling among postmenopausal women, and detection of occult neoplasms. By devising a highly effective technical strategy to ensure the simultaneous creation of cell blocks and cytological samples from a single collection (that is detailed in the technical appendix of this work), we have moved endometrial brush collection into an arena of significance equaling—indeed exceeding—other methods of specimen collection and interpretation. Cytology, even in the absence of cell blocks, performs equally as well as biopsy in detecting outspoken hyperplasia or carcinoma. If nothing else, by reliably identifying benign, normal endometrial states, it serves to exclude more than 70% of women from unnecessary follow up testing with a high degree of confidence. Because brush sampling of the endometrium is limited to a depth of 1.5 to 2 mm, the method is not definitive for the detection of endometrial polyps, fibroids, stromal tumors, or tumors of the uterine wall musculature. However, endometrial cytology is useful for detecting benign estrogen-excess states such as disordered proliferation and various degrees of benign hyperplasia, for separating these states from frankly neoplastic states such as EIN and cancer, but not for subclassifying benign hyperplastic states in the absence of cell block preparations. When endometrial brushing with liquid fixation is used in conjunction with other techniques such as immunohistochemistry, concomitant biopsy or, more practically, hysteroscopy or sonohysterography, endometrial benignancy can be assured with a very high level of confidence (> 99%); indeed, manufacturing concomitant cell blocks of endometrial tissue fragments and using immunohistochemistry in selected cases significantly enhances the diagnostic specificity of the technique. In a woman with a patent cervix, endometrial brushing successfully collects material, even from late postmenopausal atrophic endometrium. It allows for the detection of serious diseases such as endometrial intraepithelial carcinoma under conditions where suction biopsy might miss or otherwise obviate the diagnosis. This work focuses on the background, collection technique, and reliability of endometrial cytology; it then overviews diagnostic criteria and diagnostic pitfalls encountered in the day-to-day practice of the art. Since endometrial cytology interpretation relies on intuiting tissue patterns from cytology preparations, a great deal of time is spent on cytohistological correlations and, where effective as part of a diagnostic strategy, on ancillary immunohistochemical staining. The discussion moves from normal states of the endometrium, through otherwise benign changes induced by an altered hormonal milieu or surface irritants, into neoplastic premalignant and malignant endometrial conditions. Finally, fixative and slide preparation techniques, that we deem as expeditious while serving to get the most information out of an endometrial cytology collection, are discussed in detail for the benefit of those who wish to recapitulate our work in their own practice.

Download or read book Cytopathology of the Endometrium written by Yijing Shu and published by . This book was released on 1992 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Yokohama System for Reporting Endometrial Cytology written by Yasuo Hirai and published by Springer Nature. This book was released on 2022-01-03 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes a standardized method for classifying and reporting invasive endometrial malignancies via direct endometrial sampling. Featuring a wealth of color illustrations, it provides specific diagnostic categories and cytomorphologic criteria to promote uniform and reliable diagnoses. It also describes the history of directly sampled endometrial cytology, reviews the sampling techniques and algorithmic approach, discusses specimen adequacy, and outlines challenges for the future. The Yokohama System for Reporting Endometrial Cytology – Definitions, Criteria and Explanatory Notes offers a valuable resource for researchers at clinical cytopathological laboratories around the world whose work involves gynecological cytology, oncology, pathology, and cytopathology. It will also appeal to researchers in the fields of cytotechnology, basic science, pathology and related industries, medical residents and clinicians.

Download or read book Cytopathology of the Endometrium written by Liang-Che Tao and published by . This book was released on 1993 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Histopathology of the Endometrium written by Gisela Dallenbach-Hellweg and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endometrium differs from all other tissues of the body in that it rhythmically changes its structure and function. For many years the meaning of these changes remained puzzling and obscure. At about the turn of the century some investi gators held the physiological fluctuations of the menstrual cycle to be inflamma tory changes. Later, when stricter criteria for the pathology of the endometrium were applied, morphologists misinterpreted pathological fluctuations in the cycle either as physiological variations, or they overlooked them entirely. Today as previously the pathologist is often confronted with the dilemma that he is unable to adequately diagnose the endometrium merely from the structural changes. Accordingly, the gynecologist finds the pathological report of little value. In like manner, if the clinical information given the pathologist is incomplete, then he cannot form a clear notion of the clinical problem. Although the detection of focal lesions of the endometrium is important, of much greater consequence is the recognition of functional (hormonally controlled) variations and their cyclic course, for it is from these that the clinician is guided in deciding what therapy he should use. The ability to detect such functional changes requires not only that the morphologist possess a thorough knowledge of the physiological and pathological anatomy of the endometrium but also that he receive exact information about the patient's menstrual history and have in sight into clinical problems.

Download or read book Equine Hematology Cytology and Clinical Chemistry written by Raquel M. Walton and published by John Wiley & Sons. This book was released on 2020-11-04 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The all-new Equine Hematology, Cytology, and Clinical Chemistry draws on hematology and clinical chemistry information featured in the first edition of Equine Clinical Pathology and adds valuable cytopathology material from Diagnostic Cytology and Hematology of the Horse, making it a truly definitive reference to clinical pathology in equids. Thoroughly updated and expanded throughout, this Second Edition offers more images, more information, and new knowledge for previous chapters and entirely new chapters on bone marrow evaluation and cytopathology. Designed to present clear, concise, and clinically relevant information, the book is logically organized for easy reference. Numerous figures, tables and images support the text, together with summarized information for ease of use. Offers a focus on clinical pathology in the horse, with in-depth information on hematology, clinical chemistry, and cytopathology in equids Presents equine disease from a systems-based, clinicopathological perspective Features hundreds of high-quality images Includes contributions from veterinary specialists with expert knowledge of clinical pathology A must-have purchase for anyone using hematology, clinical chemistry, and cytology in equine patients, Equine Hematology, Cytology, and Clinical Chemistry, 2nd Edition is a valuable resource for equine practitioners, clinical pathologists and residents, and veterinary students.

Download or read book Cytopathology of the Glandular Lesions of the Female Genital Tract written by Matías Jiménez-Ayala and published by Karger Medical and Scientific Publishers. This book was released on 2011 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: This outstanding monograph presents a detailed description of cytopathological lesions of the female genital tract. Twelve international experts in the cytopathology of glandular lesions cover the complete spectrum of this challenging subject. Genital glandular lesions, both benign and malignant, are an appealing field of cytopathology. Malignant lesions of the endocervix and endometrium are becoming more common all over the world, compared to squamous cell carcinoma. In situ and invasive endocervical adenocarcinoma, endometrial adenocarcinoma and endometrial hyperplasias are presented in this book. Additionally ovarian lesions focusing data obtained from detailed intraoperative studies and other areas of the genital tract, such as the vulva and fallopian tube, which are less known and thus have seen fewer publications, are also shown. The impact of the Bethesda System, as well as basic and ancillary techniques in the study of glandular lesions complete the monograph. This book will be of great use to cytopathologists, pathologists and cytotechnologists and to students of these specialities as it deals with the most common areas of their daily work.

Download or read book Veterinary Cytology written by Leslie C. Sharkey and published by John Wiley & Sons. This book was released on 2020-08-04 with total page 1024 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a state-of-the-art, evidence-based reference to all aspects of veterinary cytology. Truly multidisciplinary in its approach, chapters are written by experts in fields ranging from clinical pathology to internal medicine, surgery, ophthalmology, and dermatology, drawing the various specialties together to create a comprehensive picture of cytology's role in diagnosis and treatment of animal disease. Firmly grounded in the primary literature, the book focuses on companion animals, with special chapters for species with fewer publications. Chapters are logically organized by body system, with additional chapters on tumors of particular import and diagnostic decision making. The first two sections of Veterinary Cytology focus on cytology techniques, quality control, and special laboratory techniques. Subsequent sections are organ/tissue-based and reflect what is known about the canine, feline, and equine species. This is followed by chapters on non-traditional species, including exotic companion mammals, rabbits, cattle, camelids, non-human primates, reptiles and birds, amphibians, fish, invertebrates, and sheep and goats. The last section highlights some unique features of the applications of cytology in industry settings. Provides a gold-standard reference to data-driven information about cytologic analysis in companion animal species Brings together authors from a wide range of specialties to present a thorough survey of cytology's use in veterinary medicine Offers broader species coverage and greater depth than any cytology reference currently available Veterinary Cytology is an essential resource for clinical and anatomic pathologists and any specialist in areas using cytology, including veterinary oncologists, criticalists, surgeons, ophthalmologists, dermatologists, and internists.

Download or read book Cytopathology of the Endometrium written by Yi-Jing Shu and published by McGraw-Hill Companies. This book was released on 1992-01-01 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Glandular Lesions of the Uterine Cervix written by Rosemary H. Tambouret and published by Springer. This book was released on 2014-11-05 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a compact, concise and up-to-date resource for pathologists and clinicians who are involved in women’s health. The book summarizes the incidence, epidemiology and risk factors for cervical adenocarcinoma, while reviewing the normal histology of the cervix and glandular lesions of the cervix. The cytological appearance of glandular lesions of the cervix and their mimics is amply illustrated and discussed. Management of glandular lesions is also outlined. Written by authorities in the field, Glandular Lesions of the Uterine Cervix: Cytopathology with Histologic Correlates is of great value to cytopathologists, surgical pathologists, gynecologic oncologists and surgeons.

Download or read book Modern Uterine Cytopathology written by Alexander Meisels and published by . This book was released on 2007-01-01 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Uterine Cytopathology: Moving to the Molecular Smear sets out to be the reference guide that bridges gaps between cytomorphology, molecular biology, and molecular technologies in the diagnostic cytology service. Increasingly, conventional cytology intersects with new technologies based on the link of cervical cancer and human papillomaviruses (HPV). Dr. Meisels and his co-authors/contributors build upon their decades of experience, providing heavily imaged chapters devoted to cytomorphology of infection and benign changes, squamous intraepithelial lesions, glandular lesions, hormonal cytology, and rare lesions of the uterus. Most chapters in Modern Uterine Cytopathology offer practical, working understandings of new and emerging approaches to diagnosis and prevention: prevention of uterine cancers, epidemiology, human papillomaviruses, cervical carcinogenesis, biomarkers for screening, HPV vaccines, LBC imagers and screeners, and technical considerations for molecular and serologic diagnosis. Expert contributors from both North America and Europe bring an international perspective to the evolving practice of cytopathology in a molecular age.

Download or read book Atlas of Endometrial Histopathology written by Gisela Dallenbach-Hellweg and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: For this second, expanded edition, most of the chapters have been extensively revised to include the latest immunohistochemical and molecular biological methods. With its clearly thought-out structure, this atlas enables the pathologist to find, classify, and differentially diagnose each disease. 280 top-quality illustrations - over half in full colour - are each accompanied by a description of the pathology of the disease, a summary of the causes, an explanation of its clinical importance, and treatment options, emphasising the importance of constant mutual co-operation with the attending gynaecologist. Microphotographs are arranged systematically according to morphology, and each is followed by a short description together with the aetiology and morphologic and differential diagnosis of the different conditions. Hemming Poulsen is head of the WHO Collaborating Center for the Histological Classification of tumours and the new chapter on neoplasms, for example, reflects this new WHO classification. Additional chapters cover gestational diseases as well as new findings in infertility and hormone replacement therapy.

Download or read book Endometrial Adenocarcinoma written by Matías Jiménez-Ayala and published by Karger Medical and Scientific Publishers. This book was released on 2008-01-01 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: A color cytology atlas of the most common malignant tumor of the female genital tract The incidence of endometrial adenocarcinoma, the most common malignant tumor of the female genital tract in developed countries, has increased over recent years. A variety of collection techniques are available to obtain cytologic or histopathologic samples for its diagnosis but their interpretation can be difficult without proper collection and preparation. However, this monograph, written by internationally recognized experts, is a most valuable educational resource for the pathologist and cytopathologist in the techniques of endometrial sampling and diagnosis. The chapters are comprehensive and logically organized, covering the epidemiology and pathogenesis of endometrial adenocarcinoma, endometrial sampling techniques and the spectrum of cytomorphologic appearance from benign through hyperplasia to adenocarcinoma of the endometrium. A separate chapter covers non-epithelial uterine malignancies. Throughout the monograph, inclusion of both cytologic and H&E histologic images allows cytohistologic correlation of lesions. In summary, this endometrial handbook seeks to clarify a difficult area of cytodiagnosis and will become an important reference text for cytopathologists, pathologists and cytotechnologists.

Download or read book Silverberg s Principles and Practice of Surgical Pathology and Cytopathology 4 Volume Set with Online Access written by Mark R. Wick and published by Cambridge University Press. This book was released on 2015-03-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Silverberg's Principles and Practice of Surgical Pathology and Cytopathology is one of the most durable reference texts in pathology. Thoroughly revised and updated, this state-of-the-art new edition encompasses the entire fields of surgical pathology and cytopathology in a single source. Its practice-oriented format uniquely integrates these disciplines to present all the relevant features of a particular lesion, side by side. Over 4000 color images depict clinical features, morphological attributes, histochemical and immunohistochemical findings, and molecular characteristics of all lesions included. This edition features new highly experienced and academically accomplished editors, while chapters are written by the leading experts in the field (several new to this edition, bringing a fresh approach). Dr Steven Silverberg's practical approach to problem solving has been carefully preserved. The print book is packaged with access to a secure, electronic copy of the book, providing quick and easy access to its wealth of text and images.

Download or read book Atlas of Endometrial Histopathology written by Gisela Dallenbach-Hellweg and published by Springer Science & Business Media. This book was released on 2010-04-23 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition differs from the preceding ones in that there has been extensive revision of most chapters. Recent advances in research gained by immunohistochemical, molecular biological, and cytogenetic methods are included, as far as they are applicable for daily diagnostic work. The chapter on neoplasms, in particular, has been greatly expanded in accordance with the new WHO International Histological Classification of genital tract tumors, covering all pertinent differential diagnostic aspects. The chapter on malignant lymphomas and hematopoetic neoplasms involving the endometrium is a new contribution to this edition (F. D. , Ulm). We have revised the chapter on gestational diseases, incorpor- ing recent advances in the differential diagnosis of gestational trophoblastic tumors. New discoveries and experiences in correlating structure and function in infertility and in h- mone replacement therapy of peri- and postmenopausal patients are also included. Many new microphotographs have been added to illustrate the advances in tumor research and in immunohistochemical detection methods. We have updated the list of references including recent relevant publications. To the correspondents and consultants who have contributed valuable observations and suggestions, bringing thereby to our attention omissions in the second edition, we acknowledge our cordial thanks. We thank Dr. Wolfram Klapper, Director of the L- phom Register of the University of Kiel, for case material for making the micropho- graphic illustrations of lymphomas. The staff of Springer-Verlag has earned our gratitude for their skill in preparing this new edition.

Download or read book Uterine Pathology written by Robert A. Soslow and published by Cambridge University Press. This book was released on 2012-05-31 with total page 877 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Cambridge Illustrated Surgical Pathology series, this book provides a comprehensive account of the experienced gynecologic pathologists' diagnostic approach to uterine pathology. Discussion is built around major pathologic entities in the uterus and cervix while highlighting the diverse and complex spectrum of alterations encountered in daily practice. Emphasizing clear description, diagnostic algorithms and problem solving, the book's primary goal is to lay the foundation for diagnostic accuracy, reproducibility, and relevance. It also dispels common misconceptions and encourages an intelligent and thoughtful approach to diagnostic problems using all the tools available to the modern physician. The book is richly illustrated, with more than 700 color photomicrographs, all of which are also found in downloadable format on the accompanying CD-ROM.

Download or read book Cytopathology of the Uterus written by Alexander Meisels and published by American Society of Clinical Pathologists Press. This book was released on 1997 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: