Download or read book Cytopathology in Oncology written by Ritu Nayar and published by Springer Science & Business Media. This book was released on 2013-10-04 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent decades, cytopathology has assumed an increasing role in the primary diagnosis of mass lesions owing to its ability to deliver rapid, non-invasive, and timely information. This book provides a comprehensive overview of the role of cytology at various body sites. The diagnostic details covered are abbreviated in comparison with those in pathology texts. Instead, a more clinical approach is taken, with the focus on the advantages and limitations of techniques and the key features of entities that are important to clinicians. Pathological–clinical correlation is highlighted throughout the book, ensuring that it will be highly relevant for clinicians. In particular, physicians who deal with oncology patients will find it to be a rich source of guidance on how to use and understand cytopathology in the diagnosis and exclusion of malignancy.

Download or read book Molecular Cytopathology written by Bin Yang and published by Springer. This book was released on 2016-08-12 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the current applications of molecular tools in cytopathology and provides a concise handbook for those who provide care in this era of personalized medicine. Specifically, the text provides a comprehensive and concise review of the emerging molecular tests available clinically in different subspecialities of diagnostic pathology. It reviews the current data of molecular testing already applied in cytopathology, discusses some of the biomarkers with potential utility in cytopathology in the near future and reviews the technical challenges in applying and validating molecular tools in liquid-based cytologic materials. Molecular Cytopathology will serve as a valuable resource for cytopathologists, cytotechnologists, pathology trainees, and clinicians with an interest in molecular applications in cytopathology.

Download or read book Diagnostic Pathology Molecular Oncology E Book written by Mohammad A Vasef and published by Elsevier Health Sciences. This book was released on 2019-08-08 with total page 1000 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering all aspects of molecular pathology as it relates to the transformation and pathogenesis of cancer, this award-winning volume in the Diagnostic Pathology series is an expert resource for pathologists at all levels of experience and training, both as a quick reference and as an efficient review to improve knowledge and skills. This easily accessible, point-of-care reference features templated, bulleted content that is generously illustrated with charts, graphs, tables, and color photomicrographs of histology with special stains. It offers a practical, clinical approach to examining how molecular mutations affect common medical diseases and identifies the relevant and appropriate molecular tests to perform for a complete work-up in the era of molecular-targeted therapies. Provides updated information on molecular mutations in different tumors, including solid tumors and hematopoietic neoplasms, and new targeted therapies geared toward these molecular alterations Discusses now widely used immunotherapy treatments, including how immunotherapy has revolutionized the treatment of many neoplasms such as breast and lung carcinomas and lymphoma Features more than 2,000 annotated images throughout, including H&E stains, immunostains, and FISH images Covers timely topics such as: Recent advances in cancer immunotherapy, specifically in the molecular basis of immunotherapy Newly discovered targeted therapies, including multiple lung carcinoma therapies now considered for patients based on existing mutations to specific genes (KRAS, ALK, BRAF, and ROS) The need for integration of myeloid and lymphoid gene panels due to increased knowledge from next generation sequencing studies of new mutations and the resulting newly developed molecular targets Increased usage of next generation sequencing techniques Changes to hematopoietic tumor details based on revised WHO guidelines Recipient of a 2016 BMA Award: Highly Commended, Pathology (previous edition)

Download or read book Cytopathology An Issue of Surgical Pathology Clinics written by Vickie Jo and published by Elsevier Health Sciences. This book was released on 2018-09-07 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Surgical Pathology Clinics, edited by Dr. Vickie Jo, focused on Cytopathology. Topics include--but are not limited to--Head and Neck Cytology: HPV-Associated Carcinomas; Updates in Thyroid Cytology; Salivary Gland Cytopathology; Pulmonary Cytopathology; Updates in Effusion Cytology; Updates in Gynecologic Cytology; Diagnostic Advances in Urine Cytology; Renal Neoplasms; Pancreaticobiliary Cytology; Carcinoma of Unknown Primary; Soft Tissue Neoplasms; Primary Bone Tumors; Pediatric Cytopathology; Advances in Molecular Testing Techniques in Cytological Specimens; and Circulating Tumor Cells: Applications in Cytopathology.

Download or read book Modern Techniques in Cytopathology written by M.M. Bui and published by Karger Medical and Scientific Publishers. This book was released on 2020-01-13 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the era of precision medicine, physicians are increasingly in need of more definitive diagnostic, prognostic, and predictive information derived from small biopsy specimens such as cytology samples in order to guide effective patient care. Cytopathology is well poised to meet this challenge. Whilst the traditional cytomorphologic component of cytology practice is still valid, enormous advances have been made in the field of cytopathology thanks to transformative technology and innovative individuals that have augmented the cytologists' ability to meet the demands of modern medicine. The purpose of this book is to describe, illustrate, and review many of the most recent developments regarding modern techniques employed in cytopathology. This latest monograph is intended for all cytologists including cytopathologists, cytotechnologists, cytology lab assistants, trainees, research scientists, and anyone who is interested in the field of cytopathology. We have invited pioneering experts in their respective fields to author these chapters. This book is not only the culmination of their groundbreaking work and effort but also presents a critical review of the current literature. We have attempted to provide readers with an informative and comprehensive aid so that they may better appreciate how emerging technology has been applied to cytology. Each chapter in this book presents a stand-alone contemporary review of emerging topics in cytopathology. We hope that you will find this monograph thought-provoking and a valuable reference for your practice.

Download or read book Effusion Cytology written by Parvin Ganjei-Azar, MD and published by Demos Medical Publishing. This book was released on 2011-02-22 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, cytology of body cavity fluids is an integral part of cancer staging. A positive diagnosis indicates a high-stage (III or IV) cancer in a majority of instances. General pathologists and cytotechnologists rely on routine cytomorphologic criteria to help oncologists in their staging of cancer patients. The diagnostic clarity, however, is challenged by many false negatives and occasional false positive results. The former is usually followed by an unnecessary surgical procedure in the case of an under-staged cancer and the latter may prevent treatment of a potentially curable disease due to a falsely up-staged cancer. Effusion Cytology is a practical manual in diagnosis and interpretation of body cavity fluid (BCF) specimens. This highly illustrated volume will provide handy information for the residents, fellows and general pathologists with limited basic knowledge in the area of cytopathology. The book provides a step-by-step guide to evaluation of BCF specimens with the specific goal of identification of malignancies. Use of ancillary techniques such as immunocytochemistry is discussed where appropriate. Special attention is given to the formulation of final cytologic reports of the diagnosis of difficult cases. Features of Effusion Cytology Include: Focus on Cancer Diagnosis: The book seeks to answer the simple question - Does this fluid represent malignancy? Practicality: Offers practical approaches to resolving the numerous daily technical and diagnostic problems encountered in a cytology laboratory dealing with body cavity fluid specimens Use of Limited Panel of Tumor Markers by Immunocytochemistry (ICC): Describes a simple innovative technique for applying ICC to cytologic smears A Practical Guide to Formulate Final Cytologic Reports: The reader will be guided as to how to convey any diagnostic difficulty or issue to the attending physician

Download or read book Cytology Pathology and Cancer Prognosis written by Károly Lapis and published by . This book was released on 1987 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Paris System for Reporting Urinary Cytology written by Eva M. Wojcik and published by Springer Nature. This book was released on 2022-02-03 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of The Paris System for Reporting Urinary Cytology introduced a completely new paradigm for detecting bladder cancer by urine cytology. This system concentrated on defining morphological characteristics of the most clinically significant form of bladder cancer, High Grade Urothelial Carcinoma. This new approach has been widely accepted throughout the world, and has become part of the daily practice of cytology. Considering that the first edition of The Paris System (TPS) introduced a new model of urinary cytodiagnosis, verification and expansion of initial material and data were anticipated. Based on evolving knowledge and readership requests, the group of highly experienced authors have created a new edition of TPS. This second edition includes areas and issues not originally covered. A new chapter on urine cytology of the upper tract, a rarely addressed topic, has been introduced. Furthermore, the issue of cellular degeneration is discussed in the criteria of all diagnostic categories. Examples of standardized reports are included in each chapter. Most importantly, a separate chapter presents data defining the risk of malignancy (ROM) for each diagnostic category to inform clinical management. New high quality images augment those of the first edition to better illustrate diagnostic clues and potential pitfalls. In addition to chapters on diagnostic criteria, current concepts of pathogenesis of bladder cancer, specimen adequacy and preparation, and ancillary tests are covered in separate chapters. A bonus to the volume is a comprehensive history of urine as the earliest diagnostic sample of human disease, richly illustrated with artworks from major museums. Written by internationally recognized authorities, this comprehensive and evidence-based guide to urine cytology is supported by the newest data confirming the original concept and significance of diagnostic criteria defining High Grade Urothelial Carcinoma. TPS is an essential tool for anyone who is practicing urinary cytology, including cytotechnologists, pathologists-in-training and practicing pathologists. This book should find a place in every cytology laboratory throughout the world. The Concept has been endorsed by the American Society of Cytopathology, and the International Academy of Cytology.

Download or read book Diagnosing Non small Cell Carcinoma in Small Biopsy and Cytology written by Andre Luis Moreira and published by Springer. This book was released on 2014-10-07 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a practical yet comprehensive guide to manage the shift in the diagnosis of lung cancer from large resections to small samples, including cytology specimens and core biopsies. Specifically, it outlines various available minimally-invasive modalities and presents algorithms to optimize and maximize sample collection and processing beginning at the time of tissue acquisition during the procedure. Secondly, the book provides an overview of the various existing and emerging lung cancer therapies and why a specific diagnosis is crucial. Key elements for the classification of small biopsies and cytology proposed by the ATS, IASLC, and ERS are highlighted. A section dedicated to immunohistochemistry offers a logical, step-by-step guide to sub-classify lung cancers and to differentiate them from metastases. The text also provides a review of the various molecular tests (and alternatives in cases of scant tissue) required for lung adenocarcinomas. Finally, potential pitfalls to avoid during acquisition, processing, and classification are discussed. With contributions from a team of multidisciplinary authors who are regularly involved in the care of lung cancer patients , Diagnosing Non-small Cell Carcinoma in Small Biopsy and Cytology is an invaluable reference guide for pathologists, pathologists-in-training, and allied professionals, including oncologists, pulmonologists, surgeons, and radiologists. ​

Download or read book The Milan System for Reporting Salivary Gland Cytopathology written by William C. Faquin and published by Springer Nature. This book was released on 2023-06-26 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Second Edition of The Milan System for Reporting Salivary Gland Cytopathology, like the First Edition, represents a collaborative effort by a multidisciplinary group of cytopathologists, surgical pathologists, molecular pathologists, radiologists, and head and neck surgeons. This international group shares the goal of creating a practical and uniform reporting system for salivary gland fine needle aspiration (FNA). This book is organized into six general diagnostic categories: “Non-Diagnostic,” “Non-Neoplastic,” “Atypia of Undetermined Significance (AUS),” “Neoplasm: Benign,” “Neoplasm: Salivary Gland Neoplasm of Uncertain Malignant Potential (SUMP),” “Suspicious for Malignancy,” and “Malignant.” It includes definitions, morphologic criteria, and explanations for each of the diagnostic categories. Specific chapters are dedicated to the application of the latest available ancillary studies, radiologic features of salivary gland lesions, clinical management, and histological considerations including updates from the most recent 5th Edition WHO blue book. The Milan System for Reporting Salivary Gland Cytopathology 2nd Edition represents an essential step towards increasing the overall effectiveness of salivary gland FNA and fostering better communication between clinicians and between institutions to improve overall patient care.

Download or read book Practical Oncologic Molecular Pathology written by Yi Ding and published by Springer Nature. This book was released on 2021-07-10 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a review and high-yield reference on the clinical molecular diagnostics of malignant neoplasms. It aims to address the practical questions frequently encountered in the molecular oncology practice, as well as key points and pitfalls in the clinical interpretation of molecular tests in guiding precision cancer management. The text uses a Q&A format and case presentations, with emphasis on understanding the molecular test methods, diagnosis, classification, risk assessment and clinical correlation. Starting with an update on the molecular biology of cancer, the book focuses on the topics related to molecular diagnostics and genetics-based precision oncology. Separate chapters are dedicated to discussion of the bioinformatics for the analysis of genetic/genomic data generated from molecular assays, and quality control (QC)/quality assurance (QA) programs in the clinical laboratories; both are critical in producing high quality results for clinical care of cancer patients. These are followed by organ system-based reviews and discussions on the molecular genetic abnormalities and related tests covering diverse types of common to rare malignant neoplasms. This book also provides up-to-date knowledge related to malignant neoplasms, discusses the established as well as evolving requirements for pathologic diagnosis of these malignancies. It also discusses the cost effective utilization of molecular tests in clinical oncology. Written by experts in the field, Practical Oncologic Molecular Pathology serves as a valuable reference for practicing pathologists, fellows, residents and other health care professionals.

Download or read book Diagnostic Pathology Molecular Oncology E Book written by Mohammad A. Vasef and published by Elsevier Health Sciences. This book was released on 2023-12-04 with total page 1050 pages. Available in PDF, EPUB and Kindle. Book excerpt: This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Providing a clear understanding of molecular pathology as it relates to the transformation and pathogenesis of cancer in an era of personalized medicine, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Molecular Oncology is a visually stunning, one-stop resource for every practicing pathologist, hematopathologist, molecular pathologist, oncologist, or pathologist in training as an ideal day-to-day reference or as a reliable learning resource. Provides up-to-date, comprehensive coverage of relevant molecular tests and their clinical applications, along with organ-based chapters on the molecular genetic data relevant to individual disease entities Contains new chapters and substantial revisions to existing content that include updates from the 2022 International Consensus Classification and the WHO Classification of Haematolymphoid Tumours, fifth edition Provides expert guidance on selecting the right test(s) at the right time, as well as comparisons of molecular testing methods (e.g., FISH vs. cytogenetics) Includes current information for new actionable mutations and targeted therapies Covers ultrasensitive molecular techniques for minimal residual disease detection and disease monitoring Discusses circulating cell-free DNA analysis for detection of resistance-associated mutations and disease monitoring, and provides usage details Features an image-rich layout with more than 2,400 print and online-only images, including high-resolution H&E stains, immunostains, FISH images, gross pathology and clinical photographs, detailed full-color medical illustrations, and informative diagrams, charts, and schematics Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert reference at the point of care Any additional digital ancillary content may publish up to 6 weeks following the publication date Molecular oncology is a rapidly evolving field with tremendous amounts of information that is new since the 2e published in March 2019. There is new molecular genetic data linked to either new targeted therapies or that serves as diagnostic or prognostic indicators. The 3e will include 8-10 new chapters and substantial updates and rewrites to existing contents to make sure ongoing edits and revisions to the upcoming WHO Classification of Hematopoietic Tumors are included in the 3e. The authors provide guidance on selecting the right test(s) at the right time for the right patient and comparisons of molecular testing methods (i.e., FSH testing vs. cytogenetics) are included. The market lacks a definitive source of all the recent changes, and DP3 Molecular Oncology will provide a comprehensive information source.

Download or read book The Papanicolaou Society of Cytopathology System for Reporting Respiratory Cytology written by Lester J. Layfield and published by Springer. This book was released on 2018-11-22 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents comprehensive review of the recommendations of the Papanicolaou Society of Cytopathology for reporting results of respiratory cytology specimens along with advances in diagnostic, prognostic, and predictive immunohistochemical and molecular techniques which can be performed on cytology specimens.The majority of the text focuses on the standardized terminology and nomenclature for respiratory cytology as recommended by the Papanicolaou Society of Cytopathology. Each of the diagnostic categories are described in depth and formal definitions for each category are given along with cytologic criteria. Explanatory notes are given discussing limitations of the category as well as its malignancy risk and reproducibility. Management recommendations are supplied for each category. Sample reports documenting the preferred reporting format are also given. Each category is associated with a reference list establishing the evidence based nature of the categories. An in depth discussion of ancillary testing is provided, including the utilization of microbiologic culture, immunohistochemistry, and molecular techniques. Substantial emphasis is placed on molecular diagnostics necessary for optimization of personalized testing and the appropriate use of targeted therapies. The text represents a comprehensive resource for the state of the science of the cytologic diagnosis of respiratory lesions.

Download or read book Molecular Pathology of Lung Cancer written by Philip T. Cagle and published by Springer Science & Business Media. This book was released on 2012-06-14 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: As with other books in the Molecular Pathology Library Series, Molecular Pathology of Lung Cancer bridges the gap between the molecular specialist and the clinical practitioner, including the surgical pathologist who now has a key role in decisions regarding molecular targeted therapy for lung cancer. Molecular Pathology of Lung Cancer provides the latest information and current insights into the molecular basis for lung cancer, including precursor and preinvasive lesions, molecular diagnosis, molecular targeted therapy, molecular prognosis, molecular radiology and related fields for lung cancer generally and for the specific cell types. As many fundamental concepts about lung cancer have undergone revision in only the past few years, this book will likely be the first to comprehensively cover the new molecular pathology of lung cancer. It provides a foundation in this field for pathologists, medical oncologists, radiation oncologists, thoracic surgeons, thoracic radiologists and their trainees, physician assistants, and nursing staff.

Download or read book Lymph Node Cytopathology written by Stefan E. Pambuccian and published by Springer Science & Business Media. This book was released on 2010-10-17 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume in the Essentials in Cytopathology book series will focus on the cytopathology of lymph nodes. It will address the topic of fine needle aspiration of lymph nodes and fulfill the need for an easy-to-use and authoritative synopsis of lymph node cytopathology. The book with adopt an algorithmic diagnostic approach, starting from the cytomorphologic pattern of the lymph node aspirate. The focus will be on the appropriate and effective use of ancillary studies (immunohistochemistry, flow cytometry, fluorescence in situ hybridization and molecular techniques) and integration of their results into the final diagnosis. The book will present the cytopathologic features and differential diagnoses for the major cytologic patterns in lymph node fine needle aspiration. The entities typically falling within each of these patterns will be discussed with illustration of the spectrum of cytologic features, differential diagnoses and pitfalls. The book will cover the full spectrum of benign and malignant primary conditions of the lymph nodes, with emphasis on common disorders. Discussion of metastatic conditions will be restricted to those that are relevant to the differential diagnosis of primary lymphoid disorders. This book is designed as an easy to use resource that fits into the lab coat pocket, ideal for portability and quick reference. It is heavily illustrated and contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities encountered in lymph node aspirates. The accompanying text follows an easy to use pattern-based outline. A useful resource for every pathologist, cytopathologist, fellow and trainee.

Download or read book The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology written by Andrew S. Field and published by Springer Nature. This book was released on 2020-02-22 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text describes a system of reporting breast fine needle aspiration biopsy that uses five clearly defined categories, each described by a specific term and each with a specific risk of malignancy. The five categories are insufficient/inadequate, benign, atypical, suspicious of malignancy and malignant. Each category has a risk of malignancy and is linked to management recommendations, which include several options because it is recognized that diagnostic infrastructure, such as the availability of core needle biopsy and ultrasound guidance, vary between developed and low and middle income countries. This text includes key diagnostic cytological criteria for each of the many lesions and tumors found in the breast. The cytopathology of specific lesions is illustrated with high quality photomicrographs with clear figure descriptions. Chapters also discuss current and potential future ancillary tests, liquid based cytology, nipple cytology and management. An additional chapter provides an overview of an approach to the diagnosis of direct smears of breast fine needle aspiration biopsies. The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology provides a clear logical approach to the diagnosis and categorization of breast lesions by FNAB cytology, and aims to facilitate communication with breast clinicians, further research into breast cytopathology and related molecular pathology, and improve patient care.

Download or read book Current Status of Diagnostic Cytology written by Peter Pfitzer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in science is often promoted by a new method. Diagnostic cytology, however, developed slowly over a whole century, mainly in differentiating malignant from benign cells from various tissues. The decisive step in this development was the intensive investigation of one local ization by Papanicolaou: The application of cytology for screening in the field of gynecologic oncology made it an acknowledged technique. Consequently, materials inves tigated before were tested again on a larger scale and new ones were included into the program. The possibility of a wide-range application of this diag nostic method, which carries a low risk for the patient and is low in cost, attracted the specialists of many fields. One of the problems which has resulted is the coordination of training and quality assurance for a large group of people from different fields and with different interests and whose experience in morphology varies. In this volume general problems of cytology are dis cussed, as is the question "who is a medical cytologist?" Education and training are the topics of the contributions by Coleman, Holzner, Jenny, Koss and Muller, cover ing the situation in the European Community, Germany, Austria, Switzerland, and the USA. A special contribu tion by Lange concerns the situation of cytotechnologists, paramedicals important for cytologic screening programs.