Download or read book What s Wrong With My Mouse written by Jacqueline N. Crawley and published by John Wiley & Sons. This book was released on 2007-03-23 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Jacqueline N. Crawley, author of the First and Second Editions of What’s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice,continues to field calls and e-mails from molecular geneticists who ask: how do I run behavioral assays to find out what’s wrong with my mouse? Turn to What’s Wrong with My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the Second Edition up to date with the latest science. In addition, the Second Edition includes two new chapters: "Neurodevelopment and Neurodegeneration" discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis. "Putting It All Together" recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions. The final chapter, "The Next Generation," examines new and emerging technologies. Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor websites, and an extensive list of references, make this book a valuable and practical resource for students and researchers.
Download or read book Handbook of Contemporary Learning Theories written by Robert R. Mowrer and published by Psychology Press. This book was released on 2000-10-01 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mowrer and Klein have long been making contributions to the field of contemporary learning theories. Their first two-volume set included chapters authored by many of the leading researchers in the field of animal learning and focused primarily on Pavlovian theory and instrumental conditioning. These impartial texts were an important addition to the field and remain widely cited. Over the last decade research on the nature of the learning process has evolved considerably. The research in this new volume represents the cutting-edge contributions of first rate authors and co-authors. These 14 chapters deal with the theoretical perspectives concerning the nature of the learning process, as well as the innovative research that supports these positions. This text is bound to be invaluable to both students and faculty of psychology and related disciplines, as well as to outside scholars. Key features include: * an introductory chapter describing general theories of learning and the causes of the shift to more specific, contemporary theories; * five chapters detailing the research and theories of the nature of Pavlovian Conditioning; * four chapters dealing with the current thinking and research on the nature of instrumental operant conditioning; * three chapters describing the link between learning and physiology; and * a concluding chapter detailing the application of learning theory to abnormal psychology.
Download or read book Life s rewards written by Richard J. Beninger and published by Oxford University Press. This book was released on 2018-07-18 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its discovery in the 1960s, a vast and wide-ranging body of research has accumulated about the dopaminergic system. Life's Rewards: Linking Dopamine, Incentive Learning, Schizophrenia, and the Mind offers a broad synthesis of our current understanding of this chemical, addressing, amongst others, its intricate relationship with learning and memory, psychopathology, social co-operation, and drug abuse. Aimed at students and researchers in neuroscience and psychology, Life's Rewards: Linking Dopamine, Incentive Learning, Schizophrenia, and the Mind is essential reading for anyone interested in the relationship between dopamine and reward-related incentive learning.
Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
Download or read book Guide to Research Techniques in Neuroscience written by Matt Carter and published by Academic Press. This book was released on 2022-03-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step
Download or read book Herbal Supplements and the Brain written by S.J. Enna and published by FT Press. This book was released on 2012-05-07 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, many manufacturers of plant-based "neuroceuticals" claim their products can offer powerful benefits in brain function. However, the US government does not require these manufacturers to demonstrate their products’ effectiveness, leaving it difficult for consumers and health professionals to make decisions about the benefits and risks. In Herbal Supplements and the Brain: Understanding their Health Benefits and Hazards, two leading researchers provide this crucial information in clear language any intelligent reader can understand and use. They begin by introducing the fundamental principles of pharmacology, explaining how drugs and natural products can affect the body’s organs and organ systems. Using examples, they show how to determine whether an ingested substance can enter the bloodstream and reach its target at a concentration sufficient to have an effect. They also explain how natural products may influence blood levels of other substances, and discuss whether such interactions may diminish the effectiveness of prescription medications or alter normal body chemistry. Throughout, the authors emphasize factors relating especially to neuroceuticals and the brain. Individual chapters are devoted to nutritional supplements which promise to enhance memory, relieve pain, safely promote sleep, and aid in the treatment of depression or anxiety. Specifically, readers will find research-based coverage of Ginkgo biloba; St. John’s Wort; Valerian; Lemon Balm; Kava; Lavender; Kudzu, Daffodil, Passion Flower, and Camellia Tea and other caffeinated beverages.
Download or read book Anxious written by Joseph LeDoux and published by Penguin. This book was released on 2016-08-23 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: “A rigorous, in-depth guide to the history, philosophy, and scientific exploration of this widespread emotional state . . . [LeDoux] offers a magisterial review of the role of mind and brain in the generation of unconscious defense responses and consciously expressed anxiety. . . . [His] charming personal asides give an impression of having a conversation with a world expert.” —Nature A comprehensive and accessible exploration of anxiety, from a leading neuroscientist and the author of Synaptic Self Collectively, anxiety disorders are our most prevalent psychiatric problem, affecting about forty million adults in the United States. In Anxious, Joseph LeDoux, whose NYU lab has been at the forefront of research efforts to understand and treat fear and anxiety, explains the range of these disorders, their origins, and discoveries that can restore sufferers to normalcy. LeDoux’s groundbreaking premise is that we’ve been thinking about fear and anxiety in the wrong way. These are not innate states waiting to be unleashed from the brain, but experiences that we assemble cognitively. Treatment of these problems must address both their conscious manifestations and underlying non-conscious processes. While knowledge about how the brain works will help us discover new drugs, LeDoux argues that the greatest breakthroughs may come from using brain research to help reshape psychotherapy. A major work on one of our most pressing mental health issues, Anxious explains the science behind fear and anxiety disorders. Praise for Anxious: “[Anxious] helps to explain and prevent the kinds of debilitating anxieties all of us face in this increasingly stressful world.” —Daniel J. Levitin, author of The Organized Mind and This Is Your Brain on Music “A careful tour through the current neuroscience of fear and anxiety . . . [Anxious] will reward the informed reader.” —The Wall Street Journal “An extraordinarily ambitious, provocative, challenging, and important book. Drawing on the latest research in neuroscience (including work in his own laboratory), LeDoux provides explanations of the origins, nature, and impact of fear and anxiety disorders.” —Psychology Today
Download or read book Advanced Imaging Methods in Neuroscience written by João O. Malva and published by Frontiers Media SA. This book was released on 2022-01-11 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Head First written by David Tomen and published by Balboa Press. This book was released on 2022-11-25 with total page 849 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the author of NootropicsExpert.com and his YouTube channel, David Tomen offers a revolutionary reference and repair manual for your brain. Through studying the clinical research and experimenting with dozens of natural nootropic supplements, the author has successfully restored his own health. And now shares with you an all-natural method to take control of your own cognitive health. In Head First, 2nd Edition you’ll get: • Detailed reviews of 102 of the most popular natural nootropic supplements used today; supported by hundreds and hundreds of peer-reviewed clinical studies from leading research institutions and universities from around the world • Learn which supplements to buy and which to avoid • Get clear and easy to understand instructions on how to use each supplement including dosage recommendations (often different than what’s on the bottle) • Stay safe from possible side effects; avoid drug interactions • Know how each supplement works in your brain and why; neuroscience that anyone can understand and apply • A chapter on how your brain works and why these natural supplements work • 2 chapters on recommended nootropic stacks (supplement combinations) for treating; anxiety, ADHD, depression, anxiety, learning & memory, mental fatigue, OCD, PTSD, and more • Discover what functional and mainstream medicine has missed if you are dealing with memory problems, impaired thinking, mental fatigue, anxiety, or depression and how to deal with your issues naturally! Fans of David’s work and contribution to the neurohacking community are also encouraging their doctors and psychiatrists to make Head First, 2nd Editon part of their reference library. When you take care of your “Head First”, everything else naturally falls into place. You’re full potential is within reach at last. Today is the day to go “Head First”! And get your happy back. For the last decade, author and world-traveler David Tomen has worked to deal with Adult ADD. And the brain fog, mental fatigue and memory loss that comes with hypothyroidism. Through studying the clinical data and experimenting with dozens of natural nootropic supplements, the author has successfully restored his own health. With cognition, memory and mood better than before. Through his writing and videos, the author is now empowering people around the world to take control of their own cognitive health. Fans of David’s work and contribution to the neurohacking community are also encouraging their doctors and psychiatrists to make Head First part of their library. When you take care of your Head First, everything else falls into place. You’re full potential is within reach at last. Today is the day to go Head First!
Download or read book Modern Techniques in Neuroscience Research written by Uwe Windhorst and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1336 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the techniques used in modern neuroscience research with the emphasis on showing how different techniques can optimally be combined in the study of problems that arise at some levels of nervous system organization. This is essentially a working tool for the scientist in the laboratory and clinic, providing detailed step-by-step protocols with tips and recommendations. Most chapters and protocols are organized such that they can be used independently, while cross-references between the chapters, a glossary, a list of suppliers and appendices provide further help.
Download or read book Current Serials Received written by British Library. Document Supply Centre and published by . This book was released on 2007 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Optogenetics written by Arash Kianianmomeni and published by . This book was released on 2016 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Energy Rising written by Julia DiGangi and published by Harvard Business Press. This book was released on 2023-09-26 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Your success in life—at work and at home—rises when you harness the energy that powers your brain. A neuropsychologist explains how. Your drive to create change, catalyze impact, and build relationships all come from neuroelectrical energy—real, electrical impulses—firing in your brain. Who you are as a person depends on how you work with this energy. When this energy rises within you, you feel empowered and dynamic. But when this energy falls, you feel down, stressed, and defeated. You may feel as if you don't control your emotional energy, that it's an inevitable consequence of the world around you and the forces bearing down on you. But that's not the case. To reach your full potential, you can learn to recognize and harness the energy in your brain. Leading neuropsychologist Julia DiGangi will teach you how through eight "codes." Some of the codes will surprise you. All will fortify you. You will learn why these codes work and how to apply them to your own challenges through exercises and reflections. When you start viewing your life less about the activities you do and more about the natural energies within and around you, your power to live and lead with impact grows exponentially. Energy Rising offers you a provocative and neuroscientifically accurate path to greater emotional power, influence, and connection, both at work and at home. DiGangi's lab and clinical work have been conducted at Harvard, Columbia, Georgetown University, the University of Chicago, DePaul, and the University of Illinois Chicago. Her fMRI and EEG research has helped business leaders, parents, couples, educators, and military leaders. Her work, rooted in resilience after extreme stress, will show you how to effectively deal with struggles you currently face. She tells the stories of business leaders, parents, couples—and even combat veterans and trauma survivors—who used the eight codes to rise. Get ready to feel your energy rising.
Download or read book Essentials of Cognitive Neuroscience written by Bradley R. Postle and published by John Wiley & Sons. This book was released on 2015-01-08 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Cognitive Neuroscience guides undergraduate and early-stage graduate students with no previous neuroscientific background through the fundamental principles and themes in a concise, organized, and engaging manner. Provides students with the foundation to understand primary literature, recognize current controversies in the field, and engage in discussions on cognitive neuroscience and its future Introduces important experimental methods and techniques integrated throughout the text Assists student comprehension through four-color images and thorough pedagogical resources throughout the text Accompanied by a robust website with multiple choice questions, experiment vidoes, fMRI data, web links and video narratives from a global group of leading scientists for students. For Instructors there are sample syllabi and exam questions
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1992 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book Cyclin Dependent Kinase 5 Cdk5 written by Nancy Y. Ip and published by Springer Science & Business Media. This book was released on 2009-02-28 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cyclin Dependent Kinase 5 provides a comprehensive and up-to-date collection of reviews on the discovery, signaling mechanisms and functions of Cdk5, as well as the potential implication of Cdk5 in the treatment of neurodegenerative diseases. Since the identification of this unique member of the Cdk family, Cdk5 has emerged as one of the most important signal transduction mediators in the development, maintenance and fine-tuning of neuronal functions and networking. Further studies have revealed that Cdk5 is also associated with the regulation of neuronal survival during both developmental stages and in neurodegenerative diseases. These observations indicate that precise control of Cdk5 is essential for the regulation of neuronal survival. The pivotal role Cdk5 appears to play in both the regulation of neuronal survival and synaptic functions thus raises the interesting possibility that Cdk5 inhibitors may serve as therapeutic treatment for a number of neurodegenerative diseases.
Download or read book Encyclopedia of Movement Disorders written by and published by Academic Press. This book was released on 2010-02-26 with total page 1633 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Movement Disorders is a comprehensive reference work on movement disorders, encompassing a wide variety of topics in neurology, neurosurgery, psychiatry and pharmacology. This compilation will feature more than 300 focused entries, including sections on different disease states, pathophysiology, epidemiology, genetics, clinical presentation, diagnostic tools, as well as discussions on relevant basic science topics. This Encyclopedia is an essential addition to any collection, written to be accessible for both the clinical and non-clinical reader. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in the laboratory to the clinical features, pathophysiology and treatment of movement disorders. The Encyclopedia targets a broad readership, ranging from students to general physicians, basic scientists and Movement Disorder specialists. Published both in print and via Elsevier’s online platform of Science Direct, this Encyclopedia will have the enhanced option of integrating traditional print with online multimedia. Connects experimental findings made in the laboratory to the clinical features, pathophysiology, and treatment of movement disorders Encompasses a wide variety of topics in neurology neurosurgery, psychiatry, and pharmacology Written for a broad readership ranging from students to general physicians, basic scientists, and movement disorder specialists
