Download or read book Visual Psychophysics written by Zhong-Lin Lu and published by MIT Press. This book was released on 2013-10-11 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive treatment of the skills and techniques needed for visual psychophysics, from basic tools to sophisticated data analysis. Vision is one of the most active areas in biomedical research, and visual psychophysical techniques are a foundational methodology for this research enterprise. Visual psychophysics, which studies the relationship between the physical world and human behavior, is a classical field of study that has widespread applications in modern vision science. Bridging the gap between theory and practice, this textbook provides a comprehensive treatment of visual psychophysics, teaching not only basic techniques but also sophisticated data analysis methodologies and theoretical approaches. It begins with practical information about setting up a vision lab and goes on to discuss the creation, manipulation, and display of visual images; timing and integration of displays with measurements of brain activities and other relevant techniques; experimental designs; estimation of behavioral functions; and examples of psychophysics in applied and clinical settings. The book's treatment of experimental designs presents the most commonly used psychophysical paradigms, theory-driven psychophysical experiments, and the analysis of these procedures in a signal-detection theory framework. The book discusses the theoretical underpinnings of data analysis and scientific interpretation, presenting data analysis techniques that include model fitting, model comparison, and a general framework for optimized adaptive testing methods. It includes many sample programs in Matlab with functions from Psychtoolbox, a free toolbox for real-time experimental control. Once students and researchers have mastered the material in this book, they will have the skills to apply visual psychophysics to cutting-edge vision science.

Download or read book Agricultural Research Program written by U.S. Atomic Energy Commission. Oak Ridge Operations Office and published by . This book was released on 1964 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Agriculture Rural Development Food and Drug Administration and Related Agencies Appropriations for 2013 written by United States. Congress. House. Committee on Appropriations. Subcommittee on Agriculture, Rural Development, Food and Drug Administration, and Related Agencies and published by . This book was released on 2012 with total page 980 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Program Evaluation written by John M Owen and published by SAGE. This book was released on 2012-07-18 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a straightforward, practical introduction to evaluation for beginners and practitioners. It shows how to identify appropriate forms and approaches, using an original framework. The authors examine the role of evaluation in program development, and offer techniques for involving stakeholders in the planning process and for disseminating the evaluation findings. They use references to recent research and international examples.

Download or read book Early Diagnosis and Intervention in Predementia Alzheimer s Disease An Issue of Medical Clinics written by Jose L. Molinuevo and published by Elsevier Health Sciences. This book was released on 2013-05-28 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Medical Clinics covers the important advances surrounding the early intervention of Alzheimer's Disease. Guest edited by world-renowned experts from around the world, the topics covered will include evaluation of new diagnostic criteria, CSF biomarkers, diagnostic imaging, neurocognitive approaches, breaking clinical trials and more.

Download or read book Sample Preparation in LC MS Bioanalysis written by Wenkui Li and published by John Wiley & Sons. This book was released on 2019-02-25 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revised and Expanded Handbook Provides Comprehensive Introduction and Complete Instruction for Sample Preparation in Vital Category of Bioanalysis Following in the footsteps of the previously published Handbook of LC-MS Bioanalysis, this book is a thorough and timely guide to all important sample preparation techniques used for quantitative Liquid Chromatography–Mass Spectrometry (LC-MS) bioanalysis of small and large molecules. LC-MS bioanalysis is a key element of pharmaceutical research and development, post-approval therapeutic drug monitoring, and many other studies used in human healthcare. While advances are continually being made in key aspects of LC-MS bioanalysis such as sensitivity and throughput, the value of research/study mentioned above is still heavily dependent on the availability of high-quality data, for which sample preparation plays the critical role. Thus, this text provides researchers in industry, academia, and regulatory agencies with detailed sample preparation techniques and step-by-step protocols on proper extraction of various analyte(s) of interest from biological samples for LC-MS quantification, in accordance with current health authority regulations and industry best practices. The three sections of the book with a total of 26 chapters cover topics that include: Current basic sample preparation techniques (e.g., protein precipitation, liquid-liquid extraction, solid-phase extraction, salting-out assisted liquid-liquid extraction, ultracentrifugation and ultrafiltration, microsampling, sample extraction via electromembranes) Sample preparation techniques for uncommon biological matrices (e.g., tissues, hair, skin, nails, bones, mononuclear cells, cerebrospinal fluid, aqueous humor) Crucial aspects of LC-MS bioanalytical method development (e.g., pre-analytical considerations, derivation strategies, stability, non-specific binding) in addition to sample preparation techniques for challenging molecules (e.g., lipids, peptides, proteins, oligonucleotides, antibody-drug conjugates) Sample Preparation in LC-MS Bioanalysis will prove a practical and highly valuable addition to the reference shelves of scientists and related professionals in a variety of fields, including pharmaceutical and biomedical research, mass spectrometry, and analytical chemistry, as well as practitioners in clinical pharmacology, toxicology, and therapeutic drug monitoring.

Download or read book Critical Success Factors CSF s for 3P s Public Private Partnership Infra Structure Projects in Developing Countries written by Engr. Muhammad Akbar and published by Lulu.com. This book was released on 2018-12-25 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book enables government and international/local private sector construction companies to better understand the impact and significance of various important potential risk factors associated with Public, Private, Partnership constructional projects in Pakistan. At the same time, it also highlights the preferences of public and private sectors in the handling of these risk factors. The research work also helps concerned government departments and institutions for better future risk planning/management on P3 constructional projects and adjusting their strategies accordingly to attract maximum foreign investors in the country to achieve better value for money for the public.

Download or read book Describing Learning written by Australian Council for Educational Research and published by . This book was released on 1997 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major changes in the emphases of education programs in Australian schools have occurred since 1986. The states and territories collaborated to define the general content for a national curriculum in eight 'key learning areas'. At the same time, they developed a common framework for describing what students have learned in relation to that curriculum. This report presents a comprehensive picture of the key people, decisions, events, problems and successes as the states and territories embarked on making the new 'outcomes- based' approach a reality for teachers and students. The book contains: a detailed chapter from each state and territory education system; results from a 1996 national survey of principals and teachers; commentary and insights collected from teachers during school visits; and, evidence and examples of 'best practice' implementation strategies.

Download or read book Cerebrospinal Fluid in Neurologic Disorders written by and published by Elsevier. This book was released on 2017-11-17 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebrospinal Fluid in Neurologic Disorders, Volume 146 provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker. The second part addresses the main purpose of the volume, describing CSF from a research perspective in context with the most important diagnostic entities in neurology. The book's authors provide insight into the current understanding of CSF changes in these various conditions and what it tells us about the nature of neurological diseases. Furthermore, methodological aspects are discussed, as are shortcomings that need to be addressed. Finally, the book provides an outlook for potential directions that can be explored to improve the various aspects of CSF research with the ultimate goal of being incorporated in clinical practice. - Provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker - Addresses relevant research in context with the most important diagnostic entities in neurology - Edited by leading authors in CSF research from around the globe, presenting the broadest, most expert coverage available

Download or read book Laboratory Guide to the Methods in Biochemical Genetics written by Nenad Blau and published by Springer Science & Business Media. This book was released on 2008-05-31 with total page 860 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual deals specifically with laboratory approaches to diagnosing inborn errors of metabolism. The key feature is that each chapter is sufficiently detailed so that any individual can adopt the described method into their own respective laboratory.

Download or read book Annual Report of Intramural Research Program Activities written by National Institute on Alcohol Abuse and Alcoholism (U.S.). Intramural Research Program and published by . This book was released on with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Targeted Biomarker Quantitation by LC MS written by Naidong Weng and published by John Wiley & Sons. This book was released on 2017-07-31 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to offer a blueprint for overcoming the challenges to successfully quantifying biomarkers in living organisms The demand among scientists and clinicians for targeted quantitation experiments has experienced explosive growth in recent years. While there are a few books dedicated to bioanalysis and biomarkers in general, until now there were none devoted exclusively to addressing critical issues surrounding this area of intense research. Target Biomarker Quantitation by LC-MS provides a detailed blueprint for quantifying biomarkers in biological systems. It uses numerous real-world cases to exemplify key concepts, all of which were carefully selected and presented so as to allow the concepts they embody to be easily expanded to future applications, including new biomarker development. Target Biomarker Quantitation by LC-MS primarily focuses on the assay establishment for biomarker quantitation—a critical issue rarely treated in depth. It offers comprehensive coverage of three core areas of biomarker assay establishment: the relationship between the measured biomarkers and their intended usage; contemporary regulatory requirements for biomarker assays (a thorough understanding of which is essential to producing a successful and defendable submission); and the technical challenges of analyzing biomarkers produced inside a living organism or cell. Covers the theory of and applications for state-of-the-art mass spectrometry and chromatography and their applications in biomarker analysis Features real-life examples illustrating the challenges involved in target biomarker quantitation and the innovative approaches which have been used to overcome those challenges Addresses potential obstacles to obtain effective biomarker level and data interpretation, such as specificity establishment and sample collection Outlines a tiered approach and fit-for-purpose assay protocol for target biomarker quantitation Highlights the current state of the biomarker regulatory environment and protocol standards Target Biomarker Quantitation by LC-MS is a valuable resource for bioanalytical scientists, drug metabolism and pharmacokinetics scientists, clinical scientists, analytical chemists, and others for whom biomarker quantitation is an important tool of the trade. It also functions as an excellent text for graduate courses in pharmaceutical, biochemistry and chemistry.

Download or read book Project Health Assessment written by Paul S. Royer, PMP and published by CRC Press. This book was released on 2014-10-24 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Project managers, sponsors, team members, and involved stakeholders know when things aren’t going well. A frequent first indication is a missing or errant process. Project Health Assessment presents an innovative approach for assessing project processes through a set of ten critical success factors based on PMI’s PMBOK® Guide knowledge areas. The findings from such assessments can help project managers reduce project risk, improve stakeholder satisfaction, and increase the likelihood of project success, as demonstrated by 30+ assessments done over 15 years of putting this approach into practice. Project Health Assessment breaks down each PMBOK® Guide knowledge area into its process steps, inputs, and outputs and then creates critical success factor questions that evaluate its effectiveness and potential risk. These questions can be used by project managers to establish sufficient project processes or by external entities to evaluate a project and assess its overall risk The book illustrates critical success factor points through numerous case studies, including a step-by-step example of how to conduct a project health assessment from engagement acquisition through startup, initial assessment, and periodic follow-up assessments. The book provides several downloadable document, spreadsheet, and scheduling templates that practitioners can customize and use in their projects. Using these tools, you can avoid or minimize the cost of failed projects to your organization.

Download or read book Advances in Clinical Chemistry written by and published by Academic Press. This book was released on 2014-05-20 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 65 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of Clinical Chemistry and is the benchmark for novel analytical approaches in the clinical laboratory. Expertise of international contributors Latest cutting-edge technologies Comprehensive in scope

Download or read book Application of Next Generation Sequencing NGS and CRISPR Cas Systems in The Diagnosis of Infectious Diseases written by Yanfei Chen and published by Frontiers Media SA. This book was released on 2023-03-03 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1970 with total page 1060 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Diagnosis of Dementia and Cognitive Impairment written by Andrew J. Larner and published by MDPI. This book was released on 2019-12-10 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this special issue of Diagnostics, expert contributors have produced up-to-date research studies and reviews on various topics related to the diagnosis of dementia and cognitive impairment. The methods of the assessments discussed extend from simple neurological signs, which may be elicited in the clinical encounter, through cognitive screening instruments, to sophisticated analyses of neuroimaging and cerebrospinal fluid biomarkers of disease. It is hoped that these various methods may facilitate earlier diagnosis of dementia and its subtypes, and provide differential diagnosis of depression and functional cognitive disorders, as a prelude to meaningful interventions.