Download or read book Drug Discovery and Evaluation Methods in Clinical Pharmacology written by H.Gerhard Vogel and published by Springer Science & Business Media. This book was released on 2010-12-15 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Download or read book Network Pharmacology written by Shao Li and published by Springer Nature. This book was released on 2021-09-29 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
Download or read book Pharmacology and Applications of Chinese Materia Medica written by Hson-Mou Chang and published by World Scientific. This book was released on 1986 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first volume of a comprehensive 2-volume book covering modern pharmacological and clinical studies of the most commonly used Chinese herbal drugs. It contains monographs of 250 kinds of the most commonly used Chinese Materia Medica. The information on each herb was compiled by a research specialist active in the scientific investigation of that particular type of herb. The description on each drug includes an introduction (source, character and taste, actions and indications according to traditional Chinese medicine etc.), chemical composition, pharmacology, clinical studies, adverse effects and references. The translation of the book into English was done by qualified professionals in the field and the terms used are consistent with those used in Index Medicus, Chemical Abstracts and Botanical journals.
Download or read book Chinese Medical Herbology and Pharmacology written by John K. Chen and published by AOM Press. This book was released on 2004 with total page 1267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chinese Medical Herbology and Pharmacology integrates contemporary understanding of the ancient practice of Chinese herbal medicine with essential safety information for a context in which use of pharmaceutical and traditional medicines is increasingly integrated in the treatment of illness. In 1,266 information-packed pages, this text offers healthcare practitioners, researchers, educators and students information for a lifetime of learning and practice: 670 in-depth herb monographs; 1150 photographs, classic line drawings, and chemical structure diagrams; far-reaching insights from academic, clinical, research and regulatory professionals; traditional uses and combinations, dosages, toxicology, cautions and contraindications; safety index, herb-drug interactions, clinical studies and research; and more.
Download or read book Chinese Drugs of Plant Origin written by Weici Tang and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 1005 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditional Chinese medicine has been used for thousands of years by a large population. It is currently still serving many of the health needs of the Chinese people; and still enjoying their confi dence it is practised in China in parallel with modern Western medical treatment. In addition to scientific organisations dedi cated to modern Western medicine, e. g. the Chinese Academy of Medical Sciences and various medical schools, a series of parallel institutions have been established in China to promote traditional Chinese medicine, such as the Academy of Traditional Chinese Medicine and training institutions. Almost all hospitals in China have a department of traditional medicine. Furthermore, a large number of scientific journals are dedicated to traditional Chinese medicine, covering both experimental and clinical investigations. Medicinal materials constitute a key topic in the treatment of disease according to traditional Chinese medicine. The Chinese Pharmacopoeia (1985 edition) is therefore divided into two sepa rate volumes, Volume I containing traditional Chinese medicinal materials and preparations and Volume II containing pharmaceu tics of Western medicine. The oldest Chinese review of medicinal materials, Shennong Bencao Jing (100-200 A. D. ), covered 365 herbal drugs. The clas sic compilation in this field, Bencao Gangmu (Compendium of Materia Medica), was published in 1578 by Li Shi-zhen and recorded as many as 1898 crude drugs of plant, animal and min eral origin.
Download or read book Dietary Chinese Herbs written by Yanze Liu and published by Springer Science & Business Media. This book was released on 2015-05-18 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents up-to-date information on chemical, pharmacological, clinical studies and historical uses of common dietary Chinese herbs. Authored by native experts in the field, the reader is introduced to each herb with a brief chronological review of Chinese literature on dietary herb uses, with chapters dedicated to each selected herb including color photos for each herb. In addition, Chinese characters as well as the Latin botanical name indices, and chemical structures for the known active compounds are also provided. The clear layout examines the health benefits that have been studied for centuries, including current clinical and toxicological data. A wide range of Traditional Chinese Medicine (TCM) herbs are investigated for their suitability into daily diets for maintaining general wellness or disease prevention. In the past decades, natural health products, dietary supplements, functional foods, or nutraceuticals have emerged in the West due to the increasing demand for non-pharmaceutical healthcare products. Traditional Chinese Medicine disease prevention and treatment incorporates the use of foods, and herbal medicine in an integrated manner, and thus the dietary Chinese herbs in used in TCM for thousands of years could be sources for developing new, effective, and safe ingredients to capture the rapidly expanding opportunity in the global market place.
Download or read book The Pharmacology of Chinese Herbs Second Edition written by Kee C. Huang and published by CRC Press. This book was released on 1998-07-27 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Records cataloging the healing powers of natural substances - plants, minerals, and animal byproducts - date back more than 4,000 years. There is no denying the effectiveness of traditional Chinese medicine, yet - until recently - the roots of this knowledge were largely lost in superstition and folklore. However, the use of herbs as an alternative medical treatment for many illnesses has increased steadily over the last decade, particularly since such herbs are categorized as "Natural Food Products" and are not yet subject to strict control by the FDA. Reports published in 1996 indicate that more than 10% of the US population has used herbal remedies. This book does not debate the value of Eastern or Western medicine but brings together Chinese herbal lore and Western scientific methods in a current, comprehensive treatise on the pharmacology of Chinese herbs. This second edition of The Pharmacology of Chinese Herbs presents the chemical composition, pharmacological action, toxicity, and therapeutic value of 473 herbs. The book: Classifies herbs according to their therapeutic value Informs how active ingredients in herbs may adversely interact with other herbs or drugs Evaluates which herbs have the potential for more investigation and possible use as drugs Describes the pharmacological action of each herb based on recent scientific study and describes each herb according to Chinese pharmacopoeia and folk medicine Provides a review of Chinese medical history Presents information on how to use modern chemical techniques for enhancing or modifying herbal ingredients into better agents with more strength and activity What's New in the Second Edition Discussions on: Herbs and their specific effects on the immune system Herbs and fertility/infertility Anti-cancer herbs Anti-HIV herbs Anti-malarial herbs Ginseng and ginsenosides Anti-Alzheimer herbs Herbs affecting the nervous system
Download or read book SARS written by and published by . This book was released on 2004-01-01 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: SARS is a newly identified human infection caused by a corona virus unlike any other known human or animal virus in its family. The analysis of epidemiological information obtained from the sites of the outbreaks of SARS is still underway but the overall case fatality ratio is known to approach 11% although the rate among the elderly is much higher. Currently the major challenges for the treatment of SARS are: the source of the SARS virus and mode of transmission are still not well understood; there are problems with diagnostic tools; there is no effective treatment; and there is no vaccine for SARS. The above-mentioned difficulties and challenges have motivated national authorities health workers and scientists to explore the potential of complementary treatment. The results of research on integrated treatment with TCM and Western medicine showed that it is safe and that it also has some potential clinical benefits. Therefore the experts suggested that records of such experience could serve as reference material for treatment of SARS in the future. This publication is intended to share experience in the complementary treatment of SARS patients; share the experience of clinical studies in the field of traditional medicine for treatment of SARS between the physicians and researchers; and to further encourage and promote the quality of research in the filed of traditional medicine.
Download or read book Classical Chinese Medicine written by Liu Lihong and published by The Chinese University of Hong Kong Press. This book was released on 2019-04-19 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: The English edition of Liu Lihong’s milestone work is a sublime beacon for the profession of Chinese medicine in the 21st century. Classical Chinese Medicine delivers a straightforward critique of the politically motivated “integration” of traditional Chinese wisdom with Western science during the last sixty years, and represents an ardent appeal for the recognition of Chinese medicine as a science in its own right. Professor Liu’s candid presentation has made this book a bestseller in China, treasured not only by medical students and doctors, but by vast numbers of non-professionals who long for a state of health and well-being that is founded in a deeper sense of cultural identity. Oriental medicine education has made great strides in the West since the 1970s, but clear guidelines regarding the “traditional” nature of Traditional Chinese Medicine (TCM) remain undefined. Classical Chinese Medicine not only delineates the educational and clinical problems faced by the profession in both East and West, but transmits concrete and inspiring guidance on how to effectively engage with ancient texts and designs in the postmodern age. Using the example of the Shanghanlun (Treatise on Cold Damage), one of the most important Chinese medicine classics, Liu Lihong develops a compelling roadmap for holistic medical thinking that links the human body to nature and the universe at large.
Download or read book A Materia Medica for Chinese Medicine E Book written by Carl-Herman Hempen and published by Elsevier Health Sciences. This book was released on 2009-04-28 with total page 1019 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytotherapy or herbal medicine is the most important therapy within Chinese medicine and is being used increasingly in the West. A Materia Medica for Chinese Medicine: plants, minerals and animal products describes 400 of the most important plants, minerals and animal substances used as treatments by Chinese medical practitioners. The items included have been selected according to their degree of clinical relevance. Each remedy is clearly described and illustrated on two facing pages, making this an easily accessible reference for both students and practitioners of Chinese herbal medicine. The clearly laid out text presents the following details for each herb or substance included: - a detailed description of the characteristic features - indictions for safe use - medicinal and toxic effects - possible combinations with other substances - full-colour illustrations, generally two for each substance, showing the detailed characterisitcs of the item described A Materia Medica for Chinese Medicine has been written by two medically trained doctors who have worked as TCM therapists specializing in the use of Chinese herbs for more than 30 years. Based on their many years of teaching and practice, the book has been carefully compiled and designed to provide a concise and accurate practice-based reference for both students and practitioners.
Download or read book Creating a New Chinese Medicine and Pharmacology written by David Falkayn and published by The Minerva Group, Inc.. This book was released on 2003-05 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: CONTENTS Creating a New Medicine and Pharmacology New Developments in Fracture Treatment Non-Surgical Cure of Acute Abdominal Diseases New Treatment of Cataract
Download or read book Chinese Herbal Formulas and Applications written by John K. Chen and published by AOM Press. This book was released on 2009-01-01 with total page 1622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Companion volume to Chinese Medical Herbology and Pharmacology. This book takes the next step in presenting not only the traditional usage of Chinese herbal formulas, but a combined perspective of the pharmacological effects of formulas themselves with clinically relevant research evidence. As competencies in multiple health care disciplines continue to be raised the need for integrative understandings rise with it. Chinese Herbal Formulas and Applications brings together Chinese Herbal Medicine and expands this with the pharmaceutical effects and clinical research findings to use herbal medicines exclusively or in combination with the allopathic medicine. Enhancing the understanding of herbs and herbal formulas from multiple perspectives, Chinese Herbal Formulas and Applications is a resource for improved patient care and therapeutic outcome. OUTSTANDING FEATURES: Comprehensive explanation of the pharmacology of herbal medicinal formulas, and concurrent uses of herbal formulas and pharmaceuticals Documentation from clinical studies and published research Profiles of the doctors without whom there would be no Chinese medicine: insights into the historical context and backgrounds of those famous individuals who shaped our understanding of disease patterns, treatment strategies and herbal formulas. Contributions from over 100 academic, clinical, research and regulatory professionals who reviewed the text before publication, to complement the work of the authors. PLUS Detailed traditional and modern uses, preparation, administration, dosages, combinations, cautions, contraindications and toxicology. Authors comments are drawn from clinical experience. Appendices on herbal medicine for pregnancy and postpartum care and much more.
Download or read book Essentials of Chinese Materia Medica and Medical Formulas written by Shengyan Xi and published by Academic Press. This book was released on 2017-05-01 with total page 1018 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Chinese Materia Medica and Medical Formulas: New Century Traditional Chinese Medicine presents specific knowledge about the source, medicinal nature, action and application of more than 800 commonly-used Chinese materia medica, as well as the efficacy and application of more than 740 kinds of commonly-used Chinese medical formulas. Notably, all of the content is presented in table form, making the information easier to access, understand and apply. Each primary herbal medicine is introduced with color pictures, and each primary formula is presented with efficacy analysis pictures. The book provides readers with essential information on Chinese materia medica and formulas and how to use them accurately, including the most common Chinese materia medica used in clinics and in commonly used clinical formulas. This is an essential reference for traditional medical professionals and those interested in traditional Chinese medicine, including advanced undergraduate and postgraduate students. - Includes over 800 Chinese materia medica and 740 medical formulas with their essential information - Combines 514 color pictures of medicine material crude slices and 255 formulary efficacy analysis pictures - Organized with concise forms, facilitating understanding and memorization
Download or read book Herbal Medicine written by Iris F. F. Benzie and published by CRC Press. This book was released on 2011-03-28 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef
Download or read book Chinese Herbal Medicine written by Chongyun Liu and published by CRC Press. This book was released on 2004-07-28 with total page 1760 pages. Available in PDF, EPUB and Kindle. Book excerpt: A roadmap for easily navigating through the complexities of Chinese herbal medicine, Chinese Herbal Medicine: Modern Applications of Traditional Formulas presents information about herbal formulas in a practical and easy-to-access format. Bridging the gap between classroom study and the clinical setting, the book supplies information on disease sym
Download or read book Chinese Medicine in Early Communist China 1945 1963 written by Kim Taylor and published by Routledge. This book was released on 2004-08-02 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using original sources, this significant text looks at the transformation of Chinese medicine from a marginal, side-lined medical practice of the early twentieth century, to an essential and high-profile part of the national health-care system under the Chinese Communist Party. The political, economic and social motives which drove this promotion are analyzed and the extraordinary role that Chinese medicine was meant to play in Mao Zedong's revolution is fully explored for the first time, making a major contribution to the history of Chinese medicine.
Download or read book Chinese Medicine in Early Communist China 1945 63 written by Kim Taylor and published by Psychology Press. This book was released on 2005 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kim Taylor looks at the transformation of Chinese medicine from a marginal, sidelined medical practice of the early 20th century, to an essential and high profile part of the national health-care system under the Chinese Communist Party.
