Download or read book Craniofacial Structures in Connective Tissue Disorders written by Society of Craniofacial Genetics. Symposium and published by . This book was released on 1990 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Craniofacial Structures in Connective Tissue Disorders written by Society of Craniofacial Genetics. Symposium and published by . This book was released on 1990 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Craniofacial Structures in Connective Tissue Disorders written by Jaime L. Frias and published by John Wiley & Sons. This book was released on 1990-01 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers a detailed study of the developmental aspects of craniofacial dysmorphology, covering various clinical and basic aspects of the craniofacial structure in connective tissue disorders.
Download or read book Craniofacial Mesenchyme in Morphogenesis and Malformation written by Society of Craniofacial Genetics. Symposium and published by Alan R. Liss. This book was released on 1984 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cranial Facial Structures and Connective Tissue Disorders written by and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Craniofacial Development written by Peter Thorogood and published by . This book was released on 1988 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Craniofacial Morphology of Juvenile Mice with Osteogenesis Imperfecta written by Ashley T. Steele and published by . This book was released on 2020 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteogenesis Imperfecta (OI) is a heritable connective tissue disorder affecting the synthesis and structure of type I collagen (Col1) due to autosomal dominant mutations in proa1(I) or proa2(I) collagen genes (COL1A1 and COL1A2). Clinical manifestations of the severe OI type III include bone fragility, reduced physical stature, and midface hypoplasia resulting in a "triangle face" phenotype. Current treatment options have low-success rates and focus primarily on alleviating symptoms through surgical interventions and pharmacologic use of antiresorptive drugs. The homozygous OI murine (OIM-/-) mouse model has a nonlethal, recessively inherited mutation of the COL1A2 gene and exhibits adult cranial and post-cranial phenotypes similar to humans with severe OI type III; however, the juvenile phenotype is unknown. The goals of this study are: (1) to determine if significant differences in craniofacial skeletal shape and size are present at the age of weaning (21 days/4 weeks) in the OIM-/- mice compared to the wild type (WT) and (2) to determine if these differences are still significant when adjusted for the allometric effects of body size. OIM-/- and WT littermates were weaned at 21 days and scanned in-vivo with a Skyscan 1176 micro-CT system. Craniofacial geometric landmarks were collected using 3D Slicer software and were subsequently used to calculate interlandmark distances (ILDs) and centroid sizes. ILDs were scaled against skull/mandible centroid size to account for the effect of overall body size on shape analyses. Mann-Whitney U-tests were used to compare both absolute and relative (scaled) ILDs between the genotypes. Craniomandibular centroid sizes and absolute linear distances (skull, rostrum, palate, and mandible lengths) demonstrate that the OIM-/- mice are smaller overall than their WT littermates. When scaled to centroid size, juvenile OIM-/- mice have a decrease in nasal length, mandibular diastema length, and basicranium but an increase in cranial vaults, midface heights, and both maxillary and mandibular toothrow lengths compared to WT mice. For a given skull length, OIM-/- mice have shorter faces in both the anteroposterior and dorsoventral dimensions. The morphometric changes seen in the juvenile OIM-/- mice replicate the "triangle face" and relative macrocephaly that is commonly seen in human pediatric populations with OI. This suggests that this mouse model can potentially be used to investigate the structural changes underlying the human OI phenotype and for potential therapeutic interventions, such as biomechanical loading, myostatin knock-out, and pharmaceutical therapies. Additionally, the results of this study can be used to inform future investigations of Col1 in craniofacial development. Continuing to evaluate the etiology of this disorder can lead to better treatment options to improve the quality of life for patients with OI, especially pediatric patients.
Download or read book Mineralized Tissues in Oral and Craniofacial Science written by Laurie K. McCauley and published by John Wiley & Sons. This book was released on 2012-06-05 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mineralized Tissues in Oral and Craniofacial Science is a major comprehensive update on knowledge in the field of mineralized tissues in the oral and craniofacial region. Drs. McCauley and Somerman assembled an international team of researchers and clinicians, offering a global perspective on the current knowledge in this field. Basic and clinical correlates reinforce the significance of research to clinical diagnoses and therapies, written in a manner that lends easily to their use for case study teaching venues. Section 1 features the many aspects of bone in the craniofacial region, including embryology, cell biology, and stem cell biology. Section 2 focuses on teeth-tooth development, dentin, enamel, cementum, and tooth regeneration. Section 3 discusses the interaction between bones and teeth, including those associated with inflammatory processes, periodontal ligaments, biomechanics, and other impact factors-such as nutrition, metabolic bone diseases and therapeutic modalities. The novel approach of linking the basic principles of the cell and molecular biology of hard tissues to clinical correlates will appeal to readers at all levels of their research careers, both students and faculty; faculty interested in a comprehensive text for reference; and clinicians interested in the biologic aspects of bones and teeth.
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book Syndromes of the Head and Neck written by Robert J. Gorlin and published by McGraw-Hill Companies. This book was released on 1976 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Craniofacial Malformations written by Michel Stricker and published by . This book was released on 1990 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work covers craniofacial malformations and growth, and their treatment, surgery and classification. Written for practising plastic surgeons and maxillofacial surgeons, it should also be of interest to oral and ENT surgeons and orthodontists.
Download or read book Bones and Cartilage written by Brian K. Hall and published by Academic Press. This book was released on 2014-12-23 with total page 911 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1990 with total page 1128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Injectable Biomaterials written by Brent Vernon and published by Elsevier. This book was released on 2011-01-24 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel injectable materials for non-invasive surgical procedures are becoming increasingly popular. An advantage of these materials include easy deliverability into the body, however the suitability of their mechanical properties must also be carefully considered. Injectable biomaterials covers the materials, properties and biomedical applications of injectable materials, as well as novel developments in the technology.Part one focuses on materials and properties, with chapters covering the design of injectable biomaterials as well as their rheological properties and the mechanical properties of injectable polymers and composites. Part two covers the clinical applications of injectable biomaterials, including chapters on drug delivery, tissue engineering and orthopaedic applications as well as injectable materials for gene delivery systems. In part three, existing and developing technologies are discussed. Chapters in this part cover such topics as environmentally responsive biomaterials, injectable nanotechnology, injectable biodegradable materials and biocompatibility. There are also chapters focusing on troubleshooting and potential future applications of injectable biomaterials.With its distinguished editor and international team of contributors, Injectable biomaterials is a standard reference for materials scientists and researchers working in the biomaterials industry, as well as those with an academic interest in the subject. It will also be beneficial to clinicians. Comprehensively examines the materials, properties and biomedical applications of injectable materials, as well as novel developments in the technology Reviews the design of injectable biomaterials as well as their rheological properties and the mechanical properties of injectable polymers and composites Explores clinical applications of injectable biomaterials, including drug delivery, tissue engineering, orthopaedic applications and injectable materials for gene delivery systems
Download or read book The Neural Crest written by Nicole Le Douarin and published by Cambridge University Press. This book was released on 1999-11-28 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.
Download or read book Fundamentals of Craniofacial Malformations written by Ulrich Meyer and published by Springer Nature. This book was released on 2021-06-24 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first volume in an interdisciplinary three-book series covering the full range of biological, clinical, and surgical aspects in the evaluation, diagnosis, and treatment of patients with craniofacial malformations. This volume opens by considering general topics such as developmental biology and disease classification and then examines in depth the biological basis of the various malformations, including craniosynostoses, cleft-lip and palate with complex orofacial clefts, branchio-oculo-facial syndromes, rare syndromes, soft tissue malformations, and dysgnathia. Psychological aspects, including psychological evaluation methods and therapies and quality of life issues, are then addressed. Finally, all relevant clinical, radiological, and genetic investigations are described and important diagnostic issues are explored. Featuring numerous high-quality illustrations, the book will be of high value for all clinicians, researchers, and postgraduate students who deal with these malformations. The accompanying two volumes describe treatment principles and present in an atlas manner all relevant surgical techniques in detail. The content of this multivolume set, written by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this medical field.
Download or read book Annual Report written by National Institute of Dental Research (U.S.) and published by . This book was released on with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
