Download or read book COVID 19 s Consequences on the Cardiovascular System written by Fabian Sanchis-Gomar and published by Elsevier. This book was released on 2024-04-04 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: COVID-19 Consequences on Cardiovascular System: Immediate, Intermediate, and Long-Term Complications covers all the aspects related with the interplay between SARS-COV-2 infection and the cardiovascular system, from bench to bedside and from acute infection to long-term complications. Written by a team of experts, this book is a one-stop-shop reference for both healthcare professionals and researchers who require a comprehensive view into the deleterious effects of COVID-19 on the cardiovascular system, the relationship of cardiovascular risk factors with COVID-19 prognosis, and further insights on the biomarkers that currently make it possible to predict and monitor the evolution of the disease at the cardiovascular level. Scientific evidence demonstrates that while COVID-19 primarily affects the lungs, it also affects multiple organs, particularly the cardiovascular system, with its most common complications being arrhythmia, cardiac injury, fulminant myocarditis, heart failure and pulmonary embolism. Covers all the current scientific pieces of evidence about the effects of COVID-19 on the heart and cardiovascular system from both a basic and a clinical point of view. Discusses immediate, intermediate, and long-term complications of COVID-19 on the cardiovascular system. Includes studies conducted worldwide by well-known experts in related fields.

Download or read book COVID 19 s Consequences on the Cardiovascular System written by Fabian Sanchis-Gomar and published by Elsevier. This book was released on 2024-06 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific evidence demonstrates that while COVID-19 primarily affects the lungs, it also affects multiple organs, particularly the cardiovascular system; its most common complications are arrhythmia, cardiac injury, fulminant myocarditis, heart failure, and pulmonary embolism. COVID-19’s Consequences on the Cardiovascular System: Immediate, Intermediate, and Long-Term Complications covers all aspects related to the interplay between SARS-COV-2 infection and the cardiovascular system, from bench to bedside and from acute infection to long-term complications. Written by a team of experts, this book is a one-stop-shop reference for healthcare professionals and researchers who require a comprehensive view of the deleterious effects of COVID-19 on the cardiovascular system. It discusses the relationship of cardiovascular risk factors with COVID-19 prognosis. It offers further insights into the biomarkers that currently make it possible to predict and monitor the evolution of the disease at the cardiovascular level.

Download or read book Cardiovascular Complications of COVID 19 written by Maciej Banach and published by Springer Nature. This book was released on 2022-12-28 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first comprehensive approach on COVID-19 cardiac complications, both during the acute phase as well as in the long-COVID period. It provides an up-to-date and highly illustrated summary of the biology of SARS-CoV-2, the course of COVID-19, risk factors that worsen the disease in COVID-19 patients, clinical features of COVID-19 patients, COVID-19 cardiological complications, treatment, and prevention methods, and long-term cardiological aspects of COVID-19. Chapters provide the reader with a contemporary perspective on the emerging links between COVID-19 and cardiovascular disease. In addition, this volume discusses the clinical implications and therapeutic goals in patients with COVID-19 and cardiac complications, as well as possible therapeutic options. It also offers clear recommendations on how to manage (both non- and pharmacologically) to avoid the increased number of COVID-19 related deaths due to CVD and its risk factors. Cardiovascular Complications of COVID-19 will be the primary resource for physicians, residents, fellows, and nursed and medical students in the fields of cardiology and COVID-19/infectious diseases as well as healthcare providers that initiate preventive activities and dedicated programs.

Download or read book Cardiovascular Complications of COVID 19 written by Umair Mallick and published by Springer Nature. This book was released on 2022-02-10 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the evidence behind the relationship between COVID-19 and heart disease based on emerging state-of-the-art data. The rapid and unexpected global spread of the COVID-19 has revealed proportional levels of cardiovascular and metabolic complications. A myriad of pathogenetic mechanisms has come to the surface. There is still much research required to define whether cardiovascular disease causes COVID-19 complications or that cardiovascular disease appears as a result of the infection and which mechanisms are responsible. With cardiovascular and metabolic diseases already at pandemic levels and expected to increase further, this book provides readers with an urgent and thorough analysis of this association. Cardiovascular Complications of COVID-19: Risk, Pathogenesis and Outcomes provides answers to the increasing numbers of questions related to heart disease in COVID-19, highlighting the association between these pandemics and including risk factors, mechanisms and how these may impact diverse patients populations. It describes how COVID-19 impacts older patients and those with metabolic illnesses such as obesity and diabetes mellitus, while providing an overview of the observed gender dichotomy among patients. It therefore represents an essential resource not only for all cardiovascular physicians but also for any healthcare professionals managing patients with these diseases or those exploring COVID-19.

Download or read book COVID 19 and the Heart A Case Based Pocket Guide written by Muhammad Saad and published by McGraw Hill Professional. This book was released on 2021-10-07 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: From frontline experts on the topic—everything you need to know about COVID-19 and how it affects the heart COVID-19’s effect on the cardiovascular system continues to drive increases in morbidity and mortality. Building a solid understanding of the disease spectrum is critical for accurately diagnosing, treating, and managing patients with heart issues in the time of COVID. Written by a team of experts who worked on the frontlines in New York City throughout the worst of the pandemic, COVID-19 and the Heart: A Case-Based Pocket Guide is a one-of-a-kind resource for providing safe, effective care for COVID-19-related heart conditions. Designed for quick and easy learning and on-the-spot clinical decision making, this practical guide is organized into chapters based on genuine clinical cases and provides the best approach for each one. The authors highlight key points throughout the clinical content for easy review, and provide up-to-date information on clinical trials/vaccines, diagnostic and treatment algorithms, therapeutics, monitoring, and patient education. Ideal for healthcare workers actively engaged in the ongoing pandemic and students seeking to build their expertise, COVID-19 and the Heart is the go-to guide to making the right clinical judgments with respect to the cardiac manifestations of COVID-19. COVID-19 and the Heart starts with the physiology of COVID-related heart disease, and walks you through COVID’s effect on: ACS Valvular heart disease Arrythmia Pericardial disease Heart failure Shock Thromboembolism Hypertension

Download or read book COVID 19 and the Cardiovascular System written by Brian C. Case and published by Elsevier. This book was released on 2024-10-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management comprehensively covers COVID-19's impact on the cardiovascular system. Coverage includes the pathophysiology, clinical manifestations, diagnostic approach, treatment options, and clinical outcomes of patients presenting with COVID-19 with cardiac involvement. In a concise but comprehensive manner, the book's content reviews the epidemiology, risk factors, pathophysiology of COVID-19, cardiovascular clinical manifestations, non-invasive and invasive diagnostic evaluation, therapeutic options, outcomes data, role of the COVID-19 vaccine, and long-term outcomes/management.This is the perfect reference for basic and clinical researchers in cardiovascular medicine as well as practicing clinical cardiologists who are dealing with COVID-19 patients with cardiac involvement. - Explains the pathophysiology, clinical manifestations, diagnostic approach, treatment options, and clinical outcomes of patients presenting with COVID-19 and cardiac involvement - Elucidates new and emerging options to treat this disease process - Provides concise, well validated, published data available in one single resource

Download or read book Covid 19 and Its Impact on Cardiovascular Health written by Robin Davidson and published by States Academic Press. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronavirus disease (Covid-19) refers to an infectious disease caused by the SARS-CoV-2 virus. It spreads when an infected person exhales droplets and very small particles containing the virus. The signs and symptoms of Covid-19 might vary but commonly include headache, breathing difficulties, loss of taste, fever, loss of smell, coughing and exhaustion. The primary presenting symptom of Covid-19 has been reported to be heart palpitations in patients who do not have a cough or fever. The Covid-19 virus has been recently shown as a major risk factor for cardiovascular disorders including myocarditis, myocardial injury, coagulation abnormalities, pericarditis, cardiac arrest, arrhythmias and heart failure in patients.This book provides significant information to help develop a good understanding of Covid-19 and its impact on cardiovascular health. It aims to shed light on some of the unexplored aspects of this disease. A number of latest researches have been included to keep the readers up-to-date with the global concepts in this medical condition.

Download or read book Regulation of Coronary Blood Flow written by Michitoshi Inoue and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.

Download or read book Cardiac Care and COVID 19 Perspectives in Medical Practice written by Ozgur KARCIOGLU and published by Bentham Science Publishers. This book was released on 2021-08-24 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac Care and COVID-19: Perspectives in Medical Practice is an accessible reference on diagnoses and treatment modalities for cardiac diseases in general, and emergency cardiac conditions to be more specific, with respect to the current COVID-19 pandemic. Chapters in the book give updated descriptions of common problems in emergency medicine and cardiovascular disease. Each chapter is dedicated to a specific cardiovascular disease and explains management principles, diagnostic procedures and therapy. Examples of medical cases have also been used to highlight complex issues to give a concrete understanding of the cardiac care in COVID-19 patients to the medical practitioner, whether they are involved in critical care or in outpatient clinics. Key Features: - Clinical guidelines for critical care and cardiovascular management of COVID-19 patients - Topic-based information about cardiovascular diseases - Covers a range of cardiovascular problems including myocarditis, arrhythmias, chest pain, acute coronary syndrome - Information on pulmonary embolism and associated problems - Reader friendly presentation - Case-based examples for explaining concepts The range of topics combined with the simple presentation make this an essential reference for healthcare workers in emergency medicine, cardiology and nursing. General physicians interested in the cardiovascular impact of COVID-19 will also benefit from the information provided in the book.

Download or read book Inflammatory Cardiomyopathy DCMi Pathogenesis and Therapy written by Heinz-Peter Schultheiss and published by Springer Science & Business Media. This book was released on 2011-01-30 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiomyopathy is one of the most frequent causes of heart failure. It is often associated with inadequate heart pumping or other heart function abnormalities. There are many different causes of the disease, therefore many different kinds of cardiomyopathies exist. This volume, written by a leading expert, focuses on inflammatory CM, belonging to the Dilated Cardiomyopathies (DCMi). It covers epidemiology/prognosis, pathology, immunology, diagnosis and treatment strategies.

Download or read book Cardiovascular System and SARS CoV 2 written by Jucier Gon√ßalves J√∫nior and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: During SARS-CoV-1 and Middle East Respiratory Distress Syndrome (MERS) outbreaks it was observed a particularly elevated incidence of cardiovascular disease among patients. With COVID-19, this correlation becomes evident again. However, the cardiovascular impacts by COVID-19 pandemic are not yet well established although publications about its potential deleterious effects are constant. Thus, aimed to carry a systematic review of the literature with meta-analysis, the following question was used as a guide: what practical contributions does the scientific literature produced in the period of 2019-2020 has to offer about the impact of the COVID-19 on cardiovascular system? A systematic review of the literature using the Virtual Health Library (VHL) and PubMed with the following descriptors: #1 ,Äúcardiovascular disease,Äù [MeSH] AND #2 ,ÄúCOVID-19,Äù [keyword], as well as their equivalents in the Portuguese and Spanish language, during the period from December 2019 to March 2020 was performed. One hundred articles were found in Pubmed and twenty-seven were selected. In VHL there are 59 articles and four were selected totaling thirty-one papers. The findings were then divided into three subcategories: Etiology, Physiopathology and Risk factors of SARS-CoV-2 in Cardiovascular System; Clinical presentation, laboratory markers and imagenological aspects of SARS-CoV-2 in cardiovascular system; and Anti-Hypertensive Drugs, Cardiovascular System and SARS-CoV-2. When it comes to the cardiovascular system, these issues are aggravated and urge as a joint commitment from researchers, medical and governmental organizations to carry out more robust studies with bold methodologies aimed at mapping prognostic factors and assertive therapeutic approaches in the management of cardiovascular complications of COVID- 19.

Download or read book Myocardial Injury written by John J. Spitzer and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chapters of this book represent contributions by plenary lecturers and invited symposium speakers of the Fourth Annual Meet ing of the American Section of the International Society for Heart Research, held on May 26-29, 1982 in New Orleans, Louisiana. The aim of the Organizing Committee was to present an up-to-date picture of our knowledge of myocardial injury which would be equally useful to basic scientists and clinicians. The papers of this volume are divided into two groups: a) those dealing primarily with techniques to study myocardial injury, and b) those that discuss the different types of myocardial lnJury. The grouping of the papers within each of these headings roughly corresponds to the symposia presented at the meeting. I wish to acknowledge the financial support of the National Institutes of Health. Without grant HL 29149, the program could not have been financed. Contributions from the following companies were also gratefully received: Ayerst Laboratories, Ciba-Geigy, Merck Sharp and Dome, Pfizer Laboratories Division, A.H. Robbin Co., Smith-Kline Corporation, U.S.V. Pharmaceutical Co., and The Upjohn Co. My thanks are due to the members of The Organizing Committee (Drs. Gregory J. Bagby, Gerald S. Berenson, Alastair H. Burns, Harvey I. Miller, Robert Roskoski, Jr., and Judy A. Spitzer) for their help and support, and to the Secretary of the Meeting, Ms. L. Beatrice Abene for her excellent assistance. John J. Spitzer, M.D.

Download or read book Cardioimmunology Inflammation and Immunity in Cardiovascular Disease written by Mohamed Boutjdir and published by Frontiers Media SA. This book was released on 2020-01-30 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Post COVID 19 Conditions and the Cardiovascular System written by Iana Simova and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: One out of four patients affected by COVID-19 will experience persistent (>3-4¬†weeks) signs and symptoms (Post COVID-19 conditions or Post-Acute Sequelae of SARS-CoV-2 ,Äì PASC) and this fact will have a major significance for the healthcare and economic systems in the upcoming years. The cardiovascular system is one of the key targets for the Post COVID-19 syndrome, given the pathogenesis of the virus and prevalence of ACE-2 receptors. According to our initial personal experience via the¬†campaign ,ÄúLife after COVID,Äù of the Bulgarian Cardiac Institute, a substantial proportion of patients having suffered from COVID-19 develop long-term cardiovascular consequences. They could range from rhythm disorder and blood pressure variation, through impairment of myocardial mechanics and heart failure, and to acute vascular manifestations of Post COVID-19 conditions, such as acute coronary syndrome, acute pulmonary embolism, and acute limb ischemia. These cardiovascular complications require special and dedicated medical attention, and we could share our personal experience on the matter.

Download or read book Intrinsic Cardiac Effects of Severe Acute Respiratory Syndrome Coronavirus 2 in Coronavirus Disease 2019 written by Brittany Danielle Brumback and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac arrhythmias, particularly ventricular arrhythmias, can be life-threatening and caused by both congenital genetic mutations and acquired cardiac injury. My thesis work was originally focused on delineating the effects of genetic mutation-driven dysregulation of a protein called Hey2 in Brugada Syndrome, a complex disease characterized by a predisposition to dangerous arrhythmias originating in the right ventricular outflow tract. In response to the pandemic, my thesis work shifted toward understanding the mechanisms of cardiovascular injury in Coronavirus disease 2019 (COVID-19), which is associated with serious cardiovascular complications, including ventricular arrhythmias and sudden cardiac death as well as endothelial dysfunction and coagulopathies. While the main dissertation is focused on the COVID-19 work, the original Hey2 project is covered in a supplemental chapter. COVID-19 patients can present with serious and sometimes lethal cardiovascular manifestations of the disease. Patients with severe cases of COVID-19 often suffer ventricular arrhythmias and sudden cardiac death, leading to increased morbidity and mortality, especially for patients with predisposing cardiovascular diseases. There is also substantial clinical evidence of patients experiencing acute myocardial infarctions, which may be caused by either direct damage to the myocardium or from vascular dysfunction that leads to blood clots and ultimately occlusions. Currently, there is significant discussion in the field about whether this cardiac damage is being caused by direct viral infection of the heart or due to systemic inflammatory effects. Many groups have sought to determine whether it is likely that SARS-CoV-2 could directly infect the heart via the ACE2 receptor. SARS-CoV-2 utilizes the ACE2 receptor to bind to cellular membranes and enter susceptible cells. Many groups have performed single-cell RNA-sequencing studies have been performed on human hearts that indicate ACE2 RNA is expressed in multiple cell types in the heart, with pericytes having the highest expression. Pericytes are perivascular cells that are found in abundance in the microvasculature in all vascularized organs where they regulate numerous functions, including vessel growth, permeability, and contractility. Since pericytes play a critical role in supporting endothelial cells and maintaining vascular integrity, we and others hypothesized that pericytes may be a culprit for cardiovascular damage in COVID-19. In healthy vessels, intact endothelial junctions would prevent SARS-CoV-2 was reaching pericytes due to size exclusion. However, if vessels have compromised barriers due to diseases, such as diabetes, SARS-CoV-2 could cross the barrier and infect pericytes, which could then lead to endothelial cell activation and inflammation. This could in turn lead to the coagulopathies and infarcts that are being reported in COVID-19 patients. In my thesis work, I started by collaborating with Dr. Michael Diamond's lab to combine the expertise and resources necessary to study the intrinsic cardiac effects of SARS-CoV-2 in COVID-19. Together, we adapted the Rentschler lab's previously establish human organotypic cardiac slice culture methodology to evaluate cellular tropism of SARS-CoV-2 in explanted donor human hearts rejected from transplantation. We identified cardiac pericytes as a direct target of SARS-CoV-2 infection in organotypic cardiac slices and then collaborated with Dr. Kory Lavine's lab to further evaluate viral entry and downstream effects of infection in primary cardiac pericytes. We found that primary cardiac pericytes were productively infected by SARS-CoV-2; however, we determined that other types of primary human pericytes from other organs, including the brain and placenta, were not infected likely due to significantly lower expression of the main viral entry receptor, ACE2, compared to cardiac pericytes. Furthermore, we determined that viral entry into cardiac pericytes is mediated by endosomal proteases rather than transmembrane serine proteases as seen in the lung epithelium. We demonstrate that cardiac pericyte infection leads to upregulation of Type I interferon signaling, inflammatory markers, and mediators of vasoreactivity, along with NF-[kappa]B cell death, with viability being partially improved by cytokine inhibition. Interestingly, we demonstrate that endothelial cell exposure to infected pericytes and their supernatant can lead to upregulation of Type I interferon signaling and neutrophil and T-cell chemokines combined with dysregulation of thrombosis mediators, further linking infected cardiac pericytes with endothelial dysfunction. And finally, we present evidence of cardiac pericyte infection in COVID-19 myocarditis patients. Together, the results in my thesis work demonstrate that human cardiac pericytes are susceptible to SARS-CoV-2 infection and suggest a role of pericyte infection in COVID-19.

Download or read book Pediatric Cardiac Surgery written by Constantine Mavroudis and published by John Wiley & Sons. This book was released on 2013-02-04 with total page 978 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric cardiac surgery is a dynamic, fast-moving field. Busy practitioners, like you, need clear and comprehensive guidance you can rely on to ensure optimal patient care. For over 25 years Pediatric Cardiac Surgery has been the gold-standard reference for pediatric and adult congenital heart surgeons, pediatric and congenital cardiologists, intensivists, anesthesiologists, residents and nurses. Now, in this thoroughly revised fourth edition, you again get trusted, complete coverage of the field with timely new features and expert reviews of critical topics including heart transplantation, emerging modalities for diagnosing congenital heart and tracheal defects, the surgical technique of Fontan conversion with arrhythmia surgery, the medical challenges of managing adult CHD patients, and more. This new edition includes: Contributions from over 65 world-renowned experts More beautiful illustrations, by renowned medical illustrator Rachid Idriss, which have brought acclaim to previous editions Reviews of the embryology, physical findings, diagnostic criteria, and therapeutic choices for each disease entity and describes the latest in surgical techniques in each chapter All-new chapters that guide readers through new treatment options and other key developments since the publication of the third edition highlighting recent advances in congenital heart surgery. All-new new chapters that review advances in right ventricular to pulmonary artery conduits, arrhythmia surgery, double outlet ventricles, and adult congenital heart disease, among other key topics.

Download or read book Acute Heart Failure written by Alexandre Mebazaa and published by Springer Science & Business Media. This book was released on 2009-12-24 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first book to cover extensively the diagnosis and management of this complex condition. The book reflects the considerable amounts of new data reported and many new concepts which have been proposed in the last 3-4 years looking at the epidemiology, diagnostic and treatment of acute heart failure.