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Book Computer Aided Interval Change Analysis of Microcalcifications on Mammograms for Breast Cancer Detection

Download or read book Computer Aided Interval Change Analysis of Microcalcifications on Mammograms for Breast Cancer Detection written by and published by . This book was released on 2005 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this project is to develop a computer-aided diagnosis (CAD) system for automatic interval change analysis of microcalcification clusters on mammograms. Based on our regional registration method a local area on the prior that may contain the corresponding cluster is determined. A search program is used to detect cluster candidates within the local area. The cluster on the current image is then paired with the candidates to form true (TP-TP) or false (TP-FP) pairs. A correspondence classifier (CC) using automatically extracted features is designed to reduce the false pairs. A temporal classifier (TC) based on current and prior information is used if a cluster is detected in the prior, and a current classifier (CurC) based on current information alone is used if no prior cluster is detected. 175 temporal pairs of mammograms were used for evaluation. The search program detected 90.2% of the clusters on the priors with an average of 0.43 FPs/image. The CC identified 85% (l49/175) of the TP-TP pairs with 15 false matches within the 164 image pairs that had detected clusters. The TC achieved a test Az of 0.83 for the 164 pairs for classifying the clusters as malignant or benign. For the 11 clusters without detection on the prior, the test Az by the CurC was 0.72. The radiologist achieved an Az of 0.72 for both the 175 and the 164 temporal pairs.

Book Computer Aided Interval Change Analysis of Microcalifications on Management for Breast Cancer Detection

Download or read book Computer Aided Interval Change Analysis of Microcalifications on Management for Breast Cancer Detection written by and published by . This book was released on 2006 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this project is to develop a computer-aided diagnosis (CAD) system for automatic interval change analysis of microcalcification clusters on mammograms. Based on our regional registration method and a search program cluster candidates were detected within the local area on the prior. The cluster on the current image is then paired with the candi-dates to form true (TP-TP) or false (TP-FP) pairs and a correspondence classifier is designed to reduce the (TP-FP). A temporal classifier (TC) based on current and prior information is used if a cluster is detected in the prior, and a current classifier (CurC) based on current information alone is used if no prior cluster is detected. For the TC an LDA, SVM and NN were used. 175 temporal pairs of mammograms were used for evaluation. The registration stage identified 85% (1491175) of the TP-TP pairs with 15 false matches within the 164 image pairs that had detected clusters. The TC based on LDA, SVM and NN achieved a test Az of 0.83, 0.82, 0.84, respectively, for the 164 pairs for classifying the clusters as malignant or benign. For the II clusters without detection on the prior, the test Az by the CurC was 0.72. Four radiologists participated in pilot observer study using our CAD. The average Az in estimating the likelihood of malignancy was 0.70 without CAD and improved to 0.77 with CAD(p=O.04).

Book Computer aided Detection of Architectural Distortion in Prior Mammograms of Interval Cancer

Download or read book Computer aided Detection of Architectural Distortion in Prior Mammograms of Interval Cancer written by Shantanu Banik and published by Morgan & Claypool Publishers. This book was released on 2013-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Architectural distortion is an important and early sign of breast cancer, but because of its subtlety, it is a common cause of false-negative findings on screening mammograms. Screening mammograms obtained prior to the detection of cancer could contain subtle signs of early stages of breast cancer, in particular, architectural distortion. This book presents image processing and pattern recognition techniques to detect architectural distortion in prior mammograms of interval-cancer cases. The methods are based upon Gabor filters, phase portrait analysis, procedures for the analysis of the angular spread of power, fractal analysis, Laws' texture energy measures derived from geometrically transformed regions of interest (ROIs), and Haralick's texture features. With Gabor filters and phase-portrait analysis, 4,224 ROIs were automatically obtained from 106 prior mammograms of 56 interval-cancer cases, including 301 true-positive ROIs related to architectural distortion, and from 52 mammograms of 13 normal cases. For each ROI, the fractal dimension, the entropy of the angular spread of power, 10 Laws' texture energy measures, and Haralick's 14 texture features were computed. The areas under the receiver operating characteristic (ROC) curves obtained using the features selected by stepwise logistic regression and the leave-one-image-out method are 0.77 with the Bayesian classifier, 0.76 with Fisher linear discriminant analysis, and 0.79 with a neural network classifier. Free-response ROC analysis indicated sensitivities of 0.80 and 0.90 at 5.7 and 8.8 false positives (FPs) per image, respectively, with the Bayesian classifier and the leave-one-image-out method. The present study has demonstrated the ability to detect early signs of breast cancer 15 months ahead of the time of clinical diagnosis, on the average, for interval-cancer cases, with a sensitivity of 0.8 at 5.7 FP/image. The presented computer-aided detection techniques, dedicated to accurate detection and localization of architectural distortion, could lead to efficient detection of early and subtle signs of breast cancer at pre-mass-formation stages. Table of Contents: Introduction / Detection of Early Signs of Breast Cancer / Detection and Analysis of Oriented Patterns / Detection of Potential Sites of Architectural Distortion / Experimental Set Up and Datasets / Feature Selection and Pattern Classification / Analysis of Oriented Patterns Related to Architectural Distortion / Detection of Architectural Distortion in Prior Mammograms / Concluding Remarks

Book Digital Mammography

    Book Details:
  • Author : Nico Karssemeijer
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 9401153183
  • Pages : 520 pages

Download or read book Digital Mammography written by Nico Karssemeijer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: In June 1998 the Fourth International Workshop on Digital Mammography was held in Nijmegen, The Netherlands, where it was hosted by the department of Radiology of the University Hospital Nijmegen. This series of meetings was initiated at the 1993 SPIE Biomedical Image Processing Conference in San Jose, USA, where a number of sessions were entirely devoted to mammographic image analysis. At very successful subsequent workshops held in York, UK (1994) and Chicago, USA (1996), the scope of the conference was broadened, establishing a platform for presentation and discussion of new developments in digital mammog raphy. Topics that are addressed at these meetings are computer-aided diagnosis, image processing, detector development, system design, observer performance and clinical evaluation. The goal is to bring researchers from universities, breast cancer experts, and engineers together, to exchange information and present new scientific developments in this rapidly evolving field. This book contains all the scientific papers and posters presented at the work shop in Nijmegen. Contributions came from as many as 20 different countries and 190 participants attended the meeting. At a technical exhibit companies demon strated new products and work in progress. Abstracts of all papers were reviewed by members of the scientific committee. Many of the accepted papers had excellent quality, but due to limited space not all of them could be included as full papers in these proceedings. Papers that were rated high by the reviewers are included as long or short papers, others appear as extended abstracts in the last chapter.

Book Analysis of Interval Changes on Mammograms for Computer Aided Diagnosis

Download or read book Analysis of Interval Changes on Mammograms for Computer Aided Diagnosis written by and published by . This book was released on 1999 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this research is to develop a novel technique for computerized analysis of temporal differences between the most recent and previous mammograms of the same view in order to evaluate the usefulness of using interval change to distinguish between normal structures, benign masses, and malignant masses in computer-aided diagnosis (CAD). During this year, we have developed a multistage regional registration technique that combines global and local alignment procedures for identifying masses on temporal pairs of mammograms. In the first stage, the breast images from the current and previous mammograms were globally aligned by maximizing a mutual information measure. In the second stage a fan-shape search region based on polar coordinates was estimated on the previous mammogram. In the third stage a search for the best match between the lesion template from the current mammogram and a structure on the previous mammogram was carried out within the fan-shape region. We found that in 85% of the cases the corresponding regions on the previous and current mammogram were correctly identified. This technique can be useful for identification of corresponding lesions on temporal pairs of mammograms.

Book Developing Technologies for Early Detection of Breast Cancer

Download or read book Developing Technologies for Early Detection of Breast Cancer written by National Research Council and published by National Academies Press. This book was released on 2000-07-06 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: In November 1999, the Institute of Medicine, in consultation with the Commission on Life Sciences, the Commission on Physical Sciences, Mathematics, and Applications, and the Board on Science, Technology and Economic Policy launched a one year study on technologies for early detection of breast cancer. The committee was asked to examine technologies under development for early breast cancer detection, and to scrutinize the process of medical technology development, adoption, and dissemination. The committee is gathering information on these topics for its report in a number of ways, including two public workshops that bring in outside expertise. The first workshop on "Developing Technologies for Early Breast Cancer Detection" was held in Washington DC in February 2000. The content of the presentations at the workshop is summarized here. A second workshop, which will focus on the process of technology development and adoption, will be held in Washington, DC on June 19-20. A formal report on these topics, including conclusions and recommendations, will be prepared by the committee upon completion of the one-year study.

Book Non Linear Filters for Mammogram Enhancement

Download or read book Non Linear Filters for Mammogram Enhancement written by Vikrant Bhateja and published by Springer Nature. This book was released on 2019-11-02 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents non-linear image enhancement approaches to mammograms as a robust computer-aided analysis solution for the early detection of breast cancer, and provides a compendium of non-linear mammogram enhancement approaches: from the fundamentals to research challenges, practical implementations, validation, and advances in applications. The book includes a comprehensive discussion on breast cancer, mammography, breast anomalies, and computer-aided analysis of mammograms. It also addresses fundamental concepts of mammogram enhancement and associated challenges, and features a detailed review of various state-of-the-art approaches to the enhancement of mammographic images and emerging research gaps. Given its scope, the book offers a valuable asset for radiologists and medical experts (oncologists), as mammogram visualization can enhance the precision of their diagnostic analyses; and for researchers and engineers, as the analysis of non-linear filters is one of the most challenging research domains in image processing.

Book Mammography and Beyond

    Book Details:
  • Author : National Research Council
  • Publisher : National Academies Press
  • Release : 2001-07-23
  • ISBN : 0309171318
  • Pages : 311 pages

Download or read book Mammography and Beyond written by National Research Council and published by National Academies Press. This book was released on 2001-07-23 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year more than 180,000 new cases of breast cancer are diagnosed in women in the U.S. If cancer is detected when small and local, treatment options are less dangerous, intrusive, and costly-and more likely to lead to a cure. Yet those simple facts belie the complexity of developing and disseminating acceptable techniques for breast cancer diagnosis. Even the most exciting new technologies remain clouded with uncertainty. Mammography and Beyond provides a comprehensive and up-to-date perspective on the state of breast cancer screening and diagnosis and recommends steps for developing the most reliable breast cancer detection methods possible. This book reviews the dramatic expansion of breast cancer awareness and screening, examining the capabilities and limitations of current and emerging technologies for breast cancer detection and their effectiveness at actually reducing deaths. The committee discusses issues including national policy toward breast cancer detection, roles of public and private agencies, problems in determining the success of a technique, availability of detection methods to specific populations of women, women's experience during the detection process, cost-benefit analyses, and more. Examining current practices and specifying research and other needs, Mammography and Beyond will be an indispensable resource to policy makers, public health officials, medical practitioners, researchers, women's health advocates, and concerned women and their families.

Book Digital Mammography

    Book Details:
  • Author : Etta D. Pisano
  • Publisher : Lippincott Williams & Wilkins
  • Release : 2004
  • ISBN : 0781741424
  • Pages : 24 pages

Download or read book Digital Mammography written by Etta D. Pisano and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bogen er en grundlæggende lærebog om digital mammografi, hvori digital mammografi og traditionel mammografi også sammenlignes i forhold til screening, diagnoser og radiografisk billedteknik. Der er en komplet billedsamling af cases indenfor digital mammografi.

Book Breast Imaging

    Book Details:
  • Author : Christoph I. Lee
  • Publisher : Oxford University Press
  • Release : 2018
  • ISBN : 0190270268
  • Pages : 545 pages

Download or read book Breast Imaging written by Christoph I. Lee and published by Oxford University Press. This book was released on 2018 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast Imaging presents a comprehensive review of the subject matter commonly encountered by practicing radiologists and radiology residents in training. This volume includes succinct overviews of breast cancer epidemiology, screening, staging, and treatment; overviews of all imaging modalities including mammography, tomosynthesis, ultrasound, and MRI; step-by-step approaches for image-guided breast interventions; and high-yield chapters organized by specific imaging finding seen on mammography, tomosynthesis, ultrasound, and MRI. Part of the Rotations in Radiology series, this book offers a guided approach to breast imaging interpretation and techniques, highlighting the nuances necessary to arrive at the best diagnosis and management. Each chapter contains a targeted discussion of an imaging finding which reviews the anatomy and physiology, distinguishing features, imaging techniques, differential diagnosis, clinical issues, key points, and further reading. Breast Imaging is a must-read for residents and practicing radiologists seeking a foundation for the essential knowledge base in breast imaging.

Book Improving Breast Imaging Quality Standards

Download or read book Improving Breast Imaging Quality Standards written by National Research Council and published by National Academies Press. This book was released on 2005-09-27 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammography is an important tool for detecting breast cancer at an early stage. When coupled with appropriate treatment, early detection can reduce breast cancer mortality. At the request of Congress, the Food and Drug Administration (FDA) commissioned a study to examine the current practice of mammography and breast cancer detection, with a focus on the FDA's oversight via the Mammography Quality Standards Act (MQSA), to identify areas in need of improvement. Enacted in 1993, MQSA provides a general framework for ensuring national quality standards in facilities performing screening mammography, requires that each mammography facility be accredited and certified, and mandates that facilities will undergo annual inspections. This book recommends strategies for achieving continued progress in assuring mammography quality, including changes to MQSA regulation, as well as approaches that do not fall within the purview of MQSA. Specifically, this book provides recommendations aimed at improving mammography interpretation; revising MQSA regulations, inspections, and enforcement; ensuring an adequate workforce for breast cancer screening and diagnosis; and improving breast imaging quality beyond mammography.

Book Automated Analysis for Microcalcifications in High Resolution Digital Mammograms

Download or read book Automated Analysis for Microcalcifications in High Resolution Digital Mammograms written by and published by . This book was released on 1993 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digital mammography offers the promise of significant advances in early detection of breast cancer. Our overall goal is to design a digital system which improves upon every aspect of current mammography technology: the x-ray source, detector, visual presentation of the mammogram and computer-aided diagnosis capabilities. This paper will discuss one part of our whole-system approach -- the development of a computer algorithm using gray-scale morphology to automatically analyze and flag microcalcifications in digital mammograms in hopes of reducing the current percentage of false-negative diagnoses, which is estimated at 20%. The mammograms used for developing this ''mammographers assistant'' are film mammograms which we have digitized at either 70 [mu]m or 35 [mu]m per pixel resolution with 4096 (12 bits) of gray level per pixel. For each potential microcalcification detected in these images, we compute a number of features in order to distinguish between the different kinds of objects detected.

Book Cancer

    Book Details:
  • Author : Uday M. Pujare
  • Publisher :
  • Release : 1980
  • ISBN :
  • Pages : 212 pages

Download or read book Cancer written by Uday M. Pujare and published by . This book was released on 1980 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Detection of Breast Cancer Microcalcifications in Mammograms

Download or read book Detection of Breast Cancer Microcalcifications in Mammograms written by Ayman Abubaker and published by LAP Lambert Academic Publishing. This book was released on 2012-05 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cancer is the second leading cause of cancer deaths in women, exceeded only by lung cancer. Earlier detection, through non-invasive mammography scanning is extremely important for reducing the death rates from breast cancer. In this book we introduce an automated Computer Aided Diagnosis (CAD) system that can accurately detect cancer cells at early stages and reduce the workload of radiologists. The CAD system integrates image processing and machine learning technologies to simulate the way radiologists detect Microcalcifications in mammograms. The CAD system is tested on Benchmark data sets and reliable performance is achieved. This book will be useful for professionals interested in medical imaging technologies and also the development of CAD systems. It will be also relevant to academics and research students dealing with imaging, machine learning and medical research.

Book Detection of Breast Cancer Microcalcifications in Digitized Mammograms

Download or read book Detection of Breast Cancer Microcalcifications in Digitized Mammograms written by Husam E. I. Al-Osta and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammography is used to aid early detection and diagnosis systems. It takes an x-ray image of the breast and can provide a second opinion for radiologists. The earlier detection is made, the better treatment works. Digital mammograms are dealt with by Computer Aided Diagnosis (CAD) systems that can detect and analyze abnormalities in a mammogram. The purpose of this study is to investigate how to categories cropped regions of interest (ROI) from digital mammogram images into two classes; normal and abnormal regions (which contain microcalcifications). The work proposed in this thesis is divided into three stages to provide a concept system for classification between normal and abnormal cases. The first stage is the Segmentation Process, which applies thresholding filters to separate the abnormal objects (foreground) from the breast tissue (background). Moreover, this study has been carried out on mammogram images and mainly on cropped ROI images from different sizes that represent individual microcalcification and ROI that represent a cluster of microcalcifications. The second stage in this thesis is feature extraction. This stage makes use of the segmented ROI images to extract characteristic features that would help in identifying regions of interest. The wavelet transform has been utilized for this process as it provides a variety of features that could be examined in future studies. The third and final stage is classification, where machine learning is applied to be able to distinguish between normal ROI images and ROI images that may contain microcalcifications. The result indicated was that by combining wavelet transform and SVM we can distinguish between regions with normal breast tissue and regions that include microcalcifications.

Book State of the Art in Digital Mammographic Image Analysis

Download or read book State of the Art in Digital Mammographic Image Analysis written by K. W. Bowyer and published by World Scientific. This book was released on 1994 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed assessment of the state of the art in automated techniques for the analysis of digital mammogram images. Topics covered include a variety of approaches for image processing and pattern recognition aimed at assisting the physician in the task of detecting tumors from evidence in mammogram images. The chapters are written by recognized experts in the field and are revised versions of papers selected from those presented at the “First International Workshop on Mammogram Image Analysis” held in San Jose as part of the 1993 Biomedical Image Processing conference.