Download or read book Computer Aided Design and Characterization of Optimal Biomorphic Scaffolds for Tissue Engineering written by Srinivasan Rajagopalan and published by . This book was released on 2005 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Characterisation and Design of Tissue Scaffolds written by Paul Tomlins and published by Elsevier. This book was released on 2015-10-30 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Characterisation and Design of Tissue Scaffolds offers scientists a useful guide on the characterization of tissue scaffolds, detailing what needs to be measured and why, how such measurements can be made, and addressing industrially important issues. Part one provides readers with information on the fundamental considerations in the characterization of tissue scaffolds, while other sections detail how to prepare tissue scaffolds, discuss techniques in characterization, and present practical considerations for manufacturers. Summarizes concepts and current practice in the characterization and design of tissue scaffolds Discusses design and preparation of scaffolds Details how to prepare tissue scaffolds, discusses techniques in characterization, and presents practical considerations for manufacturers
Download or read book Characterization of Biomaterials written by Julia Will and published by Elsevier Inc. Chapters. This book was released on 2013-03-12 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to enhance the application potential of scaffolds in tissue engineering, comprehensive characterization of scaffold micro- and macro-structure, porosity, permeability and mechanical properties are required. In addition, before in vivo studies can be carried out, a complete assessment of the in vitro behavior of scaffolds, e.g. in selected cell culture studies, is required. The present chapter revises the wide range of methods applied to characterize scaffolds and emphasizes the need for a combination of different characterization techniques for understanding scaffold performance required for successful bone regeneration.
Download or read book MICCAI 2005 written by James Duncan and published by Springer Science & Business Media. This book was released on 2005-10-11 with total page 981 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-volume set LNCS 3749 and LNCS 3750 constitutes the refereed proceedings of the 8th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2005, held in Palm Springs, CA, USA, in October 2005. Based on rigorous peer reviews the program committee selected 237 carefully revised full papers from 632 submissions for presentation in two volumes. The first volume includes all the contributions related to image analysis and validation, vascular image segmentation, image registration, diffusion tensor image analysis, image segmentation and analysis, clinical applications - validation, imaging systems - visualization, computer assisted diagnosis, cellular and molecular image analysis, physically-based modeling, robotics and intervention, medical image computing for clinical applications, and biological imaging - simulation and modeling. The second volume collects the papers related to robotics, image-guided surgery and interventions, image registration, medical image computing , structural and functional brain analysis, model-based image analysis, image-guided intervention: simulation, modeling and display, and image segmentation and analysis.
Download or read book Computer Aided Tissue Engineering written by Alberto Rainer and published by . This book was released on 2021 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Medical Image Computing and Computer Assisted Intervention MICCAI 2005 written by James Duncan and published by Springer. This book was released on 2005-09-27 with total page 981 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomimetic Design and Fabrication of Tissue Scaffolds written by Binil Starly and published by VDM Publishing. This book was released on 2007 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Development and Selection of Porous Scaffolds Using Computer Aided Tissue Engineering written by Pradip Dutta and published by . This book was released on 2012-09-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of their biocompatibility and desirable mechanical properties, chitosan along with other materials like hydroxyapatite and polycaprolactone have been studied and used as tor create engineered matrices 'scaffolds' for artificially growing tissue for medical uses in tissue and organ repair. This new monograph in the ASME-Momentum Press series on Biomedical and Nanomedical Technologies, will discuss the latest uses of computer-aided technologies for designing such scaffolds and performing characterization to create desired mechanical and physical properties.
Download or read book Medical Image Computing and Computer Assisted Intervention MICCAI 2006 written by Rasmus Larsen and published by Springer Science & Business Media. This book was released on 2006-09-21 with total page 1017 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-volume set LNCS 4190 and LNCS 4191 constitute the refereed proceedings of the 9th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2006. The program committee carefully selected 39 revised full papers and 193 revised poster papers for presentation in two volumes. This second volume collects 118 papers related to segmentation, validation and quantitative image analysis, brain image processing, and much more.
Download or read book Design Fabrication and Characterization of Biodegradable Scaffolds for Tissue Engineering and Regenerative Medicine Applications written by Muhammad Anwaar Nazeer and published by . This book was released on 2018 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Development and Characterization of PLGA 8515 Scaffold for Tissue Engineering Applications written by Josee Karine Perron and published by . This book was released on 2006 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This study reports the design, development, and characterization of 85/15 poly (dl-lactide-co-glycolide) acid (PLGA 85/15) scaffolds for tissue engineering applications. In this respect the effects of different processing parameters on the PLGA 85/15 scaffold's physical and mechanical properties were investigated. Porous PLGA 85/15 scaffolds were prepared using a gas foaming/salt leaching technique. The processing parameters under examination included gas saturation pressure, gas saturation time, and NaCl/polymer mass ratio. The physical properties of the scaffold considered were the density, the porosity, the average pore size, and the pore density. The mechanical property studied was the Young's modulus in compression. The results demonstrated that all the processing parameters worked in concert to produce a scaffold with a high level of interconnectivity. From the parameteric study, key processing parameters were identified and selected parameters led to optimal physical and mechanical properties of the scaffold. The experimental results obtained from the mechanical properties of scaffolds were compared with a theoretical model from Gibson and Ashby relating the scaffold's mechanical properties to the density. The predicted elastic responses of opened pores structure from the theoretical model showed agreement with the experimental results. Subsequently, the effect of the optimized PLGA 85/15 scaffolds on the cell growth and the cell viability of the human promyelocytic leukemia cell line (HL-60) were reported. The investigation showed that the cell growth and viability were not impaired by the presence of PLGA 85/15 scaffolds for the time period under investigation. Finally, the effects of different degradation media on the optimized PLGA 85/15 scaffold's physical and mechanical properties were also elucidated. The three different media were distilled water (dH2O), a phosphate buffered saline (PBS) solution, and HL-60 cells. In general, the average macropore size and the average molecular weight decreased as the degradation time increased in each medium. However, the scaffolds maintained mechanical and structural integrity throughout the study in all three media over the degradation period studied. Overall, PBS solution most strongly affected physical and mechanical properties, followed by dH2O and HL-60 cells. The distinct variations of the scaffold's properties using different media, demonstrated the importance of carefully selecting the medium to perform in vitro studies. The medium must replicate the actual environment where the scaffold would be used, in order to represent accurately the changes in properties that the scaffold would be undergoing.
Download or read book Novel Microsphere Based Spiral Scaffolds for Bone Tissue Engineering written by Mayur Thakore and published by . This book was released on 2007 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Automated Design of Trabecular Structures written by Ettore Ramin and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Additive manufacturing technologies are enabling newfound degrees of geometrical complexity to be realised, particularly with regards to internal structures. All of these manufacturing technologies are dependant on their prior design in an appropriate electronic form, either by reverse engineering, or, primarily, by computer-aided design. Within these emerging applications is the design of scaffolds with an intricate and controlled internal structure for bone tissue engineering. There is a consensus that ideal bone scaffold geometry is evident in biological trabecular structures. In their most basic topological form, these structures consist of the non-linear distribution of irregular interconnecting rods and plates of different size and shape. Complex and irregular architectures can be realised by several scaffold manufacturingtechniques, but with little or no control over the main features of the internal geometry, suchas size, shape and interconnectivity of each individual element. The combined use ofcomputer aided design systems and additive manufacturing techniques allows a high degreeof control over these parameters with few limitations in terms of achievable complexity. However, the design of irregular and intricate trabecular networks in computer aided designsystems is extremely time-consuming since manually modelling an extraordinary number ofdifferent rods and plates, all with different parameters, may require several days to design anindividual scaffold structure. In an attempt to address these difficulties, several otherresearch efforts in this domain have largely focussed on techniques which result in designswhich comprise of relatively regular and primitive shapes and do not represent the level ofcomplexity seen biologically. Detailed descriptions of these methods are covered in chapter 1. An automated design methodology for trabecular structures is proposed by this research to overcome these limitations. This approach involves the investigation of novel software algorithms, which are able to interact with a conventional computer aided design programand permit the automated design of geometrical elements in the form of rods, each with adifferent size and shape. The methodology is described in chapter 2 and is tested in chapter3. Applications of this methodology in anatomical designs are covered in chapter 4. Nevertheless, complex designed rod networks may still present very different properties compared to trabecular bone geometries due to a lack detailed information available which explicitly detail their geometry. The lack of detailed quantitative descriptions of trabecular bone geometries may compromise the validity of any design methodology, irrespective of automation and efficiency. Although flexibility of a design methodology is beneficial, this may be rendered inadequate when insufficient quantitative data is known of the target structure. In this work a novel analysis methodology is proposed in chapter 5, which may provide a significant contribution toward the characterisation and quantification of target geometries, with particular focus on trabecular bone structures. This analysis methodology can be used either to evaluate existing design techniques or to drive the development of new bio-mimetic design techniques. This work then progresses to a newly derived bio-mimetic automated design technique, driven by the newly produced quantitative data on trabecular bone geometries. This advanced design methodology has been developed and tested in chapter 6. This has demonstrated the validity of the technique and realised a significant stage of development inthe context and scope of this work.
Download or read book Biomimetic Design and Fabrication of Tissue Engineered Scaffolds Using Computer Aided Tissue Engineering written by Binil Starly and published by . This book was released on 2006 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Computer Aided Tissue Engineering written by Michael A.K. Liebschner and published by Humana Press. This book was released on 2012-06-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent revolution in the biological sciences and bioengineering, along with the advancements of modern design and manufacturing, biomaterials, biology, and biomedicine, have brought about the new field of computer-aided tissue engineering. Advances in this fascinating new area of study encompass broad applications in large-scale tissue engineering fabrication, artificial organs, orthopaedic implants, and biological chips. Computer-Aided Tissue Engineering highlights the interdisciplinary nature of this topic and reviews the current state of computer-aided three-dimensional tissue modeling, tissue classification, and tissue fabrication and implantation. Particular focus is placed on rapid prototyping and direct digital fabrication for cell and organs, construction of tissue analogs, and precursors to 3D tissue scaffolds. Written for the highly successful Methods in Molecular BiologyTM series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Current and practical, Computer-Aided Tissue Engineering provides a coherent framework for researchers interested in these vital technologies and for clinicians who plan to implement them.
Download or read book High Value Manufacturing Advanced Research in Virtual and Rapid Prototyping written by Maria K. Todd and published by CRC Press. This book was released on 2013-09-16 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: High Value Manufacturing is the result of the 6th International Conference on Advanced Research in Virtual and Rapid Prototyping, held in Leiria, Portugal, October 2013. It contains current contributions to the field of virtual and rapid prototyping (V&RP) and is also focused on promoting better links between industry and academia. This volume
Download or read book 3D Printing and Biofabrication written by Aleksandr Ovsianikov and published by Springer. This book was released on 2018-06-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an in-depth introduction to 3D printing and biofabrication and covers the recent advances in additive manufacturing for tissue engineering. The book is divided into two parts, the first part on 3D printing discusses conventional approaches in additive manufacturing aimed at fabrication of structures, which are seeded with cells in a subsequent step. The second part on biofabrication presents processes which integrate living cells into the fabrication process.
