Download or read book Computational Methods of Modeling Vascular Geometry and Tracking Pulmonary Motion from Medical Images written by Guanglei Xiong and published by Stanford University. This book was released on 2011 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern anatomical medical imaging technologies, such as computed tomography and magnetic resonance, capture structures of the human body in exquisite detail. Computational anatomy is a developing discipline to extract and characterize the anatomy from images. Unfortunately, anatomical images do not reveal the functional behavior. Computational physiology shows great potential to link the structure-function relationship by considering both the anatomical information and the physical governing laws. The simulated physiology can be used to assess physiological states, and more importantly predict the outcomes of interventions. On the other hand, advances in the functional imaging techniques provide measured physiology information and should be utilized together with computational physiology. In the theme of computational anatomy and physiology, this dissertation describes computational methods of modeling vascular geometry for image-based blood flow computation and tracking pulmonary motion for image-guided radiation therapy. Blood flow computation is a useful tool to quantify in vivo hemodynamics. The essential first step is to model vascular geometry from medical imaging data. I have developed a new workflow for this task. The geometric model construction is based on 3D image segmentation and geometric processing. To represent the topology of the constructed model, I have developed a novel centerline extraction method. To account for compliant vessels, methods to assign spatially-varying mechanical properties of the vessel wall are also developed. The workflow greatly increases the modeling efficiency. The combination of the patient-specific geometry and wall deformation can enhance the fidelity of blood flow simulation. Image-based blood flow computation also holds great promise for device design and surgical procedure evaluation. Next, I have developed novel virtual intervention methods to deploy stents or stent grafts to patient-specific pre-operative geometric models constructed from medical images. These methods enable prospective model construction and may be used to evaluate the outcomes of alternative treatment options. Respiratory motion is closely related to the physiology of the lung. Finally, I have developed a novel framework to track patient-specific pulmonary motion from 4D computed tomography images. A large set of vascular junction structures in the lung are identified as landmarks and tracked to obtain their motion trajectories. This framework can provide accurate motion information, which is important in radiation therapy to reduce healthy tissue irradiation while allowing target dose escalation. This work demonstrates the importance of the geometry and motion modeling tools in computational anatomy and physiology. Accurate physiological information, whether simulated or measured, will benefit the diagnosis and treatment of various diseases.
Download or read book Computational Methods of Modeling Vascular Geometry and Tracking Pulmonary Motion from Medical Images written by Guanglei Xiong and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern anatomical medical imaging technologies, such as computed tomography and magnetic resonance, capture structures of the human body in exquisite detail. Computational anatomy is a developing discipline to extract and characterize the anatomy from images. Unfortunately, anatomical images do not reveal the functional behavior. Computational physiology shows great potential to link the structure-function relationship by considering both the anatomical information and the physical governing laws. The simulated physiology can be used to assess physiological states, and more importantly predict the outcomes of interventions. On the other hand, advances in the functional imaging techniques provide measured physiology information and should be utilized together with computational physiology. In the theme of computational anatomy and physiology, this dissertation describes computational methods of modeling vascular geometry for image-based blood flow computation and tracking pulmonary motion for image-guided radiation therapy. Blood flow computation is a useful tool to quantify in vivo hemodynamics. The essential first step is to model vascular geometry from medical imaging data. I have developed a new workflow for this task. The geometric model construction is based on 3D image segmentation and geometric processing. To represent the topology of the constructed model, I have developed a novel centerline extraction method. To account for compliant vessels, methods to assign spatially-varying mechanical properties of the vessel wall are also developed. The workflow greatly increases the modeling efficiency. The combination of the patient-specific geometry and wall deformation can enhance the fidelity of blood flow simulation. Image-based blood flow computation also holds great promise for device design and surgical procedure evaluation. Next, I have developed novel virtual intervention methods to deploy stents or stent grafts to patient-specific pre-operative geometric models constructed from medical images. These methods enable prospective model construction and may be used to evaluate the outcomes of alternative treatment options. Respiratory motion is closely related to the physiology of the lung. Finally, I have developed a novel framework to track patient-specific pulmonary motion from 4D computed tomography images. A large set of vascular junction structures in the lung are identified as landmarks and tracked to obtain their motion trajectories. This framework can provide accurate motion information, which is important in radiation therapy to reduce healthy tissue irradiation while allowing target dose escalation. This work demonstrates the importance of the geometry and motion modeling tools in computational anatomy and physiology. Accurate physiological information, whether simulated or measured, will benefit the diagnosis and treatment of various diseases.
Download or read book Image Based Computational Modeling of the Human Circulatory and Pulmonary Systems written by Krishnan B. Chandran and published by Springer Science & Business Media. This book was released on 2010-11-18 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Image-Based Computational Modeling of the Human Circulatory and Pulmonary Systems provides an overview of the current modeling methods and applications enhancing interventional treatments and computer-aided surgery. A detailed description of the techniques behind image acquisition, processing and three-dimensional reconstruction are included. Techniques for the computational simulation of solid and fluid mechanics and structure interaction are also discussed, in addition to various cardiovascular and pulmonary applications. Engineers and researchers involved with image processing and computational modeling of human organ systems will find this a valuable reference.
Download or read book Studying Computational Methods for Biomedical Geometry Extraction and Patient Specific Hemodynamics written by Zhiqiang Wang (Computer scientist) and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the development of medical imaging and numerical simulation techniques, image based Patient Specific Computational Hemodynamics (PSCH) has become a powerful approach to non-invasively quantify vascular fluid mechanics in human arteries. However, most existing PSCH methods are currently impractical for real clinic applications due to time consuming computation. In clinic applications, an image based efficient PSCH approach is needed to offer Patient-Specific diagnosis information in a timely manner and also to make large population studies possible. Without these studies, the correlation between Patient-Specific clinical symptom and hemodynamic patterns cannot be assessed. In the image based PSCH processing procedure, there are three main parts responsible for the bulk of the computation. The first one is obtaining the anatomic geometry. The second is converting the geometry into a suitable mesh or grid for simulation. The third hotspot is the large numbers of calculations in hemodynamics simulation.To address above problems, in this thesis, some efficient algorithms have been proposed to speed up image based PSCH computations.First, a fully parallel numerical method is proposed to quickly extract anatomical geometry from medical images. This method can efficiently solve the level set equations of active contour based on Lattice Boltzmann model (LBM) for image segmentation. And a parallel distance field regularization algorithm is integrated to the LBM computing scheme to keep computation stable. This approach avoids external regularization which has been a major impediment to direct parallelization of level set evolution with LBM. It allows the whole computing process to be efficiently executed on Graphics Processing Unit (GPU). Further, this method can be incorporated with different image features for various image segmentation tasks.Second, a new method is proposed by utilizing fluid features, particularly the mean flow intensity, to extract the blood flow field in a target vessel from 4D flow MRI images which encode blood velocity information in vessels. This approach is computational efficient and robust to blood flow changes in a cardiac cycle even in relatively small arteries. The extracted velocity field can be used as inlet and outlet conditions facilitating the hemodynamics simulation and for evaluating simulation result. Moreover, the target artery wall deformation factors at a few spatial locations of the artery and time steps in one cardiac cycle can be estimated. These factors enable the generation of high quality and deforming artery walls by morphing the wall acquired from accurate but static Time of Flight (TOF) MRI images. The dynamic artery wall benefits blood flow visualization tasks and also has potential to be used as moving boundary for hemodynamic simulations.Third, after image segmentation, the anatomical geometry is implicitly represented by zero level set of distance field. Based on segmentation result, a method is first proposed to directly generate simulation grids for Volumetric Lattice Boltzmann Method (VLBM) based hemodynamic simulation. There is no surface reconstruction and mesh generation needed. Therefore, it can avoid extra computational cost and inaccuracy during the two transforms: from volume to mesh, then from mesh to volume grids. Further, surface normal direction at artery wall can also be directly estimated to calculate Wall Shear Stress (WSS) .Finally, VLBM has been GPU accelerated to simulate hemodynamics in human arteries by using a uniform computing scheme for both fluid and boundary grids. For traditional computational fluid simulation method, its boundary conditions have to be separately performed over boundary nodes from fluid nodes, where large number of branching operations are inefficient for GPU parallel computation due to its Single Instruction Multiple Data (SIMD) architecture. For complicated biomechanics structure, this situation would be worse, as there are a lot of boundary cells in the computation domain. The proposed parallel VLBM implementation does not need to distinguish fluid and boundary cells in the computation so that branching is minimized and the GPU kernel execution is accelerated.
Download or read book Medical Image Computing and Computer Assisted Intervention MICCAI 2009 written by Guang-Zhong Yang and published by Springer Science & Business Media. This book was released on 2009-09-07 with total page 1078 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-volume set LNCS 5761 and LNCS 5762 constitute the refereed proceedings of the 12th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2009, held in London, UK, in September 2009. Based on rigorous peer reviews, the program committee carefully selected 259 revised papers from 804 submissions for presentation in two volumes. The first volume includes 125 papers divided in topical sections on cardiovascular image guided intervention and robotics; surgical navigation and tissue interaction; intra-operative imaging and endoscopic navigation; motion modelling and image formation; image registration; modelling and segmentation; image segmentation and classification; segmentation and atlas based techniques; neuroimage analysis; surgical navigation and robotics; image registration; and neuroimage analysis: structure and function.
Download or read book Topics in Medical Image Processing and Computational Vision written by Joao Manuel R.S. Tavares and published by Springer Science & Business Media. This book was released on 2013-03-27 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sixteen chapters included in this book were written by invited experts of international recognition and address important issues in Medical Image Processing and Computational Vision, including: Object Recognition, Object Detection, Object Tracking, Pose Estimation, Facial Expression Recognition, Image Retrieval, Data Mining, Automatic Video Understanding and Management, Edges Detection, Image Segmentation, Modelling and Simulation, Medical thermography, Database Systems, Synthetic Aperture Radar and Satellite Imagery. Different applications are addressed and described throughout the book, comprising: Object Recognition and Tracking, Facial Expression Recognition, Image Database, Plant Disease Classification, Video Understanding and Management, Image Processing, Image Segmentation, Bio-structure Modelling and Simulation, Medical Imaging, Image Classification, Medical Diagnosis, Urban Areas Classification, Land Map Generation. The book brings together the current state-of-the-art in the various multi-disciplinary solutions for Medical Image Processing and Computational Vision, including research, techniques, applications and new trends contributing to the development of the related areas.
Download or read book Medical Image Computing and Computer Assisted Intervention MICCAI 2008 written by Dimitris N. Metaxas and published by Springer Science & Business Media. This book was released on 2008 with total page 1161 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Medical Image Processing and Analysis written by Isaac Bankman and published by Elsevier. This book was released on 2008-12-24 with total page 1009 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Medical Image Processing and Analysis is a comprehensive compilation of concepts and techniques used for processing and analyzing medical images after they have been generated or digitized. The Handbook is organized into six sections that relate to the main functions: enhancement, segmentation, quantification, registration, visualization, and compression, storage and communication.The second edition is extensively revised and updated throughout, reflecting new technology and research, and includes new chapters on: higher order statistics for tissue segmentation; tumor growth modeling in oncological image analysis; analysis of cell nuclear features in fluorescence microscopy images; imaging and communication in medical and public health informatics; and dynamic mammogram retrieval from web-based image libraries.For those looking to explore advanced concepts and access essential information, this second edition of Handbook of Medical Image Processing and Analysis is an invaluable resource. It remains the most complete single volume reference for biomedical engineers, researchers, professionals and those working in medical imaging and medical image processing.Dr. Isaac N. Bankman is the supervisor of a group that specializes on imaging, laser and sensor systems, modeling, algorithms and testing at the Johns Hopkins University Applied Physics Laboratory. He received his BSc degree in Electrical Engineering from Bogazici University, Turkey, in 1977, the MSc degree in Electronics from University of Wales, Britain, in 1979, and a PhD in Biomedical Engineering from the Israel Institute of Technology, Israel, in 1985. He is a member of SPIE. Includes contributions from internationally renowned authors from leading institutions NEW! 35 of 56 chapters have been revised and updated. Additionally, five new chapters have been added on important topics incluling Nonlinear 3D Boundary Detection, Adaptive Algorithms for Cancer Cytological Diagnosis, Dynamic Mammogram Retrieval from Web-Based Image Libraries, Imaging and Communication in Health Informatics and Tumor Growth Modeling in Oncological Image Analysis. Provides a complete collection of algorithms in computer processing of medical images Contains over 60 pages of stunning, four-color images
Download or read book Medical Image Computing and Computer Assisted Intervention MICCAI 2005 written by James Duncan and published by Springer. This book was released on 2005-09-27 with total page 1057 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-volume set LNCS 3749 and LNCS 3750 constitutes the refereed proceedings of the 8th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2005, held in Palm Springs, CA, USA, in October 2005. Based on rigorous peer reviews the program committee selected 237 carefully revised full papers from 632 submissions for presentation in two volumes. The first volume includes all the contributions related to image analysis and validation, vascular image segmentation, image registration, diffusion tensor image analysis, image segmentation and analysis, clinical applications - validation, imaging systems - visualization, computer assisted diagnosis, cellular and molecular image analysis, physically-based modeling, robotics and intervention, medical image computing for clinical applications, and biological imaging - simulation and modeling. The second volume collects the papers related to robotics, image-guided surgery and interventions, image registration, medical image computing, structural and functional brain analysis, model-based image analysis, image-guided intervention: simulation, modeling and display, and image segmentation and analysis.
Download or read book Medical Image Computing and Computer Assisted Intervention MICCAI 2004 written by Christian Barillot and published by Springer. This book was released on 2011-04-05 with total page 1152 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 7th International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI 2004, was held in Saint-Malo, Brittany, France at the “Palais du Grand Large” conference center, September 26–29, 2004. The p- posaltohostMICCAI2004wasstronglyencouragedandsupportedbyIRISA, Rennes. IRISA is a publicly funded national research laboratory with a sta? of 370,including150full-timeresearchscientistsorteachingresearchscientistsand 115 postgraduate students. INRIA, the CNRS, and the University of Rennes 1 are all partners in this mixed research unit, and all three organizations were helpful in supporting MICCAI. MICCAI has become a premier international conference with in-depth - pers on the multidisciplinary ?elds of medical image computing, comput- assisted intervention and medical robotics. The conference brings together cl- icians, biological scientists, computer scientists, engineers, physicists and other researchers and o?ers them a forum to exchange ideas in these exciting and rapidly growing ?elds. The impact of MICCAI increases each year and the quality and quantity of submitted papers this year was very impressive. We received a record 516 full submissions (8 pages in length) and 101 short communications (2 pages) from 36 di?erent countries and 5 continents (see ?gures below). All submissions were reviewed by up to 4 external reviewers from the Scienti?c Review C- mittee and a primary reviewer from the Program Committee. All reviews were then considered by the MICCAI 2004 Program Committee, resulting in the acceptance of 235 full papers and 33 short communications.
Download or read book Research Awards Index written by and published by . This book was released on 1978 with total page 1384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Subject Index of Current Research Grants and Contracts Administered by the National Heart Lung and Blood Institute written by National Heart, Lung, and Blood Institute and published by . This book was released on 1978 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Digital Orthopedics written by Guoxian Pei and published by Springer. This book was released on 2019-03-14 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses all aspects of digital techniques in orthopedics, from development of the core principles to imaging techniques, computer-aided design, reverse engineering and their applications. It illustrates the successful applications in accurate operation using 3-D reconstruction and applied digital techniques. All illustrations and tables were meticulously selected and are easy to understand. The book was written for all doctors and researchers who work in the fields of orthopedics, CAD/CAM and anatomy. Above all, surgeons, physiatrists, radiologists, and engineers in image processing and orthopedics will find it a valuable resource.
Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1975 with total page 1224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pulmonary Functional Imaging written by Yoshiharu Ohno and published by Springer Nature. This book was released on 2020-12-11 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the basics of pulmonary functional imaging using new CT and MR techniques and describes the clinical applications of these techniques in detail. The intention is to equip readers with a full understanding of pulmonary functional imaging that will allow optimal application of all relevant techniques in the assessment of a variety of diseases, including COPD, asthma, cystic fibrosis, pulmonary thromboembolism, pulmonary hypertension, lung cancer and pulmonary nodule. Pulmonary functional imaging has been promoted as a research and diagnostic tool that has the capability to overcome the limitations of morphological assessments as well as functional evaluation based on traditional nuclear medicine studies. The recent advances in CT and MRI and in medical image processing and analysis have given further impetus to pulmonary functional imaging and provide the basis for future expansion of its use in clinical applications. In documenting the utility of state-of-the-art pulmonary functional imaging in diagnostic radiology and pulmonary medicine, this book will be of high value for chest radiologists, pulmonologists, pulmonary surgeons, and radiation technologists.
Download or read book Applied Mechanics Reviews written by and published by . This book was released on 1993 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2098 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
