Download or read book Computational and Experimental Studies in Alzheimer s Disease written by Kunal Bhattacharya and published by . This book was released on 2024-03-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book compiles the recent advances in computational and experimental modeling to screen and manage Alzheimer's disease. The book discusses how computer-aided drug design approaches reduce costs and increase biological test efficiency.
Download or read book Computational and Experimental Studies in Alzheimer s Disease written by Kunal Bhattacharya and published by CRC Press. This book was released on 2024-03-29 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book compiles the recent advances in computational and experimental modelling to screen and manage Alzheimer’s disease. It covers basic etiopathology and various in vitro and in vivo strategies of disease intervention. The book discusses how computer-aided drug design approaches reduce costs and increase biological test efficiency. It reviews the screening for anti-Alzheimer drugs and biomarker analysis of disease inhibitors. The book also explores mechanistic aspects of neurodegeneration and the use of natural products as therapeutics for Alzheimer’s disease. Key features: Elaborates on the computational modelling of protein target inhibitors as anti-Alzheimer’s agents Explains the role of phytomolecules and natural products in Alzheimer’s therapy Reviews preclinical ways to assess drugs focusing on Alzheimer’s disease Covers biomarker analysis for Alzheimer’s disease Discusses the onset and progression of Alzheimer’s disease The book is meant for professionals, researchers, and students of neuroscience, psychology, and computational neurosciences.
Download or read book Alzheimer s Disease Biology Biophysics And Computational Models written by Don Kulasiri and published by World Scientific. This book was released on 2022-01-06 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease (AD) is the leading cause of dementia and, unfortunately, remains incurable. The social, emotional and financial implications of AD are immeasurable, and about 47 million people worldwide are affected by AD or other forms of dementia. As lifespans are improved by healthcare systems worldwide, age-associated neurodegenerative diseases are imposing an increasing challenge to science. It is becoming imperative for us to understand the causes of these diseases, AD in particular, at molecular and cellular levels. Starting with the broader picture from a biological perspective, this book takes the reader through fascinating dynamics within and outside of neurons in the brain.Alzheimer's Disease: Biology, Biophysics and Computational Models helps the reader to understand AD from mechanistic and biochemical perspectives at intra- and inter-cellular levels. It focuses on biochemical pathways and modeling associated with AD. Some of the recent research on biophysics and computational models related to AD are explained using context-driven computational and mathematical modeling and essential biology is discussed to understand the modeling research.
Download or read book Alzheimer s Disease written by Thimmaiah Govindaraju and published by Royal Society of Chemistry. This book was released on 2022-01-04 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease is an increasingly common form of dementia and despite rising interest in discovery of novel treatments and investigation into aetiology, there are no currently approved treatments that directly tackle the causes of the condition. Due to its multifactorial pathogenesis, current treatments are directed against symptoms and even precise diagnosis remains difficult as the majority of cases are diagnosed symptomatically and usually confirmed only by autopsy. Alzheimer’s Disease: Recent Findings in Pathophysiology, Diagnostic and Therapeutic Modalities provides a comprehensive overview from aetiology and neurochemistry to diagnosis, evaluation and management of Alzheimer's disease, and latest therapeutic approaches. Intended to provide an introduction to all aspects of the disease and latest developments, this book is ideal for students, postgraduates and researchers in neurochemistry, neurological drug discovery and Alzheimer’s disease.
Download or read book Systems Biology of Alzheimer s Disease written by Juan I. Castrillo and published by Humana. This book was released on 2016-10-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease (AD) and many other neurodegenerative disorders are multifactorial in nature, involving a combination of genomic, epigenomic, network dynamic and environmental factors. A proper investigation requires new integrative Systems Biology approaches, at both the experimental and computational level. The interplay of disease mechanisms and homeostatic networks will underlie the time of onset and rate of progression of the disease. This book addresses such an integrated approach to AD. It aims to present Systems Biology, including both experimental and computational approaches, as a new strategy for the study of AD and other multifactorial diseases, with the hope that the results will translate into more effective diagnosis and treatment, as well as improved public health policies. Written for the highly successful Methods in Molecular Biology series, practical and cutting-edge, Systems Biology of Alzheimer’s Disease is intended for post-graduate students, post-doctoral researchers and experts in different fields with an interest in comprehensive Systems Biology strategies applicable to AD and other complex multifactorial diseases (including other neurodegenerative diseases and cancers). This book aims to complement other excellent volumes and monographs on AD that cover fundamental, physiological or medical aspects of the disease.
Download or read book Computational and Experimental Simulations in Engineering written by Shaofan Li and published by Springer Nature. This book was released on 2023-11-30 with total page 1435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers the latest advances, innovations, and applications in the field of computational engineering, as presented by leading international researchers and engineers at the 29th International Conference on Computational & Experimental Engineering and Sciences (ICCES), held in Shenzhen, China on May 26-29, 2023. ICCES covers all aspects of applied sciences and engineering: theoretical, analytical, computational, and experimental studies and solutions of problems in the physical, chemical, biological, mechanical, electrical, and mathematical sciences. As such, the book discusses highly diverse topics, including composites; bioengineering & biomechanics; geotechnical engineering; offshore & arctic engineering; multi-scale & multi-physics fluid engineering; structural integrity & longevity; materials design & simulation; and computer modeling methods in engineering. The contributions, which were selected by means of a rigorous international peer-review process, highlight numerous exciting ideas that will spur novel research directions and foster multidisciplinary collaborations.
Download or read book Alzheimer s Disease written by Renee D. Wegrzyn and published by CRC Press. This book was released on 2012-04-26 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, a tremendous amount of effort has been focused on better understanding the fundamentals of Alzheimer's disease (AD) to facilitate early and accurate diagnosis and appropriately targeted therapeutic treatments. Alzheimer's Disease: Targets for New Clinical, Diagnostic, and Therapeutic Strategies provides a detailed synopsis of the c
Download or read book Biosensors Nanotechnology written by Inamuddin and published by John Wiley & Sons. This book was released on 2023-09-13 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: BIOSENSORS NANOTECHNOLOGY The second edition of Biosensors Nanotechnology comprises 20 chapters and discusses a wide range of applications exploited by biosensors based on nanoparticles including new domains of bionics, power production and computing. The biosensor industry began as a small, niche activity in the 1980s and has since developed into a large, global industry. Nanomaterials have substantially improved not only non-pharmaceutical and healthcare uses, but also telecommunications, paper, and textile manufacturing. Biological sensing assists in the understanding of living systems and is used in a variety of sectors, including medicine, drug discovery, process control, environmental monitoring, food safety, military and personal protection. It allows for new opportunities in bionics, power generation and computing, all of which will benefit from a greater understanding of the bio-electronic relationship, as advances in communications and computational modeling enable us to reconsider how healthcare is offered and R&D and manufacturing are enhanced. In this fast-evolving discipline, the combination of nanoscale materials with biosensor technology has gained a lot of traction. Nanostructures have been used to increase the adherence of biosensor materials to electrode surfaces, print nano barcodes on biomaterials, increase the pace of bio-responses, and amplify the electric signal. Some of the topics discussed in the book include: Bioreceptors for Cells; Bioreceptors for Enzymatic Interactions; Dendrimer-Based Nanomaterials for Biosensors; Biosensors in 2D Photonic Crystals; Bioreceptors for Affinity Binding in Theranostic Development; Biosensors for Glucose Monitoring; Metal-Free Quantum Dots-Based Nanomaterials for Biosensors; Bioreceptors for Microbial Biosensors; Plasmonic Nanomaterials in Sensors; Magnetic Biosensors; Biosensors for Salivary Biomarker Detection of Cancer and Neurodegenerative Diseases; Design and Development of Fluorescent Chemosensors for the Recognition of Biological Amines and Their Cell Imaging Studies; Application of Optical Nanoprobes for Supramolecular Biosensing; In Vivo Applications for Nanomaterials in Biosensors; Biosensor and Nanotechnology for Diagnosis of Breast Cancer; Bioreceptors for Antigen–Antibody Interactions; Biosensors for Paint and Pigment Analysis; Bioreceptors for Tissue; Biosensors for Pesticide Detection; and Advances in Biosensor Applications for Agroproducts Safety. Audience The book is written for a large and broad readership including researchers, industry engineers, and university graduate students from diverse backgrounds such as chemistry, materials science, physics, pharmacy, medical science, biomedical engineering, electronics engineering, and nanotechnology.
Download or read book The Alzheimer s Disease Challenge Volume II written by Mohammad Amjad Kamal and published by Frontiers Media SA. This book was released on 2024-04-15 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given the success of Volume I of this Research Topic, we are pleased to announce the launch of Volume II: “The Alzheimer's Disease Challenge”. The repeated failure of clinical trials on the amyloid-based medications and the pessimistic calculations of Alzheimer's disease cost burden for the next few decades present a severe challenge to humankind with severe social implications. In recent years, several alternative diagnostic and treatment procedures have been presented to treat and manage Alzheimer’s disease as it has been nearly impossible to suggest a holistic solution. Several revelations in human biology have highlighted the multiparametric character of the disease. Besides the amyloid aggregation and neurofibrillary tangles that result in Aβ toxicity and tau phosphorylation, processes such as Gene Mutations, Proteins Misfolding, Brain Biochemical and Histopathological Changes, Behavioral Changes, Nutrition and Metabolism Alterations, and Autonomic Dysfunctions due to Central Nervous System dysregulations are common signs and probably early diagnostic biomarkers in most of the Alzheimer's classification categories.
Download or read book SERS for Point of care and Clinical Applications written by Andrew Fales and published by Elsevier. This book was released on 2022-08-12 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: SERS for Point-of-care and Clinical Applications focuses on the use of Surface-Enhanced Raman Spectroscopy (also known as Surface-Enhanced Raman Scattering) techniques in clinical and point-of-care settings. Sections provide an overview of SERS biomedical applications, providing in-depth information about point-of-care and clinical applications of SERS using specific examples from current literature. These applications are not always immediately evident to newcomers in the field, as Raman and SERS are often introduced as analytical methods for chemical analysis. This book offers a concise introduction to the biomedical applications of SERS for graduate students, scientists and researchers in all related fields. Highlights point-of-care applications for SERS Covers the recent biomedical applications of SERS carried out by leaders in the field Includes chapters on SERS probes and labels and label-free uses of SERS
Download or read book Misbehaving Proteins written by Regina Murphy and published by Springer Science & Business Media. This book was released on 2007-10-12 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides an up-to-date collection of theoretical and experimental studies into protein folding, misfolding, aggregation, and stability. Additionally, issues faced during the development of protein products are illustrated. It contains an introductory chapter for readers new to the protein folding field. The book provides a thorough and clear discussion of computational approaches to understanding and modeling protein aggregation.
Download or read book Computational Immunology written by Shyamasree Ghosh and published by CRC Press. This book was released on 2020-01-31 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Immunology: Applications focuses on different mathematical models, statistical tools, techniques, and computational modelling that helps in understanding complex phenomena of the immune system and its biological functions. The book also focuses on the latest developments in computational biology in designing of drugs, targets, biomarkers for early detection and prognosis of a disease. It highlights the applications of computational methods in deciphering the complex processes of the immune system and its role in health and disease. This book discusses the most essential topics, including Next generation sequencing (NGS) and computational immunology Computational modelling and biology of diseases Drug designing Computation and identification of biomarkers Application in organ transplantation Application in disease detection and therapy Computational methods and applications in understanding of the invertebrate immune system S Ghosh is MSc, PhD, PGDHE, PGDBI, is PhD from IICB, CSIR, Kolkata, awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.
Download or read book Computational Epigenetics and Diseases written by and published by Academic Press. This book was released on 2019-02-06 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA, are summarized, in the context of human diseases. This book discusses bioinformatics methods for epigenetic analysis specifically applied to human conditions such as aging, atherosclerosis, diabetes mellitus, schizophrenia, bipolar disorder, Alzheimer disease, Parkinson disease, liver and autoimmune disorders, and reproductive and respiratory diseases. Additionally, different organ cancers, such as breast, lung, and colon, are discussed. This book is a valuable source for graduate students and researchers in genetics and bioinformatics, and several biomedical field members interested in applying computational epigenetics in their research. Provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases Summarizes the major computational tools, databases, and strategies for computational epigenetics analysis, such as DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA Covers the major milestones and future directions of computational epigenetics in various kinds of human diseases such as aging, atherosclerosis, diabetes, heart disease, neurological disorders, cancers, blood disorders, liver diseases, reproductive diseases, respiratory diseases, autoimmune diseases, human imprinting disorders, and infectious diseases
Download or read book Advanced Computational Paradigms and Hybrid Intelligent Computing written by Tapan Kumar Gandhi and published by Springer Nature. This book was released on 2021-12-06 with total page 653 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents high-quality, peer-reviewed papers from the Third International Conference on Advanced Computational and Communication Paradigms (ICACCP 2021), organized by Department of Computer Science and Engineering (CSE), Sikkim Manipal Institute of Technology (SMIT), Sikkim, India during 22 – 24 March 2021. ICACCP 2021 covers an advanced computational paradigms and communications technique which provides failsafe and robust solutions to the emerging problems faced by mankind. Technologists, scientists, industry professionals and research scholars from regional, national and international levels are invited to present their original unpublished work in this conference.
Download or read book Pattern Recognition in Computational Molecular Biology written by Mourad Elloumi and published by John Wiley & Sons. This book was released on 2015-11-30 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of high-performance pattern recognition techniques and approaches to Computational Molecular Biology This book surveys the developments of techniques and approaches on pattern recognition related to Computational Molecular Biology. Providing a broad coverage of the field, the authors cover fundamental and technical information on these techniques and approaches, as well as discussing their related problems. The text consists of twenty nine chapters, organized into seven parts: Pattern Recognition in Sequences, Pattern Recognition in Secondary Structures, Pattern Recognition in Tertiary Structures, Pattern Recognition in Quaternary Structures, Pattern Recognition in Microarrays, Pattern Recognition in Phylogenetic Trees, and Pattern Recognition in Biological Networks. Surveys the development of techniques and approaches on pattern recognition in biomolecular data Discusses pattern recognition in primary, secondary, tertiary and quaternary structures, as well as microarrays, phylogenetic trees and biological networks Includes case studies and examples to further illustrate the concepts discussed in the book Pattern Recognition in Computational Molecular Biology: Techniques and Approaches is a reference for practitioners and professional researches in Computer Science, Life Science, and Mathematics. This book also serves as a supplementary reading for graduate students and young researches interested in Computational Molecular Biology.
Download or read book Alzheimer s Disease written by Thimmaiah Govindaraju and published by Royal Society of Chemistry. This book was released on 2022-01-12 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook on Alzheimer's disease from aetiology and neurochemistry to diagnostic and therapeutic approaches. Intended to provide an introduction to all aspects of the disease.
Download or read book Theory and Applications of Ordered Fuzzy Numbers written by Piotr Prokopowicz and published by Springer. This book was released on 2017-10-18 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This open access book offers comprehensive coverage on Ordered Fuzzy Numbers, providing readers with both the basic information and the necessary expertise to use them in a variety of real-world applications. The respective chapters, written by leading researchers, discuss the main techniques and applications, together with the advantages and shortcomings of these tools in comparison to other fuzzy number representation models. Primarily intended for engineers and researchers in the field of fuzzy arithmetic, the book also offers a valuable source of basic information on fuzzy models and an easy-to-understand reference guide to their applications for advanced undergraduate students, operations researchers, modelers and managers alike.
